PTY - SFO

$308 Find Cheap Flights from Panama City to San Francisco - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Panama City to San Francisco departing on 8/20. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$635
Typical prices: $642-$774
Multiple Airlines
Wed 8/12Wed 8/19
PTY - SFO • 3 stops
Cheapest non-stop
$774
Typical prices: $642-$774
Copa Airlines
Thu 8/27Sun 8/30
PTY - SFO • Non-stop
Advice from real travelers
AI-powered summary based on content written by travel experts. AI can make mistakes.
United Priority Boarding helps secure bin space; Copa Showpass adds device entertainment.
At Panama City, expect secondary screening at the gate for U.S.-bound flights.
Expert advice
Expert advice
Expert advice
Expert advice
Top airlines
Cheapest • from $685 (round-trip)
Best reviews • 7.6 score
Airline reviews
Airline reviews
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Airline reviews
Airline reviews
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Nonstop flights
You can fly direct with Copa Airlines. Average duration is 7h 34m
Direct flights
Direct flights
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Direct flights
Direct flights
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Top layover airports
Cheapest • Avg $664 (round-trip)
Shortest trip • 9h 36m (one-way)
Insights
Insights
Insights
Insights
When to book
in advance
Our data shows that travelers who book at least 6 weeks in advance save around 22% compared to booking last minute.
Insights
Insights
Insights
Insights
When to travel
Cheapest • 14% price drop
Most popular
Good to know
Good to know
+1
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We hope you love your trip to San Francisco!
Flight Deals
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Expert advice
Flight Deals

Cheap Flights from Panama City to San Francisco (PTY-SFO)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Panama City to San Francisco that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Panama City to San Francisco

Wed, Aug 12 - Wed, Aug 19
Multiple Airlines Logo
5:30 am - 8:43 am
PTY
-
SFO
29h 13m
3 stops
Multiple Airlines Logo
5:35 pm - 12:35 am
SFO
-
PTY
29h 00m
3 stops
$635Multiple Airlines
Mon, Jul 20 - Wed, Jul 29
Avianca Logo
3:50 pm - 6:25 am
PTY
-
SFO
16h 35m
2 stops
Avianca Logo
11:55 pm - 5:00 pm
SFO
-
PTY
15h 05m
2 stops
$685Avianca
Mon, Jul 20 - Thu, Jul 30
Avianca Logo
3:50 pm - 6:25 am
PTY
-
SFO
16h 35m
2 stops
Avianca Logo
11:55 pm - 5:00 pm
SFO
-
PTY
15h 05m
2 stops
$686Avianca
Sun, Aug 16 - Sun, Aug 23
Avianca Logo
3:50 pm - 6:25 am
PTY
-
SFO
16h 35m
2 stops
Avianca Logo
11:55 pm - 10:30 am
SFO
-
PTY
8h 35m
1 stop
$691Avianca
Mon, Oct 12 - Sat, Oct 24
Avianca Logo
5:30 am - 12:50 pm
PTY
-
SFO
9h 20m
1 stop
Avianca Logo
2:15 pm - 10:30 am
SFO
-
PTY
18h 15m
1 stop
$693Avianca
Wed, Jul 15 - Sun, Jul 19
Avianca Logo
3:50 pm - 6:25 am
PTY
-
SFO
16h 35m
2 stops
Avianca Logo
11:55 pm - 10:30 am
SFO
-
PTY
8h 35m
1 stop
$694Avianca
Thu, Jul 16 - Mon, Jul 20
Multiple Airlines Logo
5:30 am - 8:45 pm
PTY
-
SFO
17h 15m
2 stops
Multiple Airlines Logo
8:23 pm - 10:30 am
SFO
-
PTY
36h 07m
2 stops
$695Multiple Airlines
Thu, Jul 16 - Mon, Jul 20
Avianca Logo
10:10 am - 11:55 pm
PTY
-
SFO
15h 45m
2 stops
Avianca Logo
11:55 pm - 10:30 am
SFO
-
PTY
8h 35m
1 stop
$696Avianca
Sat, Oct 24 - Sun, Nov 8
Avianca Logo
10:10 am - 10:35 pm
PTY
-
SFO
14h 25m
2 stops
Avianca Logo
1:20 pm - 8:50 am
SFO
-
PTY
16h 30m
2 stops
$703Avianca
Sun, Jul 12 - Sat, Jul 25
Avianca Logo
3:50 pm - 6:25 am
PTY
-
SFO
16h 35m
2 stops
Avianca Logo
11:55 pm - 5:00 pm
SFO
-
PTY
15h 05m
2 stops
$704Avianca
Booking Insights

KAYAK's insights & trends for Panama City to San Francisco flights

Get data-powered insights and trends into flights from Panama City to San Francisco to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Panama City to San Francisco?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Panama City to San Francisco departing in August.

What’s the cheapest day of the week to fly from Panama City to San Francisco?

The average price of all round-trip flights from Panama City to San Francisco clicked on KAYAK for each day over the last 12 months.

If you are looking for a flight deal from Panama City to San Francisco, look for departures on Fridays and avoid leaving on a Sunday, as it's usually the priciest day. When flying back from San Francisco, Monday is the cheapest day to fly and Saturday is the most expensive.

What is the cheapest month to fly from Panama City to San Francisco?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Panama City to San Francisco, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Panama City to San Francisco is September, where tickets cost $609 (return) on average. On the other hand, the most expensive months are February and March, where the average cost of round-trip tickets is $793 and $780 respectively.

Can I save money by flying with a layover from Panama City to San Francisco?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

Yes, flying with a layover may cost you more time, but you can also save money on the route, with a 1 stop layover the cheapest option at $767 on average.

How far in advance should I book a flight from Panama City to San Francisco?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Panama City to San Francisco, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Panama City to San Francisco, you should book around 6 weeks before departure, which saves you about 22% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 24 weeks before departure.

Expert advice

Expert advice for your flight from Panama City to San Francisco

 
AI-powered summary based on content written by travel experts. AI can make mistakes.
KAYAK teamed up with top travel experts to share the best tips for your journey.
Our travel experts
Ramsey Qubein

Ramsey Qubein

Expert on Copa Airlines

An avid traveler and aviation expert who has visited 173 countries, all 50 states and seven continents, Ramsey Qubein flies nearly 400,000 miles a year. As a North Carolina-based freelance journalist for publications including Conde Nast Traveler, Forbes, USA Today and Bloomberg among others, he explores the latest trends in aviation, hospitality, cruises and business.

Stefanie Waldek

Stefanie Waldek

Expert on United Airlines

Stefanie Waldek is a freelance space, travel, and design writer based in Saratoga Springs, NY. Her words have appeared in Space.com, Travel + Leisure, Condé Nast Traveler, Architectural Digest, and House Beautiful, among other publications. An expert in aviation and expedition cruising, Stefanie is frequently up in the air or on the sea, likely en route to Antarctica or the Arctic.

Mark Chesnut

Mark Chesnut

Expert on PTY

Mark Chesnut is a travel writer and public speaker with more than 30 years of experience. The 2019 winner of the NLGJA Excellence in Travel Writing Award, Mark is the author of the book “Prepare for Departure” and has covered air travel for multiple top consumer and trade media outlets.

Blane Bachelor

Blane Bachelor

Expert on SFO

Blane Bachelor is a journalist and editor specializing in travel and aviation who writes regularly for top global outlets. Born and raised in Florida, Blane has worked and lived in four countries, including the Netherlands, where she’s currently based with her family. Her favorite way to get to know a new destination is by running or riding a bike around town – or hearing a spooky ghost story about local history. She will always choose the window seat.

Good to know

Low seasonMarch
Cheapest flight$308
Best time to beat the crowds but there is an average 9% increase in price.
Most popular time to fly with an average 1% increase in price.
Flight from Panama City to San Francisco

When to book flights from Panama City to San Francisco

Are your dates flexible? Find out the best times to travel from Panama City to San Francisco based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Panama City to San Francisco

  • What is the cheapest flight from Panama City to San Francisco?

    In the last 5 days, the lowest price for a flight from Panama City to San Francisco was $334 for a one-way ticket and $635 for a round-trip.

  • Do I need a passport to fly between Panama City and San Francisco?

    Yes

  • Which airports will I be using when flying from Panama City to San Francisco?

    Panama City and San Francisco are both served by 1 main airport. You will leave Panama City from Panama City Tocumen Intl and will be arriving at San Francisco.

  • Which aircraft models fly most regularly from Panama City to San Francisco?

    The Boeing 737 MAX 9 is the aircraft model that flies most regularly on the Panama City to San Francisco flight route.

  • Which airline alliances offer flights from Panama City to San Francisco?

    Star Alliance is the only airline alliance operating flights between Panama City and San Francisco.

  • On which days can I fly direct from Panama City to San Francisco?

    There are nonstop flights from Panama City to San Francisco on a daily basis.

  • Which is the best airline for flights from Panama City to San Francisco, Copa Airlines or United Airlines?

    The two airlines most popular with KAYAK users for flights from Panama City to San Francisco are Copa Airlines and United Airlines. With an average price for the route of $742 and an overall rating of 7.6, Copa Airlines is the most popular choice. United Airlines is also a great choice for the route, with an average price of $735 and an overall rating of 7.4.

  • How does KAYAK find such low prices on flights from Panama City to San Francisco?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Panama City to San Francisco.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Panama City to San Francisco?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to San Francisco from Panama City is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Panama City to San Francisco?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to San Francisco with an airline and back to Panama City with another airline. Booking your flights between Panama City and SFO can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Panama City to San Francisco?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to San Francisco from Panama City up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from Panama City to San Francisco

  • Looking for a cheap flight? 25% of our users found flights on this route for $758 or less round-trip.

Prefer to fly direct from Panama City to San Francisco?

 
Direct data is based off flight results for the next 60 days. Find direct flights from all airlines flying direct from Panama City Tocumen Intl to San Francisco.
Find which airlines fly direct from Panama City Tocumen Intl Airport to San Francisco Airport, which days they fly and book direct flights.

Direct departures

Panama City Tocumen Intl to San Francisco

Monday

Copa Airlines

Copa Airlines

Tuesday

Copa Airlines

Copa Airlines

Wednesday

Copa Airlines

Copa Airlines

Thursday

Copa Airlines

Copa Airlines

Friday

Copa Airlines

Copa Airlines

Saturday

Copa Airlines

Copa Airlines

Sunday

Copa Airlines

Copa Airlines

See more direct flights

Direct returns

San Francisco to Panama City Tocumen Intl

Monday

Copa Airlines

Copa Airlines

Tuesday

Copa Airlines

Copa Airlines

Wednesday

Copa Airlines

Copa Airlines

Thursday

Copa Airlines

Copa Airlines

Friday

Copa Airlines

Copa Airlines

Saturday

Copa Airlines

Copa Airlines

Sunday

Copa Airlines

Copa Airlines

See more direct flights

Reviews of the top 3 airlines serving from Panama City to San Francisco

 
See real verified KAYAK customer reviews for airlines flying from Panama City to San Francisco. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Panama City to San Francisco? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.6
Copa AirlinesOverall score based on 1565 reviews
7.4Comfort
8.1Crew
7.8Boarding
6.9Food
6.8Entertainment
Airline reviews

stood in line to check in luggage for nearly an hour. very poor service and not excusable

4.0 OkayAnonymous, Jun 2026
PTY - AUS
Read more Copa Airlines reviews

stood in line to check in luggage for nearly an hour. very poor service and not excusable

Same as the previous flight as far as comfort and food. Entertainment didn’t have a watchable screen so everything would need to be watched on your own device in which they didn’t have a charging port that accommodated my iPhone. Seats were very uncomfortable. Staff was very friendly.

Do not book it’s a scam! They stole $1200 from me

Flight got delayed; had to go through security three times.

A lot things happened in this trip.The fly should be less stress.

Some of the Air hostesses are not that friendly. Need improvement

Had to go through security at the gate again. Had to take off shoes and go through the whole thing again even though we have global entry. They asked us to check in items bought at duty free during our layover and since we checked our luggage at the original departure airport, they forced us to check in a small backpack. None of this ever happened with other airlines. In addition, no vegetarian food option and no snacks during a 7 hr flight. Luggage limits are unusually small. This is unacceptable. Will NEVER fly Copa again and will tell friends and family to avoid this airline.

I upgraded myself to Business Class at the last minute so I had a DREAMS window seat. Seeing as I've never flown Business before everything was novel and fun for me and it made the 7 hour flight much more enjoyable for sure.

Horrible food. No wine or any other alcohol is served on the flight. Water is not served often and they refused when I asked for water in two cups. On the other hand, both going and coming back flights were on time.

it was great! Boarded on-time, reasonable leg room, pleasant staff, decent food. The only thing is we were directed to Terminal 2 when the gate was actually in Terminal 1. Smooth ride. Landed early. Got off plane easily and quickly.

The Manila airport was under renovation so there was no business class lounge. The double security check was disorganized and the flight attendants were grouchy.

Flight attendants on United are the worst in the business. Can’t be bothered to provide even basic levels of service and are as rude as anyone can get. This flight was not an exception to that rule.

United has been holding my money for a cancel on another ticket they wouldn’t let me fly for going on 5 months. Terrible service I wouldn’t choose to buy tickets or fly with united again. Very bad experience generally dishonorable and poor service .

The flight got delayed. They forgot to bring the drinks when I asked for it. The toilet is messy.

This was an overnight flight, and in the morning they did know coffee service. How you can throw passengers in a San Francisco airport at 5:40 a.m. in the morning and not giving them Coffee is a crime.

Our flight was delayed several Times due to mechanical issues. Although I understand this may happen at times, it was very inconvenient and we had to book a hotel for an overnight stay. We were traveling with my 3-yo grandson and waiting at the airport from noon until 6:30pm with no reassurance that our next rescheduled flight would depart, we had to decide what’s best for him. A day later, I found out that I may be able to demand compensation if my flight is delayed more than 4 hours. I will hav to read the fine print next time.

The staff was extremely helpful and friendly at all times! They went above and beyond to get us into an earlier flight in San Diego to make our connection in SFO possible, because our original flight did actually not make it! I did so much appreciate the UA team and how they made this possible. We also didn’t have seats together on the long flight to Singapore, but they found us seats together last moment with no additional cost! Nobody sat next to us, so that we were able to sleep! Thanks to UA for improving their service and Underpricer for booking this trip! Please be careful: 1,5 hrs for transfer in San Francisco might not be enough time in the future

Crew was great! Good meals. Had room to stretch out

How can you rate a flight when it is canceled after you leave the gate & 3 hours into sitting there or in remote area of airport after mechanical problems

Seat pitch is horrible especially on the 15 hour flight. Gate crew at SFO was Outstanding. The flight crew was also great.

This was my first time flying with you guys and my very last! This was the most horrible experience!!! There was not even tv in the plane! How cheap can this airline be!!! I paid so much for my suitcase!!! I would never fly with this airline again! The crew are very rude!

Horrible experience with Avianca, they delayed their flight and when we arrived to NYC, AVIANCA took 1 hr y 30 mins to park the airplane and all passenger get off the plane, it made me lost all my trains to get back home and I came back to my place at 3 am instead of 12 am. On the top of that their plane seat are so uncomfortable and is not enough space and killed my legs and knees, Avianca used to be good when it was a Colombian company, now after Brasilian company bought them, their service quality is bad and their flights are delayed and oversold.

It was horrible. My experience with Avianca. I didn’t know it was Pakistan international Airlines but anyway, whatever it is it is bad horrible you guys need to upgrade everything in those planes. And you guys charge $130 for a carry-on did they wanna let me in with my carry-on that I travel everywhere with the luggage you guys are such a dog thank you

The fees for baggage were outrageous. $130 for carry on and $150 for check in for an international flight. The seats did not recline. We were not even offered water. Had we known all of this, we would not have booked Avianca at all.

I was shocked flying to El Salvador that they only give you water. Everything else you have to pay for. There is no wifi or entertainment and it’s an international flight. At least back in the day they had tvs on the plane and everyone watched the same movie. Also seats do not recline, even comfort or plus.

I did not like anything, first time I use company and for sure it will be the last time, they charge for simple operations that any other average airline wouldn't charge.

The good thing is the flight was on time and the crew was really nice. They can work better the arriving with staff

The inflight entertainment did not work on a 6 hour flight The cel phone chargers did not work There was a 45 minute wait for the luggage to get off the plane.

They could offer free food and drink like other international flights.

Flight attendants to show up on time, offer drinks and food.

Everything you need to know for your flight from Panama City to San Francisco

Information on your arrival and departure airports