Which airports can I use when flying from Santa Cruz de la Sierra to San Francisco?

Flights from Santa Cruz de la Sierra to San Francisco usually depart from Santa Cruz de la Sierra Viru Viru Intl (VVI) and arrive at San Francisco (SFO).

What cabin classes can I book on flights from Santa Cruz de la Sierra to San Francisco?

Only Economy Class is available on flights from Santa Cruz de la Sierra to San Francisco.

Which airports do connecting flights from Santa Cruz de la Sierra to San Francisco pass through?

Most connecting flights from Santa Cruz de la Sierra to San Francisco pass through Panama City Tocumen Intl (PTY), which handles 100% of one-stop traffic on this route.

Can I save money by using flexible dates for flights from Santa Cruz de la Sierra to San Francisco?

Yes. Flexible dates can save you up to 49% on flights from Santa Cruz de la Sierra to San Francisco. Monday is the cheapest departure day at $837 round-trip on average, while Sunday is the most expensive at $1,613, a difference of $776. KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

What popular places can I visit in San Francisco?

Some of the most popular sights in San Francisco are Fisherman's Wharf, Union Square and Moscone Center. These are among the most viewed places in San Francisco on KAYAK.

How long is a flight from Santa Cruz de la Sierra to San Francisco?

A nonstop flight from Santa Cruz de la Sierra to San Francisco takes 00m, covering 5,414 miles.

Do I need a passport to fly from Santa Cruz de la Sierra to San Francisco?

Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.

Have flight prices from Santa Cruz de la Sierra to San Francisco changed much recently?

Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $1,003 to $3,928. That means the highest observed fare was about 4x higher than the lowest one.

How are flight prices from Santa Cruz de la Sierra to San Francisco looking right now?

One-way fares from Santa Cruz de la Sierra to San Francisco are currently higher than usual. Average one-way flight prices are about $782, which is 31% above the typical average for this route.

What is the time difference between Santa Cruz de la Sierra and San Francisco?

San Francisco is 4 hours behind Santa Cruz de la Sierra (Pacific Time vs Bolivia Time). Plan for the time shift when scheduling connections or first-day activities.

What car rental options are available at San Francisco Airport (SFO)?

San Francisco Airport (SFO) hosts 5 major car rental companies, with daily rates averaging $63 for economy cars. Top options include: • Europcar • Thrifty • Dollar • Hertz • Fox

How much should I expect to pay for a Santa Cruz de la Sierra to San Francisco flight?

Round-trip flights from Santa Cruz de la Sierra to San Francisco range from $978 to $1,341, with an average of $1,141 over the past 12 months. Anything below $978 counts as a good deal.

How much is a round-trip flight from Santa Cruz de la Sierra to San Francisco?

Round-trip flights from Santa Cruz de la Sierra to San Francisco typically range from $978 to $1,341. The lowest price found in the past 5 days was $1,003, on United Airlines.

What's the cheapest day of the week to fly from Santa Cruz de la Sierra to San Francisco?

Based on deals KAYAK users found in the last 12 months, Monday is the cheapest day of the week to fly from Santa Cruz de la Sierra to San Francisco. It’s 27% cheaper than the average day, while Sunday is the most expensive, with prices 41% higher.

Which airline is the cheapest to fly from Santa Cruz de la Sierra to San Francisco?

United Airlines ($1,003) and Copa Airlines ($1,005) are the cheapest airlines to fly round-trip from Santa Cruz de la Sierra to San Francisco according to KAYAK data over the last 5 days.

What is the cheapest layover airport when flying from Santa Cruz de la Sierra to San Francisco?

Flights via Panama City Tocumen Intl (PTY) offer the most affordable fares, with an average round-trip price of $1,234. Based on KAYAK data over the past 3 months.

When flying from Santa Cruz de la Sierra to San Francisco which airport offers the shortest layover?

Panama City Tocumen Intl (PTY) had the shortest average connection time for Santa Cruz de la Sierra to San Francisco layovers at 12h 13m over the past 3 months.

$588 CHEAP FLIGHTS from Santa Cruz de la Sierra to San Francisco (VVI - SFO)

Save 26% or more on flights. Compare deals from all over the web.

Never overpay with our price tracking tools.

Filter searches by price, airline and more to find your best flights.

Cheapest round-trip

$1,003

Typical prices: $978-$1,341

United Airlines

Sun 12/23Tue 1/16

VVI - SFO • 2 stops

Cheapest one-way

$578

Typical prices: $536-$664

Copa Airlines

Thu 12/20

VVI - SFO • 1 stop

Nonstop flights

Not available

There are currently no direct flights between Santa Cruz de la Sierra and San Francisco. You'll need to take a connecting flight to reach the destination.

Insights

When to travel

November

Cheapest • 27% price drop

November

Most popular

Good to know

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KAYAK searches 100s of sites at once to find you the best travel deals.

We hope you love your trip to San Francisco!

Flight Deals

Cheap Flights from Santa Cruz de la Sierra to San Francisco (VVI-SFO)

Discover the best prices for you by selecting your travel dates on KAYAK.

Round-trip

One-way

Last minute

Recent round-trip flight deals from Santa Cruz de la Sierra to San Francisco

Wed, Dec 23 - Sat, Jan 16

11:34 am - 1:30 amVVI Santa Cruz de la Sierra Viru Viru Intl-SFO San Francisco

41h 56m2 stops Panama City Tocumen Intl Washington, D.C. Dulles Intl

9:40 pm - 3:44 amSFO San Francisco-VVI Santa Cruz de la Sierra Viru Viru Intl

26h 04m2 stops Newark Panama City Tocumen Intl

$1,003United Airlines

Sat, Dec 19 - Sat, Jan 16

11:34 am - 12:58 amVVI Santa Cruz de la Sierra Viru Viru Intl-SFO San Francisco

17h 24m2 stops Panama City Tocumen Intl Houston George Bush Intcntl

9:40 pm - 3:44 amSFO San Francisco-VVI Santa Cruz de la Sierra Viru Viru Intl

26h 04m2 stops Newark Panama City Tocumen Intl

$1,003United Airlines

Mon, Dec 21 - Sat, Jan 16

11:34 am - 7:35 pmVVI Santa Cruz de la Sierra Viru Viru Intl-SFO San Francisco

36h 01m2 stops Panama City Tocumen Intl Houston George Bush Intcntl

9:40 pm - 3:44 amSFO San Francisco-VVI Santa Cruz de la Sierra Viru Viru Intl

26h 04m2 stops Newark Panama City Tocumen Intl

$1,003United Airlines

Wed, Dec 23 - Fri, Jan 15

11:34 am - 1:30 amVVI Santa Cruz de la Sierra Viru Viru Intl-SFO San Francisco

41h 56m2 stops Panama City Tocumen Intl Washington, D.C. Dulles Intl

6:36 pm - 10:46 pmSFO San Francisco-VVI Santa Cruz de la Sierra Viru Viru Intl

24h 10m2 stops Houston George Bush Intcntl Panama City Tocumen Intl

$1,003United Airlines

Tue, Jan 26 - Fri, Apr 2

11:53 am - 11:15 pmVVI Santa Cruz de la Sierra Viru Viru Intl-SFO San Francisco

15h 22m1 stop Panama City Tocumen Intl

1:22 am - 3:55 amSFO San Francisco-VVI Santa Cruz de la Sierra Viru Viru Intl

23h 33m1 stop Panama City Tocumen Intl

$1,005Copa Airlines

Tue, Jan 26 - Mon, Apr 5

11:53 am - 11:15 pmVVI Santa Cruz de la Sierra Viru Viru Intl-SFO San Francisco

15h 22m1 stop Panama City Tocumen Intl

7:55 pm - 10:00 pmSFO San Francisco-VVI Santa Cruz de la Sierra Viru Viru Intl

23h 05m1 stop Panama City Tocumen Intl

$1,005Copa Airlines

Tue, Dec 22 - Wed, Jan 13

11:34 am - 11:17 pmVVI Santa Cruz de la Sierra Viru Viru Intl-SFO San Francisco

15h 43m1 stop Panama City Tocumen Intl

7:36 pm - 10:46 pmSFO San Francisco-VVI Santa Cruz de la Sierra Viru Viru Intl

23h 10m1 stop Panama City Tocumen Intl

$1,039Copa Airlines

Thu, Jan 28 - Sat, Feb 13

3:45 am - 10:50 amVVI Santa Cruz de la Sierra Viru Viru Intl-SFO San Francisco

35h 05m2 stops Bogotá El Dorado Houston George Bush Intcntl

3:15 pm - 3:43 amSFO San Francisco-VVI Santa Cruz de la Sierra Viru Viru Intl

32h 28m2 stops Newark Panama City Tocumen Intl

$1,048Multiple Airlines

Tue, Dec 22 - Thu, Jan 14

3:45 am - 11:55 amVVI Santa Cruz de la Sierra Viru Viru Intl-SFO San Francisco

36h 10m2 stops Bogotá El Dorado San Salvador El Salvador Intl

1:15 pm - 2:40 amSFO San Francisco-VVI Santa Cruz de la Sierra Viru Viru Intl

33h 25m2 stops San Salvador El Salvador Intl Bogotá El Dorado

$1,092Avianca

Wed, Dec 23 - Tue, Jan 12

3:45 am - 11:55 amVVI Santa Cruz de la Sierra Viru Viru Intl-SFO San Francisco

36h 10m2 stops Bogotá El Dorado San Salvador El Salvador Intl

1:30 am - 2:40 amSFO San Francisco-VVI Santa Cruz de la Sierra Viru Viru Intl

21h 10m2 stops San Salvador El Salvador Intl Bogotá El Dorado

$1,092Avianca

Recent last minute flight deals from Santa Cruz de la Sierra to San Francisco

Sat, Nov 14 - Fri, Nov 27

11:41 am - 12:04 amVVI Santa Cruz de la Sierra Viru Viru Intl-SFO San Francisco

16h 23m2 stops Panama City Tocumen Intl Houston George Bush Intcntl

12:45 am - 10:38 pmSFO San Francisco-VVI Santa Cruz de la Sierra Viru Viru Intl

17h 53m2 stops Houston George Bush Intcntl Panama City Tocumen Intl

$1,109United Airlines

Thu, Nov 12 - Fri, Nov 27

1:08 am - 11:12 pmVVI Santa Cruz de la Sierra Viru Viru Intl-SFO San Francisco

26h 04m1 stop Panama City Tocumen Intl

12:33 am - 10:38 pmSFO San Francisco-VVI Santa Cruz de la Sierra Viru Viru Intl

18h 05m1 stop Panama City Tocumen Intl

$1,177Copa Airlines

Thu, Nov 12 - Fri, Nov 27

3:45 am - 9:29 pmVVI Santa Cruz de la Sierra Viru Viru Intl-SFO San Francisco

21h 44m2 stops Bogotá El Dorado Washington, D.C. Dulles Intl

12:45 am - 10:38 pmSFO San Francisco-VVI Santa Cruz de la Sierra Viru Viru Intl

17h 53m2 stops Houston George Bush Intcntl Panama City Tocumen Intl

$1,196Multiple Airlines

Fri, Nov 13 - Fri, Nov 27

1:08 am - 11:12 pmVVI Santa Cruz de la Sierra Viru Viru Intl-SFO San Francisco

26h 04m1 stop Panama City Tocumen Intl

12:33 am - 10:38 pmSFO San Francisco-VVI Santa Cruz de la Sierra Viru Viru Intl

18h 05m1 stop Panama City Tocumen Intl

$1,208Copa Airlines

Thu, Nov 12 - Sat, Nov 28

3:45 am - 11:17 amVVI Santa Cruz de la Sierra Viru Viru Intl-SFO San Francisco

35h 32m3 stops Bogotá El Dorado Miami Denver Intl

3:29 pm - 2:40 amSFO San Francisco-VVI Santa Cruz de la Sierra Viru Viru Intl

31h 11m3 stops Las Vegas Harry Reid Intl Miami Bogotá El Dorado

$1,337Multiple Airlines

Thu, Nov 12 - Sat, Nov 28

1:08 am - 11:12 pmVVI Santa Cruz de la Sierra Viru Viru Intl-SFO San Francisco

26h 04m1 stop Panama City Tocumen Intl

5:15 pm - 10:38 pmSFO San Francisco-VVI Santa Cruz de la Sierra Viru Viru Intl

25h 23m2 stops Los Angeles Panama City Tocumen Intl

$1,561Multiple Airlines

Thu, Nov 12 - Sat, Nov 28

3:45 am - 11:55 amVVI Santa Cruz de la Sierra Viru Viru Intl-SFO San Francisco

36h 10m2 stops Bogotá El Dorado San Salvador El Salvador Intl

8:25 am - 2:40 amSFO San Francisco-VVI Santa Cruz de la Sierra Viru Viru Intl

38h 15m3 stops Toronto Pearson Intl Lima J Chavez Intl Bogotá El Dorado

$1,571Multiple Airlines

Sat, Nov 14 - Sat, Nov 28

11:41 am - 11:12 pmVVI Santa Cruz de la Sierra Viru Viru Intl-SFO San Francisco

15h 31m1 stop Panama City Tocumen Intl

7:27 pm - 10:38 pmSFO San Francisco-VVI Santa Cruz de la Sierra Viru Viru Intl

23h 11m2 stops Las Vegas Harry Reid Intl Panama City Tocumen Intl

$1,590Multiple Airlines

Fri, Nov 13 - Sat, Nov 28

3:45 am - 12:20 amVVI Santa Cruz de la Sierra Viru Viru Intl-SFO San Francisco

24h 35m3 stops Bogotá El Dorado Orlando Denver Intl

11:00 pm - 2:40 amSFO San Francisco-VVI Santa Cruz de la Sierra Viru Viru Intl

23h 40m2 stops San Salvador El Salvador Intl Bogotá El Dorado

$1,679Multiple Airlines

Fri, Nov 13 - Sat, Nov 28

3:45 am - 12:20 amVVI Santa Cruz de la Sierra Viru Viru Intl-SFO San Francisco

24h 35m3 stops Bogotá El Dorado Orlando Denver Intl

4:55 pm - 2:40 amSFO San Francisco-VVI Santa Cruz de la Sierra Viru Viru Intl

29h 45m3 stops Vancouver Intl Cancun Bogotá El Dorado

$1,773Multiple Airlines

Booking Insights

Price, demand and travel trends for Santa Cruz de la Sierra to San Francisco flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

Prices

Airlines

Layovers

How much is a round-trip flight from Santa Cruz de la Sierra to San Francisco? This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Santa Cruz de la Sierra to San Francisco departing in december.
What's the cheapest day of the week to fly from Santa Cruz de la Sierra to San Francisco?: Based on deals KAYAK users found in the last 12 months, Monday is the cheapest day of the week to fly from Santa Cruz de la Sierra to San Francisco. It’s 27% cheaper than the average day, while Sunday is the most expensive, with prices 41% higher.

Find deals

Low season	February
High season	November
Cheapest flight	$578

Beat the crowds with an average 89% drop in travelers.

The most popular month to fly with an average 64% increase in travelers.

One-way flight from Santa Cruz de la Sierra to San Francisco

When to book flights from Santa Cruz de la Sierra to San Francisco

Are your dates flexible? Find out the best times to travel from Santa Cruz de la Sierra to San Francisco based on our flight data from the last year. Discover the cheapest month and even day to fly.

Estimated round-trip price

KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

What cabin classes can I book on flights from Santa Cruz de la Sierra to San Francisco?
Only Economy Class is available on flights from Santa Cruz de la Sierra to San Francisco.
How long is a flight from Santa Cruz de la Sierra to San Francisco?
A nonstop flight from Santa Cruz de la Sierra to San Francisco takes 00m, covering 5,414 miles.
Do I need a passport to fly from Santa Cruz de la Sierra to San Francisco?
Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.
How much should I expect to pay for a Santa Cruz de la Sierra to San Francisco flight?
Round-trip flights from Santa Cruz de la Sierra to San Francisco range from $978 to $1,341, with an average of $1,141 over the past 12 months. Anything below $978 counts as a good deal.
Have flight prices from Santa Cruz de la Sierra to San Francisco changed much recently?
Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $1,003 to $3,928. That means the highest observed fare was about 4x higher than the lowest one.
How are flight prices from Santa Cruz de la Sierra to San Francisco looking right now?
One-way fares from Santa Cruz de la Sierra to San Francisco are currently higher than usual. Average one-way flight prices are about $782, which is 31% above the typical average for this route.
What car rental options are available at San Francisco Airport (SFO)?
San Francisco Airport (SFO) hosts 5 major car rental companies, with daily rates averaging $63 for economy cars. Top options include:

• Europcar
• Thrifty
• Dollar
• Hertz
• Fox
Which airports can I use when flying from Santa Cruz de la Sierra to San Francisco?
Flights from Santa Cruz de la Sierra to San Francisco usually depart from Santa Cruz de la Sierra Viru Viru Intl (VVI) and arrive at San Francisco (SFO).
Which airports do connecting flights from Santa Cruz de la Sierra to San Francisco pass through?
Most connecting flights from Santa Cruz de la Sierra to San Francisco pass through Panama City Tocumen Intl (PTY), which handles 100% of one-stop traffic on this route.
Can I save money by using flexible dates for flights from Santa Cruz de la Sierra to San Francisco?
Yes. Flexible dates can save you up to 49% on flights from Santa Cruz de la Sierra to San Francisco. Monday is the cheapest departure day at $837 round-trip on average, while Sunday is the most expensive at $1,613, a difference of $776.

KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.
What is the time difference between Santa Cruz de la Sierra and San Francisco?
San Francisco is 4 hours behind Santa Cruz de la Sierra (Pacific Time vs Bolivia Time). Plan for the time shift when scheduling connections or first-day activities.
What popular places can I visit in San Francisco?
Some of the most popular sights in San Francisco are Fisherman's Wharf, Union Square and Moscone Center. These are among the most viewed places in San Francisco on KAYAK.

If your dates are flexible, aim for a Monday departure and avoid flying on Sunday. On this route, Monday flights average $837, about $776 less than Sunday fares (48% savings) based on the last 12 months.
If you can choose when to travel, plan your Santa Cruz de la Sierra to San Francisco trip for November. Fares historically average $837 round-trip in that month - typically $753 less than the most expensive month, which is January (based on the last 12 months).
If you're arriving late at night and need somewhere to stay, check out these hotels close to San Francisco Airport.

• Grand Hyatt At Sfo

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VVI - SFO

$588 Find Cheap Flights from Santa Cruz de la Sierra to San Francisco - Compare and Save

Everything you should know

Cheap Flights from Santa Cruz de la Sierra to San Francisco (VVI-SFO)

Recent round-trip flight deals from Santa Cruz de la Sierra to San Francisco

Recent one-way flight deals from Santa Cruz de la Sierra to San Francisco

Recent last minute flight deals from Santa Cruz de la Sierra to San Francisco

Price, demand and travel trends for Santa Cruz de la Sierra to San Francisco flights

How much is a round-trip flight from Santa Cruz de la Sierra to San Francisco?

What's the cheapest day of the week to fly from Santa Cruz de la Sierra to San Francisco?

Which airline is the cheapest to fly from Santa Cruz de la Sierra to San Francisco?

What is the cheapest layover airport when flying from Santa Cruz de la Sierra to San Francisco?

When flying from Santa Cruz de la Sierra to San Francisco which airport offers the shortest layover?

Key details for Santa Cruz de la Sierra to San Francisco flights

Low season

High season

Cheapest flight

When to book flights from Santa Cruz de la Sierra to San Francisco

Your Santa Cruz de la Sierra to San Francisco flight questions, answered

Your guide to booking Santa Cruz de la Sierra to San Francisco flights

More options for your flight from Santa Cruz de la Sierra to San Francisco

Complete your trip to San Francisco with a hotel stay or car rental

Information on your arrival and departure airports

Cabin class types available on flights from Santa Cruz de la Sierra to San Francisco

Find direct flights to and from Santa Cruz de la Sierra and San Francisco

Flights from domestic origins to San Francisco

Flights to other popular destinations

Find deals for your return flight