$432 Find Cheap Flights from Panama City to San Francisco - Compare and Save

Among airlines operating Panama City to San Francisco flights:

• Copa Airlines: offers extra legroom; offers free seat selection

Extra legroom and free seat selection availability depends on fare class and route.

Only Copa Airlines operates flights between Panama City and San Francisco.

Flights from Panama City to San Francisco usually depart from Panama City Tocumen Intl (PTY) and arrive at San Francisco (SFO).

Here are some options for this route, based on selected ticket types and cabin classes:

• Copa Airlines: a cabin bag and a checked bag in Economy Class

Bag allowance can vary by ticket type, cabin class, route and airline, so travelers should check the fare details before booking.

Only Economy Class is available on flights from Panama City to San Francisco.

On this route, layover flights are cheaper than nonstop options on average. Layover fares average $637 round-trip via San Salvador El Salvador Intl (SAL), compared to $766 for nonstop.

There is no standard. Checked-bag policies vary by airline on this route. Most carriers charge $100–$100 for the first checked bag in economy. Premium fares and elite-status bookings typically include a free checked bag.

The Boeing 737 MAX 9 family is used most often on this route, operated mainly by Copa Airlines and United Airlines. Other aircraft seen on the route include Boeing 737-900 variants.

One-stop flights from Panama City to San Francisco most commonly connect through:

• San Salvador El Salvador Intl (SAL) - 69% of one-stop connections
• Houston George Bush Intcntl (IAH) - 26% of one-stop connections
• Atlanta Hartsfield-Jackson (ATL) - 4% of one-stop connections
• San José del Cabo Los Cabos (SJD) - 1% of one-stop connections

San Salvador El Salvador Intl (SAL) handles the largest share of one-stop connections on this route.

Yes. Being flexible with your travel dates can save you up to 11% on the Panama City to San Francisco route. Thursday is the cheapest departure day at $703 round-trip on average, while Sunday is the most expensive at $783, a difference of $80. KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

Evening is the busiest departure period on Panama City to San Francisco flights, with 100% of flights leaving in that window. Morning departures account for 0%, afternoon flights for 0%, and night flights for 0%.

Some of the most popular sights in San Francisco are Fisherman's Wharf, Union Square and Moscone Center. These are among the most viewed places in San Francisco on KAYAK.

A nonstop flight from Panama City to San Francisco takes 7h 35m, covering 3,318 miles.

These are the earliest and latest flight times available from Panama City to San Francisco:

• Earliest: departs at 12:38 pm and lands at 8:13 pm
• Latest: departs at 6:31 pm and lands at 2:06 am.

The flight takes about 7h 35m.

Last-minute fares on this route - booked within 2 weeks of departure - run 14% above the route average of $753. Book 22 weeks before departure for the lowest fares.

Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.

Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $686 to $4,689. That means the highest observed fare was about 7x higher than the lowest one.

One-way fares from Panama City to San Francisco are currently higher than usual. Average one-way flight prices are about $638, which is 51% above the typical average for this route.

Flying via San Salvador El Salvador Intl (SAL) gives the shortest average 1-stop total travel time at 9h 40m, compared with 10h 06m via San José del Cabo Los Cabos (SJD) and 10h 38m via Houston George Bush Intcntl (IAH).

San Francisco is 2 hours behind Panama City (Pacific Time vs Eastern Time). Plan for the time shift when scheduling connections or first-day activities.

San Francisco Airport (SFO) hosts 5 major car rental companies, with daily rates starting from around $15 for economy cars. Top options include:
· Thrifty
· Europcar
· Dollar
· Hertz
· Fox

Round-trip flights from Panama City to San Francisco range from $665 to $827, with an average of $753 over the past 12 months. Anything below $665 counts as a good deal.