Which airports can I use when flying from Santa Ana to Greenville?

Flights from Santa Ana to Greenville usually depart from Santa Ana J. Wayne/Orange Cnty (SNA) and arrive at Greenville (GSP).

What cabin classes can I book on flights from Santa Ana to Greenville?

Two cabin classes are available on flights from Santa Ana to Greenville: • Economy Class • First Class

Which airports do connecting flights from Santa Ana to Greenville pass through?

One-stop flights from Santa Ana to Greenville most commonly connect through: • Dallas/Fort Worth (DFW) - 65% of one-stop connections • Atlanta Hartsfield-Jackson (ATL) - 18% of one-stop connections • Chicago O'Hare Intl (ORD) - 10% of one-stop connections • Charlotte Douglas (CLT) - 6% of one-stop connections

Can I save money by using flexible dates for flights from Santa Ana to Greenville?

Yes. Flexible dates can save you up to 30% on flights from Santa Ana to Greenville. Friday is the cheapest departure day at $452 round-trip on average, while Tuesday is the most expensive at $643, a difference of $191. KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

How long is a flight from Santa Ana to Greenville?

A nonstop flight from Santa Ana to Greenville takes 00m, covering 2,025 miles.

Do I need a passport to fly from Santa Ana to Greenville?

No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID or another TSA-accepted form of identification.

Have flight prices from Santa Ana to Greenville changed much recently?

Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $369 to $2,829. That means the highest observed fare was about 8x higher than the lowest one.

How are flight prices from Santa Ana to Greenville looking right now?

One-way fares from Santa Ana to Greenville are currently lower than usual. Average one-way flight prices are about $186, which is 48% below the typical average for this route.

How much time can I save by choosing a different layover airport from Santa Ana to Greenville?

Flying via Dallas/Fort Worth (DFW) gives the shortest average 1-stop total travel time at 7h 19m, compared with 7h 32m via Atlanta Hartsfield-Jackson (ATL) and 7h 55m via Chicago O'Hare Intl (ORD).

What is the time difference between Santa Ana and Greenville?

Greenville is 3 hours ahead of Santa Ana (Eastern Time vs Pacific Time). Plan for the time shift when scheduling connections or first-day activities.

What car rental options are available at Greenville Airport (GSP)?

Greenville Airport (GSP) hosts 5 major car rental companies, with daily rates starting from around $30 for economy cars. Top options include: • Budget • Alamo • Thrifty • Enterprise Rent-A-Car • Avis

How much should I expect to pay for a Santa Ana to Greenville flight?

Round-trip flights from Santa Ana to Greenville range from $457 to $622, with an average of $579 over the past 12 months. Anything below $457 counts as a good deal.

How much is a round-trip flight from Santa Ana to Greenville?

Round-trip flights from Santa Ana to Greenville typically range from $457 to $622. The lowest price found in the past 5 days was $369, on American Airlines.

What's the cheapest day of the week to fly from Santa Ana to Greenville?

Based on deals KAYAK users found in the last 12 months, Friday is the cheapest day of the week to fly from Santa Ana to Greenville. It’s 22% cheaper than the average day, while Tuesday is the most expensive, with prices 11% higher.

What’s the cheapest month to fly from Santa Ana to Greenville?

•May is the cheapest month to fly from Santa Ana to Greenville at $433 round-trip. •February ($887) and December ($678) are the most expensive months. •The price difference between flying in the cheapest and most expensive months is 104% on average. This is based on KAYAK aggregated and averaged internal data over the past 12 months.

Which airline is the cheapest to fly from Santa Ana to Greenville?

American Airlines ($369) and United Airlines ($369) are the cheapest airlines to fly round-trip from Santa Ana to Greenville according to KAYAK data over the last 5 days.

What’s the most popular layover airport when flying from Santa Ana to Greenville?

Dallas/Fort Worth (DFW) is the most popular layover for the Santa Ana to Greenville route. 65% of KAYAK users who booked 1-stop round-trips over the past 3 months connected via DFW.

What is the cheapest layover airport when flying from Santa Ana to Greenville?

Flights via Atlanta Hartsfield-Jackson (ATL) offer the most affordable fares, with an average round-trip price of $496. Based on KAYAK data over the past 3 months.

When flying from Santa Ana to Greenville which airport offers the shortest layover?

Dallas/Fort Worth (DFW) had the shortest average connection time for Santa Ana to Greenville layovers at 4h 19m over the past 3 months.

$173 CHEAP FLIGHTS from John Wayne (Santa Ana) to Greenville (SNA - GSP)

Save 21% or more on flights. Compare deals from all over the web.

Never overpay with our price tracking tools.

Filter searches by price, airline and more to find your best flights.

Cheapest round-trip

$369

Typical prices: $457-$622

American Airlines

Sun 10/21Wed 10/24

SNA - GSP • 1 stop

Cheapest one-way

$173

Typical prices: $259-$549

Multiple Airlines

Tue 11/13

SNA - GSP • 2 stops

Nonstop flights

Not available

There are currently no direct flights between Santa Ana and Greenville. You'll need to take a connecting flight to reach the destination.

Insights

When to travel

May

Cheapest • 25% price drop

June

Most popular

Good to know

Top layover airports

Atlanta Hartsfield-Jackson (ATL)

Cheapest • Avg $496 (round-trip)

Dallas/Fort Worth (DFW)

Shortest trip • 7h 19m (one-way)

Insights

Start a new search

KAYAK searches 100s of sites at once to find you the best travel deals.

We hope you love your trip to Greenville!

Flight Deals

Cheap Flights from Santa Ana to Greenville (SNA-GSP)

Discover the best prices for you by selecting your travel dates on KAYAK.

Round-trip

One-way

Last minute

Recent round-trip flight deals from Santa Ana to Greenville

Wed, Oct 21 - Sat, Oct 24

12:01 pm - 10:05 pmSNA Santa Ana J. Wayne/Orange Cnty-GSP Greenville

7h 04m1 stop Dallas/Fort Worth

3:58 pm - 8:17 pmGSP Greenville-SNA Santa Ana J. Wayne/Orange Cnty

7h 19m1 stop Charlotte Douglas

$369American Airlines

Sat, Nov 14 - Tue, Nov 17

10:47 am - 8:58 pmSNA Santa Ana J. Wayne/Orange Cnty-GSP Greenville

7h 11m1 stop Chicago O'Hare Intl

11:58 am - 8:14 pmGSP Greenville-SNA Santa Ana J. Wayne/Orange Cnty

11h 16m1 stop Newark

$369United Airlines

Sat, Nov 14 - Tue, Nov 17

10:47 am - 8:58 pmSNA Santa Ana J. Wayne/Orange Cnty-GSP Greenville

7h 11m1 stop Chicago O'Hare Intl

10:26 am - 5:33 pmGSP Greenville-SNA Santa Ana J. Wayne/Orange Cnty

10h 07m2 stops Washington, D.C. Dulles Intl Denver Intl

$374United Airlines

Sat, Nov 14 - Tue, Nov 17

7:40 pm - 10:10 amSNA Santa Ana J. Wayne/Orange Cnty-GSP Greenville

11h 30m2 stops Phoenix Sky Harbor Intl Baltimore/Washington

7:05 am - 2:00 pmGSP Greenville-SNA Santa Ana J. Wayne/Orange Cnty

9h 55m2 stops Nashville Intl Denver Intl

$379Southwest

Tue, Dec 1 - Tue, Dec 15

7:45 am - 8:50 pmSNA Santa Ana J. Wayne/Orange Cnty-GSP Greenville

10h 05m2 stops Dallas Love Field Nashville Intl

2:50 pm - 9:45 pmGSP Greenville-SNA Santa Ana J. Wayne/Orange Cnty

9h 55m2 stops Baltimore/Washington Denver Intl

$411Southwest

Wed, Oct 21 - Sat, Oct 24

8:25 am - 9:05 pmSNA Santa Ana J. Wayne/Orange Cnty-GSP Greenville

9h 40m2 stops Las Vegas Harry Reid Intl Nashville Intl

6:40 am - 12:50 pmGSP Greenville-SNA Santa Ana J. Wayne/Orange Cnty

9h 10m2 stops Nashville Intl Phoenix Sky Harbor Intl

$411Southwest

Tue, Dec 1 - Tue, Dec 15

8:49 am - 9:59 pmSNA Santa Ana J. Wayne/Orange Cnty-GSP Greenville

10h 10m1 stop Chicago O'Hare Intl

5:16 pm - 10:17 pmGSP Greenville-SNA Santa Ana J. Wayne/Orange Cnty

8h 01m1 stop Charlotte Douglas

$420American Airlines

Tue, Dec 1 - Tue, Dec 15

9:55 am - 10:03 pmSNA Santa Ana J. Wayne/Orange Cnty-GSP Greenville

9h 08m2 stops Phoenix Sky Harbor Intl Dallas/Fort Worth

5:16 pm - 10:17 pmGSP Greenville-SNA Santa Ana J. Wayne/Orange Cnty

8h 01m1 stop Charlotte Douglas

$425American Airlines

Wed, Oct 21 - Sat, Oct 24

12:01 pm - 10:05 pmSNA Santa Ana J. Wayne/Orange Cnty-GSP Greenville

7h 04m1 stop Dallas/Fort Worth

8:00 am - 3:39 pmGSP Greenville-SNA Santa Ana J. Wayne/Orange Cnty

10h 39m2 stops Dallas/Fort Worth Phoenix Sky Harbor Intl

$425American Airlines

Fri, Oct 23 - Fri, Oct 30

8:00 pm - 9:58 amSNA Santa Ana J. Wayne/Orange Cnty-GSP Greenville

10h 58m2 stops San Francisco Chicago O'Hare Intl

4:29 pm - 9:19 pmGSP Greenville-SNA Santa Ana J. Wayne/Orange Cnty

7h 50m1 stop Denver Intl

$426United Airlines

Recent last minute flight deals from Santa Ana to Greenville

Sat, Oct 3 - Sat, Oct 10

4:35 pm - 1:41 pmSNA Santa Ana J. Wayne/Orange Cnty-GSP Greenville

18h 06m1 stop Dallas/Fort Worth

7:45 pm - 9:52 amGSP Greenville-SNA Santa Ana J. Wayne/Orange Cnty

17h 07m1 stop Dallas/Fort Worth

$919American Airlines

Thu, Oct 8 - Sun, Oct 11

10:42 am - 10:05 pmSNA Santa Ana J. Wayne/Orange Cnty-GSP Greenville

8h 23m1 stop Dallas/Fort Worth

8:00 am - 1:45 pmGSP Greenville-SNA Santa Ana J. Wayne/Orange Cnty

8h 45m1 stop Dallas/Fort Worth

$997American Airlines

Wed, Oct 7 - Sun, Oct 11

6:45 am - 4:35 pmSNA Santa Ana J. Wayne/Orange Cnty-GSP Greenville

6h 50m1 stop Dallas/Fort Worth

8:00 am - 1:45 pmGSP Greenville-SNA Santa Ana J. Wayne/Orange Cnty

8h 45m1 stop Dallas/Fort Worth

$997American Airlines

Wed, Oct 7 - Sun, Oct 11

9:55 am - 9:23 pmSNA Santa Ana J. Wayne/Orange Cnty-GSP Greenville

8h 28m2 stops Phoenix Sky Harbor Intl Charlotte Douglas

8:00 am - 1:45 pmGSP Greenville-SNA Santa Ana J. Wayne/Orange Cnty

8h 45m1 stop Dallas/Fort Worth

$1,002American Airlines

Thu, Oct 8 - Sun, Oct 11

6:45 am - 7:10 pmSNA Santa Ana J. Wayne/Orange Cnty-GSP Greenville

9h 25m1 stop Dallas/Fort Worth

8:00 am - 3:39 pmGSP Greenville-SNA Santa Ana J. Wayne/Orange Cnty

10h 39m2 stops Dallas/Fort Worth Phoenix Sky Harbor Intl

$1,002American Airlines

Thu, Oct 8 - Sun, Oct 11

7:31 pm - 8:24 amSNA Santa Ana J. Wayne/Orange Cnty-GSP Greenville

9h 53m2 stops Phoenix Sky Harbor Intl Charlotte Douglas

8:00 am - 3:39 pmGSP Greenville-SNA Santa Ana J. Wayne/Orange Cnty

10h 39m2 stops Dallas/Fort Worth Phoenix Sky Harbor Intl

$1,007American Airlines

Wed, Oct 7 - Sun, Oct 11

9:55 am - 10:05 pmSNA Santa Ana J. Wayne/Orange Cnty-GSP Greenville

9h 10m2 stops Phoenix Sky Harbor Intl Dallas/Fort Worth

8:00 am - 3:39 pmGSP Greenville-SNA Santa Ana J. Wayne/Orange Cnty

10h 39m2 stops Dallas/Fort Worth Phoenix Sky Harbor Intl

$1,007American Airlines

Sat, Oct 3 - Sat, Oct 10

6:45 am - 8:58 pmSNA Santa Ana J. Wayne/Orange Cnty-GSP Greenville

11h 13m1 stop Chicago O'Hare Intl

6:20 am - 8:51 pmGSP Greenville-SNA Santa Ana J. Wayne/Orange Cnty

17h 31m3 stops Chicago O'Hare Intl Houston George Bush Intcntl San Francisco

$1,077United Airlines

Sat, Oct 3 - Sat, Oct 10

6:22 pm - 9:58 amSNA Santa Ana J. Wayne/Orange Cnty-GSP Greenville

12h 36m2 stops San Francisco Chicago O'Hare Intl

6:20 am - 8:51 pmGSP Greenville-SNA Santa Ana J. Wayne/Orange Cnty

17h 31m3 stops Chicago O'Hare Intl Houston George Bush Intcntl San Francisco

$1,093United Airlines

Thu, Oct 8 - Sun, Oct 11

7:30 am - 6:28 pmSNA Santa Ana J. Wayne/Orange Cnty-GSP Greenville

31h 58m3 stops Las Vegas Harry Reid Intl Richmond Byrd Intl Tampa

10:12 am - 4:15 pmGSP Greenville-SNA Santa Ana J. Wayne/Orange Cnty

33h 03m3 stops Tampa Gulfport Biloxi Regional Las Vegas Harry Reid Intl

$1,588Breeze Airways

Booking Insights

Price, demand and travel trends for Santa Ana to Greenville flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

Prices

Airlines

Layovers

How much is a round-trip flight from Santa Ana to Greenville? This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Santa Ana to Greenville departing in october.
What's the cheapest day of the week to fly from Santa Ana to Greenville?: Based on deals KAYAK users found in the last 12 months, Friday is the cheapest day of the week to fly from Santa Ana to Greenville. It’s 22% cheaper than the average day, while Tuesday is the most expensive, with prices 11% higher.
What’s the cheapest month to fly from Santa Ana to Greenville? KAYAK internal proprietary data takes all prices for each month over the last 12 months for round-trip flights from Santa Ana to Greenville, removes the top 0.1% to account for outliers and then takes the median of all values for each month.: •May is the cheapest month to fly from Santa Ana to Greenville at $433 round-trip.
•February ($887) and December ($678) are the most expensive months.
•The price difference between flying in the cheapest and most expensive months is 104% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.

Find deals

Low season	March
High season	June
Cheapest flight	$173

Beat the crowds with an average 52% drop in travelers.

The most popular month to fly with an average 124% increase in travelers.

One-way flight from Santa Ana to Greenville

When to book flights from Santa Ana to Greenville

Are your dates flexible? Find out the best times to travel from Santa Ana to Greenville based on our flight data from the last year. Discover the cheapest month and even day to fly.

Estimated round-trip price

KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

What cabin classes can I book on flights from Santa Ana to Greenville?
Two cabin classes are available on flights from Santa Ana to Greenville:

• Economy Class
• First Class
How long is a flight from Santa Ana to Greenville?
A nonstop flight from Santa Ana to Greenville takes 00m, covering 2,025 miles.
Do I need a passport to fly from Santa Ana to Greenville?
No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID or another TSA-accepted form of identification.
How much should I expect to pay for a Santa Ana to Greenville flight?
Round-trip flights from Santa Ana to Greenville range from $457 to $622, with an average of $579 over the past 12 months. Anything below $457 counts as a good deal.
Have flight prices from Santa Ana to Greenville changed much recently?
Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $369 to $2,829. That means the highest observed fare was about 8x higher than the lowest one.
How are flight prices from Santa Ana to Greenville looking right now?
One-way fares from Santa Ana to Greenville are currently lower than usual. Average one-way flight prices are about $186, which is 48% below the typical average for this route.
What car rental options are available at Greenville Airport (GSP)?
Greenville Airport (GSP) hosts 5 major car rental companies, with daily rates starting from around $30 for economy cars. Top options include:

• Budget
• Alamo
• Thrifty
• Enterprise Rent-A-Car
• Avis
Which airports can I use when flying from Santa Ana to Greenville?
Flights from Santa Ana to Greenville usually depart from Santa Ana J. Wayne/Orange Cnty (SNA) and arrive at Greenville (GSP).
Which airports do connecting flights from Santa Ana to Greenville pass through?
One-stop flights from Santa Ana to Greenville most commonly connect through:

• Dallas/Fort Worth (DFW) - 65% of one-stop connections
• Atlanta Hartsfield-Jackson (ATL) - 18% of one-stop connections
• Chicago O'Hare Intl (ORD) - 10% of one-stop connections
• Charlotte Douglas (CLT) - 6% of one-stop connections
Can I save money by using flexible dates for flights from Santa Ana to Greenville?
Yes. Flexible dates can save you up to 30% on flights from Santa Ana to Greenville. Friday is the cheapest departure day at $452 round-trip on average, while Tuesday is the most expensive at $643, a difference of $191.

KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.
How much time can I save by choosing a different layover airport from Santa Ana to Greenville?
Flying via Dallas/Fort Worth (DFW) gives the shortest average 1-stop total travel time at 7h 19m, compared with 7h 32m via Atlanta Hartsfield-Jackson (ATL) and 7h 55m via Chicago O'Hare Intl (ORD).
What is the time difference between Santa Ana and Greenville?
Greenville is 3 hours ahead of Santa Ana (Eastern Time vs Pacific Time). Plan for the time shift when scheduling connections or first-day activities.

If your dates are flexible, aim for a Friday departure and avoid flying on Tuesday. On this route, Friday flights average $452, about $191 less than Tuesday fares (30% savings) based on the last 12 months.
If you can choose when to travel, plan your Santa Ana to Greenville trip for May. Fares historically average $433 round-trip in that month - typically $454 less than the most expensive month, which is February (based on the last 12 months).

More options for your flight from Santa Ana to Greenville

Add a hotel or car rental

Airports

Cabin class

Direct Flights

Origins

Other destinations

Return flight

Complete your trip to Greenville with a hotel stay or car rental

Car rentals in Greenville

Hotels in Greenville

Vacations in Greenville

SNA - GSP

$173 Find Cheap Flights from John Wayne (Santa Ana) to Greenville - Compare and Save

Everything you should know

Cheap Flights from Santa Ana to Greenville (SNA-GSP)

Recent round-trip flight deals from Santa Ana to Greenville

Recent one-way flight deals from Santa Ana to Greenville

Recent last minute flight deals from Santa Ana to Greenville

Price, demand and travel trends for Santa Ana to Greenville flights

How much is a round-trip flight from Santa Ana to Greenville?

What's the cheapest day of the week to fly from Santa Ana to Greenville?

What’s the cheapest month to fly from Santa Ana to Greenville?

Which airline is the cheapest to fly from Santa Ana to Greenville?

What’s the most popular layover airport when flying from Santa Ana to Greenville?

What is the cheapest layover airport when flying from Santa Ana to Greenville?

When flying from Santa Ana to Greenville which airport offers the shortest layover?

Key details for Santa Ana to Greenville flights

Low season

High season

Cheapest flight

When to book flights from Santa Ana to Greenville

Your Santa Ana to Greenville flight questions, answered

Your guide to booking Santa Ana to Greenville flights

More options for your flight from Santa Ana to Greenville

Complete your trip to Greenville with a hotel stay or car rental

Information on your arrival and departure airports

Cabin class types available on flights from John Wayne (Santa Ana) to Greenville

Find direct flights to and from Santa Ana and Greenville

Flights from domestic origins to Greenville

Flights to other popular destinations

Find deals for your return flight