ECP - SNA

$219 Find Cheap Flights from Panama City to Santa Ana

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Panama City to Santa Ana departing on 1/16. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Santa Ana

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to Santa Ana, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to Santa Ana, as well as popular online travel agencies
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41,299,237 searches in the past 7 days on KAYAK

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Everything you should know

Cheapest round-trip
$487
Southwest
Tue 12/23Tue 1/6
ECP - SNA • 2 stops
Cheapest one-way
$219
Typical prices: $228-$258
United Airlines
Fri 1/16
ECP - SNA • 1 stop
Top airlines
Southwest
Cheapest • from $487 (round-trip)
American Airlines
Best reviews • 7.2 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
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We hope you love your trip to Santa Ana!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Panama City to Santa Ana (ECP-SNA)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Panama City to Santa Ana that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Panama City to Santa Ana

Tue, Dec 23 - Tue, Jan 6
Southwest Logo
3:30 pm - 9:40 pmECP-SNA
8h 10m2 stops
Southwest Logo
6:40 pm - 9:45 amSNA-ECP
13h 05m2 stops
$487Southwest
Find Deal
Thu, Dec 11 - Sun, Dec 14
American Airlines Logo
6:30 am - 1:57 pmECP-SNA
9h 27m1 stop
American Airlines Logo
12:43 pm - 9:16 pmSNA-ECP
6h 33m1 stop
$497American Airlines
Find Deal
Thu, Dec 11 - Sun, Dec 14
American Airlines Logo
3:18 pm - 8:11 pmECP-SNA
6h 53m1 stop
American Airlines Logo
12:28 pm - 11:55 pmSNA-ECP
9h 27m2 stops
$502American Airlines
Find Deal
Tue, Dec 23 - Tue, Jan 6
Southwest Logo
1:30 pm - 7:20 pmECP-SNA
7h 50m1 stop
Southwest Logo
6:40 pm - 9:45 amSNA-ECP
13h 05m2 stops
$512Southwest
Find Deal
Tue, Dec 23 - Tue, Jan 6
United Airlines Logo
2:55 pm - 9:55 pmECP-SNA
9h 00m1 stop
United Airlines Logo
8:00 am - 4:12 pmSNA-ECP
6h 12m1 stop
$522United Airlines
Find Deal
Thu, Dec 11 - Sun, Dec 14
American Airlines Logo
6:30 am - 3:23 pmECP-SNA
10h 53m2 stops
American Airlines Logo
9:30 am - 11:55 pmSNA-ECP
12h 25m2 stops
$537American Airlines
Find Deal
Tue, Dec 23 - Tue, Jan 6
American Airlines Logo
6:46 am - 8:13 pmECP-SNA
15h 27m1 stop
American Airlines Logo
12:52 pm - 9:19 pmSNA-ECP
6h 27m1 stop
$611American Airlines
Find Deal
Tue, Dec 23 - Sat, Dec 27
Southwest Logo
3:30 pm - 9:40 pmECP-SNA
8h 10m2 stops
Southwest Logo
11:55 am - 10:35 pmSNA-ECP
8h 40m2 stops
$627Southwest
Find Deal
Tue, Dec 23 - Sat, Dec 27
Southwest Logo
1:30 pm - 7:20 pmECP-SNA
7h 50m1 stop
Southwest Logo
11:55 am - 10:35 pmSNA-ECP
8h 40m2 stops
$652Southwest
Find Deal
Tue, Dec 23 - Sat, Dec 27
American Airlines Logo
12:40 pm - 5:58 pmECP-SNA
7h 18m1 stop
American Airlines Logo
6:48 pm - 12:10 pmSNA-ECP
15h 22m1 stop
$710American Airlines
Find Deal
Booking Insights

KAYAK's insights & trends for Panama City to Santa Ana flights

Get data-powered insights and trends into flights from Panama City to Santa Ana to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Panama City to John Wayne (Santa Ana)?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Panama City to John Wayne (Santa Ana) were found on Southwest ($487) and American Airlines ($497).

Which airlines fly non-stop between Panama City and Santa Ana?

Airline and price data is aggregated from results in KAYAK’s search results from the last 2 weeks for round-trip flights from Panama City to Santa Ana.

There is just one airline that flies from Panama City to Santa Ana direct and that is American Airlines. The best round-trip deal found from American Airlines for the route is $339.

Good to know

Low seasonJuly
Cheapest flight$219
Best time to beat the crowds with an average 23% drop in price.
Most popular time to fly and prices are also 19% lower on average.
Flight from Panama City to John Wayne (Santa Ana)

When to book flights from Panama City to Santa Ana

Are your dates flexible? Find out the best times to travel from Panama City to Santa Ana based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Panama City to John Wayne (Santa Ana)

  • What is the cheapest flight from Panama City to Santa Ana?

    In the last 3 days, the lowest price for a flight from Panama City to Santa Ana was $219 for a one-way ticket and $487 for a round-trip.

  • Do I need a passport to fly between Panama City and John Wayne (Santa Ana)?

    Even though you are not required to have a passport, keep in mind that an official ID is needed to board the airplane.

  • Which airports will I be using when flying from Panama City to John Wayne (Santa Ana)?

    When flying out of Panama City you will be using Panama City NW Florida Beaches. You will be landing at John Wayne (Santa Ana), also known as Santa Ana J. Wayne/Orange Cnty.

  • Which aircraft models fly most regularly from Panama City to John Wayne (Santa Ana)?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Panama City to John Wayne (Santa Ana)?

    oneworld is the only airline alliance operating flights between Panama City and John Wayne (Santa Ana).

  • How does KAYAK find such low prices on flights from Panama City to John Wayne (Santa Ana)?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Panama City to John Wayne (Santa Ana).

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Panama City to John Wayne (Santa Ana)?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to John Wayne (Santa Ana) from Panama City is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Panama City to John Wayne (Santa Ana)?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to John Wayne (Santa Ana) with an airline and back to Panama City with another airline. Booking your flights between Panama City and SNA can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Panama City to John Wayne (Santa Ana)?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to John Wayne (Santa Ana) from Panama City up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Panama City to Santa Ana

 
See real verified KAYAK customer reviews for airlines flying from Panama City to Santa Ana. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Panama City to Santa Ana? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.2
American AirlinesOverall score based on 11050 reviews
7.2Comfort
8.0Crew
7.5Boarding
6.9Entertainment
6.4Food
Airline reviews

The experience with American Airlines was good, although the Philippines Airlines flight was much better (better seats, better food, better entertainment options, overall better). Again, the MIA to LAX flight was fine, but nothing in comparison to the comfort and accommodations of the Philippines Airlines flight from LAX to MNL.

10.0 ExcellentAnonymous, Nov 2025MIA - LAX
Read more American Airlines reviews

The experience with American Airlines was good, although the Philippines Airlines flight was much better (better seats, better food, better entertainment options, overall better). Again, the MIA to LAX flight was fine, but nothing in comparison to the comfort and accommodations of the Philippines Airlines flight from LAX to MNL.

Loved the crew . Absolutely no complaints. Except for luggage lost

Wish some foods provided rather than just biscuit/cookie for flight more than 2 hours

We are too tired and frustrated to comment politely at this point

The flight crew was rude. We were in first class and no one even offered water until an hour after we were in the air. Horrible experience

Great. Quick and quiet and east. The breakfast choices were a welcome surprise!

The stewardess hit me with the food kart twice on the head and didn't say I'm sorry once. The same stewardess gave me a warm Apple Juice with No ice. The Flight was delayed for Departure 6 times, starting from 2:36pm, finally taking off 7:50pm. I was late picking up my child from the sitter by 3 hours.

Did not get the seat I selected and paid for.

My flight was delayed for several hours. Sitting at gate 16 for several hours, I got a text from Kayak the gate changed to 9 before it was announced. Very bad communication at each gate from American Airlines employees. I received 10 notifications of delay from Kayak. My vacation started off horrible! I will write to American Airlines corporate office also.

Delayed flight that lead to a missed connection and a 5-hour trip became a 12-hour flight 🙄

Everything you need to know for your flight from Panama City to Santa Ana

Information on your arrival and departure airports