SFO - VVI

$395 Find Cheap Flights from San Francisco to Santa Cruz de la Sierra - Compare and Save

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1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$816
Typical prices: $796-$1,103
Copa Airlines
Tue 3/20Wed 3/28
SFO - VVI • 1 stop
Cheapest one-way
$395
Typical prices: $304-$450
Copa Airlines
Thu 10/25
SFO - VVI • 1 stop
Nonstop flights
Not available
There are currently no direct flights between San Francisco and Santa Cruz de la Sierra. You'll need to take a connecting flight to reach the destination.
Insights
Insights
When to travel
March
Cheapest • 26% price drop
January
Most popular
Good to know
+1
Good to know
+1
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We hope you love your trip to Santa Cruz de la Sierra!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from San Francisco to Santa Cruz de la Sierra (SFO-VVI)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from San Francisco to Santa Cruz de la Sierra

Sat, Mar 20 - Sun, Mar 28
Copa Airlines Logo
7:55 pm - 10:00 pmSFO  San Francisco-VVI Santa Cruz de la Sierra Viru Viru Intl
23h 05m1 stop Panama City Tocumen Intl
Copa Airlines Logo
9:56 am - 11:40 pmVVI  Santa Cruz de la Sierra Viru Viru Intl-SFO San Francisco
16h 44m1 stop Panama City Tocumen Intl
$816Copa Airlines
Sun, Feb 28 - Sun, Mar 7
Copa Airlines Logo
7:36 pm - 10:42 pmSFO  San Francisco-VVI Santa Cruz de la Sierra Viru Viru Intl
23h 06m1 stop Panama City Tocumen Intl
Copa Airlines Logo
9:56 am - 11:05 pmVVI  Santa Cruz de la Sierra Viru Viru Intl-SFO San Francisco
17h 09m1 stop Panama City Tocumen Intl
$816Copa Airlines
Fri, Jan 8 - Sat, Feb 6
United Airlines Logo
9:40 pm - 10:46 pmSFO  San Francisco-VVI Santa Cruz de la Sierra Viru Viru Intl
45h 06m2 stops Newark Panama City Tocumen Intl
United Airlines Logo
11:55 am - 12:30 amVVI  Santa Cruz de la Sierra Viru Viru Intl-SFO San Francisco
16h 35m2 stops Panama City Tocumen Intl Houston George Bush Intcntl
$831United Airlines
Sun, Nov 8 - Sat, Nov 14
United Airlines Logo
11:20 pm - 10:38 pmSFO  San Francisco-VVI Santa Cruz de la Sierra Viru Viru Intl
19h 18m2 stops Washington, D.C. Dulles Intl Panama City Tocumen Intl
United Airlines Logo
11:41 am - 12:04 amVVI  Santa Cruz de la Sierra Viru Viru Intl-SFO San Francisco
16h 23m2 stops Panama City Tocumen Intl Houston George Bush Intcntl
$831United Airlines
Sat, Nov 7 - Sat, Nov 14
United Airlines Logo
10:50 am - 10:38 pmSFO  San Francisco-VVI Santa Cruz de la Sierra Viru Viru Intl
31h 48m2 stops Washington, D.C. Dulles Intl Panama City Tocumen Intl
United Airlines Logo
11:41 am - 9:50 amVVI  Santa Cruz de la Sierra Viru Viru Intl-SFO San Francisco
26h 09m2 stops Panama City Tocumen Intl Houston George Bush Intcntl
$831United Airlines
Sun, Feb 28 - Sat, Mar 6
Avianca Logo
11:00 pm - 2:40 amSFO  San Francisco-VVI Santa Cruz de la Sierra Viru Viru Intl
23h 40m2 stops San Salvador El Salvador Intl Bogotá El Dorado
Avianca Logo
3:45 am - 11:55 amVVI  Santa Cruz de la Sierra Viru Viru Intl-SFO San Francisco
36h 10m2 stops Bogotá El Dorado San Salvador El Salvador Intl
$843Avianca
Sun, Dec 6 - Mon, Dec 14
Copa Airlines Logo
12:45 am - 10:48 pmSFO  San Francisco-VVI Santa Cruz de la Sierra Viru Viru Intl
18h 03m2 stops Houston George Bush Intcntl Panama City Tocumen Intl
Copa Airlines Logo
11:42 am - 9:48 amVVI  Santa Cruz de la Sierra Viru Viru Intl-SFO San Francisco
26h 06m2 stops Panama City Tocumen Intl Houston George Bush Intcntl
$845Copa Airlines
Sat, Nov 7 - Thu, Nov 12
Avianca Logo
1:30 am - 2:40 amSFO  San Francisco-VVI Santa Cruz de la Sierra Viru Viru Intl
21h 10m2 stops San Salvador El Salvador Intl Bogotá El Dorado
Avianca Logo
3:45 am - 11:55 amVVI  Santa Cruz de la Sierra Viru Viru Intl-SFO San Francisco
36h 10m2 stops Bogotá El Dorado San Salvador El Salvador Intl
$851Avianca
Mon, Nov 23 - Sat, Nov 28
Avianca Logo
1:15 pm - 2:40 amSFO  San Francisco-VVI Santa Cruz de la Sierra Viru Viru Intl
33h 25m2 stops San Salvador El Salvador Intl Bogotá El Dorado
Avianca Logo
3:45 am - 9:40 pmVVI  Santa Cruz de la Sierra Viru Viru Intl-SFO San Francisco
45h 55m2 stops Bogotá El Dorado San Salvador El Salvador Intl
$861Avianca
Sat, Feb 6 - Sat, Feb 13
Copa Airlines Logo
7:36 pm - 3:43 amSFO  San Francisco-VVI Santa Cruz de la Sierra Viru Viru Intl
28h 07m1 stop Panama City Tocumen Intl
Copa Airlines Logo
1:18 am - 5:25 pmVVI  Santa Cruz de la Sierra Viru Viru Intl-SFO San Francisco
20h 07m1 stop Panama City Tocumen Intl
$881Copa Airlines
Booking Insights

Price, demand and travel trends for San Francisco to Santa Cruz de la Sierra flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

How much is a round-trip flight from San Francisco to Santa Cruz de la Sierra?

Round-trip flights from San Francisco to Santa Cruz de la Sierra typically range from $796 to $1,103. The lowest price found in the past 5 days was $816, on Copa Airlines.

What's the cheapest day of the week to fly from San Francisco to Santa Cruz de la Sierra?

Based on deals KAYAK users found in the last 12 months, Wednesday is the cheapest day of the week to fly from San Francisco to Santa Cruz de la Sierra. It’s 16% cheaper than the average day, while Monday is the most expensive, with prices 22% higher.

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Key details for San Francisco to Santa Cruz de la Sierra flights

Low season

October

Cheapest flight

$395
Beat the crowds with an average 90% drop in travelers.
The most popular month to fly with an average 35% increase in travelers.
One-way flight from San Francisco to Santa Cruz de la Sierra

When to book flights from San Francisco to Santa Cruz de la Sierra

Are your dates flexible? Find out the best times to travel from San Francisco to Santa Cruz de la Sierra based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your San Francisco to Santa Cruz de la Sierra flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines and booking tips.

  • What cabin classes can I book on flights from San Francisco to Santa Cruz de la Sierra?

    Three cabin classes are available on flights from San Francisco to Santa Cruz de la Sierra:

    • Economy Class
    • Business Class
    • First Class

  • How long is a flight from San Francisco to Santa Cruz de la Sierra?

    A nonstop flight from San Francisco to Santa Cruz de la Sierra takes 00m, covering 5,414 miles.

  • Do I need a passport to fly from San Francisco to Santa Cruz de la Sierra?

    Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.

  • How much should I expect to pay for a San Francisco to Santa Cruz de la Sierra flight?

    Round-trip flights from San Francisco to Santa Cruz de la Sierra range from $796 to $1,103, with an average of $959 over the past 12 months. Anything below $796 counts as a good deal.

  • Have flight prices from San Francisco to Santa Cruz de la Sierra changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $816 to $6,754. That means the highest observed fare was about 8x higher than the lowest one.

  • How are flight prices from San Francisco to Santa Cruz de la Sierra looking right now?

    One-way fares from San Francisco to Santa Cruz de la Sierra are currently higher than usual. Average one-way flight prices are about $602, which is 72% above the typical average for this route.

  • Which airports can I use when flying from San Francisco to Santa Cruz de la Sierra?

    Flights from San Francisco to Santa Cruz de la Sierra usually depart from San Francisco (SFO) and arrive at Santa Cruz de la Sierra Viru Viru Intl (VVI).

  • Which airports do connecting flights from San Francisco to Santa Cruz de la Sierra pass through?

    Most connecting flights from San Francisco to Santa Cruz de la Sierra pass through Panama City Tocumen Intl (PTY), which handles 100% of one-stop traffic on this route.

  • Can I save money by using flexible dates for flights from San Francisco to Santa Cruz de la Sierra?

    Yes. Flexible dates can save you up to 31% on flights from San Francisco to Santa Cruz de la Sierra. Wednesday is the cheapest departure day at $812 round-trip on average, while Monday is the most expensive at $1,173, a difference of $361.

    KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • What is the time difference between San Francisco and Santa Cruz de la Sierra?

    Santa Cruz de la Sierra is 3 hours ahead of San Francisco (Bolivia Time vs Pacific Time). Plan for the time shift when scheduling connections or first-day activities.

Your guide to booking San Francisco to Santa Cruz de la Sierra flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates are flexible, aim for a Wednesday departure and avoid flying on Monday. On this route, Wednesday flights average $812, about $361 less than Monday fares (31% savings) based on the last 12 months.
  • If you can choose when to travel, plan your San Francisco to Santa Cruz de la Sierra trip for March. Fares historically average $712 round-trip in that month - typically $955 less than the most expensive month, which is December (based on the last 12 months).
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to Santa Cruz de la Sierra Viru Viru Intl Airport.

    • Sun Hotel

More options for your flight from San Francisco to Santa Cruz de la Sierra

Complete your trip to Santa Cruz de la Sierra with a hotel stay or car rental

Car rentals in Santa Cruz de la Sierra
Hotels in Santa Cruz de la Sierra