VVI - SFO

$515 Find Cheap Flights from Santa Cruz de la Sierra to San Francisco

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Santa Cruz de la Sierra to San Francisco departing on 4/15. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to San Francisco

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santa Cruz de la Sierra to San Francisco, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santa Cruz de la Sierra to San Francisco, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$978
Overall average: $911
Copa Airlines
Mon 4/20Thu 5/28
VVI - SFO • 2 stops
Cheapest one-way
$515
Multiple Airlines
Wed 4/15
VVI - SFO • 3 stops
Top airlines
Cheapest • from $978 (round-trip)
Best reviews • 7.5 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Santa Cruz de la Sierra and San Francisco. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
When to travel
Cheapest • 47% price drop
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to San Francisco!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Santa Cruz de la Sierra to San Francisco (VVI-SFO)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Santa Cruz de la Sierra to San Francisco that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Santa Cruz de la Sierra to San Francisco

Mon, Apr 20 - Thu, May 28
Copa Airlines Logo
11:48 am - 10:25 am
VVI
-
SFO
25h 37m
2 stops
Copa Airlines Logo
11:59 pm - 3:31 am
SFO
-
VVI
24h 32m
2 stops
$978Copa Airlines
Mon, Apr 20 - Wed, May 27
Copa Airlines Logo
11:48 am - 11:40 pm
VVI
-
SFO
14h 52m
1 stop
Copa Airlines Logo
1:12 am - 10:38 pm
SFO
-
VVI
18h 26m
1 stop
$1,001Copa Airlines
Mon, Apr 20 - Sun, Jul 19
Copa Airlines Logo
11:48 am - 5:13 pm
VVI
-
SFO
32h 25m
2 stops
Copa Airlines Logo
12:45 am - 3:35 am
SFO
-
VVI
23h 50m
2 stops
$1,017Copa Airlines
Thu, Apr 9 - Thu, Nov 26
Copa Airlines Logo
11:48 am - 9:16 am
VVI
-
SFO
24h 28m
2 stops
Copa Airlines Logo
11:05 pm - 3:44 am
SFO
-
VVI
24h 39m
2 stops
$1,023Copa Airlines
Thu, May 7 - Tue, May 26
Copa Airlines Logo
1:12 am - 11:40 pm
VVI
-
SFO
25h 28m
1 stop
Copa Airlines Logo
1:12 am - 10:38 pm
SFO
-
VVI
18h 26m
1 stop
$1,050Copa Airlines
Thu, May 7 - Wed, May 27
Avianca Logo
3:35 am - 10:35 pm
VVI
-
SFO
22h 00m
2 stops
Avianca Logo
11:55 pm - 2:30 am
SFO
-
VVI
23h 35m
2 stops
$1,064Avianca
Mon, Jun 22 - Wed, Jul 8
Copa Airlines Logo
1:12 am - 11:40 pm
VVI
-
SFO
25h 28m
1 stop
Copa Airlines Logo
1:12 am - 10:40 pm
SFO
-
VVI
18h 28m
1 stop
$1,078Copa Airlines
Thu, Apr 9 - Sat, Apr 18
Multiple Airlines Logo
3:35 am - 10:15 am
VVI
-
SFO
33h 40m
3 stops
Multiple Airlines Logo
2:30 am - 4:45 am
SFO
-
VVI
23h 15m
3 stops
$1,127Multiple Airlines
Thu, Apr 9 - Sun, Apr 19
Multiple Airlines Logo
3:35 am - 10:15 am
VVI
-
SFO
33h 40m
3 stops
Multiple Airlines Logo
2:15 pm - 2:30 am
SFO
-
VVI
33h 15m
2 stops
$1,129Multiple Airlines
Thu, May 7 - Wed, May 27
Avianca Logo
3:35 am - 10:35 pm
VVI
-
SFO
22h 00m
3 stops
Avianca Logo
11:55 pm - 2:30 am
SFO
-
VVI
23h 35m
2 stops
$1,131Avianca
Booking Insights

KAYAK's insights & trends for Santa Cruz de la Sierra to San Francisco flights

Get data-powered insights and trends into flights from Santa Cruz de la Sierra to San Francisco to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Santa Cruz de la Sierra to San Francisco?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Santa Cruz de la Sierra to San Francisco, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Santa Cruz de la Sierra to San Francisco is May, where tickets cost $472 (return) on average. On the other hand, the most expensive months are January and June, where the average cost of round-trip tickets is $1,118 and $1,113 respectively.

Good to know

Low seasonFebruary
Cheapest flight$515
Best time to beat the crowds but there is an average 19% increase in price.
Most popular time to fly and prices are also 9% lower on average.
Flight from Santa Cruz de la Sierra to San Francisco

When to book flights from Santa Cruz de la Sierra to San Francisco

Are your dates flexible? Find out the best times to travel from Santa Cruz de la Sierra to San Francisco based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Santa Cruz de la Sierra to San Francisco

  • What is the cheapest flight from Santa Cruz de la Sierra to San Francisco?

    In the last 3 days, the lowest price for a flight from Santa Cruz de la Sierra to San Francisco was $515 for a one-way ticket and $978 for a round-trip.

  • Do I need a passport to fly between Santa Cruz de la Sierra and San Francisco?

    A passport is required to fly from Santa Cruz de la Sierra to San Francisco.

  • Which aircraft models fly most regularly from Santa Cruz de la Sierra to San Francisco?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Santa Cruz de la Sierra to San Francisco?

    Star Alliance is the only airline alliance operating flights between Santa Cruz de la Sierra and San Francisco.

  • Which is the best airline for flights from Santa Cruz de la Sierra to San Francisco, Copa Airlines or United Airlines?

    The two airlines most popular with KAYAK users for flights from Santa Cruz de la Sierra to San Francisco are Copa Airlines and United Airlines. With an average price for the route of $983 and an overall rating of 7.5, Copa Airlines is the most popular choice. United Airlines is also a great choice for the route, with an average price of $837 and an overall rating of 7.4.

  • How does KAYAK find such low prices on flights from Santa Cruz de la Sierra to San Francisco?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Santa Cruz de la Sierra to San Francisco.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Santa Cruz de la Sierra to San Francisco?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to San Francisco from Santa Cruz de la Sierra is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Santa Cruz de la Sierra to San Francisco?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to San Francisco with an airline and back to Santa Cruz de la Sierra with another airline. Booking your flights between Santa Cruz de la Sierra and SFO can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Santa Cruz de la Sierra to San Francisco?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to San Francisco from Santa Cruz de la Sierra up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 3 airlines serving from Santa Cruz de la Sierra to San Francisco

 
See real verified KAYAK customer reviews for airlines flying from Santa Cruz de la Sierra to San Francisco. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Santa Cruz de la Sierra to San Francisco? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.5
Copa AirlinesOverall score based on 1568 reviews
7.8Boarding
7.4Comfort
8.1Crew
6.8Entertainment
6.8Food
Airline reviews

Do not book it’s a scam! They stole $1200 from me

2.0 MediocreTalicia, Mar 2026
PTY - RDU
Read more Copa Airlines reviews

Do not book it’s a scam! They stole $1200 from me

Flight got delayed; had to go through security three times.

Copa staff at PTY and one particular crew member were unhelpful & rude.

Seats were awful. Media should have been included for such a long flight.

A lot things happened in this trip.The fly should be less stress.

Horrible. No TV or any type of entertainment on board. Passwnger listening to/watching stuff on their own phone with no headphones making it noise and uncomfortable for everyone else, little/tiny food portions, old seats, useless wifi (cant access anything). Horrible exlerience especially it was a lomg distance flight with kids.

The flight was good overall. Everything went smoothly, although the landing was a bit rough. Still, it was a pleasant experience

Very strict carry on rules meant most of the plane had to gate check their luggage. As is often the case had things that were broken because of this, but I appreciated not being charged to gate check. Otherwise good flight and great crew once on the plane

Some of the Air hostesses are not that friendly. Need improvement

They were super friendly bumped me up to exit row free of charge, All flight legs were on time

Terrible experience! delay 2 time and say i dont have ticket

Flight attendants were friendly & good service, food sucks, seats uncomfortable, not many Asian movies or shows flying from Hong Kong

Flight attendants had a little attitude. Food tastes no good.

Overall we had a good experience during our flight from San Francisco to Houston.

Good flight. However, when booked flight with United, assumed the layover included by United in San Francisco of 1 hr and 40 minutes was sufficient . Not so and would recommend at least 2 hours or more. Needed to go through US immigration (very long lineups), then pick up bags, take all the way to another terminal, running because we did not have sufficient time. We made the flight because they held the door for us but luggage didn’t follow.

the whole trip was smooth, and as comfortable as flying is these days. flight crew was friendly and very courteous and helpful.

Very poor. The flight was delayed from Toronto because some forget to do there job . I got to my connecting gate in San Francisco 10 minutes before the departure.but this didn’t let me board even though the flight was still there for an other 30 minutes. The the gentleman at the unite airline desk told me that they usually wait for passengers but air Canada called and told them not to we I been rerouted to Manila instead of Hong Kong . In San Francisco they mad me check in my carryon bag . I was told the it will directly go yo ho chi minn cuyt but I was told that by the Vietnams airline desk that’s not there I’m 10 hours behind my scheduled flight and looks like I I’m going without baggage. I don’t have a chance of catching ..

First class ticket gets you a choice of chips or nuts. . Just like economy Southwest. Also no screen in the seats. This is first class???!

Flight arrived 30 min early and bag was waiting at the baggage pickup. United Club HNL was one of the nicest in the system

Mean flight attendant. I wanted to reuse my plastic cup, but he (Matthew) said he can't for safety. I then said "I don't want water then" and he poured me a glass. I hope Matthew gets herpes and spends the rest of his life poor, lonely, and homeless.

Horrible experience with Avianca, they delayed their flight and when we arrived to NYC, AVIANCA took 1 hr y 30 mins to park the airplane and all passenger get off the plane, it made me lost all my trains to get back home and I came back to my place at 3 am instead of 12 am. On the top of that their plane seat are so uncomfortable and is not enough space and killed my legs and knees, Avianca used to be good when it was a Colombian company, now after Brasilian company bought them, their service quality is bad and their flights are delayed and oversold.

only a bag of chips and a bottle of water in business class was served

We found the chairs to be really uncomfortable. It’s also really unacceptable that no form of food or drink is included in a 6+ hour flight

Pros: we leave and arrive on time Cons: the most uncomfortable seats ever. You cant recline at all your seats. No entertainment No TVs flight attendants didn't provide even a glass of water. You have to go to back of the airplane and ask for one. I am Colombian and I remember seeing the flight attendants very neat, elegants which is or was a staple of Avianca.it was one with tennis shoes, no male up, the hair was messy... that was really odd.

We waited for one hour to deboard the plane after landing. That could be better

I handed in my suitcase in perfect condition at SAL Airport. And in MIA Airport I received it with one corner broken and the wheels bent.

I like the crew members they're very friendly. Clean plane. The flight was on time. I dont like the comfort my car seat its better that the plane seats. They charge for everything. This airline was very good. Now it's a low cost airline

I had to go to the boarding counter for them to enter my return flight as it’s not with Avianca. There was a long queue as there were lots of people being called to the counter.

6 hour flight and have to pay for everything 100 dollars to add a carry-on bag is insane

Did not fly with Pakistan International Airlines. Have never flown with Pakistan International Airlines.

Everything you need to know for your flight from Santa Cruz de la Sierra to San Francisco

Information on your arrival and departure airports