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Find Flight Deals from San Francisco to Des Moines (SFO - DSM)

Dates flexible? Here are the best fares found in the past 48 hours...

Book cheap flights from San Francisco to Des Moines

(Round-trip)
Depart: Mon Apr 13 2015 Return: Sat Apr 18 2015 Trip spans 6 days
American Airlines
American Airlines
SFO
8:55p
DSM
2:52a
5h 57m
1 stop
DSM
11:29a
SFO
8:23p
8h 54m
1 stop
Depart: Fri May 1 2015 Return: Mon May 4 2015 Trip spans 4 days
Delta
Delta
SFO
3:30a
DSM
10:33a
7h 03m
1 stop
DSM
1:15p
SFO
7:42p
6h 27m
1 stop
Depart: Sat May 9 2015 Return: Mon May 18 2015 Trip spans 10 days
United
United
SFO
4:50a
DSM
10:44a
5h 54m
1 stop
DSM
4:03p
SFO
9:59p
5h 56m
1 stop
Depart: Tue Apr 14 2015 Return: Fri Apr 17 2015 Trip spans 4 days
American Airlines
American Airlines
SFO
8:55p
DSM
2:52a
5h 57m
1 stop
DSM
11:29a
SFO
8:23p
8h 54m
1 stop
Depart: Wed Apr 15 2015 Return: Fri Apr 17 2015 Trip spans 3 days
American Airlines
American Airlines
SFO
1:30a
DSM
8:32a
7h 02m
1 stop
DSM
11:29a
SFO
8:23p
8h 54m
1 stop
Depart: Thu Apr 16 2015 Return: Fri Apr 17 2015 Trip spans 2 days
American Airlines
American Airlines
SFO
2:00a
DSM
8:32a
6h 32m
1 stop
DSM
11:29a
SFO
6:44p
7h 15m
1 stop
Depart: Sun May 3 2015 Return: Tue May 12 2015 Trip spans 10 days
Delta
Delta
SFO
8:35p
DSM
4:34a
7h 59m
1 stop
DSM
3:00a
SFO
9:22a
6h 22m
1 stop
Depart: Mon May 4 2015 Return: Tue May 12 2015 Trip spans 9 days
American Airlines
American Airlines
SFO
7:55p
DSM
2:58a
7h 03m
1 stop
DSM
11:35a
SFO
6:40p
7h 05m
1 stop
Depart: Sun May 24 2015 Return: Thu May 28 2015 Trip spans 5 days
Delta
Delta
SFO
2:40a
DSM
10:49a
8h 09m
1 stop
DSM
10:30a
SFO
5:41p
7h 11m
1 stop
Depart: Tue Mar 31 2015 Return: Tue Apr 14 2015 Trip spans 15 days
American Airlines
American Airlines
SFO
1:30a
DSM
8:28a
6h 58m
1 stop
DSM
3:20a
SFO
10:42a
7h 22m
1 stop
Depart: Wed Apr 1 2015 Return: Mon Apr 13 2015 Trip spans 13 days
United
United
SFO
8:45a
DSM
4:36p
7h 51m
1 stop
DSM
1:19p
SFO
9:53p
8h 34m
1 stop
Depart: Tue May 19 2015 Return: Wed May 27 2015 Trip spans 9 days
Multiple Airlines
Multiple Airlines
SFO
4:40a
DSM
11:26a
6h 46m
1 stop
DSM
10:30a
SFO
7:42p
9h 12m
1 stop
Depart: Fri Apr 17 2015 Return: Sat Apr 18 2015 Trip spans 2 days
Multiple Airlines
Multiple Airlines
SFO
2:00a
DSM
6:35a
4h 35m
1 stop
DSM
4:20a
SFO
11:51a
7h 31m
1 stop
Depart: Mon May 18 2015 Return: Wed May 27 2015 Trip spans 10 days
Multiple Airlines
Multiple Airlines
SFO
8:50p
DSM
3:07a
6h 17m
1 stop
DSM
10:30a
SFO
7:42p
9h 12m
1 stop
Depart: Sat Mar 14 2015 Return: Wed Mar 25 2015 Trip spans 12 days
Multiple Airlines
Multiple Airlines
SFO
8:55a
DSM
2:25p
5h 30m
1 stop
DSM
2:40p
SFO
9:01p
6h 21m
1 stop
Depart: Wed May 20 2015 Return: Wed May 27 2015 Trip spans 8 days
Multiple Airlines
Multiple Airlines
SFO
1:25a
DSM
8:37a
7h 12m
1 stop
DSM
10:30a
SFO
7:42p
9h 12m
1 stop
Depart: Wed Mar 11 2015 Return: Wed Mar 25 2015 Trip spans 15 days
Frontier
Frontier
SFO
6:15a
DSM
12:00p
5h 45m
1 stop
DSM
2:40p
SFO
9:01p
6h 21m
1 stop
Depart: Thu Apr 9 2015 Return: Mon Apr 13 2015 Trip spans 5 days
United
United
SFO
8:50a
DSM
4:29p
7h 39m
1 stop
DSM
1:19p
SFO
9:53p
8h 34m
1 stop
Depart: Sat May 16 2015 Return: Wed May 20 2015 Trip spans 5 days
United
United
SFO
4:00a
DSM
10:44a
6h 44m
1 stop
DSM
4:03p
SFO
9:59p
5h 56m
1 stop
Depart: Wed Mar 18 2015 Return: Sat Mar 21 2015 Trip spans 4 days
US Airways
US Airways
SFO
4:06a
DSM
10:39a
6h 33m
1 stop
DSM
4:55p
SFO
11:01p
6h 06m
1 stop
Change your search
Airports
Origin

San Francisco
$324
Destination

Des Moines
$324