How does KAYAK find such low prices on flights from Missouri to Chicago?

KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Missouri to Chicago.

How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Missouri to Chicago?

KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Chicago from Missouri is likely to change within 7 days, so travelers know whether to wait or book now.

What is the Hacker Fare option on flights from Missouri to Chicago?

Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Chicago with an airline and back to Missouri with another airline.

What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Missouri to Chicago?

Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Chicago from Missouri up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

$47 CHEAP FLIGHTS from Missouri to Chicago

Save 21% or more on flights. Compare deals from all over the web.

Never overpay with our price tracking tools.

Filter searches by price, airline and more to find your best flights.

Flight Deals

Cheap Flights from Missouri to Chicago

Discover the best prices for you by selecting your travel dates on KAYAK.

Round-trip

One-way

Last minute

Direct

Recent round-trip flight deals from Missouri to Chicago

Sat, Sep 5 - Wed, Sep 9

3:25 pm - 5:10 pmUIN Quincy Regional-ORD Chicago O'Hare Intl

1h 45mnonstop

12:30 pm - 1:55 pmORD Chicago O'Hare Intl-UIN Quincy Regional

1h 25mnonstop

$102Contour

Thu, Oct 15 - Sat, Oct 17

9:55 am - 11:40 amUIN Quincy Regional-ORD Chicago O'Hare Intl

1h 45mnonstop

12:30 pm - 1:55 pmORD Chicago O'Hare Intl-UIN Quincy Regional

1h 25mnonstop

$103Contour

Thu, Oct 22 - Sat, Oct 24

5:00 am - 6:26 amSTL Lambert-St Louis-ORD Chicago O'Hare Intl

1h 26mnonstop

7:50 pm - 9:13 pmORD Chicago O'Hare Intl-STL Lambert-St Louis

1h 23mnonstop

$117American Airlines

Mon, Sep 21 - Wed, Sep 23

5:00 am - 6:29 amSTL Lambert-St Louis-ORD Chicago O'Hare Intl

1h 29mnonstop

8:55 am - 10:18 amORD Chicago O'Hare Intl-STL Lambert-St Louis

1h 23mnonstop

$117American Airlines

Mon, Nov 2 - Mon, Nov 2

5:00 am - 6:36 amSTL Lambert-St Louis-ORD Chicago O'Hare Intl

1h 36mnonstop

10:00 pm - 11:24 pmORD Chicago O'Hare Intl-STL Lambert-St Louis

1h 24mnonstop

$117United Airlines

Wed, Sep 30 - Wed, Sep 30

8:00 am - 9:31 amSTL Lambert-St Louis-ORD Chicago O'Hare Intl

1h 31mnonstop

7:50 pm - 9:21 pmORD Chicago O'Hare Intl-STL Lambert-St Louis

1h 31mnonstop

$117United Airlines

Mon, Oct 19 - Thu, Oct 22

10:00 pm - 11:05 pmSTL Lambert-St Louis-MDW Chicago Midway

1h 05mnonstop

11:05 am - 12:15 pmMDW Chicago Midway-STL Lambert-St Louis

1h 10mnonstop

$117Southwest

Mon, Sep 21 - Wed, Sep 23

8:50 pm - 10:00 pmSTL Lambert-St Louis-MDW Chicago Midway

1h 10mnonstop

2:00 pm - 3:10 pmMDW Chicago Midway-STL Lambert-St Louis

1h 10mnonstop

$117Southwest

Thu, Oct 1 - Mon, Oct 5

10:20 am - 7:35 pmSTL Lambert-St Louis-ORD Chicago O'Hare Intl

9h 15m1 stop Dallas/Fort Worth

8:55 pm - 11:32 amORD Chicago O'Hare Intl-STL Lambert-St Louis

14h 37m1 stop Las Vegas Harry Reid Intl

$118Frontier

Sat, Sep 12 - Mon, Sep 14

12:17 pm - 5:38 amSTL Lambert-St Louis-ORD Chicago O'Hare Intl

17h 21m1 stop Las Vegas Harry Reid Intl

8:55 pm - 11:32 amORD Chicago O'Hare Intl-STL Lambert-St Louis

14h 37m1 stop Las Vegas Harry Reid Intl

$118Frontier

Recent last minute flight deals from Missouri to Chicago

Sun, Aug 30 - Sun, Sep 27

6:41 pm - 8:30 pmCOU Columbia Regional-ORD Chicago O'Hare Intl

1h 49mnonstop

8:24 am - 9:56 amORD Chicago O'Hare Intl-COU Columbia Regional

1h 32mnonstop

$294American Airlines

Sat, Aug 29 - Sat, Sep 5

1:38 pm - 1:36 pmMCI Kansas City-ORD Chicago O'Hare Intl

23h 58m1 stop Denver Intl

7:11 am - 4:05 pmORD Chicago O'Hare Intl-MCI Kansas City

8h 54m1 stop Atlanta Hartsfield-Jackson

$312Frontier

Wed, Aug 26 - Wed, Sep 2

11:26 am - 8:08 pmMCI Kansas City-ORD Chicago O'Hare Intl

8h 42m1 stop Atlanta Hartsfield-Jackson

2:41 pm - 12:53 pmORD Chicago O'Hare Intl-MCI Kansas City

22h 12m1 stop Denver Intl

$315Frontier

Fri, Aug 28 - Sun, Aug 30

6:15 am - 7:54 amCOU Columbia Regional-ORD Chicago O'Hare Intl

1h 39mnonstop

8:40 am - 10:16 amORD Chicago O'Hare Intl-COU Columbia Regional

1h 36mnonstop

$339United Airlines

Fri, Aug 28 - Sun, Aug 30

6:35 pm - 8:24 pmCOU Columbia Regional-ORD Chicago O'Hare Intl

1h 49mnonstop

10:45 am - 12:13 pmORD Chicago O'Hare Intl-COU Columbia Regional

1h 28mnonstop

$339American Airlines

Sat, Aug 29 - Mon, Aug 31

8:30 am - 10:28 amJLN Joplin-ORD Chicago O'Hare Intl

1h 58mnonstop

11:29 am - 1:18 pmORD Chicago O'Hare Intl-JLN Joplin

1h 49mnonstop

$341United Airlines

Fri, Aug 28 - Mon, Aug 31

9:50 am - 11:45 amCGI Cape Girardeau-ORD Chicago O'Hare Intl

1h 55mnonstop

11:15 am - 12:50 pmORD Chicago O'Hare Intl-CGI Cape Girardeau

1h 35mnonstop

$356Contour

Fri, Aug 28 - Sun, Aug 30

6:58 pm - 11:57 pmSGF Springfield-Branson-ORD Chicago O'Hare Intl

4h 59m1 stop Atlanta Hartsfield-Jackson

5:30 am - 10:53 amORD Chicago O'Hare Intl-SGF Springfield-Branson

5h 23m1 stop Atlanta Hartsfield-Jackson

$369Delta

Sat, Aug 29 - Wed, Sep 2

11:38 am - 4:51 pmSGF Springfield-Branson-ORD Chicago O'Hare Intl

5h 13m1 stop Atlanta Hartsfield-Jackson

3:25 pm - 10:21 pmORD Chicago O'Hare Intl-SGF Springfield-Branson

6h 56m1 stop Atlanta Hartsfield-Jackson

$369Delta

Fri, Aug 28 - Mon, Aug 31

9:50 am - 11:45 amCGI Cape Girardeau-ORD Chicago O'Hare Intl

1h 55mnonstop

2:40 pm - 8:35 pmORD Chicago O'Hare Intl-CGI Cape Girardeau

29h 55m2 stops Kirksville Cannon Memorial Dallas/Fort Worth

$375Contour

Recent direct flight deals from Missouri to Chicago

Sat, Sep 5 - Wed, Sep 9

3:25 pm - 5:10 pmUIN Quincy Regional-ORD Chicago O'Hare Intl

1h 45mnonstop

12:30 pm - 1:55 pmORD Chicago O'Hare Intl-UIN Quincy Regional

1h 25mnonstop

$102Contour

Thu, Oct 15 - Sat, Oct 17

9:55 am - 11:40 amUIN Quincy Regional-ORD Chicago O'Hare Intl

1h 45mnonstop

12:30 pm - 1:55 pmORD Chicago O'Hare Intl-UIN Quincy Regional

1h 25mnonstop

$103Contour

Fri, Nov 13 - Sat, Nov 14

9:55 am - 11:40 amUIN Quincy Regional-ORD Chicago O'Hare Intl

1h 45mnonstop

12:30 pm - 1:55 pmORD Chicago O'Hare Intl-UIN Quincy Regional

1h 25mnonstop

$103Contour

Thu, Dec 3 - Sat, Dec 5

5:00 am - 6:29 amSTL Lambert-St Louis-ORD Chicago O'Hare Intl

1h 29mnonstop

3:18 pm - 4:46 pmORD Chicago O'Hare Intl-STL Lambert-St Louis

1h 28mnonstop

$117American Airlines

Thu, Sep 17 - Thu, Sep 24

5:00 am - 6:29 amSTL Lambert-St Louis-ORD Chicago O'Hare Intl

1h 29mnonstop

11:05 pm - 12:27 amORD Chicago O'Hare Intl-STL Lambert-St Louis

1h 22mnonstop

$117American Airlines

Wed, Sep 30 - Wed, Sep 30

8:00 am - 9:31 amSTL Lambert-St Louis-ORD Chicago O'Hare Intl

1h 31mnonstop

7:50 pm - 9:21 pmORD Chicago O'Hare Intl-STL Lambert-St Louis

1h 31mnonstop

$117United Airlines

Thu, Oct 1 - Mon, Oct 5

6:00 am - 7:36 amSTL Lambert-St Louis-ORD Chicago O'Hare Intl

1h 36mnonstop

7:50 pm - 9:21 pmORD Chicago O'Hare Intl-STL Lambert-St Louis

1h 31mnonstop

$117United Airlines

Mon, Oct 5 - Thu, Oct 8

10:00 pm - 11:05 pmSTL Lambert-St Louis-MDW Chicago Midway

1h 05mnonstop

10:05 pm - 11:15 pmMDW Chicago Midway-STL Lambert-St Louis

1h 10mnonstop

$117Southwest

Thu, Sep 17 - Thu, Sep 24

8:50 pm - 10:00 pmSTL Lambert-St Louis-MDW Chicago Midway

1h 10mnonstop

9:20 am - 10:30 amMDW Chicago Midway-STL Lambert-St Louis

1h 10mnonstop

$117Southwest

Mon, Oct 19 - Thu, Oct 22

5:00 am - 6:26 amSTL Lambert-St Louis-ORD Chicago O'Hare Intl

1h 26mnonstop

11:05 am - 12:35 pmORD Chicago O'Hare Intl-STL Lambert-St Louis

1h 30mnonstop

$117American Airlines

Useful Info

Low season	February
High season	October
Cheapest flight	$47

Best time to beat the crowds but there is an average 2% increase in price.

Most popular time to fly and prices are also 7% lower on average.

Flight from Quincy to Chicago

Verified travelerFlew with American Airlines-May 2026

Arrive airport early, esp if checking bags - std procedure but vital here

valerieFlew with Air Canada-Jan 2025

Usually it is unreliable - always leave lots of time for connection.

How does KAYAK find such low prices on flights from Missouri to Chicago?
KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Missouri to Chicago.
How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Missouri to Chicago?
KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Chicago from Missouri is likely to change within 7 days, so travelers know whether to wait or book now.
What is the Hacker Fare option on flights from Missouri to Chicago?
Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Chicago with an airline and back to Missouri with another airline.
What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Missouri to Chicago?
Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Chicago from Missouri up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Merrillville

Saint Joseph

Hammond

Portage

Lansing

Valparaiso

Munster

Schererville

Chesterton

Porter

Monticello

Saint John

Griffith

Everything you need to know for your flight to Chicago

Cabin class

Complete your trip

Direct Flights

Flights to other cities

Origins

Other airports

Return flight deals

Cabin class types available on flights to Missouri

First Class flights to Chicagofrom $319

Business Class flights to Chicagofrom $358

Premium Economy Class flights to Chicagofrom $758

Economy Class flights to Chicagofrom $117

$47 Find Cheap Flights from Missouri to Chicago - Compare and Save

Cheap Flights from Missouri to Chicago

Recent round-trip flight deals from Missouri to Chicago

Recent one-way flight deals from Missouri to Chicago

Recent last minute flight deals from Missouri to Chicago

Recent direct flight deals from Missouri to Chicago

Good to know

Low season

High season

Cheapest flight

Flights from Missouri to Chicago: the best tips from KAYAK users

FAQs for booking flights from Missouri to Chicago

Traveling to a place near Chicago?

Everything you need to know for your flight to Chicago

Cabin class types available on flights to Missouri

Complete your trip to Chicago with a hotel stay or car rental

Find direct flights for Chicago

Flights to other popular destinations

Flights from domestic origins to Chicago

Choose which airport to fly into in Chicago

Find deals for your return flight