SNA - ECP

$309 Find Cheap Flights from Santa Ana to Panama City

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Santa Ana to Panama City departing on 11/28. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

KAYAK searches hundreds of travel sites at once for deals on flights to Panama City

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santa Ana to Panama City, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santa Ana to Panama City, as well as popular online travel agencies
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Flight Deals

Cheap Flights from Santa Ana to Panama City (SNA-ECP)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Santa Ana to Panama City that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Santa Ana to Panama City

Fri, Nov 14 - Mon, Nov 17
Delta Logo
12:45 pm - 11:07 pmSNA-ECP
8h 22m1 stop
Delta Logo
4:26 pm - 10:19 pmECP-SNA
7h 53m1 stop
$357Delta
Find Deal
Fri, Nov 14 - Mon, Nov 17
Delta Logo
5:20 pm - 8:35 amSNA-ECP
13h 15m2 stops
Delta Logo
4:26 pm - 10:19 pmECP-SNA
7h 53m1 stop
$362Delta
Find Deal
Fri, Nov 14 - Mon, Nov 17
American Airlines Logo
9:59 am - 11:15 pmSNA-ECP
11h 16m2 stops
American Airlines Logo
1:11 pm - 9:53 pmECP-SNA
10h 42m2 stops
$387American Airlines
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Thu, Nov 6 - Tue, Nov 11
United Airlines Logo
12:14 pm - 9:49 pmSNA-ECP
7h 35m1 stop
United Airlines Logo
5:00 pm - 9:54 pmECP-SNA
6h 54m1 stop
$432United Airlines
Find Deal
Thu, Nov 6 - Tue, Nov 11
United Airlines Logo
12:14 pm - 9:49 pmSNA-ECP
7h 35m1 stop
United Airlines Logo
6:30 am - 2:58 pmECP-SNA
10h 28m2 stops
$437United Airlines
Find Deal
Fri, Nov 14 - Mon, Nov 17
Delta Logo
5:20 pm - 8:35 amSNA-ECP
13h 15m2 stops
Delta Logo
6:00 am - 4:24 pmECP-SNA
12h 24m2 stops
$447Delta
Find Deal
Thu, Nov 6 - Tue, Nov 11
United Airlines Logo
7:34 pm - 9:19 amSNA-ECP
11h 45m2 stops
United Airlines Logo
6:30 am - 2:58 pmECP-SNA
10h 28m2 stops
$477United Airlines
Find Deal
Fri, Oct 17 - Tue, Oct 21
American Airlines Logo
12:43 pm - 9:34 pmSNA-ECP
6h 51m1 stop
American Airlines Logo
6:31 am - 11:52 amECP-SNA
7h 21m1 stop
$537American Airlines
Find Deal
Fri, Oct 17 - Tue, Oct 21
Delta Logo
7:00 pm - 8:44 amSNA-ECP
11h 44m2 stops
Delta Logo
5:32 pm - 10:28 pmECP-SNA
6h 56m1 stop
$542Delta
Find Deal
Wed, Oct 22 - Sun, Oct 26
United Airlines Logo
6:50 am - 9:48 pmSNA-ECP
12h 58m2 stops
United Airlines Logo
6:30 am - 11:12 amECP-SNA
6h 42m1 stop
$799United Airlines
Find Deal

Everything you should know

Top airlines
Delta
Cheapest • from $357 (round-trip)
Southwest
Best reviews • 8.0 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Cheapest round-trip
$357
Delta
Fri 11/14Mon 11/17
SNA - ECP • 1 stop
Cheapest one-way
$309
Typical prices: $249-272
Delta
Fri 11/28
SNA - ECP • 1 stop
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Panama City!
Booking Insights

KAYAK's insights & trends for Santa Ana to Panama City flights

Get data-powered insights and trends into flights from Santa Ana to Panama City to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from John Wayne (Santa Ana) to Panama City?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from John Wayne (Santa Ana) to Panama City were found on Delta ($357) and American Airlines ($387).

Which airlines fly non-stop between Santa Ana and Panama City?

Airline and price data is aggregated from results in KAYAK’s search results from the last 2 weeks for round-trip flights from Santa Ana to Panama City.

There are 3 airlines that fly nonstop from Santa Ana to Panama City. They are: American Airlines, Southwest and United Airlines. The cheapest price of all airlines flying this route was found with Southwest at $341 for a round-trip flight. On average, the best prices for this route can be found at United Airlines.

Good to know

Low seasonAugust
Cheapest flight$309
Best time to beat the crowds with an average 27% drop in price.
Most popular time to fly with an average 3% increase in price.
Flight from John Wayne (Santa Ana) to Panama City

When to book flights from Santa Ana to Panama City

Are your dates flexible? Find out the best times to travel from Santa Ana to Panama City based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from John Wayne (Santa Ana) to Panama City

  • What is the cheapest flight from Santa Ana to Panama City?

    In the last 3 days, the lowest price for a flight from Santa Ana to Panama City was $309 for a one-way ticket and $357 for a round-trip.

  • Do I need a passport to fly between John Wayne (Santa Ana) and Panama City?

    Even though you are not required to have a passport, keep in mind that an official ID is needed to board the airplane.

  • Which aircraft models fly most regularly from John Wayne (Santa Ana) to Panama City?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from John Wayne (Santa Ana) to Panama City?

    Star Alliance, and oneworld are the airline alliances operating flights between John Wayne (Santa Ana) and Panama City, with Star Alliance being the most commonly used for this route.

  • Which is the best airline for flights from Santa Ana to Panama City, Southwest or United Airlines?

    The two airlines most popular with KAYAK users for flights from Santa Ana to Panama City are Southwest and United Airlines. With an average price for the route of $582 and an overall rating of 8.0, Southwest is the most popular choice. United Airlines is also a great choice for the route, with an average price of $446 and an overall rating of 7.4.

  • How does KAYAK find such low prices on flights from John Wayne (Santa Ana) to Panama City?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from John Wayne (Santa Ana) to Panama City.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from John Wayne (Santa Ana) to Panama City?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Panama City from John Wayne (Santa Ana) is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from John Wayne (Santa Ana) to Panama City?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Panama City with an airline and back to John Wayne (Santa Ana) with another airline. Booking your flights between John Wayne (Santa Ana) and ECP can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from John Wayne (Santa Ana) to Panama City?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Panama City from John Wayne (Santa Ana) up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 3 airlines serving from Santa Ana to Panama City

 
See real verified KAYAK customer reviews for airlines flying from Santa Ana to Panama City. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Santa Ana to Panama City? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
SouthwestOverall score based on 4248 reviews
8.1Boarding
7.5Entertainment
7.0Food
8.0Comfort
8.6Crew
Airline reviews

As always, the entire Southwest experience was wonderful, from online booking to flight to baggage retrieval. Very grateful.

10.0 ExcellentRobert, Sep 2025SFO - LAS
Read more Southwest reviews

As always, the entire Southwest experience was wonderful, from online booking to flight to baggage retrieval. Very grateful.

The weather could have been better. There was a 40 minute ATC delay in SFO because of marine fog and a micro cell storm delayed landing and take-off at Nashville. The gate was changed 5 minutes from boarding from gate B3 to gate C23 at Nashville airport.

The cabin was quiet for the redeye flight. The area was clean. The staff was great. The 787 Max was in good condition. Drawbacks were that the seat widths were tight for some passengers. The seat padding was at best average and for a long flight uncomfortable.

The quality of Southwest Airlines continues to degrade each time I fly with them. If it were not for the free luggage, I would probably choose another airline. Their prices are a little bit competitive, but way too high for the quality of the service. Southwest is not unique in this way. Domestic flight in the United States of America has continued to be a lower and lower quality product. Very sad when you compare the quality of domestic airlines to that of many international airlines around the world.

Delayed flight. Nicest crew member was a SW pilot flying seated next to me who kindly move to seat the final passenger. Flight extra delayed. My cup of refreshment of ginger ale was so packed with ice it was literally 2 sips.

No trays in our seats, we sat in first row, purchased a business class fare. Had to hold our drinks and snack in our hands. No plugs for our cell phones. Had to pay for it a drink cocktail each. Seats so uncomfortable.

Flight wasn’t even full, but too many carry-ons caused us to run out of bin space. New bag fee has folks who would usually check their bags carrying on. Watching Southwest morph into Spirit/Frontier is so sad to watch

Southwest is Southwest. No frills. If you're luck enough to get a happy crew (we did), then it makes for a nicer flight.

I'm not a fan of Southwest's model. I don't like the herding style of boarding.

It is southwest seat was ok. Not the most comfortable seat

I was in first class. The outlets at my seat did not work. The plane was shabby and run down. I had prepurchsed a day subscription for internet that was not redeemable. I had to repurchase the internet for my flight and then it didn’t work anyway. Quite disappointed in what was supposed to be the launch of a great vacation.

The newer screen was super cool and had the option to watch many different shows or movies. Crew was polite and helpful. However again, many children screaming bloody murder and kicking my seat, and parents doing nothing about it as usual.

I understand stuff happens, but plane failures are likely due to lack of maintenance. Additionally, air conditioning wasn't working, no snack/drink service, no WiFi. Fortunately, the crew was communicative and light-hearted. United grabbed another plane and we were able to get to our destination.

Stuck on tarmac for two hours plus a 5.5 hour flight. Rude flight attendant. And no meals, not even for purchase!

I learned that seating towards the end of plane that a line forms for the restroom and people use your chair as a hand railing, bumping your seat consistently. I was seated in the aisle. I think that next time if I am towards the back row I would want to sit in the middle or window seat.

United sent me a mileage plus number last year but that number is invalid so I can’t use it to check into flights or collect mileage. There is human to speak about the problem, only computers who keep asking me if I am using the correct email. It’s so frustrating and I cannot resolve it.

Not a great experience. We paid for the upgrade for premium economy seats and seated ourselves in very comfortable seats. Someone came along with the same seat on their boarding pass. The aircraft had been changed and as a result we were booted out and sent further back to small uncomfortable seats. After complaining we were moved to emergency row seats, which gave us more leg room but the seats don’t recline. For people in our 70’s we found having to sit upright from California to NJ very uncomfortable. Not sure why they chose to move senior citizens instead of the two people that were allowed to take the more comfortable seats. Not happy.

I liked the choice of lemon ginger tea. I think stewardesses can be more considerate of older people needs.

Everything was great. Only thing that could’ve made it better was buy on board options for hot food, but the snacks were decent. The flight attendants were great. I had no complaints. I was able to make it to my destination safely

Boarded plane and then delayed 1.5 hours while on the plane

It was a red eye flight, so no meals were provided, but it was fine with snacks. The seats felt cramped and almost too narrow.

We didn't take off until an hour after we boarded.

Wish they had the seat-back video screens for watching movies or playing games.

Very good but wish they had the seat-back video screens for movies & games

Flight was delayed not sure why no explanation given and no apologies either. Otherwise the flight was fine

While waiting to claim my checked luggage, I discovered the airline had lost it. After a long wait and inquiries, I discovered it was on another flight. Fortunately, the airline finally sent my luggage home.

Our flight was 1.5 hours delayed. There was no weather for the inbound flight, so I don't understand why. This meant a VERY late arrival and only a quick nap before my morning flight.

Flight delays numerous times. Everytime we would get close to boarding it would be delayed again. Strung along the entire time.

This flight never occurred because AA couldn’t get their act together.

During service there was a garbage/beverage spill near our seats that never was cleaned up. On a relatively short flight when we’re fortunate enough to actually have in flight movies available, the flight attendants pitching the AADVANTAGE credit card shouldn’t talk for the last 10 minutes of the flight so that we miss the end of the movie.

Everything you need to know for your flight from Santa Ana to Panama City

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