ECP - SNA

$160 Find Cheap Flights from Panama City to Santa Ana

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Panama City to Santa Ana departing on 10/27. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

KAYAK searches hundreds of travel sites at once for deals on flights to Santa Ana

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to Santa Ana, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to Santa Ana, as well as popular online travel agencies
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Flight Deals

Cheap Flights from Panama City to Santa Ana (ECP-SNA)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Panama City to Santa Ana that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Panama City to Santa Ana

Tue, Nov 11 - Thu, Nov 13
United Airlines Logo
6:30 am - 2:07 pmECP-SNA
9h 37m1 stop
United Airlines Logo
7:34 pm - 9:19 amSNA-ECP
11h 45m2 stops
$304United Airlines
Find Deal
Tue, Nov 11 - Thu, Nov 13
United Airlines Logo
6:30 am - 2:58 pmECP-SNA
10h 28m2 stops
United Airlines Logo
7:34 pm - 9:19 amSNA-ECP
11h 45m2 stops
$309United Airlines
Find Deal
Wed, Jan 21 - Mon, Feb 9
Delta Logo
7:45 am - 6:17 pmECP-SNA
12h 32m2 stops
Delta Logo
9:20 pm - 8:20 amSNA-ECP
9h 00m1 stop
$324Delta
Find Deal
Thu, Jan 22 - Sat, Feb 7
American Airlines Logo
7:02 am - 2:09 pmECP-SNA
9h 07m1 stop
American Airlines Logo
10:53 am - 9:19 pmSNA-ECP
8h 26m1 stop
$338American Airlines
Find Deal
Thu, Jan 22 - Sat, Feb 7
United Airlines Logo
4:54 pm - 9:52 pmECP-SNA
6h 58m1 stop
United Airlines Logo
7:50 pm - 12:02 pmSNA-ECP
14h 12m2 stops
$343United Airlines
Find Deal
Tue, Nov 11 - Thu, Nov 13
Delta Logo
5:00 pm - 10:19 pmECP-SNA
7h 19m1 stop
Delta Logo
12:45 pm - 11:07 pmSNA-ECP
8h 22m1 stop
$357Delta
Find Deal
Wed, Jan 21 - Fri, Feb 6
Delta Logo
7:45 am - 6:17 pmECP-SNA
12h 32m2 stops
Delta Logo
9:20 pm - 8:20 amSNA-ECP
9h 00m1 stop
$362Delta
Find Deal
Thu, Dec 11 - Sun, Dec 14
American Airlines Logo
2:43 pm - 8:48 pmECP-SNA
8h 05m1 stop
American Airlines Logo
12:43 pm - 9:16 pmSNA-ECP
6h 33m1 stop
$403American Airlines
Find Deal
Wed, Dec 24 - Thu, Jan 1
Southwest Logo
10:00 am - 6:35 pmECP-SNA
10h 35m2 stops
Southwest Logo
7:30 am - 7:05 pmSNA-ECP
9h 35m2 stops
$467Southwest
Find Deal
Fri, Nov 21 - Fri, Nov 28
Southwest Logo
7:30 am - 1:05 pmECP-SNA
7h 35m1 stop
Southwest Logo
8:55 am - 9:05 pmSNA-ECP
10h 10m2 stops
$504Southwest
Find Deal

Everything you should know

Top airlines
United Airlines
Cheapest • from $304 (round-trip)
American Airlines
Best reviews • 7.2 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Cheapest round-trip
$304
United Airlines
Tue 11/11Thu 11/13
ECP - SNA • 1 stop
Cheapest one-way
$160
Overall average: $404
United Airlines
Mon 10/27
ECP - SNA • 1 stop
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Santa Ana!
Booking Insights

KAYAK's insights & trends for Panama City to Santa Ana flights

Get data-powered insights and trends into flights from Panama City to Santa Ana to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Panama City to John Wayne (Santa Ana)?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Panama City to John Wayne (Santa Ana) were found on United Airlines ($304) and Delta ($324).

Which airlines fly non-stop between Panama City and Santa Ana?

Airline and price data is aggregated from results in KAYAK’s search results from the last 2 weeks for round-trip flights from Panama City to Santa Ana.

There is just one airline that flies from Panama City to Santa Ana direct and that is American Airlines. The best round-trip deal found from American Airlines for the route is $339.

Good to know

Cheapest flight$160
Most popular time to fly and prices are also 30% lower on average.
Flight from Panama City to John Wayne (Santa Ana)

When to book flights from Panama City to Santa Ana

Are your dates flexible? Find out the best times to travel from Panama City to Santa Ana based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Panama City to John Wayne (Santa Ana)

  • What is the cheapest flight from Panama City to Santa Ana?

    In the last 3 days, the lowest price for a flight from Panama City to Santa Ana was $160 for a one-way ticket and $304 for a round-trip.

  • Do I need a passport to fly between Panama City and John Wayne (Santa Ana)?

    Even though you are not required to have a passport, keep in mind that an official ID is needed to board the airplane.

  • Which airports will I be using when flying from Panama City to John Wayne (Santa Ana)?

    When flying out of Panama City you will be using Panama City NW Florida Beaches. You will be landing at John Wayne (Santa Ana), also known as Santa Ana J. Wayne/Orange Cnty.

  • Which aircraft models fly most regularly from Panama City to John Wayne (Santa Ana)?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Panama City to John Wayne (Santa Ana)?

    oneworld is the only airline alliance operating flights between Panama City and John Wayne (Santa Ana).

  • How does KAYAK find such low prices on flights from Panama City to John Wayne (Santa Ana)?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Panama City to John Wayne (Santa Ana).

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Panama City to John Wayne (Santa Ana)?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to John Wayne (Santa Ana) from Panama City is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Panama City to John Wayne (Santa Ana)?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to John Wayne (Santa Ana) with an airline and back to Panama City with another airline. Booking your flights between Panama City and SNA can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Panama City to John Wayne (Santa Ana)?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to John Wayne (Santa Ana) from Panama City up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Panama City to Santa Ana

 
See real verified KAYAK customer reviews for airlines flying from Panama City to Santa Ana. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Panama City to Santa Ana? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.2
American AirlinesOverall score based on 11041 reviews
7.5Boarding
7.2Comfort
6.4Food
6.9Entertainment
8.0Crew
Airline reviews

The flight crew was rude. We were in first class and no one even offered water until an hour after we were in the air. Horrible experience

2.0 MediocreKelly, Sep 2025LIH - LAX
Read more American Airlines reviews

The flight crew was rude. We were in first class and no one even offered water until an hour after we were in the air. Horrible experience

Great. Quick and quiet and east. The breakfast choices were a welcome surprise!

The stewardess hit me with the food kart twice on the head and didn't say I'm sorry once. The same stewardess gave me a warm Apple Juice with No ice. The Flight was delayed for Departure 6 times, starting from 2:36pm, finally taking off 7:50pm. I was late picking up my child from the sitter by 3 hours.

Did not get the seat I selected and paid for.

My flight was delayed for several hours. Sitting at gate 16 for several hours, I got a text from Kayak the gate changed to 9 before it was announced. Very bad communication at each gate from American Airlines employees. I received 10 notifications of delay from Kayak. My vacation started off horrible! I will write to American Airlines corporate office also.

Delayed flight that lead to a missed connection and a 5-hour trip became a 12-hour flight 🙄

There is no room, no gluten free options, or any free internet/entertainment. You have to bring your own tablet or smartphone because there are no screens.

Amazing food, great staff, with one noticable detail missing ...but no seat entertainment in any of aircraft ...I am not a fan

Boarding gate in Honolulu was staffed with a great clerk with a soothing voice despite the flight delay of over an hour. Flight attendants in the plane were all grumpy, not pleasant looking bunch. Their sour attitude showed throughout the flight. Inly able to get a select few movies started. Most of the movie links in the “free entertainment” did not work.

This was a horrible experience. For a first class experience, my chair was held together by 3M tape - and I have a photo. The crew weren’t very attentive, somewhat dismissive and forgot my drink and snack, the chair reclined about 3 inches on a 6-hour cross country flight. I was also not informed that there was no lounge available in Newark airport because of renovations, so all around this was one of the worst experiences and I would actively avoid both American and Alaska Air going forward.

Everything you need to know for your flight from Panama City to Santa Ana

Information on your arrival and departure airports

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