ECP - SNA

$180 Find Cheap Flights from Panama City to Santa Ana

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Panama City to Santa Ana departing on 4/21. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Santa Ana

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to Santa Ana, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to Santa Ana, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$441
American Airlines
Wed 4/15Fri 5/1
ECP - SNA • 1 stop
Cheapest one-way
$180
United Airlines
Tue 4/21
ECP - SNA • 1 stop
Top airlines
American Airlines
Cheapest • from $441 (round-trip)
American Airlines
Best reviews • 7.2 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Santa Ana!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Panama City to Santa Ana (ECP-SNA)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Panama City to Santa Ana that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Panama City to Santa Ana

Wed, Apr 15 - Fri, May 1
American Airlines Logo
12:58 pm - 9:13 pm
ECP
-
SNA
10h 15m
1 stop
American Airlines Logo
7:20 pm - 10:03 am
SNA
-
ECP
12h 43m
2 stops
$441American Airlines
Thu, Aug 6 - Sun, Aug 9
Southwest Logo
11:20 am - 4:25 pm
ECP
-
SNA
7h 05m
1 stop
Southwest Logo
7:45 am - 6:15 pm
SNA
-
ECP
8h 30m
1 stop
$457Southwest
Thu, Aug 6 - Sun, Aug 9
Southwest Logo
11:20 am - 5:50 pm
ECP
-
SNA
8h 30m
2 stops
Southwest Logo
7:45 am - 6:15 pm
SNA
-
ECP
8h 30m
1 stop
$462Southwest
Thu, Aug 6 - Sun, Aug 9
Southwest Logo
6:00 am - 12:30 pm
ECP
-
SNA
8h 30m
2 stops
Southwest Logo
8:45 pm - 9:25 am
SNA
-
ECP
10h 40m
2 stops
$467Southwest
Thu, Apr 30 - Mon, May 4
United Airlines Logo
2:14 pm - 10:30 pm
ECP
-
SNA
10h 16m
1 stop
United Airlines Logo
6:39 pm - 9:47 am
SNA
-
ECP
13h 08m
2 stops
$480United Airlines
Wed, Apr 15 - Fri, May 1
Southwest Logo
12:05 pm - 7:05 pm
ECP
-
SNA
9h 00m
2 stops
Southwest Logo
9:10 pm - 9:00 am
SNA
-
ECP
9h 50m
2 stops
$481Southwest
Wed, Apr 15 - Fri, May 1
Southwest Logo
3:00 pm - 9:50 pm
ECP
-
SNA
8h 50m
1 stop
Southwest Logo
10:30 am - 9:30 pm
SNA
-
ECP
9h 00m
1 stop
$488Southwest
Thu, Feb 26 - Mon, Mar 2
United Airlines Logo
5:00 pm - 9:45 pm
ECP
-
SNA
6h 45m
1 stop
United Airlines Logo
12:23 pm - 9:56 pm
SNA
-
ECP
7h 33m
1 stop
$557United Airlines
Thu, Feb 26 - Mon, Mar 2
United Airlines Logo
5:00 pm - 9:45 pm
ECP
-
SNA
6h 45m
1 stop
United Airlines Logo
7:01 am - 9:56 pm
SNA
-
ECP
12h 55m
2 stops
$562United Airlines
Thu, Feb 26 - Mon, Mar 2
Southwest Logo
3:35 pm - 10:25 pm
ECP
-
SNA
8h 50m
2 stops
Southwest Logo
7:30 am - 6:45 pm
SNA
-
ECP
9h 15m
2 stops
$567Southwest
Booking Insights

KAYAK's insights & trends for Panama City to Santa Ana flights

Get data-powered insights and trends into flights from Panama City to Santa Ana to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Panama City to John Wayne (Santa Ana)?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Panama City to John Wayne (Santa Ana) were found on American Airlines ($441) and Southwest ($457).

Find deals

Good to know

Low seasonJuly
Cheapest flight$180
Best time to beat the crowds with an average 15% drop in price.
Most popular time to fly and prices are also 2% lower on average.
Flight from Panama City to John Wayne (Santa Ana)

When to book flights from Panama City to Santa Ana

Are your dates flexible? Find out the best times to travel from Panama City to Santa Ana based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Panama City to John Wayne (Santa Ana)

  • What is the cheapest flight from Panama City to Santa Ana?

    In the last 3 days, the lowest price for a flight from Panama City to Santa Ana was $180 for a one-way ticket and $441 for a round-trip.

  • Do I need a passport to fly between Panama City and John Wayne (Santa Ana)?

    Even though you are not required to have a passport, keep in mind that an official ID is needed to board the airplane.

  • Which airports will I be using when flying from Panama City to John Wayne (Santa Ana)?

    When flying out of Panama City you will be using Panama City NW Florida Beaches. You will be landing at John Wayne (Santa Ana), also known as Santa Ana J. Wayne/Orange Cnty.

  • Which aircraft models fly most regularly from Panama City to John Wayne (Santa Ana)?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Panama City to John Wayne (Santa Ana)?

    oneworld is the only airline alliance operating flights between Panama City and John Wayne (Santa Ana).

  • How does KAYAK find such low prices on flights from Panama City to John Wayne (Santa Ana)?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Panama City to John Wayne (Santa Ana).

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Panama City to John Wayne (Santa Ana)?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to John Wayne (Santa Ana) from Panama City is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Panama City to John Wayne (Santa Ana)?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to John Wayne (Santa Ana) with an airline and back to Panama City with another airline. Booking your flights between Panama City and SNA can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Panama City to John Wayne (Santa Ana)?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to John Wayne (Santa Ana) from Panama City up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Panama City to Santa Ana

 
See real verified KAYAK customer reviews for airlines flying from Panama City to Santa Ana. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Panama City to Santa Ana? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.2
American AirlinesOverall score based on 11297 reviews
7.5Boarding
7.2Comfort
6.4Food
6.9Entertainment
8.0Crew
Airline reviews

The flight was significantly delayed for 6.5 hours because of snow. There was no communication once the plane returned to the gate regarding when the flight would resume. Other flights were departing while our flight was being unloaded for reasons unknown. Our flight also seemed out of the queue regarding further deicing, refueling, and waiting to Taxi to the runway.

2.0 MediocreAlan, Feb 2026
BOS - LAX
Read more American Airlines reviews

The flight was significantly delayed for 6.5 hours because of snow. There was no communication once the plane returned to the gate regarding when the flight would resume. Other flights were departing while our flight was being unloaded for reasons unknown. Our flight also seemed out of the queue regarding further deicing, refueling, and waiting to Taxi to the runway.

They are always late and seats was also not having working charger

did not have enough meal for first class passengers so offer us snack

Amazing I love American. I’ll never fly anyone else if I can help it.

Everything about the flight was lovely. My only suggestion would be to offer a few more options of tv series from Apple TV or HBO.

After the door had been closed, the cockpit makes an announcement that catering is running late and it is not the airline's fault. It is their fault in the sense that we had to sit for 2 hours or more when we could have stayed in the terminal. Poor communications between catering and airline. This caused a young man to lose his temper and he went storming out hitting objects. He had complained to the gate agent that he had already waited at the gate 7 hours and when can the airplane leave? Airilnes do a poor job of explaining delays, maintenance issues, etc. whereas being truthful may gain more sympathy or understanding.

Experience was good, however I had a delay due to weather happening and had to re purchase a seat on a new plane for a higher price (could be my own issue and misunderstanding) but other than that situation. First time flyer (by myself) was terrific!! The last from ORD to ALO didn't have wifi, but it was only 45 minutes so I'm sure that was part of the reason. Overall my experience was great! Next time I will remember to buy tickets with longer layovers. The delays really saved my overall anxiety. :)

We were told the flight was delayed 5 times, then it was moved to the next day.

The experience with American Airlines was good, although the Philippines Airlines flight was much better (better seats, better food, better entertainment options, overall better). Again, the MIA to LAX flight was fine, but nothing in comparison to the comfort and accommodations of the Philippines Airlines flight from LAX to MNL.

Loved the crew . Absolutely no complaints. Except for luggage lost

Everything you need to know for your flight from Panama City to Santa Ana

Information on your arrival and departure airports

Panama City (ECP)
Santa Ana (SNA)