$59 Find Cheap Flights from Minneapolis to South Carolina

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Minneapolis to South Carolina departing on 5/11. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to South Carolina

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Minneapolis to South Carolina.
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Minneapolis to South Carolina.
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Cheap Flights from Minneapolis to South Carolina

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Charleston
Charlestonnonstop$167
Myrtle Beach
Myrtle Beachnonstop$217
Greenville
Greenville2 stops$300
Columbia
Columbia1 stop$259
Florence
Florence1 stop$355
Charlotte
Charlotte2 stops$253
Charleston
Charlestonnonstop$167
Myrtle Beach
Myrtle Beachnonstop$217
Greenville
Greenville2 stops$300
Columbia
Columbia1 stop$259
Florence
Florence1 stop$355
Charlotte
Charlotte2 stops$253

Book Cheap Minneapolis to South Carolina Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Minneapolis to South Carolina that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Minneapolis to South Carolina

Sun, May 3 - Sun, May 10
Sun Country Air Logo
7:25 am - 11:07 amMSP-CHS
2h 42mnonstop
Sun Country Air Logo
12:23 pm - 2:24 pmCHS-MSP
3h 01mnonstop
$167Sun Country Air
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Thu, Apr 30 - Thu, May 7
Sun Country Air Logo
7:25 am - 11:07 amMSP-CHS
2h 42mnonstop
Sun Country Air Logo
12:22 pm - 2:23 pmCHS-MSP
3h 01mnonstop
$208Sun Country Air
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Tue, Dec 2 - Sat, Dec 13
Delta Logo
4:30 pm - 11:43 pmMSP-MYR
6h 13m1 stop
Delta Logo
6:00 am - 10:08 amMYR-MSP
5h 08m1 stop
$251Delta
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Thu, Dec 25 - Tue, Dec 30
American Airlines Logo
6:20 am - 10:02 amMSP-CLT
2h 42mnonstop
American Airlines Logo
9:40 pm - 11:22 pmCLT-MSP
2h 42mnonstop
$255American Airlines
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Tue, Dec 2 - Sat, Dec 13
American Airlines Logo
12:51 pm - 10:36 pmMSP-MYR
8h 45m2 stops
American Airlines Logo
6:00 am - 12:50 pmMYR-MSP
7h 50m1 stop
$256American Airlines
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Sun, Feb 8 - Wed, Feb 11
Delta Logo
7:00 am - 3:04 pmMSP-MYR
7h 04m1 stop
Delta Logo
6:00 am - 10:17 amMYR-MSP
5h 17m1 stop
$265Delta
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Thu, Dec 11 - Sun, Dec 14
United Airlines Logo
8:00 am - 4:43 pmMSP-CAE
7h 43m1 stop
United Airlines Logo
2:22 pm - 7:40 pmCAE-MSP
6h 18m1 stop
$275United Airlines
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Thu, Jan 29 - Mon, Feb 2
Southwest Logo
7:20 am - 2:25 pmMSP-MYR
6h 05m1 stop
Southwest Logo
3:00 pm - 9:15 pmMYR-MSP
7h 15m1 stop
$279Southwest
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Thu, Dec 11 - Sun, Dec 14
United Airlines Logo
6:00 am - 2:15 pmMSP-CAE
7h 15m2 stops
United Airlines Logo
2:22 pm - 7:40 pmCAE-MSP
6h 18m1 stop
$280United Airlines
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Tue, Jan 6 - Sat, Jan 10
Southwest Logo
7:20 am - 5:35 pmMSP-GSP
9h 15m2 stops
Southwest Logo
10:50 am - 2:20 pmGSP-MSP
4h 30m1 stop
$322Southwest
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Booking Insights

KAYAK's insights & trends for Minneapolis to South Carolina flights

Get data-powered insights and trends into flights from Minneapolis to South Carolina to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest Minneapolis to South Carolina flight route?

Data is based on round-trip flight searches on KAYAK over the past month.

The cheapest ticket to South Carolina from Minneapolis found in the last 72 hours was to Myrtle Beach, at $158 round-trip. The most popular route is from Minneapolis (MSP) to Charleston (CHS), and the cheapest round-trip airline ticket found on this route in the last 72 hours was $228.

Can I save money by flying with a layover from Minneapolis to South Carolina?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

No, with an average price for the route of $345, prices are generally cheapest when you fly direct.

What is the cheapest month to fly from Minneapolis to South Carolina?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Minneapolis to South Carolina, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Minneapolis to South Carolina is June, when tickets cost $298 (return) on average. On the other hand, the most expensive months are March and December, when the average cost of round-trip tickets is $478 and $378 respectively.

What’s the cheapest day of the week to fly from Minneapolis to South Carolina?

The average price of all round-trip flights from Minneapolis to South Carolina clicked on KAYAK for each day over the last 12 months.

When flying from Minneapolis to South Carolina, you should consider leaving on a Sunday and avoid Thursdays if you are looking for the best rates. For your return to Minneapolis, you’ll find the best rates on Thursdays and the most expensive ones on Mondays.

How far in advance should I book a flight from Minneapolis to South Carolina?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Minneapolis to South Carolina, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Minneapolis to South Carolina, you should book around 4 weeks before departure, which saves you about 44% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 18 weeks before departure.

Good to know

Low seasonDecember
Cheapest flight$59
Best time to beat the crowds but there is an average 1% increase in price.
Most popular time to fly with an average 24% increase in price.
Flight from Minneapolis to Myrtle Beach

FAQs - booking South Carolina flights

  • How does KAYAK find such low prices on flights from Minneapolis to South Carolina?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Minneapolis to South Carolina.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Minneapolis to South Carolina?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Minneapolis to South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Minneapolis to South Carolina?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Minneapolis to South Carolina with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Minneapolis to South Carolina?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Minneapolis to South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to South Carolina?

    The cheapest time of day to fly to South Carolina is generally in the morning, when round-trip flights cost $349 on average. The most expensive time of day to fly to South Carolina is generally in the afternoon, which is peak travel time and where the average cost of a ticket is $598.

Top tips for finding cheap flights to South Carolina

  • Looking for a cheap flight? 25% of our users found tickets from Minneapolis to the following destinations at these prices or less: Charlotte $173 one-way - $305 round-trip

Reviews of the top 5 airlines serving from Minneapolis to South Carolina

 
See real verified KAYAK customer reviews for airlines flying from Minneapolis to South Carolina. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Minneapolis to South Carolina? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
SouthwestOverall score based on 4244 reviews
8.0Comfort
8.6Crew
7.0Food
8.1Boarding
7.5Entertainment
Airline reviews

No delays and arrived to destination 30 min early. Staff was super friendly.

10.0 ExcellentIlevba, Nov 2025DCA - DAL
Read more Southwest reviews

No delays and arrived to destination 30 min early. Staff was super friendly.

San Diego airport is brand new, spacious, airy and very smooth checkin at SW baggage drop.

It was rough. The staff was unprofessional, the choice of on board drinks terrible, it was cramped in space at every airport, they always ran out of overhead bin space so they pressured people to check bags for free or we couldn’t leave on the plane— so I did check my bag to help, and they nearly lost my bag. My bag did not arrive on the luggage belt, another man on my flight and I had to waste our time going to the baggage office to search for our bags. I would only fly southwest again if it was my last choice. Also, my flights were consistently delayed over and over again— at one point they straight up told us we were waiting for the pilot to arrive.

Crew could have been friendlier, maybe I'm spoiled by SW crews. In flight wifi was good. Would be nice to have more food offerings on a 4 plus hour flight

Had to get off plane from prior flight even though I had to reboard same plane to continue to my final destination.

Everything a cheap airline should be at normal airline rates.

Plane crashed into a bus or some other vehicle on the ground while pulling out of the gate. No injuries, but wing tip was damaged and returned to gate for “maintenance issues” and we departed 5 hours later because the plane went out of service and new plane was flown in from a nearby airport, Midway.

Ever since Southwest starting charging for bags, passengers don't want to pay to check their bags, so the gate agents have to beg people to check their roller bags now because there's "not enough space". This was a terrible business move by Southwest.

Full cans of soda would be nice. A choice between two snacks would be appreciated.

Tried watching free movie and it kept freezing so I couldn’t finish.

Service in business class was not impressive. I ordered coffee with dinner and then watched other people get 2 refills before I got my 1 cup of coffee, and only after I pressed the attendant button overhead. Furthermore, the seats in the forward cabin need maintenance on this 737-800: the upholstery is detaching from the seat frame, at least on the backs of seats 1C, 1D.

The ticket agents in West Palm Beach on Friday afternoon Nov. 7th were incredible in getting us on an earlier plane to Atlanta during the government shutdown. Had the taken our original flight we would have missed our connection. She did this on her own, We didn't even have to ask, and she did it all with a smile and showing genuine concern that we would be taken care of. We are very grateful and thankful. We fly often, and now we will be sure to fly Delta.

Flight delayed then cancelled. Misplaced luggage. Still do not have. Rented car 1100 mile drive. I had to buy some overnight Hotels clothes toiletries gas food at my expense. Still not home. Not sure where luggage is. Over 4 hours on hold to Felta

I truly love flying with Delta. They have always treated me with the upmost respect

Our flight attendant in FIRST CLASS was one of the worst I’ve ever had. She was not at all pleasant, nor particularly good at her service.

Everything went well and was good. Nothing exceptional, but no complaints either. Cheap seats are pretty comfortable.

Staff were friendly and happy. Delta could make sure passengers that don't have the app know of changes. Without Kayak I would not have known about the change of gate or the delay. Kayak was faster to notify me.

They ended up paying for the bag twice, but the counter wouldn't take my baggage receipt. Left it to me to resolve. Not sure how to resolve the issue.

The customer service before board was very rude and when I expressed my concerns about making the connecting flight she laughed and told me I bought the wrong ticket. I explained once it showed the flight was delayed it no longer let me change seats or anything. I was trying to upgrade to make sure I would get to the next gate on time.

Non stop on long haul is the way to go. Great experience

Even though we were delayed, we were able to make our connection

Starlink wifi on the Embraer E175 is an excellent experience. I was able to connect and work from IAD all the way to approach into BTV.

Older aircraft, no meal, only food was for purchase. Not impressed United.

United needs to step up their game. Delayed flight leaving Seattle, San Francisco. Older aircraft, not very comfortable.

Always wish for more healthy, gluten free options. We have to bring our own.

Having a long layover, I was very appreciative of the ability to stand by for an earlier flight. Other airlines like Delta have refused this to me in the past, just to be mean (because my ticket class wasn't high enough). United went out of their way to help me get to my destination early, which I really appreciated given that it was the third leg of a 24+ hour journey for me.

Other than a way way too cold cabinets for the entire flight, all was great

One bag is incorrect and not acceptable for an international flight. The food was not just good. I won't fly with them again.

Not pleasant trip cross country when the entertainment and WiFi system not working. No entertainment for entirety of route. Staff was rather nonchalant in that they dismissed the problem due to age of plane. It would have been nice to know this up front so I could have come prepared to read or download movies before boarding Coincidentally or not, there was a similar issue with the entertainment system on my previous flight I took on my fist leg of the trip. There are no seat TVs, so you must rely on the app when it works. United can do better. Also, what use it it to pay for boarding group 2 when half of the passengers are in the same line as you?

Plane boarded early a quickly, was mostly full. We left close to on time. And landed early.

More choices on snacks. Built-in video screen to enjoy entertainment choices.

we landed at cmh ten minutes early but had to sit on tarmac for twenty minutes because a plane was at our gate despite the fact that 3 other gates were open.

The experience with American Airlines was good, although the Philippines Airlines flight was much better (better seats, better food, better entertainment options, overall better). Again, the MIA to LAX flight was fine, but nothing in comparison to the comfort and accommodations of the Philippines Airlines flight from LAX to MNL.

I have a gluten allergy so did have any food

I have a gluten allergy so didn't have any food

Loved the crew . Absolutely no complaints. Except for luggage lost

Everything was good The connects, with no blame to crew. Or pilots. I understand they are short staffed. Everything went well for me. I'll be using you guys again in May if not sooner.

this plane was really old, had exit row seats and tray was in arm of seat so super uncomfortable to use. another seat they could t even use the tray it was broke. seat i. front of me had duct tape on it cause seat was ripped open... this plane should either be updated or retired.

Baggage handling poor. Second time this has happened. My bag went to San Francisco instead of Fiji. No apology. Luckily Nadi airport staff are fantastic. My bag arrived in Fiji the next day.

We loved the steward on the plane. He made the night enjoyable

Just fine but comfort is always an issue since the seats are so close

The Flight was fine, the staff treated me well, the flight got delayed over 5 1/2 hours for maintenance issues....but it worked out OK,, they were very apologetic about it, and it is better to not fly if there is any issue than endanger peoples lives, so in reality that was a good thing, It did cost me extra for parking because I went beyond the time I had purchased for parking at MSP. But all in all, Good flight

I did not take this flight because the reservation made by Kayak was wrong! Kayak owes me a trip from Minneapolis to Duluth.

When I got to the airport in Seattle, they told me the flight "did not exist". Kayak reserved me a seat on a flight that did not exist. This is inexcusable. I was able to change my reservation to a flight that actually did exist, but the flight was later and then I didn't make it in time for the next leg of my trip from Minneapolis to Duluth. Kayak owes me a trip from Minneapolis to Duluth, and a big apology for messing up my reservation.

The plane was freezing cold. Asked for a blanket and there were none. Was told twice that the pilots would warm the plane and it never happened Worst experience flying ever

Multiple delays because they screwed up on the crew schedule and had to wait for over an hour for more people to come.

It was good. Basic flight. Drinks only. Pay budget. Get budget and I’m good with that. I want to get where I need to go. Not hard to please. Female First Officer is an absolute bonus for me!

The Wi-Fi was off, the arm rests are hard plastic.

The assistance with the wheel chairs was fabulous. All the people were so very friendly and helpful. I want to thank them all.

We almost missed our return flight. We got to the gate one minute from closing the cabin door, and the agent got us aboard the plane! We are so very grateful!!!!!

Everything you need to know for your flight from Minneapolis to South Carolina

Information on your arrival and departure airports