VVI - SFO

$556 Find Cheap Flights from Santa Cruz de la Sierra to San Francisco - Compare and Save

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1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$928
Typical prices: $834-$1,257
United Airlines
Sat 10/20Wed 10/24
VVI - SFO • 2 stops
Cheapest one-way
$622
Typical prices: $466-$668
Avianca
Sat 10/6
VVI - SFO • 2 stops
Nonstop flights
Not available
There are currently no direct flights between Santa Cruz de la Sierra and San Francisco. You'll need to take a connecting flight to reach the destination.
Insights
Insights
When to travel
September
Cheapest • 25% price drop
November
Most popular
Good to know
+1
Good to know
+1
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We hope you love your trip to San Francisco!
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Booking Insights
Flight Deals

Cheap Flights from Santa Cruz de la Sierra to San Francisco (VVI-SFO)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Santa Cruz de la Sierra to San Francisco

Tue, Oct 20 - Sat, Oct 24
United Airlines Logo
11:47 am - 9:30 amVVI  Santa Cruz de la Sierra Viru Viru Intl-SFO San Francisco
48h 43m2 stops Panama City Tocumen Intl Houston George Bush Intcntl
United Airlines Logo
1:50 pm - 10:44 pmSFO  San Francisco-VVI Santa Cruz de la Sierra Viru Viru Intl
29h 54m2 stops Washington, D.C. Dulles Intl Panama City Tocumen Intl
$928United Airlines
Tue, Oct 20 - Sat, Oct 24
United Airlines Logo
11:47 am - 8:35 amVVI  Santa Cruz de la Sierra Viru Viru Intl-SFO San Francisco
47h 48m2 stops Panama City Tocumen Intl Houston George Bush Intcntl
United Airlines Logo
11:59 pm - 3:40 amSFO  San Francisco-VVI Santa Cruz de la Sierra Viru Viru Intl
24h 41m2 stops Houston George Bush Intcntl Panama City Tocumen Intl
$951United Airlines
Tue, Oct 20 - Mon, Nov 2
Multiple Airlines Logo
1:12 am - 11:47 pmVVI  Santa Cruz de la Sierra Viru Viru Intl-SFO San Francisco
25h 35m2 stops Panama City Tocumen Intl Houston George Bush Intcntl
Multiple Airlines Logo
11:20 pm - 3:37 amSFO  San Francisco-VVI Santa Cruz de la Sierra Viru Viru Intl
24h 17m2 stops Washington, D.C. Dulles Intl Panama City Tocumen Intl
$960Multiple Airlines
Tue, Oct 20 - Mon, Nov 2
Multiple Airlines Logo
3:35 am - 10:25 pmVVI  Santa Cruz de la Sierra Viru Viru Intl-SFO San Francisco
21h 50m3 stops Bogotá El Dorado Miami Dallas/Fort Worth
Multiple Airlines Logo
12:20 pm - 6:00 pmSFO  San Francisco-VVI Santa Cruz de la Sierra Viru Viru Intl
25h 40m2 stops Denver Intl Miami
$1,051Multiple Airlines
Sun, Nov 22 - Tue, Dec 1
Multiple Airlines Logo
3:45 am - 6:45 pmVVI  Santa Cruz de la Sierra Viru Viru Intl-SFO San Francisco
19h 00m2 stops Bogotá El Dorado Houston George Bush Intcntl
Multiple Airlines Logo
12:15 am - 3:42 amSFO  San Francisco-VVI Santa Cruz de la Sierra Viru Viru Intl
23h 27m2 stops Houston George Bush Intcntl Panama City Tocumen Intl
$1,074Multiple Airlines
Tue, Oct 20 - Mon, Nov 2
Multiple Airlines Logo
3:35 am - 10:25 pmVVI  Santa Cruz de la Sierra Viru Viru Intl-SFO San Francisco
21h 50m3 stops Bogotá El Dorado Miami Dallas/Fort Worth
Multiple Airlines Logo
6:02 am - 6:00 pmSFO  San Francisco-VVI Santa Cruz de la Sierra Viru Viru Intl
31h 58m3 stops Denver Intl Charlotte Douglas Miami
$1,130Multiple Airlines
Mon, Nov 23 - Tue, Dec 1
Copa Airlines Logo
11:41 am - 11:12 pmVVI  Santa Cruz de la Sierra Viru Viru Intl-SFO San Francisco
15h 31m1 stop Panama City Tocumen Intl
Copa Airlines Logo
12:33 am - 3:42 amSFO  San Francisco-VVI Santa Cruz de la Sierra Viru Viru Intl
23h 09m1 stop Panama City Tocumen Intl
$1,307Copa Airlines
Tue, Oct 20 - Sun, Nov 1
Copa Airlines Logo
1:12 am - 6:10 pmVVI  Santa Cruz de la Sierra Viru Viru Intl-SFO San Francisco
19h 58m1 stop Panama City Tocumen Intl
Copa Airlines Logo
12:33 am - 3:37 amSFO  San Francisco-VVI Santa Cruz de la Sierra Viru Viru Intl
23h 04m1 stop Panama City Tocumen Intl
$1,328Copa Airlines
Tue, Oct 20 - Sat, Oct 24
United Airlines Logo
11:47 am - 11:40 pmVVI  Santa Cruz de la Sierra Viru Viru Intl-SFO San Francisco
14h 53m1 stop Panama City Tocumen Intl
United Airlines Logo
9:30 pm - 10:44 pmSFO  San Francisco-VVI Santa Cruz de la Sierra Viru Viru Intl
22h 14m2 stops Washington, D.C. Dulles Intl Panama City Tocumen Intl
$1,644United Airlines
Tue, Oct 20 - Sat, Oct 24
United Airlines Logo
11:47 am - 11:40 pmVVI  Santa Cruz de la Sierra Viru Viru Intl-SFO San Francisco
14h 53m1 stop Panama City Tocumen Intl
United Airlines Logo
11:59 pm - 3:40 amSFO  San Francisco-VVI Santa Cruz de la Sierra Viru Viru Intl
24h 41m2 stops Houston George Bush Intcntl Panama City Tocumen Intl
$1,667United Airlines
Booking Insights

Price, demand and travel trends for Santa Cruz de la Sierra to San Francisco flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

How much is a round-trip flight from Santa Cruz de la Sierra to San Francisco?

Round-trip flights from Santa Cruz de la Sierra to San Francisco typically range from $834 to $1,257. The lowest price found in the past 5 days was $928, on United Airlines.

What's the cheapest day of the week to fly from Santa Cruz de la Sierra to San Francisco?

Based on deals KAYAK users found in the last 12 months, Monday is the cheapest day of the week to fly from Santa Cruz de la Sierra to San Francisco. It’s 22% cheaper than the average day, while Friday is the most expensive, with prices 30% higher.

What’s the cheapest month to fly from Santa Cruz de la Sierra to San Francisco?

•September is the cheapest month to fly from Santa Cruz de la Sierra to San Francisco at $805 round-trip.
•June ($1,371) and July ($1,364) are the most expensive months.
•The price difference between flying in the cheapest and most expensive months is 70% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.

Find deals

Key details for Santa Cruz de la Sierra to San Francisco flights

Low season

March

Cheapest flight

$622
Beat the crowds with an average 82% drop in travelers.
The most popular month to fly with an average 115% increase in travelers.
One-way flight from Santa Cruz de la Sierra to San Francisco

When to book flights from Santa Cruz de la Sierra to San Francisco

Are your dates flexible? Find out the best times to travel from Santa Cruz de la Sierra to San Francisco based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Santa Cruz de la Sierra to San Francisco flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines and booking tips.

  • What cabin classes can I book on flights from Santa Cruz de la Sierra to San Francisco?

    Only Economy Class is available on flights from Santa Cruz de la Sierra to San Francisco.

  • How long is a flight from Santa Cruz de la Sierra to San Francisco?

    A nonstop flight from Santa Cruz de la Sierra to San Francisco takes 00m, covering 5,414 miles.

  • Do I need a passport to fly from Santa Cruz de la Sierra to San Francisco?

    Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.

  • How much should I expect to pay for a Santa Cruz de la Sierra to San Francisco flight?

    Round-trip flights from Santa Cruz de la Sierra to San Francisco range from $834 to $1,257, with an average of $1,068 over the past 12 months. Anything below $834 counts as a good deal.

  • Have flight prices from Santa Cruz de la Sierra to San Francisco changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $928 to $2,541. That means the highest observed fare was about 3x higher than the lowest one.

  • How are flight prices from Santa Cruz de la Sierra to San Francisco looking right now?

    One-way fares from Santa Cruz de la Sierra to San Francisco are currently higher than usual. Average one-way flight prices are about $679, which is 13% above the typical average for this route.

  • What car rental options are available at San Francisco Airport (SFO)?

    San Francisco Airport (SFO) hosts 5 major car rental companies, with daily rates starting from around $15 for economy cars. Top options include:

    • Thrifty
    • Europcar
    • Dollar
    • Hertz
    • Fox

  • Which airports can I use when flying from Santa Cruz de la Sierra to San Francisco?

    Flights from Santa Cruz de la Sierra to San Francisco usually depart from Santa Cruz de la Sierra Viru Viru Intl (VVI) and arrive at San Francisco (SFO).

  • Which airports do connecting flights from Santa Cruz de la Sierra to San Francisco pass through?

    Most connecting flights from Santa Cruz de la Sierra to San Francisco pass through Panama City Tocumen Intl (PTY), which handles 100% of one-stop traffic on this route.

  • Can I save money by using flexible dates for flights from Santa Cruz de la Sierra to San Francisco?

    Yes. Flexible dates can save you up to 40% on flights from Santa Cruz de la Sierra to San Francisco. Monday is the cheapest departure day at $837 round-trip on average, while Friday is the most expensive at $1,390, a difference of $553.

    KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • What is the time difference between Santa Cruz de la Sierra and San Francisco?

    San Francisco is 3 hours behind Santa Cruz de la Sierra (Pacific Time vs Bolivia Time). Plan for the time shift when scheduling connections or first-day activities.

  • What popular places can I visit in San Francisco?

    Some of the most popular sights in San Francisco are Fisherman's Wharf, Union Square and Moscone Center. These are among the most viewed places in San Francisco on KAYAK.

Your guide to booking Santa Cruz de la Sierra to San Francisco flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates are flexible, aim for a Monday departure and avoid flying on Friday. On this route, Monday flights average $837, about $553 less than Friday fares (40% savings) based on the last 12 months.
  • If you can choose when to travel, plan your Santa Cruz de la Sierra to San Francisco trip for September. Fares historically average $805 round-trip in that month - typically $566 less than the most expensive month, which is June (based on the last 12 months).
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to San Francisco Airport.

    • Grand Hyatt At Sfo

More options for your flight from Santa Cruz de la Sierra to San Francisco

Complete your trip to San Francisco with a hotel stay or car rental

Car rentals in San Francisco
Hotels in San Francisco
Vacations in San Francisco