ORD

$48 Find Cheap Flights from Missouri to Chicago O'Hare Airport - Compare and Save

1 adult
1 adult, Economy, 0 bags

Save 21% or more on flights. Compare deals from all over the web.

Never overpay with our price tracking tools.

Filter searches by price, airline and more to find your best flights.

Flight Deals
Useful Info
Flight Deals

Cheap Flights from Missouri to O'Hare Intl

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Missouri to O'Hare Intl

Fri, Sep 25 - Mon, Sep 28
Contour Logo
9:55 am - 11:40 amUIN  Quincy Regional-ORD Chicago O'Hare Intl
1h 45mnonstop
Contour Logo
12:30 pm - 1:55 pmORD  Chicago O'Hare Intl-UIN Quincy Regional
1h 25mnonstop
$95Contour
Sat, Sep 26 - Sun, Sep 27
Contour Logo
3:25 pm - 5:10 pmUIN  Quincy Regional-ORD Chicago O'Hare Intl
1h 45mnonstop
Contour Logo
12:30 pm - 1:55 pmORD  Chicago O'Hare Intl-UIN Quincy Regional
1h 25mnonstop
$95Contour
Tue, Oct 6 - Tue, Oct 6
United Airlines Logo
1:29 pm - 3:00 pmSTL  Lambert-St Louis-ORD Chicago O'Hare Intl
1h 31mnonstop
United Airlines Logo
7:50 pm - 9:21 pmORD  Chicago O'Hare Intl-STL Lambert-St Louis
1h 31mnonstop
$117United Airlines
Wed, Sep 16 - Wed, Sep 23
United Airlines Logo
7:56 am - 9:30 amSTL  Lambert-St Louis-ORD Chicago O'Hare Intl
1h 34mnonstop
United Airlines Logo
8:07 pm - 9:38 pmORD  Chicago O'Hare Intl-STL Lambert-St Louis
1h 31mnonstop
$117United Airlines
Tue, Nov 10 - Thu, Nov 12
American Airlines Logo
7:24 am - 9:00 amSTL  Lambert-St Louis-ORD Chicago O'Hare Intl
1h 36mnonstop
American Airlines Logo
10:39 pm - 11:59 pmORD  Chicago O'Hare Intl-STL Lambert-St Louis
1h 20mnonstop
$117American Airlines
Wed, Sep 16 - Wed, Sep 23
American Airlines Logo
5:00 am - 6:29 amSTL  Lambert-St Louis-ORD Chicago O'Hare Intl
1h 29mnonstop
American Airlines Logo
11:48 am - 1:16 pmORD  Chicago O'Hare Intl-STL Lambert-St Louis
1h 28mnonstop
$117American Airlines
Thu, Oct 15 - Mon, Oct 19
Frontier Logo
5:53 pm - 12:26 amSTL  Lambert-St Louis-ORD Chicago O'Hare Intl
6h 33m1 stop Dallas/Fort Worth
Frontier Logo
6:20 am - 4:58 pmORD  Chicago O'Hare Intl-STL Lambert-St Louis
10h 38m1 stop Dallas/Fort Worth
$118Frontier
Thu, Oct 15 - Mon, Oct 19
Frontier Logo
5:53 pm - 12:26 amSTL  Lambert-St Louis-ORD Chicago O'Hare Intl
6h 33m1 stop Dallas/Fort Worth
Frontier Logo
10:26 am - 5:40 pmORD  Chicago O'Hare Intl-STL Lambert-St Louis
7h 14m1 stop Atlanta Hartsfield-Jackson
$118Frontier
Fri, Sep 25 - Thu, Oct 1
Multiple Airlines Logo
10:30 pm - 12:23 amMCI  Kansas City-ORD Chicago O'Hare Intl
25h 53m2 stops Las Vegas Harry Reid Intl Denver Intl
Multiple Airlines Logo
7:11 am - 8:46 amORD  Chicago O'Hare Intl-MCI Kansas City
25h 35m1 stop Fort Lauderdale
$237Multiple Airlines
Fri, Sep 18 - Mon, Sep 21
Multiple Airlines Logo
2:40 pm - 12:23 amUIN  Quincy Regional-ORD Chicago O'Hare Intl
33h 43m2 stops Nashville Intl Denver Intl
Multiple Airlines Logo
12:30 pm - 1:55 pmORD  Chicago O'Hare Intl-UIN Quincy Regional
1h 25mnonstop
$245Multiple Airlines
Useful Info

Good to know

Low season

January

Cheapest flight

$48
Best time to beat the crowds with an average 14% drop in price.
Most popular time to fly with an average 19% increase in price.
Flight from Quincy to Chicago

Flights from Missouri to O'Hare Intl: the best tips from KAYAK users

Insights shared by verified travelers who flew the route from Missouri to O'Hare Intl 
Verified travelerFlew with American Airlines-May 2026
Arrive airport early, esp if checking bags - std procedure but vital here
valerieFlew with Air Canada-Jan 2025
Usually it is unreliable - always leave lots of time for connection.

FAQs for booking Missouri to Chicago O'Hare Airport flights

  • How does KAYAK find such low prices on flights from Missouri to Chicago O'Hare Airport?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Missouri to Chicago O'Hare Airport.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Missouri to Chicago O'Hare Airport?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Chicago O'Hare Airport from Missouri is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Missouri to Chicago O'Hare Airport?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Chicago O'Hare Airport with an airline and back to Missouri with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Missouri to Chicago O'Hare Airport?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Chicago O'Hare Airport from Missouri up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Traveling to a place near O'Hare Intl?

Book flights to O'Hare Intl if you plan to visit one of these locations
Gurnee
Merrillville
South Haven
Oak Brook
Saint Joseph
Tinley Park
Hammond
Elk Grove Village
Des Plaines
Hoffman Estates
South Holland
Portage
Oakbrook Terrace
Willowbrook
Lansing
Delavan
Alsip
Northbrook
Lisle
Valparaiso

Everything you need to know for your flight to O'Hare Intl

Information on your arrival and departure airports

Chicago O'Hare Airport (ORD)