Which airports can I use when flying from Santa Ana to Greenville?

Flights from Santa Ana to Greenville usually depart from Santa Ana J. Wayne/Orange Cnty (SNA) and arrive at Greenville (GSP).

What cabin classes can I book on flights from Santa Ana to Greenville?

Only Economy Class is available on flights from Santa Ana to Greenville.

Which airports do connecting flights from Santa Ana to Greenville pass through?

One-stop flights from Santa Ana to Greenville most commonly connect through: • Dallas/Fort Worth (DFW) - 73% of one-stop connections • Atlanta Hartsfield-Jackson (ATL) - 15% of one-stop connections • Chicago O'Hare Intl (ORD) - 13% of one-stop connections

Can I save money by using flexible dates for flights from Santa Ana to Greenville?

Yes. Flexible dates can save you up to 28% on flights from Santa Ana to Greenville. Friday is the cheapest departure day at $452 round-trip on average, while Monday is the most expensive at $622, a difference of $170. KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

How long is a flight from Santa Ana to Greenville?

A nonstop flight from Santa Ana to Greenville takes 00m, covering 2,025 miles.

Do I need a passport to fly from Santa Ana to Greenville?

No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID or another TSA-accepted form of identification.

Have flight prices from Santa Ana to Greenville changed much recently?

Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $319 to $1,715. That means the highest observed fare was about 5x higher than the lowest one.

How are flight prices from Santa Ana to Greenville looking right now?

One-way fares from Santa Ana to Greenville are currently lower than usual. Average one-way flight prices are about $211, which is 43% below the typical average for this route.

How much time can I save by choosing a different layover airport from Santa Ana to Greenville?

Flying via Atlanta Hartsfield-Jackson (ATL) gives the shortest average 1-stop total travel time at 7h 18m, compared with 7h 19m via Dallas/Fort Worth (DFW) and 7h 52m via Chicago O'Hare Intl (ORD).

What is the time difference between Santa Ana and Greenville?

Greenville is 3 hours ahead of Santa Ana (Eastern Time vs Pacific Time). Plan for the time shift when scheduling connections or first-day activities.

What car rental options are available at Greenville Airport (GSP)?

Greenville Airport (GSP) hosts 5 major car rental companies, with daily rates averaging $66 for economy cars. Top options include: • Budget • Alamo • Thrifty • Enterprise Rent-A-Car • Avis

How much should I expect to pay for a Santa Ana to Greenville flight?

Round-trip flights from Santa Ana to Greenville range from $469 to $643, with an average of $586 over the past 12 months. Anything below $469 counts as a good deal.

How much is a round-trip flight from Santa Ana to Greenville?

Round-trip flights from Santa Ana to Greenville typically range from $469 to $643. The lowest price found in the past 5 days was $319, on Delta.

What's the cheapest day of the week to fly from Santa Ana to Greenville?

Based on deals KAYAK users found in the last 12 months, Friday is the cheapest day of the week to fly from Santa Ana to Greenville. It’s 23% cheaper than the average day, while Monday is the most expensive, with prices 6% higher.

What’s the cheapest month to fly from Santa Ana to Greenville?

•May is the cheapest month to fly from Santa Ana to Greenville at $433 round-trip. •February ($887) and December ($746) are the most expensive months. •The price difference between flying in the cheapest and most expensive months is 104% on average. This is based on KAYAK aggregated and averaged internal data over the past 12 months.

Which airline is the cheapest to fly from Santa Ana to Greenville?

Delta ($319) and United Airlines ($324) are the cheapest airlines to fly round-trip from Santa Ana to Greenville according to KAYAK data over the last 5 days.

What’s the most popular layover airport when flying from Santa Ana to Greenville?

Dallas/Fort Worth (DFW) is the most popular layover for the Santa Ana to Greenville route. 73% of KAYAK users who booked 1-stop round-trips over the past 3 months connected via DFW.

What is the cheapest layover airport when flying from Santa Ana to Greenville?

Flights via Atlanta Hartsfield-Jackson (ATL) offer the most affordable fares, with an average round-trip price of $518. Based on KAYAK data over the past 3 months.

When flying from Santa Ana to Greenville which airport offers the shortest layover?

Dallas/Fort Worth (DFW) had the shortest average connection time for Santa Ana to Greenville layovers at 4h 18m over the past 3 months.

$160 CHEAP FLIGHTS from John Wayne (Santa Ana) to Greenville (SNA - GSP)

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Filter searches by price, airline and more to find your best flights.

Cheapest round-trip

$319

Typical prices: $469-$643

Delta

Wed 12/5Sat 12/8

SNA - GSP • 1 stop

Cheapest one-way

$160

Typical prices: $260-$549

American Airlines

Sun 12/9

SNA - GSP • 1 stop

Nonstop flights

Not available

There are currently no direct flights between Santa Ana and Greenville. You'll need to take a connecting flight to reach the destination.

Insights

When to travel

May

Cheapest • 26% price drop

June

Most popular

Good to know

Top layover airports

Atlanta Hartsfield-Jackson (ATL)

Cheapest • Avg $518 (round-trip)

Dallas/Fort Worth (DFW)

Shortest trip • 7h 19m (one-way)

Insights

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We hope you love your trip to Greenville!

Flight Deals

Cheap Flights from Santa Ana to Greenville (SNA-GSP)

Discover the best prices for you by selecting your travel dates on KAYAK.

Round-trip

One-way

Last minute

Recent round-trip flight deals from Santa Ana to Greenville

Sat, Dec 5 - Tue, Dec 8

1:00 pm - 10:22 pmSNA Santa Ana J. Wayne/Orange Cnty-GSP Greenville

6h 22m1 stop Atlanta Hartsfield-Jackson

5:40 am - 11:48 amGSP Greenville-SNA Santa Ana J. Wayne/Orange Cnty

9h 08m1 stop Atlanta Hartsfield-Jackson

$319Delta

Thu, Dec 10 - Mon, Dec 14

2:30 pm - 11:47 pmSNA Santa Ana J. Wayne/Orange Cnty-GSP Greenville

6h 17m1 stop Atlanta Hartsfield-Jackson

3:44 pm - 10:18 pmGSP Greenville-SNA Santa Ana J. Wayne/Orange Cnty

9h 34m1 stop Atlanta Hartsfield-Jackson

$319Delta

Thu, Dec 10 - Mon, Dec 14

7:42 pm - 9:52 amSNA Santa Ana J. Wayne/Orange Cnty-GSP Greenville

11h 10m2 stops San Francisco Chicago O'Hare Intl

5:34 pm - 10:30 pmGSP Greenville-SNA Santa Ana J. Wayne/Orange Cnty

7h 56m1 stop Chicago O'Hare Intl

$324United Airlines

Sat, Dec 5 - Tue, Dec 8

7:40 pm - 10:10 amSNA Santa Ana J. Wayne/Orange Cnty-GSP Greenville

11h 30m2 stops Phoenix Sky Harbor Intl Baltimore/Washington

2:50 pm - 9:45 pmGSP Greenville-SNA Santa Ana J. Wayne/Orange Cnty

9h 55m2 stops Baltimore/Washington Denver Intl

$349Southwest

Thu, Dec 10 - Mon, Dec 14

6:45 am - 4:53 pmSNA Santa Ana J. Wayne/Orange Cnty-GSP Greenville

7h 08m1 stop Chicago O'Hare Intl

5:00 pm - 9:45 pmGSP Greenville-SNA Santa Ana J. Wayne/Orange Cnty

7h 45m1 stop Houston George Bush Intcntl

$356United Airlines

Mon, Jan 11 - Thu, Jan 14

2:40 pm - 11:53 pmSNA Santa Ana J. Wayne/Orange Cnty-GSP Greenville

6h 13m1 stop Atlanta Hartsfield-Jackson

7:00 am - 11:20 amGSP Greenville-SNA Santa Ana J. Wayne/Orange Cnty

7h 20m1 stop Atlanta Hartsfield-Jackson

$369Delta

Wed, Dec 30 - Wed, Jan 6

6:30 pm - 9:28 amSNA Santa Ana J. Wayne/Orange Cnty-GSP Greenville

11h 58m2 stops San Francisco Chicago O'Hare Intl

5:15 pm - 9:53 pmGSP Greenville-SNA Santa Ana J. Wayne/Orange Cnty

7h 38m1 stop Houston George Bush Intcntl

$390United Airlines

Sat, Dec 5 - Tue, Dec 8

10:47 am - 11:01 pmSNA Santa Ana J. Wayne/Orange Cnty-GSP Greenville

9h 14m2 stops Dallas/Fort Worth Charlotte Douglas

3:26 pm - 10:17 pmGSP Greenville-SNA Santa Ana J. Wayne/Orange Cnty

9h 51m1 stop Charlotte Douglas

$406American Airlines

Thu, Dec 10 - Sun, Dec 13

12:10 pm - 9:52 pmSNA Santa Ana J. Wayne/Orange Cnty-GSP Greenville

6h 42m1 stop Dallas/Fort Worth

7:45 am - 3:42 pmGSP Greenville-SNA Santa Ana J. Wayne/Orange Cnty

10h 57m2 stops Dallas/Fort Worth Phoenix Sky Harbor Intl

$446American Airlines

Wed, Dec 30 - Wed, Jan 6

7:56 am - 8:02 pmSNA Santa Ana J. Wayne/Orange Cnty-GSP Greenville

9h 06m1 stop Chicago O'Hare Intl

7:10 am - 12:22 pmGSP Greenville-SNA Santa Ana J. Wayne/Orange Cnty

8h 12m1 stop Dallas/Fort Worth

$477American Airlines

Recent last minute flight deals from Santa Ana to Greenville

Wed, Nov 4 - Tue, Nov 10

7:15 am - 4:50 pmSNA Santa Ana J. Wayne/Orange Cnty-GSP Greenville

6h 35m1 stop Charlotte Douglas

4:37 pm - 9:24 pmGSP Greenville-SNA Santa Ana J. Wayne/Orange Cnty

7h 47m1 stop Chicago O'Hare Intl

$886American Airlines

Wed, Nov 4 - Tue, Nov 10

8:49 am - 9:59 pmSNA Santa Ana J. Wayne/Orange Cnty-GSP Greenville

10h 10m1 stop Chicago O'Hare Intl

7:51 am - 3:42 pmGSP Greenville-SNA Santa Ana J. Wayne/Orange Cnty

10h 51m2 stops Dallas/Fort Worth Phoenix Sky Harbor Intl

$891American Airlines

Wed, Nov 4 - Tue, Nov 10

8:00 am - 8:31 pmSNA Santa Ana J. Wayne/Orange Cnty-GSP Greenville

9h 31m2 stops Dallas/Fort Worth Charlotte Douglas

7:51 am - 3:42 pmGSP Greenville-SNA Santa Ana J. Wayne/Orange Cnty

10h 51m2 stops Dallas/Fort Worth Phoenix Sky Harbor Intl

$897American Airlines

Thu, Nov 5 - Mon, Nov 9

8:15 am - 7:01 pmSNA Santa Ana J. Wayne/Orange Cnty-GSP Greenville

7h 46m1 stop Washington, D.C. Dulles Intl

2:51 pm - 8:28 pmGSP Greenville-SNA Santa Ana J. Wayne/Orange Cnty

8h 37m1 stop Washington, D.C. Dulles Intl

$1,017United Airlines

Wed, Nov 4 - Tue, Nov 10

4:37 pm - 1:33 pmSNA Santa Ana J. Wayne/Orange Cnty-GSP Greenville

17h 56m1 stop Dallas/Fort Worth

5:17 pm - 8:22 amGSP Greenville-SNA Santa Ana J. Wayne/Orange Cnty

18h 05m1 stop Dallas/Fort Worth

$1,049American Airlines

Wed, Nov 4 - Tue, Nov 10

6:45 am - 9:58 pmSNA Santa Ana J. Wayne/Orange Cnty-GSP Greenville

12h 13m2 stops Phoenix Sky Harbor Intl Dallas/Fort Worth

5:17 pm - 8:22 amGSP Greenville-SNA Santa Ana J. Wayne/Orange Cnty

18h 05m1 stop Dallas/Fort Worth

$1,096American Airlines

Wed, Nov 4 - Tue, Nov 10

8:00 am - 8:31 pmSNA Santa Ana J. Wayne/Orange Cnty-GSP Greenville

9h 31m2 stops Dallas/Fort Worth Charlotte Douglas

11:54 am - 6:54 pmGSP Greenville-SNA Santa Ana J. Wayne/Orange Cnty

10h 00m2 stops Charlotte Douglas Phoenix Sky Harbor Intl

$1,107American Airlines

Thu, Nov 5 - Mon, Nov 9

6:48 am - 9:59 pmSNA Santa Ana J. Wayne/Orange Cnty-GSP Greenville

12h 11m2 stops Seattle/Tacoma Intl Chicago O'Hare Intl

11:40 am - 10:25 pmGSP Greenville-SNA Santa Ana J. Wayne/Orange Cnty

13h 45m2 stops Chicago O'Hare Intl Seattle/Tacoma Intl

$3,575Alaska Airlines

Booking Insights

Price, demand and travel trends for Santa Ana to Greenville flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

Prices

Airlines

Layovers

How much is a round-trip flight from Santa Ana to Greenville? This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Santa Ana to Greenville departing in december.
What's the cheapest day of the week to fly from Santa Ana to Greenville?: Based on deals KAYAK users found in the last 12 months, Friday is the cheapest day of the week to fly from Santa Ana to Greenville. It’s 23% cheaper than the average day, while Monday is the most expensive, with prices 6% higher.
What’s the cheapest month to fly from Santa Ana to Greenville? KAYAK internal proprietary data takes all prices for each month over the last 12 months for round-trip flights from Santa Ana to Greenville, removes the top 0.1% to account for outliers and then takes the median of all values for each month.: •May is the cheapest month to fly from Santa Ana to Greenville at $433 round-trip.
•February ($887) and December ($746) are the most expensive months.
•The price difference between flying in the cheapest and most expensive months is 104% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.

Find deals

Low season	March
High season	June
Cheapest flight	$160

Beat the crowds with an average 59% drop in travelers.

The most popular month to fly with an average 118% increase in travelers.

One-way flight from Santa Ana to Greenville

When to book flights from Santa Ana to Greenville

Are your dates flexible? Find out the best times to travel from Santa Ana to Greenville based on our flight data from the last year. Discover the cheapest month and even day to fly.

Estimated round-trip price

KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

What cabin classes can I book on flights from Santa Ana to Greenville?
Only Economy Class is available on flights from Santa Ana to Greenville.
How long is a flight from Santa Ana to Greenville?
A nonstop flight from Santa Ana to Greenville takes 00m, covering 2,025 miles.
Do I need a passport to fly from Santa Ana to Greenville?
No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID or another TSA-accepted form of identification.
How much should I expect to pay for a Santa Ana to Greenville flight?
Round-trip flights from Santa Ana to Greenville range from $469 to $643, with an average of $586 over the past 12 months. Anything below $469 counts as a good deal.
Have flight prices from Santa Ana to Greenville changed much recently?
Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $319 to $1,715. That means the highest observed fare was about 5x higher than the lowest one.
How are flight prices from Santa Ana to Greenville looking right now?
One-way fares from Santa Ana to Greenville are currently lower than usual. Average one-way flight prices are about $211, which is 43% below the typical average for this route.
What car rental options are available at Greenville Airport (GSP)?
Greenville Airport (GSP) hosts 5 major car rental companies, with daily rates averaging $66 for economy cars. Top options include:

• Budget
• Alamo
• Thrifty
• Enterprise Rent-A-Car
• Avis
Which airports can I use when flying from Santa Ana to Greenville?
Flights from Santa Ana to Greenville usually depart from Santa Ana J. Wayne/Orange Cnty (SNA) and arrive at Greenville (GSP).
Which airports do connecting flights from Santa Ana to Greenville pass through?
One-stop flights from Santa Ana to Greenville most commonly connect through:

• Dallas/Fort Worth (DFW) - 73% of one-stop connections
• Atlanta Hartsfield-Jackson (ATL) - 15% of one-stop connections
• Chicago O'Hare Intl (ORD) - 13% of one-stop connections
Can I save money by using flexible dates for flights from Santa Ana to Greenville?
Yes. Flexible dates can save you up to 28% on flights from Santa Ana to Greenville. Friday is the cheapest departure day at $452 round-trip on average, while Monday is the most expensive at $622, a difference of $170.

KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.
How much time can I save by choosing a different layover airport from Santa Ana to Greenville?
Flying via Atlanta Hartsfield-Jackson (ATL) gives the shortest average 1-stop total travel time at 7h 18m, compared with 7h 19m via Dallas/Fort Worth (DFW) and 7h 52m via Chicago O'Hare Intl (ORD).
What is the time difference between Santa Ana and Greenville?
Greenville is 3 hours ahead of Santa Ana (Eastern Time vs Pacific Time). Plan for the time shift when scheduling connections or first-day activities.

If your dates are flexible, aim for a Friday departure and avoid flying on Monday. On this route, Friday flights average $452, about $170 less than Monday fares (27% savings) based on the last 12 months.
If you can choose when to travel, plan your Santa Ana to Greenville trip for May. Fares historically average $433 round-trip in that month - typically $454 less than the most expensive month, which is February (based on the last 12 months).

More options for your flight from Santa Ana to Greenville

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Vacations in Greenville

SNA - GSP

$160 Find Cheap Flights from John Wayne (Santa Ana) to Greenville - Compare and Save

Everything you should know

Cheap Flights from Santa Ana to Greenville (SNA-GSP)

Recent round-trip flight deals from Santa Ana to Greenville

Recent one-way flight deals from Santa Ana to Greenville

Recent last minute flight deals from Santa Ana to Greenville

Price, demand and travel trends for Santa Ana to Greenville flights

How much is a round-trip flight from Santa Ana to Greenville?

What's the cheapest day of the week to fly from Santa Ana to Greenville?

What’s the cheapest month to fly from Santa Ana to Greenville?

Which airline is the cheapest to fly from Santa Ana to Greenville?

What’s the most popular layover airport when flying from Santa Ana to Greenville?

What is the cheapest layover airport when flying from Santa Ana to Greenville?

When flying from Santa Ana to Greenville which airport offers the shortest layover?

Key details for Santa Ana to Greenville flights

Low season

High season

Cheapest flight

When to book flights from Santa Ana to Greenville

Your Santa Ana to Greenville flight questions, answered

Your guide to booking Santa Ana to Greenville flights

More options for your flight from Santa Ana to Greenville

Complete your trip to Greenville with a hotel stay or car rental

Information on your arrival and departure airports

Cabin class types available on flights from John Wayne (Santa Ana) to Greenville

Find direct flights to and from Santa Ana and Greenville

Flights from domestic origins to Greenville

Flights to other popular destinations

Find deals for your return flight