SNA - GSP

$185 Find Cheap Flights from John Wayne (Santa Ana) to Greenville - Compare and Save

1 adult
1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$435
Typical prices: $457-$622
Delta
Sat 10/6Wed 10/10
SNA - GSP • 1 stop
Cheapest one-way
$218
Typical prices: $259-$549
United Airlines
Sat 11/17
SNA - GSP • 1 stop
Nonstop flights
Not available
There are currently no direct flights between Santa Ana and Greenville. You'll need to take a connecting flight to reach the destination.
Insights
Insights
When to travel
May
Cheapest • 25% price drop
June
Most popular
Good to know
+1
Good to know
+1
Top layover airports
Atlanta Hartsfield-Jackson (ATL)
Cheapest • Avg $446 (round-trip)
Dallas/Fort Worth (DFW)
Shortest trip • 7h 20m (one-way)
Insights
Insights
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Booking Insights
Flight Deals

Cheap Flights from Santa Ana to Greenville (SNA-GSP)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Santa Ana to Greenville

Fri, Nov 13 - Mon, Nov 16
United Airlines Logo
9:10 pm - 11:17 amSNA  Santa Ana J. Wayne/Orange Cnty-GSP Greenville
11h 07m1 stop Newark
United Airlines Logo
4:29 pm - 9:19 pmGSP  Greenville-SNA Santa Ana J. Wayne/Orange Cnty
7h 50m1 stop Denver Intl
$435United Airlines
Tue, Sep 22 - Tue, Sep 29
United Airlines Logo
10:33 am - 9:18 pmSNA  Santa Ana J. Wayne/Orange Cnty-GSP Greenville
7h 45m1 stop Chicago O'Hare Intl
United Airlines Logo
7:00 am - 2:03 pmGSP  Greenville-SNA Santa Ana J. Wayne/Orange Cnty
10h 03m1 stop Houston George Bush Intcntl
$435United Airlines
Wed, Oct 7 - Tue, Oct 13
American Airlines Logo
10:42 am - 10:05 pmSNA  Santa Ana J. Wayne/Orange Cnty-GSP Greenville
8h 23m1 stop Dallas/Fort Worth
American Airlines Logo
5:25 pm - 10:29 pmGSP  Greenville-SNA Santa Ana J. Wayne/Orange Cnty
8h 04m1 stop Dallas/Fort Worth
$435American Airlines
Tue, Oct 6 - Sat, Oct 10
Delta Logo
6:45 am - 6:09 pmSNA  Santa Ana J. Wayne/Orange Cnty-GSP Greenville
8h 24m1 stop Atlanta Hartsfield-Jackson
Delta Logo
7:00 am - 12:44 pmGSP  Greenville-SNA Santa Ana J. Wayne/Orange Cnty
8h 44m1 stop Atlanta Hartsfield-Jackson
$435Delta
Mon, Oct 19 - Fri, Oct 23
United Airlines Logo
9:00 pm - 10:45 amSNA  Santa Ana J. Wayne/Orange Cnty-GSP Greenville
10h 45m1 stop Newark
United Airlines Logo
5:46 pm - 10:26 pmGSP  Greenville-SNA Santa Ana J. Wayne/Orange Cnty
7h 40m1 stop Chicago O'Hare Intl
$435United Airlines
Sat, Oct 3 - Wed, Oct 14
American Airlines Logo
6:45 am - 6:59 pmSNA  Santa Ana J. Wayne/Orange Cnty-GSP Greenville
9h 14m1 stop Charlotte Douglas
American Airlines Logo
5:25 pm - 10:29 pmGSP  Greenville-SNA Santa Ana J. Wayne/Orange Cnty
8h 04m1 stop Dallas/Fort Worth
$444American Airlines
Fri, Nov 13 - Mon, Nov 16
Southwest Logo
8:15 am - 8:10 pmSNA  Santa Ana J. Wayne/Orange Cnty-GSP Greenville
8h 55m2 stops San Jose Nashville Intl
Southwest Logo
7:05 am - 2:00 pmGSP  Greenville-SNA Santa Ana J. Wayne/Orange Cnty
9h 55m2 stops Nashville Intl Denver Intl
$526Southwest
Mon, Dec 28 - Wed, Jan 6
Delta Logo
2:10 pm - 11:59 pmSNA  Santa Ana J. Wayne/Orange Cnty-GSP Greenville
6h 49m1 stop Atlanta Hartsfield-Jackson
Delta Logo
6:00 am - 12:56 pmGSP  Greenville-SNA Santa Ana J. Wayne/Orange Cnty
9h 56m1 stop Atlanta Hartsfield-Jackson
$557Delta
Mon, Dec 28 - Tue, Jan 5
Delta Logo
2:10 pm - 11:59 pmSNA  Santa Ana J. Wayne/Orange Cnty-GSP Greenville
6h 49m1 stop Atlanta Hartsfield-Jackson
Delta Logo
6:00 am - 12:56 pmGSP  Greenville-SNA Santa Ana J. Wayne/Orange Cnty
9h 56m1 stop Atlanta Hartsfield-Jackson
$557Delta
Fri, Oct 30 - Mon, Nov 2
Southwest Logo
7:15 am - 8:00 pmSNA  Santa Ana J. Wayne/Orange Cnty-GSP Greenville
9h 45m2 stops Dallas Love Field Nashville Intl
Southwest Logo
6:40 am - 1:35 pmGSP  Greenville-SNA Santa Ana J. Wayne/Orange Cnty
9h 55m2 stops Nashville Intl Denver Intl
$608Southwest
Booking Insights

Price, demand and travel trends for Santa Ana to Greenville flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights from Santa Ana to Greenville with more confidence.

How much is a round-trip flight from Santa Ana to Greenville?

Round-trip flights from Santa Ana to Greenville start at $435. Prices are below average for this route right now, with typical round-trip fares ranging from $457 to $622. The lowest price found in the past 5 days was $435 on Delta.

What's the cheapest day of the week to fly from Santa Ana to Greenville?

Friday is the cheapest day of the week to fly from Santa Ana to Greenville, it is 22% cheaper than the average day. Tuesday is the most expensive day with flight prices 11% higher than average. Based on deals found by KAYAK users in the last 12 months.

What is the cheapest month to fly from Santa Ana to Greenville?

  • May is the cheapest month to fly from Santa Ana to Greenville at $433 round-trip.
  • February ($887) and December ($678) are the most expensive months.
  • The price difference between flying in the cheapest and most expensive months is 104% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.

Find deals

Key details for Santa Ana to Greenville flights

Low season

March

Cheapest flight

$218
Best time to beat the crowds but there is an average 1% increase in price.
Most popular time to fly with an average 7% increase in price.
Flight from Santa Ana to Greenville

When to book flights from Santa Ana to Greenville

Are your dates flexible? Find out the best times to travel from Santa Ana to Greenville based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Santa Ana to Greenville flight questions, answered

Find helpful route details based on KAYAK data, including flight times, airports, airlines and booking questions.

  • Which airports can I use when flying from Santa Ana to Greenville?

    Flights from Santa Ana to Greenville usually depart from Santa Ana J. Wayne/Orange Cnty (SNA) and arrive at Greenville (GSP).

  • What cabin classes can I book on flights from Santa Ana to Greenville?

    Two cabin classes are available on flights from Santa Ana to Greenville:

    • Economy Class
    • First Class

  • Which airports do connecting flights from Santa Ana to Greenville pass through?

    One-stop flights from Santa Ana to Greenville most commonly connect through:

    • Dallas/Fort Worth (DFW) - 64% of one-stop connections
    • Atlanta Hartsfield-Jackson (ATL) - 19% of one-stop connections
    • Chicago O'Hare Intl (ORD) - 11% of one-stop connections
    • Charlotte Douglas (CLT) - 6% of one-stop connections

    Dallas/Fort Worth (DFW) handles the largest share of one-stop connections on this route.

  • Can I save money by using flexible dates for flights from Santa Ana to Greenville?

    Yes. Being flexible with your travel dates can save you up to 30% on the Santa Ana to Greenville route. Friday is the cheapest departure day at $452 round-trip on average, while Tuesday is the most expensive at $643, a difference of $191. KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • How long is a flight from Santa Ana to Greenville?

    A nonstop flight from Santa Ana to Greenville takes 0h 00m, covering 2,025 miles.

  • Do I need a passport to fly from Santa Ana to Greenville?

    No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID, or another TSA-accepted form of identification.

  • Have flight prices from Santa Ana to Greenville changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $435 to $2,278. That means the highest observed fare was about 5x higher than the lowest one.

  • How are flight prices from Santa Ana to Greenville looking right now?

    One-way fares from Santa Ana to Greenville are currently in line with typical prices for this route. Average one-way fares are about $369.

  • How much time can I save by choosing a different layover airport from Santa Ana to Greenville?

    Flying via Dallas/Fort Worth (DFW) gives the shortest average 1-stop total travel time at 7h 20m, compared with 7h 38m via Atlanta Hartsfield-Jackson (ATL) and 7h 55m via Chicago O'Hare Intl (ORD).

  • What is the time difference between Santa Ana and Greenville?

    Greenville is 3 hours ahead of Santa Ana (Eastern Time vs Pacific Time). Plan for the time shift when scheduling connections or first-day activities.

  • What car rental options are available at Greenville Airport (GSP)?

    Greenville Airport (GSP) hosts 5 major car rental companies, with daily rates starting from around $30 for economy cars. Top options include:
    · Budget
    · Alamo
    · Thrifty
    · Enterprise Rent-A-Car
    · Avis

  • How much should I expect to pay for a Santa Ana to Greenville flight?

    Round-trip flights from Santa Ana to Greenville range from $457 to $622, with an average of $579 over the past 12 months. Anything below $457 counts as a good deal.

Your guide to booking Santa Ana to Greenville flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates can be flexible, aim for a Friday departure instead of Tuesday. On this route, Friday flights average $452 - about $191 less than Tuesday (30% savings) based on the last 12 months.
  • If you can choose when to travel, plan your Santa Ana to Greenville trip for May. Fares historically average $433 round-trip in that month - typically $454 less than the most expensive month, which is February (based on the last 12 months).

Everything you need to know for your flight from Santa Ana to Greenville

Information on your arrival and departure airports

John Wayne (Santa Ana) (SNA)
Greenville (GSP)