SNA - PTY

$282 Find Cheap Flights from Santa Ana to Panama City

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Santa Ana to Panama City departing on 5/21. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
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KAYAK searches hundreds of travel sites at once for deals on flights to Panama City

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santa Ana to Panama City, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santa Ana to Panama City, as well as popular online travel agencies
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Flights Deals

Cheap Flights from Santa Ana to Panama City

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Santa Ana to Panama City that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.

Recent round-trip flight deals from Santa Ana to Panama City

KAYAK's recommended round-trip deals from the most popular airlines that fly from Santa Ana to Panama City.
Discover the best prices for you by selecting your travel dates on KAYAK.
United Airlines Logo
8:15 am - 6:37 pmSNA-PTY
8h 22m1 stop
United Airlines Logo
7:55 am - 8:28 pmPTY-SNA
14h 33m2 stops
$607United Airlines
Find Deal
Tue, Aug 12 - Tue, Aug 19
 Logo
7:58 pm - 2:40 pmSNA-PTY
16h 42m3 stops
 Logo
3:20 am - 10:52 amPTY-SNA
33h 32m3 stops
Tue, May 20 - Sun, May 25
American Airlines Logo
7:02 pm - 2:25 pmSNA-PTY
17h 23m2 stops
American Airlines Logo
1:50 pm - 8:24 amPTY-SNA
20h 34m2 stops
$652American Airlines
Find Deal
Fri, Jun 13 - Fri, Jun 20
United Airlines Logo
7:13 pm - 8:10 pmSNA-PTY
22h 57m1 stop
United Airlines Logo
10:00 am - 10:00 pmPTY-SNA
14h 00m1 stop
$655United Airlines
Find Deal
Sun, Jun 1 - Tue, Jun 10
 Logo
4:27 pm - 2:40 pmSNA-PTY
20h 13m3 stops
 Logo
8:10 pm - 9:17 pmPTY-SNA
27h 07m3 stops
Tue, May 20 - Mon, May 26
 Logo
4:27 pm - 4:30 pmSNA-PTY
46h 03m3 stops
 Logo
3:20 am - 10:52 amPTY-SNA
33h 32m3 stops
Wed, May 21 - Sun, May 25
United Airlines Logo
7:25 am - 8:10 pmSNA-PTY
10h 45m1 stop
United Airlines Logo
3:15 pm - 9:00 amPTY-SNA
19h 45m1 stop
$667United Airlines
Find Deal
Sat, Jun 14 - Sat, Jun 21
 Logo
5:54 pm - 2:45 pmSNA-PTY
18h 51m2 stops
 Logo
3:40 pm - 10:35 amPTY-SNA
20h 55m2 stops
Thu, May 22 - Tue, May 27
American Airlines Logo
1:30 pm - 12:19 pmSNA-PTY
20h 49m2 stops
American Airlines Logo
1:20 pm - 10:01 amPTY-SNA
22h 41m2 stops
$722American Airlines
Find Deal
Wed, May 21 - Wed, May 28
Copa Airlines Logo
7:15 pm - 10:41 amSNA-PTY
13h 26m1 stop
Copa Airlines Logo
12:56 pm - 10:12 pmPTY-SNA
11h 16m1 stop
$4,251Copa Airlines
Find Deal
Thu, May 29 - Mon, Jun 9
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KAYAK's insights & trends for Santa Ana to Panama City flights

Get data-powered insights and trends into flights from Santa Ana to Panama City to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from John Wayne (Santa Ana) to Panama City?

The average price of all round-trip flights from Santa Ana to Panama City clicked on KAYAK for each day over the last 12 months.

When flying from John Wayne (Santa Ana) to Panama City, you should consider leaving on a Tuesday and avoid Fridays if you are looking for the best rates. For your return to John Wayne (Santa Ana), you’ll find the best rates on Tuesdays and the most expensive ones on Mondays.

Good to know

Low seasonSeptember
High seasonJuly
Cheapest flight$282
Best time to beat the crowds with an average 33% drop in price.
Most popular time to fly and prices are also 9% lower on average.
Flight from John Wayne (Santa Ana) to Panama City

When to book flights from Santa Ana to Panama City

Are your dates flexible? Find out the best times to travel from Santa Ana to Panama City based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from John Wayne (Santa Ana) to Panama City

  • What is the cheapest flight from Santa Ana to Panama City?

    In the last 3 days, the lowest price for a flight from Santa Ana to Panama City was $282 for a one-way ticket and $607 for a round-trip.

  • Do I need a passport to fly between John Wayne (Santa Ana) and Panama City?

    Yes

  • Which aircraft models fly most regularly from John Wayne (Santa Ana) to Panama City?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from John Wayne (Santa Ana) to Panama City?

    Star Alliance, and oneworld are the airline alliances operating flights between John Wayne (Santa Ana) and Panama City, with Star Alliance being the most commonly used for this route.

  • Which is the best airline for flights from Santa Ana to Panama City, United Airlines or American Airlines?

    The two airlines most popular with KAYAK users for flights from Santa Ana to Panama City are United Airlines and American Airlines. With an average price for the route of $681 and an overall rating of 7.4, United Airlines is the most popular choice. American Airlines is also a great choice for the route, with an average price of $689 and an overall rating of 7.2.

  • How does KAYAK find such low prices on flights from John Wayne (Santa Ana) to Panama City?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from John Wayne (Santa Ana) to Panama City.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from John Wayne (Santa Ana) to Panama City?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Panama City from John Wayne (Santa Ana) is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from John Wayne (Santa Ana) to Panama City?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Panama City with an airline and back to John Wayne (Santa Ana) with another airline. Booking your flights between John Wayne (Santa Ana) and PTY can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from John Wayne (Santa Ana) to Panama City?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Panama City from John Wayne (Santa Ana) up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Top airlines flying from Santa Ana to Panama City

 
See real verified KAYAK customer reviews for airlines flying from Santa Ana to Panama City. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Santa Ana to Panama City? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
United AirlinesOverall score based on 8696 reviews
6.6Food
7.3Comfort
8.1Crew
7.1Entertainment
7.7Boarding
Airline reviews

Everything is good except the dinner and breakfast. The sandwich is very delicious. Toilet is clean, I only use one of them. Flight attendants are very nice. 👍👍

10.0 ExcellentAnonymous, Apr 2025SFO - HKG
Read more United Airlines reviews

Everything is good except the dinner and breakfast. The sandwich is very delicious. Toilet is clean, I only use one of them. Flight attendants are very nice. 👍👍

The gate was too far away for the connecting flight

Compared with other carriers business class for an overnight was not worth the extra expense.

Seats were comfortable. It’s was so cold and very uncomfortable. I paid 2000 miles for wifi service that was choppy the whole flight. Would like to be reimbursed for my miles Food was so disappointing. Three cold and terrible meals for $3000 round trip. This needs to be better.

Easy to board. Flight was super crowded though so I didn't sleep well on that cross country red-eye flight. The aisles seem ot have gotten narrower and the seat smaller whn luggage and people are getting bigger so it would be AWESOME to have more space and breathing room in general ;)

Pilot Erika DeLong made us feel safe and at ease in a frankly scary time to be flying. Her warm smile and greeting and excellent command of the aircraft in foggy bumpy weather helped us all to calm our nerves and get us home safely.

Plenty of room for me and the cat in Premium Economy. Seat was comfortable. Boarding was a breeze. The lady at the special check-in desk was great, super helpful and professional.

Smooth flight. As always dinner could have been more generous. Breakfast was great.

AWFUL. I have had the experience of traveling with many airlines across the world, and hands down United Airlines is the worst. Not one flight was on time, and I don’t think I met one crew member or staff member who wasn’t rude.

I completely missed my flight because the first leg was longer than planned. I had to sleep overnight in the airport because no accommodation was provided and then sent to Trinidad in the morning with an anticipated 7 hour layover before my flight to Georgetown which was now with Caribbean Airlines. I tried twice with customer service to see if they could put me on an earlier flight which had seats available but was told it wasn’t possible.

Very helpful ground crew after an earlier flight delay and being rebooked on a different flight.

British Airways staff are very polite and willing to help.

The plane was late and then sat on the runway for almost 45 minutes before taking off.

We kept being told that the flight was full and that all overhead compartments were full and therefore had to check in our hand luggage. We were some of the last people to board and noticed that there was still sufficient space in the overhead compartments. We were obliged to check in hand luggage when there was space and so had to wait at luggage retrieval which took a while to then noticed damage to our luggage - not a great experience!

Worst seats I’ve ever had !!! The seats were very narrow and uncomfortable and misaligned with the seats in front of mine leading to bottom of the seat in front of mine pressing on my legs for 15.5 hours !

This was an overnight flight. There was no meal service in first class, just a simple snack basket was offered along with beverages. There should have been some type of continental breakfast prior to arrival in PHL. As an Executive Platinum American Airlines Advantage member, I received no name recognition from the first class flight attendant. When disembarking at PHL, the flight attendants were more interested in their cell phones than saying "thank you" to the passengers as they disembarked.

The flight was quick and to the point. The crew just did their job w/o excessive talking and everything was just perfect.

Awkward carry on process. Forced to check all carry on. No overhead space of worthiness. Left delayed, but made up the time. Crew was amicable.

Amazingly comfy flight - I had upgraded for a reasonable price and it was worth it. The food also was good.

Had to wait on pilot and crew to depart and had to wait to arrive at the gate because they only had 2 crews working. Delays, delays....Planes just keep getting smaller and tighter and they nickle and dime for everything. When will an airline actually wake up and make flying more enjoyable?

Everything you need to know for your flight from Santa Ana to Panama City

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