$317 Find Cheap Flights from Panama City to Missouri

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Panama City to Missouri departing on 1/22. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Missouri

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to Missouri, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to Missouri, as well as popular online travel agencies
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Flight Deals

Cheap Flights from Panama City to Missouri

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
St. Louis
St. Louis1 stop$516
Kansas City
Kansas City2 stops$432
Springfield
Springfield1 stop$612
St. Louis
St. Louis1 stop$516
Kansas City
Kansas City2 stops$432
Springfield
Springfield1 stop$612

Book Cheap Panama City to Missouri Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Panama City to Missouri that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Panama City to Missouri

Fri, Feb 13 - Wed, Feb 18
American Airlines Logo
4:05 pm - 12:21 pm
PTY
-
MCI
21h 16m2 stops
American Airlines Logo
5:12 pm - 1:50 pm
MCI
-
PTY
19h 38m2 stops
$432American Airlines
Fri, Feb 13 - Wed, Feb 18
United Airlines Logo
4:41 pm - 4:38 pm
PTY
-
MCI
24h 57m1 stop
United Airlines Logo
8:00 am - 5:07 pm
MCI
-
PTY
8h 07m1 stop
$438United Airlines
Thu, Jan 22 - Mon, Jan 26
United Airlines Logo
4:41 pm - 9:31 am
PTY
-
MCI
17h 50m1 stop
United Airlines Logo
10:30 am - 7:38 pm
MCI
-
PTY
8h 08m1 stop
$458United Airlines
Thu, Jan 22 - Mon, Jan 26
United Airlines Logo
4:41 pm - 9:31 am
PTY
-
MCI
17h 50m1 stop
United Airlines Logo
6:30 pm - 5:07 pm
MCI
-
PTY
21h 37m2 stops
$463United Airlines
Sat, Jan 17 - Wed, Jan 21
United Airlines Logo
4:41 pm - 10:32 am
PTY
-
MCI
18h 51m2 stops
United Airlines Logo
8:05 am - 7:38 pm
MCI
-
PTY
10h 33m1 stop
$482United Airlines
Mon, Jan 19 - Fri, Jan 23
American Airlines Logo
2:27 pm - 11:04 am
PTY
-
MCI
21h 37m1 stop
American Airlines Logo
11:44 am - 3:52 pm
MCI
-
PTY
27h 08m1 stop
$495American Airlines
Mon, Jan 19 - Fri, Jan 23
American Airlines Logo
2:27 pm - 11:04 am
PTY
-
MCI
21h 37m1 stop
American Airlines Logo
5:49 pm - 1:27 pm
MCI
-
PTY
18h 38m2 stops
$499American Airlines
Tue, Feb 17 - Tue, Feb 24
United Airlines Logo
8:55 am - 10:14 pm
PTY
-
STL
14h 19m1 stop
United Airlines Logo
6:25 am - 8:02 pm
STL
-
PTY
12h 37m2 stops
$516United Airlines
Sat, Jan 17 - Wed, Jan 21
United Airlines Logo
4:41 pm - 9:31 am
PTY
-
MCI
17h 50m1 stop
United Airlines Logo
8:00 am - 7:38 pm
MCI
-
PTY
10h 38m2 stops
$533United Airlines
Thu, Feb 19 - Wed, Feb 25
Multiple Airlines Logo
2:55 am - 12:27 am
PTY
-
STL
22h 32m2 stops
Multiple Airlines Logo
8:17 pm - 8:34 pm
STL
-
PTY
23h 17m1 stop
$560Multiple Airlines
Booking Insights

KAYAK's insights & trends for Panama City to Missouri flights

Get data-powered insights and trends into flights from Panama City to Missouri to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Panama City to Missouri?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Panama City to Missouri, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Panama City to Missouri is June, when tickets cost $362 (return) on average. On the other hand, the most expensive months are July and August, when the average cost of round-trip tickets is $659 and $628 respectively.

What’s the cheapest day of the week to fly from Panama City to Missouri?

The average price of all round-trip flights from Panama City to Missouri clicked on KAYAK for each day over the last 12 months.

If you are looking for a flight deal from Panama City to Missouri, look for departures on Thursdays and avoid leaving on a Wednesday, as it's usually the priciest day. When flying back from Missouri, Tuesday is the cheapest day to fly and Sunday is the most expensive.

Good to know

Low seasonMarch
Cheapest flight$317
Best time to beat the crowds with an average 12% drop in price.
Most popular time to fly and prices are also 16% lower on average.
Flight from Panama City to St. Louis

FAQs - booking Missouri flights

  • How does KAYAK find such low prices on flights from Panama City to Missouri?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Panama City to Missouri.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Panama City to Missouri?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Panama City to Missouri is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Panama City to Missouri?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Panama City to Missouri with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Panama City to Missouri?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Panama City to Missouri up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to Missouri?

    The cheapest time of day to fly to Missouri is generally in the afternoon, when round-trip flights cost $535 on average. Morning departures are around 1% more expensive than evening flights, on average. The most expensive time of day to fly to Missouri is generally in the morning, which is peak travel time and where the average cost of a ticket is $574.

Reviews of the top airlines flying from Panama City to Missouri

 
See real verified KAYAK customer reviews for airlines flying from Panama City to Missouri. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Panama City to Missouri? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
United AirlinesOverall score based on 9092 reviews
7.1Entertainment
7.3Comfort
7.7Boarding
6.6Food
8.1Crew
Airline reviews

The flight was on time. I generally don’t drink or eat on short flights and the seats were good and the flight attendants were friendly. That’s all I expect

10.0 ExcellentRoger, Dec 2025
CAE - ORD
Read more United Airlines reviews

The flight was on time. I generally don’t drink or eat on short flights and the seats were good and the flight attendants were friendly. That’s all I expect

Movie selection is good. Crew did not understand mileage program and were no help. Sick later. Food?

Staff on board was excellent. Positive upbeat helpful- like it used to be.

It was nice to have gotten up upgraded to first class with a meal on a three hour flight

For an expensive flight to another country, United has a lot of nerve serving pretzels and no meals (unless, of course, you want to buy something to eat). Unacceptable.

The food is terrible. The same pasta or chicken with bad taste and presentation

United have really come back. Airport and boarding process is clear and good, app and information also very good

The Sears in the 800s are not too good perfect Airbus why cant the new 737 fix that

Flight was delayed 8 times. We were sitting at the airport for 14 hours. We got 2 hours of sleep (if that) on what was not meant to be a red-eye.

It was probably one of the worst flights I’ve been on. The restrooms were never cleaned or stocked. The food was very subpar, and i usually enjoy airline food, so I was disappointed. It was just all around a bad experience. The only saving grace was the flight attendants.

Did not understand a single word the attendant said on the pa system. I was glad it was not an emergency.

Gate was overcrowded. Gate agents performed very well. Flight crew was top notch! Efficient & professional & courteous. Both meals not thermalized well. Dinner main dish was actually cold in the center. Almost inedible. Breakfast sandwich was lukewarm.

The boarding was as always, the crew tried their best but not enough. The food was a disaster I had dietary restrictions that were half met because the company did not loaded the food for the flight. The entertainment screen was fine but content was not and also they removed the free messaging option from the flight and they charged 30 dollars for that crappy bandwidth. This flight is not worth the cost and the company is going down on quality.

Awful. They won’t help me with anything. I booked on American but they abdicated to Iberia. The ticket was overpriced. Everything negative

it was fine, decent flight... dont get food besides cookies or pretzels so not sure why you ask about food. same for entertainment..

I got sick nothing contagious but distressing and the care I received by Kayla? Keighly the flight attendant will be memorable for ever. Thank You

I got sick nothing contagious but distressing enough and the care I received on the flight was astounding.

Waaay too small plane. They also need to up the size of the overhead bins. I would love to keep me 3k with of camera equipment in my hard case baggahe instead of it being thrown into the belly of the plane

Attendants were pleasant and the flight was smooth and relaxed.

A little late at the start but all worked out well.

Everything you need to know for your flight from Panama City to Missouri

Information on your arrival and departure airports