ORD

$49 Find Cheap Flights from Missouri to Chicago O'Hare Airport - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight to O'Hare Intl departing on 10/29. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Missouri to O'Hare Intl

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Missouri to O'Hare Intl that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Missouri to O'Hare Intl

Tue, Sep 15 - Sat, Oct 3
Contour Logo
3:25 pm - 5:10 pmUIN  Quincy Regional-ORD Chicago O'Hare Intl
1h 45mnonstop
Contour Logo
12:30 pm - 1:55 pmORD  Chicago O'Hare Intl-UIN Quincy Regional
1h 25mnonstop
$95Contour
Wed, Sep 9 - Wed, Sep 16
Contour Logo
9:55 am - 11:40 amUIN  Quincy Regional-ORD Chicago O'Hare Intl
1h 45mnonstop
Contour Logo
12:30 pm - 1:55 pmORD  Chicago O'Hare Intl-UIN Quincy Regional
1h 25mnonstop
$95Contour
Sat, Sep 5 - Sun, Sep 6
American Airlines Logo
5:00 am - 6:24 amSTL  Lambert-St Louis-ORD Chicago O'Hare Intl
1h 24mnonstop
American Airlines Logo
7:00 am - 8:24 amORD  Chicago O'Hare Intl-STL Lambert-St Louis
1h 24mnonstop
$117American Airlines
Sat, Sep 5 - Sun, Sep 6
American Airlines Logo
5:13 pm - 6:52 pmSTL  Lambert-St Louis-ORD Chicago O'Hare Intl
1h 39mnonstop
American Airlines Logo
7:00 am - 8:24 amORD  Chicago O'Hare Intl-STL Lambert-St Louis
1h 24mnonstop
$117American Airlines
Sat, Sep 5 - Sat, Sep 5
United Airlines Logo
8:00 am - 9:34 amSTL  Lambert-St Louis-ORD Chicago O'Hare Intl
1h 34mnonstop
United Airlines Logo
2:00 pm - 3:31 pmORD  Chicago O'Hare Intl-STL Lambert-St Louis
1h 31mnonstop
$117United Airlines
Sat, Sep 5 - Sun, Sep 6
United Airlines Logo
7:25 am - 9:01 amSTL  Lambert-St Louis-ORD Chicago O'Hare Intl
1h 36mnonstop
United Airlines Logo
10:29 am - 12:02 pmORD  Chicago O'Hare Intl-STL Lambert-St Louis
1h 33mnonstop
$117United Airlines
Mon, Sep 21 - Thu, Sep 24
Frontier Logo
2:29 pm - 11:51 amSTL  Lambert-St Louis-ORD Chicago O'Hare Intl
21h 22m1 stop Atlanta Hartsfield-Jackson
Frontier Logo
7:28 pm - 1:10 pmORD  Chicago O'Hare Intl-STL Lambert-St Louis
17h 42m1 stop Atlanta Hartsfield-Jackson
$138Frontier
Thu, Oct 29 - Tue, Nov 3
Frontier Logo
10:35 am - 7:44 pmSTL  Lambert-St Louis-ORD Chicago O'Hare Intl
9h 09m1 stop Atlanta Hartsfield-Jackson
Frontier Logo
6:30 am - 9:40 amORD  Chicago O'Hare Intl-STL Lambert-St Louis
27h 10m1 stop Atlanta Hartsfield-Jackson
$146Frontier
Mon, Sep 28 - Mon, Oct 5
Multiple Airlines Logo
2:40 pm - 10:59 pmUIN  Quincy Regional-ORD Chicago O'Hare Intl
32h 19m2 stops Nashville Intl Orlando
Multiple Airlines Logo
12:30 pm - 1:55 pmORD  Chicago O'Hare Intl-UIN Quincy Regional
1h 25mnonstop
$239Multiple Airlines
Thu, Sep 10 - Wed, Sep 16
Multiple Airlines Logo
9:55 am - 11:40 amUIN  Quincy Regional-ORD Chicago O'Hare Intl
1h 45mnonstop
Multiple Airlines Logo
6:30 am - 9:25 amORD  Chicago O'Hare Intl-UIN Quincy Regional
26h 55m2 stops Denver Intl Nashville Intl
$245Multiple Airlines
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Good to know

Low season

January

Cheapest flight

$49
Best time to beat the crowds with an average 12% drop in price.
Most popular time to fly with an average 17% increase in price.
Flight from Quincy to Chicago

Flights from Missouri to O'Hare Intl: the best tips from KAYAK users

Insights shared by verified travelers who flew the route from Missouri to O'Hare Intl 
Learn how KAYAK collects reviews and tips from users.
Verified travelerFlew with American Airlines-May 2026
Arrive airport early, esp if checking bags - std procedure but vital here
valerieFlew with Air Canada-Jan 2025
Usually it is unreliable - always leave lots of time for connection.

FAQs for booking Missouri to Chicago O'Hare Airport flights

  • How does KAYAK find such low prices on flights from Missouri to Chicago O'Hare Airport?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Missouri to Chicago O'Hare Airport.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Missouri to Chicago O'Hare Airport?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Chicago O'Hare Airport from Missouri is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Missouri to Chicago O'Hare Airport?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Chicago O'Hare Airport with an airline and back to Missouri with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Missouri to Chicago O'Hare Airport?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Chicago O'Hare Airport from Missouri up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Traveling to a place near O'Hare Intl?

Book flights to O'Hare Intl if you plan to visit one of these locations
Gurnee
Merrillville
South Haven
Oak Brook
Saint Joseph
Tinley Park
Hammond
Elk Grove Village
Des Plaines
Hoffman Estates
Portage
South Holland
Willowbrook
Oakbrook Terrace
Lansing
Delavan
Alsip
Northbrook
Lisle
Elmhurst

Everything you need to know for your flight to O'Hare Intl

Information on your arrival and departure airports

Chicago O'Hare Airport (ORD)