PTY - SFO

$276 Find Cheap Flights from Panama City to San Francisco

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Panama City to San Francisco departing on 2/28. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to San Francisco

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to San Francisco, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Panama City to San Francisco, as well as popular online travel agencies
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41,299,237 searches in the past 7 days on KAYAK

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Everything you should know

Cheapest round-trip
$500
Overall average: $793
Avianca
Tue 2/17Sun 2/22
PTY - SFO • 2 stops
Cheapest non-stop
$592
Typical prices: $610-$745
Copa Airlines
Tue 4/7Mon 4/13
PTY - SFO • Non-stop
Our travelers' advice
AI-powered summary based on content written by travel experts. AI can make mistakes.
Expect a secondary security screening at Tocumen gate.
Use BART for a budget-friendly ride from San Francisco.
Expert advice
Expert advice
Expert advice
Expert advice
Top airlines
Avianca
Cheapest • from $500 (round-trip)
Copa Airlines
Best reviews • 7.5 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
When to book
6 weeks
in advance
Our data shows that travelers who book at least 6 weeks in advance save around 49% compared to booking last minute.
Insights
Insights
Insights
Insights
When to travel
August
Cheapest • 21% price drop
June
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to San Francisco!
Flight Deals
Booking Insights
Expert advice
Flight Deals

Cheap Flights from Panama City to San Francisco (PTY-SFO)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Panama City to San Francisco that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Panama City to San Francisco

Tue, Feb 17 - Sun, Feb 22
Avianca Logo
9:45 am - 9:50 pm
PTY
-
SFO
15h 05m
2 stops
Avianca Logo
11:10 pm - 4:55 pm
SFO
-
PTY
14h 45m
2 stops
$500Avianca
Thu, Feb 12 - Thu, Feb 26
Avianca Logo
3:50 pm - 11:20 pm
PTY
-
SFO
10h 30m
1 stop
Avianca Logo
1:20 pm - 8:50 am
SFO
-
PTY
16h 30m
2 stops
$501Avianca
Fri, Feb 27 - Fri, Mar 6
Avianca Logo
5:50 pm - 9:50 pm
PTY
-
SFO
31h 00m
2 stops
Avianca Logo
1:20 pm - 4:55 pm
SFO
-
PTY
24h 35m
2 stops
$503Avianca
Sun, Mar 1 - Sat, Mar 7
Avianca Logo
7:50 pm - 12:00 pm
PTY
-
SFO
19h 10m
1 stop
Avianca Logo
1:35 am - 6:55 pm
SFO
-
PTY
14h 20m
1 stop
$510Avianca
Sun, Feb 15 - Sat, Feb 21
Avianca Logo
7:50 pm - 12:00 pm
PTY
-
SFO
19h 10m
1 stop
Avianca Logo
11:10 pm - 10:30 am
SFO
-
PTY
8h 20m
1 stop
$511Avianca
Sat, Feb 14 - Thu, Feb 19
Avianca Logo
3:50 pm - 11:20 pm
PTY
-
SFO
10h 30m
1 stop
Avianca Logo
1:20 pm - 10:30 am
SFO
-
PTY
18h 10m
1 stop
$512Avianca
Sun, Feb 22 - Wed, Feb 25
Avianca Logo
2:55 pm - 12:00 pm
PTY
-
SFO
24h 05m
2 stops
Avianca Logo
11:10 pm - 10:30 am
SFO
-
PTY
8h 20m
1 stop
$514Avianca
Sat, May 16 - Fri, May 22
Avianca Logo
10:10 am - 11:55 pm
PTY
-
SFO
15h 45m
2 stops
Avianca Logo
2:15 pm - 10:30 am
SFO
-
PTY
18h 15m
1 stop
$516Avianca
Sun, Mar 1 - Sat, Mar 7
Avianca Logo
2:55 pm - 12:00 pm
PTY
-
SFO
24h 05m
2 stops
Avianca Logo
1:35 am - 6:55 pm
SFO
-
PTY
14h 20m
1 stop
$521Avianca
Wed, Apr 8 - Wed, Apr 15
Avianca Logo
5:30 am - 12:50 pm
PTY
-
SFO
9h 20m
1 stop
Avianca Logo
2:15 pm - 1:55 am
SFO
-
PTY
9h 40m
1 stop
$547Avianca
Booking Insights

KAYAK's insights & trends for Panama City to San Francisco flights

Get data-powered insights and trends into flights from Panama City to San Francisco to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Panama City to San Francisco?

The average price of all round-trip flights from Panama City to San Francisco clicked on KAYAK for each day over the last 12 months.

If you are looking for a flight deal from Panama City to San Francisco, look for departures on Tuesdays and avoid leaving on a Thursday, as it's usually the priciest day. When flying back from San Francisco, Tuesday is the cheapest day to fly and Saturday is the most expensive.

What is the cheapest month to fly from Panama City to San Francisco?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Panama City to San Francisco, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Panama City to San Francisco is August, where tickets cost $506 (return) on average. On the other hand, the most expensive months are February and March, where the average cost of round-trip tickets is $793 and $701 respectively.

Can I save money by flying with a layover from Panama City to San Francisco?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

Yes, flying with a layover may cost you more time, but you can also save money on the route, with a 1 stop layover the cheapest option at $821 on average.

How far in advance should I book a flight from Panama City to San Francisco?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Panama City to San Francisco, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Panama City to San Francisco, you should book around 6 weeks before departure, which saves you about 49% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 21 weeks before departure.

Expert advice

Expert advice for your flight from Panama City to San Francisco

 
AI-powered summary based on content written by travel experts. AI can make mistakes.
KAYAK teamed up with top travel experts to share the best tips for your journey.
Our travel experts
Ramsey Qubein

Ramsey Qubein

Expert on Copa Airlines

An avid traveler and aviation expert who has visited 173 countries, all 50 states and seven continents, Ramsey Qubein flies nearly 400,000 miles a year. As a North Carolina-based freelance journalist for publications including Conde Nast Traveler, Forbes, USA Today and Bloomberg among others, he explores the latest trends in aviation, hospitality, cruises and business.

Stefanie Waldek

Stefanie Waldek

Expert on United Airlines

Stefanie Waldek is a freelance space, travel, and design writer based in Saratoga Springs, NY. Her words have appeared in Space.com, Travel + Leisure, Condé Nast Traveler, Architectural Digest, and House Beautiful, among other publications. An expert in aviation and expedition cruising, Stefanie is frequently up in the air or on the sea, likely en route to Antarctica or the Arctic.

Mark Chesnut

Mark Chesnut

Expert on PTY

Mark Chesnut is a travel writer and public speaker with more than 30 years of experience. The 2019 winner of the NLGJA Excellence in Travel Writing Award, Mark is the author of the book “Prepare for Departure” and has covered air travel for multiple top consumer and trade media outlets.

Blane Bachelor

Blane Bachelor

Expert on SFO

Blane Bachelor is a journalist and editor specializing in travel and aviation who writes regularly for top global outlets. Born and raised in Florida, Blane has worked and lived in four countries, including the Netherlands, where she’s currently based with her family. Her favorite way to get to know a new destination is by running or riding a bike around town – or hearing a spooky ghost story about local history. She will always choose the window seat.

Good to know

Low seasonJanuary
Cheapest flight$265
Best time to beat the crowds but there is an average 4% increase in price.
Most popular time to fly and prices are also 6% lower on average.
Flight from Panama City to San Francisco

When to book flights from Panama City to San Francisco

Are your dates flexible? Find out the best times to travel from Panama City to San Francisco based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Panama City to San Francisco

  • What is the cheapest flight from Panama City to San Francisco?

    In the last 3 days, the lowest price for a flight from Panama City to San Francisco was $276 for a one-way ticket and $500 for a round-trip.

  • Do I need a passport to fly between Panama City and San Francisco?

    Yes

  • Which airports will I be using when flying from Panama City to San Francisco?

    Panama City and San Francisco are both served by 1 main airport. You will leave Panama City from Panama City Tocumen Intl and will be arriving at San Francisco.

  • Which aircraft models fly most regularly from Panama City to San Francisco?

    The Boeing 737 MAX 9 is the aircraft model that flies most regularly on the Panama City to San Francisco flight route.

  • Which airline alliances offer flights from Panama City to San Francisco?

    Star Alliance is the only airline alliance operating flights between Panama City and San Francisco.

  • On which days can I fly direct from Panama City to San Francisco?

    There are nonstop flights from Panama City to San Francisco on a daily basis.

  • Which is the best airline for flights from Panama City to San Francisco, Copa Airlines or United Airlines?

    The two airlines most popular with KAYAK users for flights from Panama City to San Francisco are Copa Airlines and United Airlines. With an average price for the route of $651 and an overall rating of 7.5, Copa Airlines is the most popular choice. United Airlines is also a great choice for the route, with an average price of $676 and an overall rating of 7.4.

  • How does KAYAK find such low prices on flights from Panama City to San Francisco?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Panama City to San Francisco.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Panama City to San Francisco?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to San Francisco from Panama City is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Panama City to San Francisco?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to San Francisco with an airline and back to Panama City with another airline. Booking your flights between Panama City and SFO can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Panama City to San Francisco?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to San Francisco from Panama City up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from Panama City to San Francisco

  • Looking for a cheap flight? 25% of our users found flights on this route for $1,157 or less one-way and $411 or less round-trip.

Prefer to fly direct from Panama City to San Francisco?

 
Direct data is based off flight results for the next 60 days. Find direct flights from all airlines flying direct from Panama City Tocumen Intl to San Francisco.
Find which airlines fly direct from Panama City Tocumen Intl Airport to San Francisco Airport, which days they fly and book direct flights.

Direct departures

Panama City Tocumen Intl to San Francisco

Monday

Copa Airlines

Copa Airlines

Tuesday

Copa Airlines

Copa Airlines

Wednesday

Copa Airlines

Copa Airlines

Thursday

Copa Airlines

Copa Airlines

Friday

Copa Airlines

Copa Airlines

Saturday

Copa Airlines

Copa Airlines

Sunday

Copa Airlines

Copa Airlines

See more direct flights

Direct returns

San Francisco to Panama City Tocumen Intl

Monday

Copa Airlines

Copa Airlines

Tuesday

Copa Airlines

Copa Airlines

Wednesday

Copa Airlines

Copa Airlines

Thursday

Copa Airlines

Copa Airlines

Friday

Copa Airlines

Copa Airlines

Saturday

Copa Airlines

Copa Airlines

Sunday

Copa Airlines

Copa Airlines

See more direct flights

Reviews of the top 3 airlines serving from Panama City to San Francisco

 
See real verified KAYAK customer reviews for airlines flying from Panama City to San Francisco. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Panama City to San Francisco? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.5
Copa AirlinesOverall score based on 1559 reviews
6.8Entertainment
8.1Crew
7.4Comfort
7.8Boarding
6.8Food
Airline reviews

A lot things happened in this trip.The fly should be less stress.

6.0 GoodIrma, Jan 2026
PTY - MIA
Read more Copa Airlines reviews

A lot things happened in this trip.The fly should be less stress.

Horrible. No TV or any type of entertainment on board. Passwnger listening to/watching stuff on their own phone with no headphones making it noise and uncomfortable for everyone else, little/tiny food portions, old seats, useless wifi (cant access anything). Horrible exlerience especially it was a lomg distance flight with kids.

The flight was good overall. Everything went smoothly, although the landing was a bit rough. Still, it was a pleasant experience

I always enjoy flying Copa. There are very few airlines where I can enjoy a comfortable sleep in-flight. The snacks weren't the best, but they sufficed. The in-flight entertainment was fantastic, and I crossed another movie off my watch list.

Some of the Air hostesses are not that friendly. Need improvement

As always, Copa Airlines is great to fly on. The flights are always on time, the staff are pleasant and helpful and it's always a wonderful flying experience.

We had a great flight just wished they had a tv so we can see a movie that would of made my trip excellent.

horrible service, food was an embarrassment, no charging for cellphones, stay away

Great experience with a crew always thinking in the passenger

Had to go through security at the gate again. Had to take off shoes and go through the whole thing again even though we have global entry. They asked us to check in items bought at duty free during our layover and since we checked our luggage at the original departure airport, they forced us to check in a small backpack. None of this ever happened with other airlines. In addition, no vegetarian food option and no snacks during a 7 hr flight. Luggage limits are unusually small. This is unacceptable. Will NEVER fly Copa again and will tell friends and family to avoid this airline.

Very poor. The flight was delayed from Toronto because some forget to do there job . I got to my connecting gate in San Francisco 10 minutes before the departure.but this didn’t let me board even though the flight was still there for an other 30 minutes. The the gentleman at the unite airline desk told me that they usually wait for passengers but air Canada called and told them not to we I been rerouted to Manila instead of Hong Kong . In San Francisco they mad me check in my carryon bag . I was told the it will directly go yo ho chi minn cuyt but I was told that by the Vietnams airline desk that’s not there I’m 10 hours behind my scheduled flight and looks like I I’m going without baggage. I don’t have a chance of catching ..

First class ticket gets you a choice of chips or nuts. . Just like economy Southwest. Also no screen in the seats. This is first class???!

Flight arrived 30 min early and bag was waiting at the baggage pickup. United Club HNL was one of the nicest in the system

Mean flight attendant. I wanted to reuse my plastic cup, but he (Matthew) said he can't for safety. I then said "I don't want water then" and he poured me a glass. I hope Matthew gets herpes and spends the rest of his life poor, lonely, and homeless.

Yet another flight in which beverage and snack service was skipped. Other that that, firmly mediocre. Landed early, to gate late due to congestion at the gates. Airline's fault or airports fault: unknown.

Both flights delayed. 2nd flight over 3 hours late mechanical issues

It was good but only meal served is very less. Meantime good to add rice and chicken in one of meal

Teeny tiny bathrooms, crew was not realistic about when we'd arrive.

On the way my flight entertainment wouldn’t work the screen went black and no matter how many times I tried to turn it on it wouldn’t. Food was surprisingly good but the tray tables were tiny so you couldn’t get anything else on the table. The seats hardly go back and are not overly comfortable. Wouldn’t fly United again.

Flight was late - I was downgraded from first class to coach

Horrible experience with Avianca, they delayed their flight and when we arrived to NYC, AVIANCA took 1 hr y 30 mins to park the airplane and all passenger get off the plane, it made me lost all my trains to get back home and I came back to my place at 3 am instead of 12 am. On the top of that their plane seat are so uncomfortable and is not enough space and killed my legs and knees, Avianca used to be good when it was a Colombian company, now after Brasilian company bought them, their service quality is bad and their flights are delayed and oversold.

Pros: we leave and arrive on time Cons: the most uncomfortable seats ever. You cant recline at all your seats. No entertainment No TVs flight attendants didn't provide even a glass of water. You have to go to back of the airplane and ask for one. I am Colombian and I remember seeing the flight attendants very neat, elegants which is or was a staple of Avianca.it was one with tennis shoes, no male up, the hair was messy... that was really odd.

The flight attendant smashed her beverage cart into my knee, causing significant amount of pain. The seats were extremely uncomfortable. No food or drink is offered unless you want to pay the ridiculous prices for it. The schedule of flying in the overnight hours is also very uncomfortable.

Here we have another airline flying to Guatemala but doesn't have a plus or a less, just in the middle. Why? Well, first we don't have even free water Movie selection is poor Seats don't recline in some places Food selection is carb based Forgot to mention, customer service on the web is the worst. Good things; Very reliable on schedule Kind crew

Last seat of Bussines Class it does recline but passenger seating behind kept pushing since they did not have space once my seat was reclined

I handed in my suitcase in perfect condition at SAL Airport. And in MIA Airport I received it with one corner broken and the wheels bent.

I like the crew members they're very friendly. Clean plane. The flight was on time. I dont like the comfort my car seat its better that the plane seats. They charge for everything. This airline was very good. Now it's a low cost airline

This low cost airline looks and fells more like a local bus. In a 6 hour flight not being able to recline a seat is torture. The only thing available with no charge is a glass of water provided by, mostly, rude staff. Our luggage didn’t arrive

6 hour flight and have to pay for everything 100 dollars to add a carry-on bag is insane

Luggage lost and nowhere to be found, no response from either airline regarding my bag

Everything you need to know for your flight from Panama City to San Francisco

Information on your arrival and departure airports