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Find cheap flights from John Wayne (Santa Ana) to Florida Keys from $82

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Santa Ana to Florida Keys departing on 6/5. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
0 bags
Fri 6/7
Fri 6/14

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Best Florida Keys Flight Deals

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours

Miami
Miami1 stop$287
Key West
Key West2 stops$285

Good to know

Low season

October

High season

March

Cheapest flight

$82
Best time to beat the crowds with an average 16% drop in price.
Most popular time to fly with an average 14% increase in price.
Flight from Santa Ana to Miami

FAQs - booking Florida Keys flights

  • How does KAYAK find such low prices on flights from John Wayne (Santa Ana) to Florida Keys?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from John Wayne (Santa Ana) to Florida Keys.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from John Wayne (Santa Ana) to Florida Keys?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Florida Keys from John Wayne (Santa Ana) is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from John Wayne (Santa Ana) to Florida Keys?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Florida Keys with an airline and back to John Wayne (Santa Ana) with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from John Wayne (Santa Ana) to Florida Keys?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Florida Keys from John Wayne (Santa Ana) up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

See more FAQs

Top tips for finding cheap flights to Florida Keys

  • Looking for a cheap flight? 25% of our users found tickets from John Wayne (Santa Ana) to the following destinations at these prices or less: Miami $307 one-way - $519 round-trip

Top 5 airlines serving from Santa Ana to Florida Keys

 
Need help choosing which airline to fly with from Santa Ana to Florida Keys? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
DeltaOverall score based on 10810 reviews
7.4Food
8.2Boarding
8.0Entertainment
8.6Crew
7.9Comfort
Airline reviews

I would fly again the whole experience was great. The only feed back I can give that they don't do that American Airlines does is the crew there is more humorous with boarding and thank their passengers. It makes it more fun to fly with them. I would however fly Delta again.

10.0 ExcellentDonnel, Apr 2024ATL - EYW
Read more about Delta reviews

I would fly again the whole experience was great. The only feed back I can give that they don't do that American Airlines does is the crew there is more humorous with boarding and thank their passengers. It makes it more fun to fly with them. I would however fly Delta again.

Horrible. This was not first class. This was a connecting flight whi h was late. My original flight never came. I hated the fact that delta gave me a connecting flight from New York to Orlando Florida. No meals and the television screens were not working. There wasn't even any power to charge your phones. This is NOT FIRST CLASS DELTA!!! Do better next time!

They did a fine job. Can't wait to use Delta in the future.

Seat back monitors and outlets were dead and not working.

The experience was good and the flight departed on time and landed early

The flight was delayed but we got to our final destination.

public website still broken for years randomly blocking browsers with privacy options active after loading a page maybe once. check-in on laptop was almost impossible but eventually randomly worked. had to print pass at airport since couldn't get back in to load digital pass on mobile firefox or chrome. red eye flight so smooth onboarding, plenty of room to spread out, easy offboarding. onboard wifi instructions mention vpn can cause problems connecting but fails to also mention private dns. no printed or built in menu list, seems weird to require personal device to point at qr code link for menu which does not even allow direct ordering. people with health condition risk related dietary restrictions trying to avoid for example cholesterol and sugar are left guessing what they can order either way without nutritional info highlights (cranberry juice was minute maid cocktail with as much suger as typical can of soda). tap to pay wasn't working and always seems sketchy to manually enter card info. good movie variety, so limited tv was okay.

Boarding super slow with people allowed to linger in aisles

There were choices for the snacks. Good choices and tasty lunch and breakfast as well.

First time travel in economy and the worst experience I ever had ! Shame on paying 600 dollars to be in a tuna can ! Service was terrible no even water no even class no even matters your flight attendants were lazy and sloppy very bad experience! After all these years traveling in first and once I try this cause I need to go to a destination for an emergency wow shame on you !

Terrible. Flight was cancelled due to the weather in the east and sout east(florida). Did not get any compesation of any kind. According to them, it was not under their control so I lost all the money paid for the 2 fairs from Raleigh, NC to Orlando, Fl.

There were multiple delays but JetBlue tried to make the boarding and departure process as quick and efficient as possible. The crew was as detached from reality as could be, meaning: not very friendly and just doing things by the numbers.

40 minute delay before take off after boarding flight. Bright lights throughout night flight due Issues with light panels. In flight Entertainment nonfunctional

Another horrible Jet Blue experience. This airline has suffered the biggest decline of all from best to worst. TVs didn’t work (again). internet was temperamental. Boarded late and couldn’t get organized to serve snacks.

I hate their constant delays! It’s as if I cannot confidently make plans for timing when I'm traveling with them. I slept through it, so all I can say is it was good.

Did not wait long for wheelchair and attendant to arrive after checking in. Wheeled down to plane Was greeted with a smile when entering the plane Choice of snacks was very limited to 2 items. Seats are uncomfortable. My butt was sore after the 1st hour of flying. Needs better cushioning at seats.

Did not wait long for wheelchair and attendant to arrive after checking in. Wheeled down to plane Was greeted with a smile when entering the plane Choice of snacks was very limited to 2 items.

One hour delayed departure resulted in problems with planned ground transportation at my destination.

No WiFi No TV Bag of chips I guess it could be worse.

I really liked the way snacks and drinks were available throughout the flight!!! The flight attendants were also all fantastic!

I paid $380 for my one-way ticket from California to Minnesota. The fair did not include online check-in. I received instructions from their app to check in at a kiosk. At the kiosk, the boarding pass would not print until an actual person came to verify that I had a personal item and not a carry-on item, On the plane, the person next to me was drunk and allowed to continue to order alcohol. United is garbage I’d rather fly spirit.

Do not like the feeling of being in the basic economy. Everyone should feel good no matter what.

Terrible! The plane was old and you are required to connect your own device to their Wi-Fi rather than have entertainment options in the back of the seat in front of you. The Wi-Fi went out during the flight and there was only one plug for the devices every two seats. Three out of five surrounding my family did not work. The seats and spaces under them were so small I could not fit my backpack, which I’ve always brought on flights and fit before no problem. The crew were unpleasant and patronizing.

There was a group of school age passengers that were very loud and unruly with their chaperones were no where to be found.

Due to one crew member not showing up to work, our flight was significantly delayed causing us to miss our connecting flight in Houston to Mississippi causing us to be delayed by more than 6 hours and missing our event all together. Very disappointing. All because ONE crew member called in sick. United did grant us a $15 meal voucher, which was a small but appreciated concession that I wasn’t able to use because I ordered my lunch and paid for it before applying the concession, and the staff said it was too late to use it. Ugh! We also had a TWO delay coming back from Mississippi, but that was on American Airlines and it was due to weather, so not their fault. Anyway, not at all impressed with United’s handling of our flight and the HUGE disappointment of missing our important family event for our 90 year old mother. All that money and all that stress and emotions for nothing. Having to wait the hour to bring an employee from LAX seemed like something that should not have happened. Why don’t you have a local back-up? Santa Ana is not a little airport in a rural area.

flight delays, staff only communicating when pushed, food service lasting a grand total of 7 minutes, stuck in seat from 45mins into flight until landing

Crew was great and did their best to make us comfortable and captain came out at the beginning to announce why the flight was delayed, weather situation up ahead, and kept us updated throughout the flight.

I liked everything about the flight. The service was excellent!

Delayed a day due to snow storm. Was upgraded. That kind of made up for significant delays from FLL to COS with no compensation or acknowledgement.

the head jack on my seat didn't work and the power outlet didn't work for my seat

Flight was cancelled had to move to another gate late again no internet paid for the month and never can use it waste of money

Flight delayed over an over all day until it cancelled at 1:30am. Would not repeatedly delay that late. Offer hotel rooms and rebook early. Very difficult for families with small children

It was a good flight. Of course it was full, but it went well.

We sat on the plane for 1 hour because the airline was short handed could not be unloading.

We are gluten free, there were not any available complimentary gluten free options.

Flight delayed 3 times. We were directed to go to a gate across from our gate. The plane wasn't there yet so we had to wait for it to arrive, then deplane everyone and then wait again for the plane to be cleaned. After 45 minuites we were allowed on the plane. The first plane had mechanical issues. The 2nd plane must have had bathroom issues because we did not have any food service whatsoever. No snack or beverage. That made for a long time not to have anything considering that we had just made it to the original gate and we had no time to stop to get food or a drink. Then we didn't want to leave the gate to get food because we wouldn't know how much longer the delay would be. Then the next gate change. Had we been told that the total time would have been aprox 45 min later we would have left to get food and a beverage. We had to wait again for the okay to the pilot to take off so we were on the runway for another 20 min. Overall, we were delayed over 2 hours which felt like 4 hours.

Lots of weather delays that were poorly communicated and managed. I get there are weather delays but they didn’t make it clear what was happening or comfortable on the plane

Me and my husband experienced very bad in American Airlines. We missed our flight going to Doha. The American Airlines was delayed we arrived already 10:27pm. Supposed to be 9:40 pm. So what they did they rebooked our flight and they gave us a hotel. When we arrived at the hotel the front desk said it was fully booked already. Oh my gosh! I said why did you accept the booking if it's fully booked. The guy said that's American Airlines they just book even it's already full. That's 2am already, we have nothing to do so, we decided to go another hotel. We pay the room, food and taxi. Pls give an action on this matter. Refund our expenses and give us more compensation. Not only our room, food, taxi but also our efforts, tiredness looking for a room that can accommodate us.

Horrible. Flight was delayed and very bumpy. I was super unhappy

No meal on a cross country flight? SFO-MiA is pretty much the definition of a coast to coast flight. No meal provided. Sky high wi-fi rates too. Stop nickel and diming your customers.

Terrible… missed our flight due to ridiculously long time to go thru baggage check-in!

Everything was really good but the seats are not very comfortable.

Spirit canceled the flight in March and never notified me!

Pretty good. Would’ve been excellent if we would have left on time and the crew wasn’t late.

Spirit airline tries to screw you at every opportunity. Spirit wanted 65$ for an extra pound in the suitcase Made me open the suitcase at the counter to remove 1 pound. Staff very cold and rude Will never fly spirit again and will recommend same to family and friends

The weight limit per bag was really low - 40 lbs - so we had to pay extra. Then, they said their carry on size was 14x18x8, and we measured our bag very carefully. It was within the limit, yet they said it was too big, so we ended up paying an extra $100 for that too!! So it wasn’t the cheap flight we thought it would be. Then, they moved up our initial flight to depart 3 hours earlier which meant we had to be out on the road by 7 am and then have a 6 hour layover and we got home at 2am. It was a grueling day. I won’t be flying with them again.

Overall it was a good experience. Stewards were very kind and professional. The departure and arrival times were as promised. Plane was clean.

Terrible as usual!!!! Very unprofessional and rude flight attendants! You get what you pay for! HORRIBLE

My experience was above excellent!!!! First the lady that pushed me in the wheelchair to the gate was outstanding!!! Then the ladies at the gate went over and beyond, by helping me fill out the immigration form! I would not have been able to get to Guatemala without their help!!! God bless them all! They were amazing 🙏❤️🙏

First....my trip was from Ft. Myers to Philly (not the other way around). Plane was clean, staff was friendly and flight was efficient with boarding and flight time. Thumbs up all around.

Book cheap flights from John Wayne (Santa Ana) to Florida Keys

Recent round-trip flight deals

9/12Thu
2 stopsAmerican Airlines
12h 41mSNA-EYW
9/18Wed
1 stopAmerican Airlines
7h 37mEYW-SNA
$285
7/7Sun
1 stopSpirit Airlines
19h 01mSNA-MIA
7/16Tue
1 stopSpirit Airlines
7h 37mMIA-SNA
$287
9/12Thu
2 stopsAmerican Airlines
12h 41mSNA-EYW
9/18Wed
2 stopsAmerican Airlines
11h 14mEYW-SNA
$290
6/14Fri
1 stopSpirit Airlines
7h 06mSNA-MIA
6/17Mon
1 stopSpirit Airlines
23h 00mMIA-SNA
$290
6/7Fri
1 stopFrontier
11h 33mSNA-MIA
6/13Thu
1 stopFrontier
13h 25mMIA-SNA
$294
7/6Sat
1 stopFrontier
7h 47mSNA-MIA
7/27Sat
1 stopFrontier
13h 30mMIA-SNA
$309
8/17Sat
1 stopDelta
9h 51mSNA-EYW
8/21Wed
1 stopDelta
10h 28mEYW-SNA
$370
8/17Sat
1 stopDelta
9h 51mSNA-EYW
8/21Wed
1 stopDelta
10h 28mEYW-SNA
$470
5/25Sat
1 stopUnited Airlines
7h 25mSNA-MIA
5/29Wed
2 stopsUnited Airlines
12h 42mMIA-SNA
$504
7/31Wed
1 stopUnited Airlines
7h 34mSNA-MIA
8/7Wed
1 stopUnited Airlines
16h 41mMIA-SNA
$524

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Recent one-way flight deals

6/5Wed
1 stopSpirit Airlines
7h 06mSNA-MIA
$82
6/5Wed
1 stopFrontier
8h 47mSNA-MIA
$90
5/16Thu
2 stops
25h 08mSNA-MIA
$192
5/24Fri
2 stops
26h 08mSNA-MIA
$222
5/27Mon
1 stopDelta
8h 35mSNA-MIA
$285
5/13Mon
1 stopDelta
7h 11mSNA-MIA
$290
5/30Thu
nonstopAmerican Airlines
5h 02mSNA-MIA
$314
6/13Thu
nonstopAmerican Airlines
5h 07mSNA-MIA
$323
5/17Fri
1 stopUnited Airlines
18h 54mSNA-MIA
$324
6/12Wed
2 stopsUnited Airlines
17h 33mSNA-MIA
$332

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Last minute flights from Santa Ana to Florida Keys

Last minute flight, train and bus deals

5/13Mon
multi-stopSpirit Airlines
20h 02mSNA-MIA
5/31Fri
multi-stopSpirit Airlines
21h 50mMIA-SNA
$235
5/13Mon
multi-stopSpirit Airlines
22h 06mSNA-MIA
5/31Fri
multi-stopSpirit Airlines
7h 20mMIA-SNA
$238
5/13Mon
multi-stopSpirit Airlines
20h 02mSNA-MIA
5/31Fri
multi-stopSpirit Airlines
31h 18mMIA-SNA
$246
5/13Mon
multi-stop
22h 06mSNA-MIA
5/14Tue
multi-stop
20h 22mMIA-SNA
$336
5/12Sun
multi-stop
29h 33mSNA-MIA
5/18Sat
multi-stop
30h 57mMIA-SNA
$364
5/11Sat
multi-stopDelta
9h 00mSNA-MIA
5/15Wed
multi-stopDelta
7h 52mMIA-SNA
$525
5/13Mon
nonstopAmerican Airlines
5h 02mSNA-MIA
5/31Fri
nonstopAmerican Airlines
5h 44mMIA-SNA
$548
5/13Mon
nonstopAmerican Airlines
5h 02mSNA-MIA
5/31Fri
multi-stopAmerican Airlines
9h 43mMIA-SNA
$556
5/11Sat
multi-stopUnited Airlines
7h 52mSNA-MIA
5/15Wed
multi-stopUnited Airlines
8h 13mMIA-SNA
$558
5/11Sat
multi-stopUnited Airlines
6h 38mSNA-MIA
5/15Wed
multi-stopUnited Airlines
13h 50mMIA-SNA
$563

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Santa Ana - Florida Keys Flights

Departure:

John Wayne (Santa Ana) (SNA)United States

Return flight deals:

Florida Keys - John Wayne (Santa Ana)

Cabin classes:

$382
$416
$169
$59