SFO - VVI

$368 Find Cheap Flights from San Francisco to Santa Cruz de la Sierra - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from San Francisco to Santa Cruz de la Sierra departing on 8/10. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$768
Typical prices: $737-$1,028
Multiple Airlines
Mon 9/21Tue 10/6
SFO - VVI • 2 stops
Cheapest one-way
$368
Typical prices: $309-$404
Multiple Airlines
Mon 8/10
SFO - VVI • 2 stops
Top airlines
Cheapest • from $771 (round-trip)
Best reviews • 7.6 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between San Francisco and Santa Cruz de la Sierra. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
When to travel
Cheapest • 62% price drop
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
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We hope you love your trip to Santa Cruz de la Sierra!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from San Francisco to Santa Cruz de la Sierra (SFO-VVI)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from San Francisco to Santa Cruz de la Sierra that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from San Francisco to Santa Cruz de la Sierra

Mon, Sep 21 - Tue, Oct 6
Multiple Airlines Logo
4:40 pm - 2:30 am
SFO
-
VVI
30h 50m
2 stops
Multiple Airlines Logo
3:35 am - 6:29 pm
VVI
-
SFO
17h 54m
2 stops
$768Multiple Airlines
Sun, Oct 18 - Thu, Oct 22
United Airlines Logo
10:35 pm - 3:38 am
SFO
-
VVI
26h 03m
2 stops
United Airlines Logo
11:47 am - 10:51 pm
VVI
-
SFO
38h 04m
2 stops
$771United Airlines
Tue, Aug 11 - Sat, Nov 7
Copa Airlines Logo
8:21 pm - 10:40 pm
SFO
-
VVI
23h 19m
1 stop
Copa Airlines Logo
1:08 am - 11:12 pm
VVI
-
SFO
26h 04m
1 stop
$774Copa Airlines
Sun, Aug 2 - Sat, Aug 8
Copa Airlines Logo
8:21 pm - 10:40 pm
SFO
-
VVI
23h 19m
1 stop
Copa Airlines Logo
1:12 am - 11:40 pm
VVI
-
SFO
25h 28m
1 stop
$870Copa Airlines
Tue, Nov 24 - Mon, Nov 30
Avianca Logo
1:35 am - 2:35 am
SFO
-
VVI
21h 00m
2 stops
Avianca Logo
3:40 am - 9:50 pm
VVI
-
SFO
22h 10m
2 stops
$967Avianca
Sun, Aug 2 - Sat, Aug 8
Avianca Logo
2:15 pm - 2:30 am
SFO
-
VVI
33h 15m
2 stops
Avianca Logo
3:35 am - 6:25 am
VVI
-
SFO
29h 50m
3 stops
$1,002Avianca
Tue, Jul 21 - Sat, Jul 25
Avianca Logo
2:30 am - 2:30 am
SFO
-
VVI
21h 00m
2 stops
Avianca Logo
3:35 am - 6:25 am
VVI
-
SFO
53h 50m
3 stops
$1,008Avianca
Sun, Aug 2 - Sat, Aug 8
Avianca Logo
2:15 pm - 2:30 am
SFO
-
VVI
33h 15m
2 stops
Avianca Logo
3:35 am - 6:25 am
VVI
-
SFO
29h 50m
3 stops
$1,017Avianca
Thu, Jul 30 - Sat, Aug 29
Copa Airlines Logo
8:16 pm - 3:35 am
SFO
-
VVI
28h 19m
1 stop
Copa Airlines Logo
1:12 am - 11:40 pm
VVI
-
SFO
25h 28m
1 stop
$1,038Copa Airlines
Thu, Jul 30 - Sat, Aug 29
Avianca Logo
2:15 pm - 2:30 am
SFO
-
VVI
33h 15m
2 stops
Avianca Logo
3:35 am - 6:25 am
VVI
-
SFO
29h 50m
3 stops
$1,049Avianca
Booking Insights

KAYAK's insights & trends for San Francisco to Santa Cruz de la Sierra flights

Get data-powered insights and trends into flights from San Francisco to Santa Cruz de la Sierra to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from San Francisco to Santa Cruz de la Sierra?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from San Francisco to Santa Cruz de la Sierra departing in September.

What is the cheapest month to fly from San Francisco to Santa Cruz de la Sierra?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from San Francisco to Santa Cruz de la Sierra, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from San Francisco to Santa Cruz de la Sierra is March, where tickets cost $356 (return) on average. On the other hand, the most expensive months are December and October, where the average cost of round-trip tickets is $1,667 and $1,192 respectively.

Good to know

Low seasonJune
Cheapest flight$368
Best time to beat the crowds but there is an average 21% increase in price.
Most popular time to fly and prices are also 1% lower on average.
Flight from San Francisco to Santa Cruz de la Sierra

When to book flights from San Francisco to Santa Cruz de la Sierra

Are your dates flexible? Find out the best times to travel from San Francisco to Santa Cruz de la Sierra based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from San Francisco to Santa Cruz de la Sierra

  • What is the cheapest flight from San Francisco to Santa Cruz de la Sierra?

    In the last 5 days, the lowest price for a flight from San Francisco to Santa Cruz de la Sierra was $368 for a one-way ticket and $768 for a round-trip.

  • Do I need a passport to fly between San Francisco and Santa Cruz de la Sierra?

    Yes, you’ll need a passport to travel to Santa Cruz de la Sierra from San Francisco.

  • Which aircraft models fly most regularly from San Francisco to Santa Cruz de la Sierra?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from San Francisco to Santa Cruz de la Sierra?

    Star Alliance is the only airline alliance operating flights between San Francisco and Santa Cruz de la Sierra.

  • Which is the best airline for flights from San Francisco to Santa Cruz de la Sierra, Copa Airlines or United Airlines?

    The two airlines most popular with KAYAK users for flights from San Francisco to Santa Cruz de la Sierra are Copa Airlines and United Airlines. With an average price for the route of $853 and an overall rating of 7.6, Copa Airlines is the most popular choice. United Airlines is also a great choice for the route, with an average price of $1,027 and an overall rating of 7.4.

  • How does KAYAK find such low prices on flights from San Francisco to Santa Cruz de la Sierra?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from San Francisco to Santa Cruz de la Sierra.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from San Francisco to Santa Cruz de la Sierra?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santa Cruz de la Sierra from San Francisco is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from San Francisco to Santa Cruz de la Sierra?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Santa Cruz de la Sierra with an airline and back to San Francisco with another airline. Booking your flights between San Francisco and VVI can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from San Francisco to Santa Cruz de la Sierra?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santa Cruz de la Sierra from San Francisco up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 3 airlines serving from San Francisco to Santa Cruz de la Sierra

 
See real verified KAYAK customer reviews for airlines flying from San Francisco to Santa Cruz de la Sierra. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from San Francisco to Santa Cruz de la Sierra? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.6
Copa AirlinesOverall score based on 1566 reviews
7.4Comfort
7.8Boarding
8.1Crew
6.8Entertainment
6.9Food
Airline reviews

There should be a warning regarding the quality of the aircraft on the website as we reserve the tickets. There was no TV or any type of screen onboard. The wifi they offer is good for nothing. Traveling 9 hours straight with kids and no type of entetainment was horrible. I wish I had been informed prior so I could buy a ticket with another airline. The food was a joke too. A very tiny portion per passenger. They also charged $100 per checked bag. With United I used to pay $60. So, fair to say that I wont be flying Copa anymore. Their aircraft was super old, outdated, no entertainment, with nearly no onboard food.

2.0 MediocreAnonymous, Dec 2025
LAS - PTY
Read more Copa Airlines reviews

There should be a warning regarding the quality of the aircraft on the website as we reserve the tickets. There was no TV or any type of screen onboard. The wifi they offer is good for nothing. Traveling 9 hours straight with kids and no type of entetainment was horrible. I wish I had been informed prior so I could buy a ticket with another airline. The food was a joke too. A very tiny portion per passenger. They also charged $100 per checked bag. With United I used to pay $60. So, fair to say that I wont be flying Copa anymore. Their aircraft was super old, outdated, no entertainment, with nearly no onboard food.

It would have been better if they don't separate families in seating. We were seated in the aile row in the middle of a family of four. It would have been better if they they seat the family of four together than separated.

It was good, plane is a bit older so seats are somewhat flat

Very good flight and crew Food was a surprise on a short flight

Biggest issue was that they only had two restrooms in the back of the aircraft. Too many people for only two restrooms. The trash was overflowing and there was paper on the floor too. Long lines in the isle to use it. Food was also a bit meh. They don’t offer snacks with drinks, so you might want to buy a snack to hold you off on a longer trip, since the meals are very small.

Everything was smooth and crew was very polite and friendly.

I like that they served a mail, I’m not sure about the in-flight entertainment. I didn’t really check. staff helped me with my luggage. Smooth boarding smooth takeoff smooth flight

The seats had plenty of leg room and the staff were very nice.

Copa performed as expected for the amount of money I was willing to spend for the flight; it wasn’t exceptional but it was not bad in any way either. The crew was good; friendly and straightforward. The food was airplane food, so no expectations there and the entertainment was lacking but that was my fault for owning an IPhone with a charging port that’s not compatible with the rest of the world. I’d fly Copa again.

Left my bags in origin city on a business class ticket , spent about 2-3 days in the same clothes plus the flight .

Excellent communication from the staff. We actually arrived early. Very friendly and professional staff.

No extra snacks were available. Meals quality is terrible. Crew was not friendly.

Lost one piece of luggage even though I checked in 2.5 hours before the flight

It was perfect! United Airlines staff was extremely caring, super friendly and professional

United has maintenance issues and can then never recover. No operations ability and simple issues always turn into multiple hours long cascading delays. Worst airline on earth.

I paid for a confirmed upgraded aisle seat and was moved to a center seat in the back of the plane at the last minute.

Horrifying Almost 2 million miles. Bring your own food and drink. One coffee or drink every three hours. Have to order meals on app more than 24 hours ahead Tiny and dirty bathrooms

Easy of boarding, helpfully staff at check in, surprisingly comfortable seating

Lost of requested seat assignments. Lost my husband's meal choice

My service dog and I were asked to deplane just before they closed the door - clearly very last minute they couldn’t find the documentation that I have filled out many many times before that is for flying service animals. I purposely purchase 3seats (a whole row) since he is large and not all passengers want to sit next to a dog on a cross country flight. The plane departed with my husband on it!!! They made me fill out a hard copy of the same form and had to reschedule me on a later flight where they could find 3 seats together!! I’ve done this so many times before - clearly the error was on their part in a technology glitch - but really people - do better!! Very traumatic - and my husband had to wait for us when he landed ….so bad. Poor pup was confused and tired.

Staff are the rudest in the industry … awful customer service … will never fly Avianca again

Here we have another airline flying to Guatemala but doesn't have a plus or a less, just in the middle. Why? Well, first we don't have even free water Movie selection is poor Seats don't recline in some places Food selection is carb based Forgot to mention, customer service on the web is the worst. Good things; Very reliable on schedule Kind crew

I had to go to the boarding counter for them to enter my return flight as it’s not with Avianca. There was a long queue as there were lots of people being called to the counter.

Boarding, crew were excellent, food was ok and entertainment need to improve

There isn't much space in-between seats and even water needs to be paid for during the flight.

We were not aware carry-on bags cost extra until we arrived at the airport so, we were charged $240.00 for two small carry- on bags! There was a substantial fee for drinks and snacks. No wifi, or other entertainment was available. Waiting areas were crowded and uncomfortable.

Ok, but these people don’t give you nothing no snack no water

No water for a 5 hour flight entertainment not working seats with little room for knees when person in front of me reclined kept bumping my knees.

Awful. I checked in online and there was no option to pay for baggage, at the airport when I checked in my baggage was received and Iwas not charged. When I got to LA during the boarding process I was told I didn't pay for baggage, the crew resolved I was let in the plane. When I got to my final destination my baggage was not there. It took me two days to receive my baggage. Bad service ever!

Wasn’t able to take the trip and no one could help me with a refund or rescheduling

Everything you need to know for your flight from San Francisco to Santa Cruz de la Sierra

Information on your arrival and departure airports