SFO - VVI

$305 Find Cheap Flights from San Francisco to Santa Cruz de la Sierra

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from San Francisco to Santa Cruz de la Sierra departing on 9/26. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

KAYAK searches hundreds of travel sites at once for deals on flights to Santa Cruz de la Sierra

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from San Francisco to Santa Cruz de la Sierra, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from San Francisco to Santa Cruz de la Sierra, as well as popular online travel agencies
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Cheap Flights from San Francisco to Santa Cruz de la Sierra (SFO-VVI)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from San Francisco to Santa Cruz de la Sierra that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from San Francisco to Santa Cruz de la Sierra

Sat, Aug 9 - Thu, Aug 14
United Airlines Logo
12:30 am - 10:19 pmSFO-VVI
18h 49m2 stops
United Airlines Logo
1:09 am - 9:15 pmVVI-SFO
23h 06m1 stop
$617United Airlines
Find Deal
Sat, Aug 9 - Thu, Aug 14
United Airlines Logo
12:30 am - 10:19 pmSFO-VVI
18h 49m2 stops
United Airlines Logo
1:09 am - 9:15 pmVVI-SFO
23h 06m1 stop
$618United Airlines
Find Deal
Sat, Oct 4 - Fri, Oct 17
 Logo
10:55 am - 10:17 pmSFO-VVI
32h 22m1 stop
 Logo
2:55 am - 11:57 pmVVI-SFO
24h 02m2 stops
Sat, Oct 4 - Fri, Oct 17
 Logo
4:12 pm - 1:50 amSFO-VVI
30h 38m2 stops
 Logo
2:55 am - 8:13 pmVVI-SFO
20h 18m2 stops
Mon, Jul 14 - Tue, Jul 22
Copa Airlines Logo
1:25 am - 10:19 pmSFO-VVI
17h 54m1 stop
Copa Airlines Logo
12:15 pm - 11:40 pmVVI-SFO
14h 25m1 stop
$719Copa Airlines
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Fri, Aug 1 - Mon, Aug 11
Avianca Logo
2:20 pm - 1:50 amSFO-VVI
32h 30m2 stops
Avianca Logo
2:55 am - 10:45 pmVVI-SFO
22h 50m2 stops
$879Avianca
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Thu, Jul 31 - Mon, Aug 11
Avianca Logo
12:05 am - 1:50 amSFO-VVI
22h 45m2 stops
Avianca Logo
2:55 am - 10:45 pmVVI-SFO
22h 50m2 stops
$942Avianca
Find Deal
Sun, Oct 12 - Sun, Oct 26
LATAM Airlines Logo
6:00 am - 4:35 amSFO-VVI
19h 35m2 stops
LATAM Airlines Logo
10:16 am - 12:00 pmVVI-SFO
28h 44m2 stops
$1,069LATAM Airlines
Find Deal
Fri, Aug 29 - Mon, Sep 8
LATAM Airlines Logo
6:00 am - 10:29 amSFO-VVI
49h 29m3 stops
LATAM Airlines Logo
5:20 am - 11:13 pmVVI-SFO
20h 53m2 stops
$1,180LATAM Airlines
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Thu, Aug 28 - Sun, Sep 7
Copa Airlines Logo
1:28 am - 3:37 amSFO-VVI
23h 09m1 stop
Copa Airlines Logo
1:09 am - 9:10 pmVVI-SFO
23h 01m1 stop
$1,384Copa Airlines
Find Deal
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KAYAK's insights & trends for San Francisco to Santa Cruz de la Sierra flights

Get data-powered insights and trends into flights from San Francisco to Santa Cruz de la Sierra to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from San Francisco to Santa Cruz de la Sierra?

The average price of all round-trip flights from San Francisco to Santa Cruz de la Sierra clicked on KAYAK for each day over the last 12 months.

Your flight ticket price will generally be cheaper if you fly to Santa Cruz de la Sierra on a Friday and more expensive on a Sunday. On your return trip to San Francisco, you should consider flying back on a Tuesday, and avoid Saturdays for better deals.

What is the cheapest month to fly from San Francisco to Santa Cruz de la Sierra?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from San Francisco to Santa Cruz de la Sierra, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from San Francisco to Santa Cruz de la Sierra is March, where tickets cost $693 (return) on average. On the other hand, the most expensive months are December and January, where the average cost of round-trip tickets is $1,663 and $1,151 respectively.

How far in advance should I book a flight from San Francisco to Santa Cruz de la Sierra?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from San Francisco to Santa Cruz de la Sierra, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from San Francisco to Santa Cruz de la Sierra, you should book around 2 weeks before departure. For the absolute cheapest price, our data suggests you should book 14 weeks before departure.

Good to know

Low seasonMay
High seasonJuly
Cheapest flight$305
Best time to beat the crowds with an average 1% drop in price.
Most popular time to fly with an average 6% increase in price.
Flight from San Francisco to Santa Cruz de la Sierra

When to book flights from San Francisco to Santa Cruz de la Sierra

Are your dates flexible? Find out the best times to travel from San Francisco to Santa Cruz de la Sierra based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from San Francisco to Santa Cruz de la Sierra

  • What is the cheapest flight from San Francisco to Santa Cruz de la Sierra?

    In the last 3 days, the lowest price for a flight from San Francisco to Santa Cruz de la Sierra was $305 for a one-way ticket and $617 for a round-trip.

  • Do I need a passport to fly between San Francisco and Santa Cruz de la Sierra?

    Yes, you’ll need a passport to travel to Santa Cruz de la Sierra from San Francisco.

  • Which aircraft models fly most regularly from San Francisco to Santa Cruz de la Sierra?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from San Francisco to Santa Cruz de la Sierra?

    Star Alliance is the only airline alliance operating flights between San Francisco and Santa Cruz de la Sierra.

  • What is the most popular layover when flying to Santa Cruz de la Sierra from San Francisco?

    Panama City is the most popular layover city among KAYAK users traveling from San Francisco to Santa Cruz de la Sierra.

  • Which is the best airline for flights from San Francisco to Santa Cruz de la Sierra, Copa Airlines or United Airlines?

    The two airlines most popular with KAYAK users for flights from San Francisco to Santa Cruz de la Sierra are Copa Airlines and United Airlines. With an average price for the route of $964 and an overall rating of 7.5, Copa Airlines is the most popular choice. United Airlines is also a great choice for the route, with an average price of $822 and an overall rating of 7.4.

  • How does KAYAK find such low prices on flights from San Francisco to Santa Cruz de la Sierra?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from San Francisco to Santa Cruz de la Sierra.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from San Francisco to Santa Cruz de la Sierra?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santa Cruz de la Sierra from San Francisco is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from San Francisco to Santa Cruz de la Sierra?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Santa Cruz de la Sierra with an airline and back to San Francisco with another airline. Booking your flights between San Francisco and VVI can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from San Francisco to Santa Cruz de la Sierra?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santa Cruz de la Sierra from San Francisco up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Top 3 airlines serving from San Francisco to Santa Cruz de la Sierra

 
See real verified KAYAK customer reviews for airlines flying from San Francisco to Santa Cruz de la Sierra. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from San Francisco to Santa Cruz de la Sierra? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.5
Copa AirlinesOverall score based on 1452 reviews
6.8Entertainment
7.4Comfort
8.1Crew
6.8Food
7.8Boarding
Airline reviews

Tell people to remain in their seats during the meal/beverage distribution. Enforce boarding by group numbers. No one was checking. Tell people to turn their electronics speakers off. Bigger cups for drinks.

2.0 MediocrePaul, Jun 2025PTY - MIA
Read more Copa Airlines reviews

Tell people to remain in their seats during the meal/beverage distribution. Enforce boarding by group numbers. No one was checking. Tell people to turn their electronics speakers off. Bigger cups for drinks.

Enforce the boarding process by group numbers. Tell people to stay seated during the meal/drink distribution. It took forever to get food and drinks because people would not stay out the isle and let the crew do their jobs. Everyone wanted to go to the bathroom forcing the crew to enter and leave the isle constantly so people can pass. Tell people to keep their electronics off speaker mode. No one wants to hear phone conversations and music playing.

Placed us in the last rear row of the plane so could not recline seats because of the rear wall, and also made it more of a tight space when the passenger in front reclined their seat. While understand seat assignments, every passenger should be afforded a reclining seat. The odor control scent from the restrooms was overwhelming strong. My wife and I could not deal with it, and she suffered a terrible headache as a result. I kept getting hit by the crew since I was on the ilse seat. No apologies, nothing. They made me feel like I was supposed to take the beating for a 3 hr flight.

There was no individual at the front check in when I arrived. I waited for at least 15 minutes and walked around asking security/janitors if they could help and they did not have a solution. So I had to take my checked bag through security and they threw away some of my items. I ended up making it to the gate only a few minutes before it closed due to my waiting for an agent at check in.

The flight was delayed twice and I could not speak with anyone at the airport about checking in. The phone number to Copa - the customer service agents were polite. They are just limited at helping because they are not at the airport

My flight delayed and i misss the connection they send me to orlando no to tampa i have to pay a uber to my house

It would have been better if they don't separate families in seating. We were seated in the aile row in the middle of a family of four. It would have been better if they they seat the family of four together than separated.

I upgraded myself to Business Class at the last minute so I had a DREAMS window seat. Seeing as I've never flown Business before everything was novel and fun for me and it made the 7 hour flight much more enjoyable for sure.

It was reasonably comfortable trip considering its duration (7 hours). Crew was very good and friendly, seats very more comfortable than other planes. Only negative comment would be that the bathroom light did not get its full brightness 🙃

It was good, plane is a bit older so seats are somewhat flat

Very comfortable (upgraded to business class). The audio on my screen didn’t work, but I managed to play the audio through my phone while watching the screen.

Flight was late as pilot crew had to land at different airport in their previous flight. Passengers boarded and had to wait for pilots inside plane. Series of incomplete and unnecessary announcements by an annoying voice, rather than complete, informative announcements.

Breakfast was not loaded at SFO due to catering company change. Seems like a major airline at a major hub would have thought of something else or warned passengers to pick up food before boarding a 3 hour flight.

Boarding seemed to be organized bedlam. For what ever reason, preboarding took longer than 20 minutes. Made the plane 20 minutes late taking off. Luckily we arrived on time. Flight crew seemed very friendly. Only slight turbulence.

They hired a new catering company the same day of my flight. They botched the job by not delivering the right carts and after THREE HOURS waiting, the flight crew timed out (flight was 19 hours long and FAA rules state crew can’t work more than 14 hours long). So they CANCELED OUR FLIGHT!! Worst experience ever. Avoid UAL at all costs.

The personnel were professional and friendly. The Boeing 737 Max 9 is too claustrophobic and was very warm at both airport gates, and still warm in the air.

While the staff was pleasant and helpful, the following observations are for your awareness. There was some delay on the tarmac on take off and landing. The paid lunch/food offerings were limited. Entertainment was only available on WiFi at a cost.

get E+, a must for 5 hours flight if you are tall

Liked fold flat bed. Didn’t like having no window. Didn’t like poor choice of food and being served dinner very late, hours after take off of a 7:40pm flight. Servers not friendly. Food horrible in business class.

Everything is good except the dinner and breakfast. The sandwich is very delicious. Toilet is clean, I only use one of them. Flight attendants are very nice. 👍👍

Seats are very tight even in Plus, no complimentary snacks or beverage

Flight to Bogotá delayed by 3 h Missed connection from Bogotá to Guayaquil. Avianca unable to bring us to Baltra on time Overall delay 36h. We missed boat departure from galagos. Overall 10 day trip needed to be cancelled. Avianca was completely un-professional.

I receive a service for what I pay, so it is fair.

i think the flight was late because they were so strict about measuring everyone's personal items to try and charge them $119. It was really petty and made us late.

Terrible, We had to stay in Bogota for two days due to weather but the airline did not provide for the same day flight. Only two days later

There isn't much space in-between seats and even water needs to be paid for during the flight.

We did not know about the bag fees until check in. They are way too high. It’s insane. We also had a huge delay and everything costed extra which was very annoying.

Lounge for business was closed. Boarding was rush and stand by. Seat for business is just the middle seat blocked and some more leg room.

Flew with our two children. Paid $380 to check two bags (one was overweight). They then left the bags behind on Sunday, December 21st, with all our family’s clothes and family Christmas presents. When we arrived at our destination they told us the bags had not arrived, and they thought (but didn’t know) they were still in Boston, but that there’d be a flight the next day and the bags would arrive the next day. The next day we found out there was no flight, now we’re hoping we get our bags before we fly back out. Meanwhile, trying to get any engagement or accurate information is a waste of time. The folks at the call center are just gatekeepers, who can’t connect with any departments that actually do things to solve a problem. Getting information is made deliberately difficult. My biggest regret is that I’ve had a number of awful experiences with Avianca traveling between the US and Colombia, and still let myself get suckered into buying these tickets because the schedule was great. Never again.

We were not aware carry-on bags cost extra until we arrived at the airport so, we were charged $240.00 for two small carry- on bags! There was a substantial fee for drinks and snacks. No wifi, or other entertainment was available. Waiting areas were crowded and uncomfortable.

Everything you need to know for your flight from San Francisco to Santa Cruz de la Sierra

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