SNA - GSP

$202 Find Cheap Flights from John Wayne (Santa Ana) to Greenville - Compare and Save

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Everything you should know

Cheapest round-trip
$393
Typical prices: $452-$608
Delta
Sat 12/15Fri 1/12
SNA - GSP • 1 stop
Cheapest one-way
$202
Typical prices: $349-$553
American Airlines
Sun 12/2
SNA - GSP • 1 stop
Nonstop flights
Not available
There are currently no direct flights between Santa Ana and Greenville. You'll need to take a connecting flight to reach the destination.
Insights
Insights
When to travel
May
Cheapest • 19% price drop
June
Most popular
Good to know
+1
Good to know
+1
Top layover airports
Atlanta Hartsfield-Jackson (ATL)
Cheapest • Avg $518 (round-trip)
Dallas/Fort Worth (DFW)
Shortest trip • 7h 21m (one-way)
Insights
Insights
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Flight Deals

Cheap Flights from Santa Ana to Greenville (SNA-GSP)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Santa Ana to Greenville

Tue, Dec 15 - Tue, Jan 12
Delta Logo
12:00 pm - 10:22 pmSNA  Santa Ana J. Wayne/Orange Cnty-GSP Greenville
7h 22m1 stop Atlanta Hartsfield-Jackson
Delta Logo
5:38 am - 11:20 amGSP  Greenville-SNA Santa Ana J. Wayne/Orange Cnty
8h 42m1 stop Atlanta Hartsfield-Jackson
$393Delta
Tue, Dec 15 - Thu, Jan 14
Delta Logo
12:00 pm - 10:22 pmSNA  Santa Ana J. Wayne/Orange Cnty-GSP Greenville
7h 22m1 stop Atlanta Hartsfield-Jackson
Delta Logo
5:38 am - 11:20 amGSP  Greenville-SNA Santa Ana J. Wayne/Orange Cnty
8h 42m1 stop Atlanta Hartsfield-Jackson
$408Delta
Thu, Dec 17 - Tue, Jan 12
Delta Logo
2:30 pm - 11:47 pmSNA  Santa Ana J. Wayne/Orange Cnty-GSP Greenville
6h 17m1 stop Atlanta Hartsfield-Jackson
Delta Logo
5:38 am - 11:20 amGSP  Greenville-SNA Santa Ana J. Wayne/Orange Cnty
8h 42m1 stop Atlanta Hartsfield-Jackson
$408Delta
Tue, Dec 15 - Mon, Jan 11
Delta Logo
12:00 pm - 10:22 pmSNA  Santa Ana J. Wayne/Orange Cnty-GSP Greenville
7h 22m1 stop Atlanta Hartsfield-Jackson
Delta Logo
5:38 am - 11:20 amGSP  Greenville-SNA Santa Ana J. Wayne/Orange Cnty
8h 42m1 stop Atlanta Hartsfield-Jackson
$408Delta
Wed, Dec 16 - Sun, Dec 20
American Airlines Logo
10:47 am - 9:52 pmSNA  Santa Ana J. Wayne/Orange Cnty-GSP Greenville
8h 05m1 stop Dallas/Fort Worth
American Airlines Logo
5:22 pm - 10:31 pmGSP  Greenville-SNA Santa Ana J. Wayne/Orange Cnty
8h 09m1 stop Dallas/Fort Worth
$450American Airlines
Thu, Dec 24 - Thu, Dec 31
American Airlines Logo
1:10 pm - 10:33 pmSNA  Santa Ana J. Wayne/Orange Cnty-GSP Greenville
6h 23m1 stop Dallas/Fort Worth
American Airlines Logo
7:40 am - 2:04 pmGSP  Greenville-SNA Santa Ana J. Wayne/Orange Cnty
9h 24m1 stop Dallas/Fort Worth
$464American Airlines
Sun, Jan 17 - Thu, Jan 21
American Airlines Logo
7:45 am - 8:22 pmSNA  Santa Ana J. Wayne/Orange Cnty-GSP Greenville
9h 37m1 stop Charlotte Douglas
American Airlines Logo
2:40 pm - 9:16 pmGSP  Greenville-SNA Santa Ana J. Wayne/Orange Cnty
9h 36m1 stop Dallas/Fort Worth
$465American Airlines
Sun, Jan 17 - Thu, Jan 21
United Airlines Logo
12:04 pm - 9:59 pmSNA  Santa Ana J. Wayne/Orange Cnty-GSP Greenville
6h 55m1 stop Houston George Bush Intcntl
United Airlines Logo
12:35 pm - 10:14 pmGSP  Greenville-SNA Santa Ana J. Wayne/Orange Cnty
12h 39m2 stops Newark Denver Intl
$470United Airlines
Fri, Dec 11 - Sun, Dec 13
United Airlines Logo
7:42 pm - 9:52 amSNA  Santa Ana J. Wayne/Orange Cnty-GSP Greenville
11h 10m2 stops San Francisco Chicago O'Hare Intl
United Airlines Logo
6:30 am - 11:37 amGSP  Greenville-SNA Santa Ana J. Wayne/Orange Cnty
8h 07m1 stop Chicago O'Hare Intl
$480United Airlines
Wed, Dec 16 - Wed, Jan 13
United Airlines Logo
10:20 am - 8:59 pmSNA  Santa Ana J. Wayne/Orange Cnty-GSP Greenville
7h 39m1 stop Chicago O'Hare Intl
United Airlines Logo
2:57 pm - 8:23 pmGSP  Greenville-SNA Santa Ana J. Wayne/Orange Cnty
8h 26m1 stop Washington, D.C. Dulles Intl
$523United Airlines
Booking Insights

Price, demand and travel trends for Santa Ana to Greenville flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

How much is a round-trip flight from Santa Ana to Greenville?

Round-trip flights from Santa Ana to Greenville typically range from $452 to $608. The lowest price found in the past 5 days was $393, on Delta.

What's the cheapest day of the week to fly from Santa Ana to Greenville?

Based on deals KAYAK users found in the last 12 months, Wednesday is the cheapest day of the week to fly from Santa Ana to Greenville. It’s 19% cheaper than the average day, while Monday is the most expensive, with prices 16% higher.

What’s the cheapest month to fly from Santa Ana to Greenville?

•May is the cheapest month to fly from Santa Ana to Greenville at $433 round-trip.
•February ($887) and August ($706) are the most expensive months.
•The price difference between flying in the cheapest and most expensive months is 104% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.

Find deals

Key details for Santa Ana to Greenville flights

Low season

March

Cheapest flight

$202
Beat the crowds with an average 58% drop in travelers.
The most popular month to fly with an average 124% increase in travelers.
One-way flight from Santa Ana to Greenville

When to book flights from Santa Ana to Greenville

Are your dates flexible? Find out the best times to travel from Santa Ana to Greenville based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Santa Ana to Greenville flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines and booking tips.

  • What cabin classes can I book on flights from Santa Ana to Greenville?

    Only Economy Class is available on flights from Santa Ana to Greenville.

  • How long is a flight from Santa Ana to Greenville?

    A nonstop flight from Santa Ana to Greenville takes 00m, covering 2,025 miles.

  • Do I need a passport to fly from Santa Ana to Greenville?

    No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID or another TSA-accepted form of identification.

  • How much should I expect to pay for a Santa Ana to Greenville flight?

    Round-trip flights from Santa Ana to Greenville range from $452 to $608, with an average of $533 over the past 12 months. Anything below $452 counts as a good deal.

  • Have flight prices from Santa Ana to Greenville changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $393 to $2,112. That means the highest observed fare was about 5x higher than the lowest one.

  • How are flight prices from Santa Ana to Greenville looking right now?

    One-way fares from Santa Ana to Greenville are currently higher than usual. Average one-way flight prices are about $716, which is 88% above the typical average for this route.

  • What car rental options are available at Greenville Airport (GSP)?

    Greenville Airport (GSP) hosts 5 major car rental companies, with daily rates averaging $67 for economy cars. Top options include:

    • Budget
    • Alamo
    • Thrifty
    • Enterprise Rent-A-Car
    • Avis

  • Which airports can I use when flying from Santa Ana to Greenville?

    Flights from Santa Ana to Greenville usually depart from Santa Ana J. Wayne/Orange Cnty (SNA) and arrive at Greenville (GSP).

  • Which airports do connecting flights from Santa Ana to Greenville pass through?

    One-stop flights from Santa Ana to Greenville most commonly connect through:

    • Dallas/Fort Worth (DFW) - 74% of one-stop connections
    • Atlanta Hartsfield-Jackson (ATL) - 14% of one-stop connections
    • Chicago O'Hare Intl (ORD) - 12% of one-stop connections

  • Can I save money by using flexible dates for flights from Santa Ana to Greenville?

    Yes. Flexible dates can save you up to 31% on flights from Santa Ana to Greenville. Wednesday is the cheapest departure day at $435 round-trip on average, while Monday is the most expensive at $622, a difference of $187.

    KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • How much time can I save by choosing a different layover airport from Santa Ana to Greenville?

    Flying via Atlanta Hartsfield-Jackson (ATL) gives the shortest average 1-stop total travel time at 7h 18m, compared with 7h 21m via Dallas/Fort Worth (DFW) and 7h 52m via Chicago O'Hare Intl (ORD).

  • What is the time difference between Santa Ana and Greenville?

    Greenville is 3 hours ahead of Santa Ana (Eastern Time vs Pacific Time). Plan for the time shift when scheduling connections or first-day activities.

Your guide to booking Santa Ana to Greenville flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates are flexible, aim for a Wednesday departure and avoid flying on Monday. On this route, Wednesday flights average $435, about $187 less than Monday fares (30% savings) based on the last 12 months.
  • If you can choose when to travel, plan your Santa Ana to Greenville trip for May. Fares historically average $433 round-trip in that month - typically $454 less than the most expensive month, which is February (based on the last 12 months).

More options for your flight from Santa Ana to Greenville

Complete your trip to Greenville with a hotel stay or car rental

Car rentals in Greenville
Hotels in Greenville
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