$111 Find Cheap Flights from John Wayne (Santa Ana) to Indiana - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Santa Ana to Indiana departing on 9/10. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
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Cheap Flights from Santa Ana to Indiana

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Indianapolis
Indianapolis1 stop$278
South Bend
South Bend1 stop$321
Fort Wayne
Fort Wayne1 stop$333
Evansville
Evansville1 stop$453
Chicago
Chicago2 stops$327
Dayton
Dayton1 stop$359
Indianapolis
Indianapolis1 stop$278
South Bend
South Bend1 stop$321
Fort Wayne
Fort Wayne1 stop$333
Evansville
Evansville1 stop$453
Chicago
Chicago2 stops$327
Dayton
Dayton1 stop$359

Book Cheap Santa Ana to Indiana Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Santa Ana to Indiana that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Santa Ana to Indiana

Mon, Sep 14 - Mon, Sep 21
Frontier Logo
4:35 pm - 6:47 am
SNA
-
CVG
11h 12m
1 stop
Frontier Logo
8:45 am - 5:15 pm
CVG
-
SNA
11h 30m
1 stop
$224Frontier
Thu, Sep 24 - Mon, Sep 28
Frontier Logo
4:35 pm - 6:47 am
SNA
-
CVG
11h 12m
1 stop
Frontier Logo
8:45 am - 5:15 pm
CVG
-
SNA
11h 30m
1 stop
$254Frontier
Mon, Aug 24 - Tue, Sep 1
Multiple Airlines Logo
7:53 pm - 8:15 pm
SNA
-
CVG
21h 22m
1 stop
Multiple Airlines Logo
9:20 pm - 5:45 pm
CVG
-
SNA
23h 25m
1 stop
$273Multiple Airlines
Thu, Aug 27 - Tue, Sep 1
Multiple Airlines Logo
7:53 pm - 8:15 pm
SNA
-
CVG
21h 22m
1 stop
Multiple Airlines Logo
9:20 pm - 5:45 pm
CVG
-
SNA
23h 25m
1 stop
$273Multiple Airlines
Sat, Aug 29 - Sat, Sep 5
American Airlines Logo
8:00 am - 6:08 pm
SNA
-
SBN
7h 08m
1 stop
American Airlines Logo
12:34 pm - 5:29 pm
SBN
-
SNA
7h 55m
1 stop
$321American Airlines
Sat, Sep 12 - Sat, Sep 19
United Airlines Logo
2:17 pm - 11:33 pm
SNA
-
SBN
6h 16m
1 stop
United Airlines Logo
1:45 pm - 8:24 pm
SBN
-
SNA
9h 39m
1 stop
$321United Airlines
Wed, Sep 9 - Sat, Sep 19
Delta Logo
11:38 am - 9:40 pm
SNA
-
SBN
7h 02m
1 stop
Delta Logo
6:15 am - 12:33 pm
SBN
-
SNA
9h 18m
1 stop
$321Delta
Fri, Sep 11 - Wed, Sep 16
Delta Logo
11:38 am - 9:40 pm
SNA
-
SBN
7h 02m
1 stop
Delta Logo
5:03 pm - 10:04 pm
SBN
-
SNA
8h 01m
1 stop
$321Delta
Sat, Oct 17 - Sat, Oct 24
American Airlines Logo
6:45 am - 3:47 pm
SNA
-
CVG
6h 02m
1 stop
American Airlines Logo
10:33 am - 2:33 pm
CVG
-
SNA
7h 00m
1 stop
$323American Airlines
Sat, Sep 12 - Sat, Sep 19
United Airlines Logo
10:33 am - 9:48 pm
SNA
-
SBN
8h 15m
1 stop
United Airlines Logo
9:15 am - 3:12 pm
SBN
-
SNA
8h 57m
2 stops
$326United Airlines
Booking Insights

KAYAK's insights & trends for Santa Ana to Indiana flights

Get data-powered insights and trends into flights from Santa Ana to Indiana to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Santa Ana, California to Indiana?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Santa Ana, California to Indiana departing in September.

Flight prices are below average for this route right now.

Flights to Indiana from Santa Ana, California usually cost between $374 and $536 in September.
The lowest price found in the past 5 days was $278 on Multiple Airlines (Sep 9-Sep 16).

What is the cheapest month to fly from John Wayne (Santa Ana) to Indiana?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Santa Ana to Indiana, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from John Wayne (Santa Ana) to Indiana is September, when tickets cost $416 (return) on average. On the other hand, the most expensive months are June and January, when the average cost of round-trip tickets is $557 and $556 respectively.

How far in advance should I book a flight from John Wayne (Santa Ana) to Indiana?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Santa Ana to Indiana, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from John Wayne (Santa Ana) to Indiana, you should book around 4 weeks before departure, which saves you about 57% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 11 weeks before departure.

Good to know

Low season

January

Cheapest flight

$111
Best time to beat the crowds with an average 8% drop in price.
Most popular time to fly with an average 15% increase in price.
Flight from John Wayne (Santa Ana) to Fort Wayne

FAQs - booking Indiana flights

  • How does KAYAK find such low prices on flights from John Wayne (Santa Ana) to Indiana?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from John Wayne (Santa Ana) to Indiana.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from John Wayne (Santa Ana) to Indiana?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from John Wayne (Santa Ana) to Indiana is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from John Wayne (Santa Ana) to Indiana?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from John Wayne (Santa Ana) to Indiana with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from John Wayne (Santa Ana) to Indiana?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from John Wayne (Santa Ana) to Indiana up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Top tips for finding cheap flights to Indiana

  • Looking for a cheap flight? 25% of our users found tickets from John Wayne (Santa Ana) to the following destinations at these prices or less: Chicago $263 one-way - $393 round-trip

Reviews of the top 4 airlines serving from Santa Ana to Indiana

 
See real verified KAYAK customer reviews for airlines flying from John Wayne (Santa Ana) to Indiana. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Santa Ana to Indiana? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
SouthwestOverall score based on 4226 reviews
7.5Entertainment
7.0Food
8.1Boarding
8.0Comfort
8.6Crew
Airline reviews

Red eye from San Diego. Temperature of the cabin was way too warm and the air duct flowed very little air.

6.0 GoodGordon, Jul 2026
SAN - MCO
Read more Southwest reviews

Red eye from San Diego. Temperature of the cabin was way too warm and the air duct flowed very little air.

I think Southwest is the number one airline that anyone can fly I have flown for the first time Frontier and what a joke and their customer service United was a very strange experience I'm only sticking to Southwest from here on out for sure

Great job Southwest! My family doesn't fly often but we felt safe the whole time.

Flight was delayed, full flight and I had to change gates. Southwest flights are always late later in the day.

Was fine, delayed and feels like southwest is always late

The entire experience from boarding to landing was amazing! The crew were very friendly. Will definitely be back.

I realize they are still working out kinks with the new boarding process, but by the time I boarded in group 5, most of the bins were full. All airlines should better enforce small bags and jackets going under the seats until everyone has boarded.

Great flight, 47 passengers on a 180 seat plane. Stewardess was pleasant and cheerful.

This was a nicer flight - not fully booked and so we were able to spread out.

The 700 model seating is too tight both seat size & leg room

Delta is always late. Ruined our first day of a short vacation. Timing is important. We pay to stay on an itinerary

Seats were not bad enough and uncomfortable good legroom in the emergency exit row we were in, but we were forbidden to hold my grandson on my lap for a little while, and the stewardess passed us saying it was against regulations which makes little or no sense when you’re 36,000 feet. The food snacks were really bad. Tasteless tasted like wallpaper, but we’re supposed to be protein bars, and the announcements were all completely incoherent because of the noise of the airplane and the lowness and crackly nature of the PA system.. this was disgraceful. No one in our party could understand a word of what the captain or the flight attendant were saying —not a word! The landing was a little hairy in a pretty stiff crosswind -we bounced before the plane stabilized on the runway

Flight team was great and we even arrived ahead of plan!

First The flight got delayed because one of the crew members was late and we couldn’t board until she arrived. Then we all boarded and got held in the tarmac for another 30 min.

Crew was absolutely fantastic and we’re so welcoming and friendly ❤️

Two delays on two separate planes with parts they could not easily find and replace.

No entertainment. Plane was so small had to pink tag a carry on ive used for 20 years easily on board. The fact the flight got in at midnight, had to wait for crew in fort wayne to allow the plane to approach the gate, THEN had to wait for bag on jet bridge made experience irritating at best.

Flight late, the waited for a long time for “personal” to arrive at gate to dock the plane in Rochester. So annoying. This flight was expected, why aren’t personel available for the jet bridge?

Flight delayed for two and half hours and then canceled altogether due to mechanical issues. No mechanic onsite to fix so had to send one from LAX.

Flight and seats were great. Food service was average at best. The real main problem we had is that we got cheeseburgers for the kids but the plates was extremely hot. Like ridiculously hot and the stewardess never said anything. Luckily or unluckily my wife touched the plate and was able to deal with it before the kids got burned.

Flight was late, the only reason I almost missed my flight was that my connection was also late.

Onboard staff was courteous, helpful, responsive and friendly. The boarding process was disorganized, poorly communicated, and disheveled. Gate agents were yelling instead of using the PA system, didn’t communicate the timing delay of our flight, and created an atmosphere of chaos rather than order and communication. As far as I know, there was no reason for their. I would hate to see how it operated under extreme conditions. I’ve never seen United Airlines operations in such a state.

Baggage claim signs were not updated with my flight information, so I had to guess. The app wasn't updated either.

It was extremely hot in the cabin the entire flight, vent air was worn

Booked through Kayak Business, had a seat in middle and towards back due to booking rate, not comfortable.

Not a great experience. We paid for the upgrade for premium economy seats and seated ourselves in very comfortable seats. Someone came along with the same seat on their boarding pass. The aircraft had been changed and as a result we were booted out and sent further back to small uncomfortable seats. After complaining we were moved to emergency row seats, which gave us more leg room but the seats don’t recline. For people in our 70’s we found having to sit upright from California to NJ very uncomfortable. Not sure why they chose to move senior citizens instead of the two people that were allowed to take the more comfortable seats. Not happy.

Very poor the plane itself was really old, slight smell that couldn’t be named. I didn’t even get a boarding pass UNTIL AFTER clearing security! Even then, they said when I get to my connected flight I’ll get my 2nd boarding pass there! A bit ridiculous!

Due to one crew member not showing up to work, our flight was significantly delayed causing us to miss our connecting flight in Houston to Mississippi causing us to be delayed by more than 6 hours and missing our event all together. Very disappointing. All because ONE crew member called in sick. United did grant us a $15 meal voucher, which was a small but appreciated concession that I wasn’t able to use because I ordered my lunch and paid for it before applying the concession, and the staff said it was too late to use it. Ugh! We also had a TWO delay coming back from Mississippi, but that was on American Airlines and it was due to weather, so not their fault. Anyway, not at all impressed with United’s handling of our flight and the HUGE disappointment of missing our important family event for our 90 year old mother. All that money and all that stress and emotions for nothing. Having to wait the hour to bring an employee from LAX seemed like something that should not have happened. Why don’t you have a local back-up? Santa Ana is not a little airport in a rural area.

the head jack on my seat didn't work and the power outlet didn't work for my seat

Flight was on time. Staff were friendly. I paid for Economy Plus but was required to check my standard carry-on luggage due to lack of space on the aircraft. This cost me 30 minutes, unexpectedly, in waiting at the baggage claim. This experience did not meet my expectations.

The WiFi didn’t work entire flight, couldn’t watch a movie. The recline button didn’t work

How is it that every American flight from DFW to IND is significantly delayed? This is the third time in two months I have been delayed flying out of DFW - ALWAYS for a maintenance issue. Makes me want to drop flying American altogether…or maybe flying through Dallas. Miserable experience.

Pilots were fantastic - super smooth. First Class flight attendant was very attentive. Main Cabin flight attendant should try to smooth the rough edges of her voice - very shrill / punitive. Hurt my ears just to listen to her. Recognize they have a (tough) job to do - but tone over speakers needs to be less like scolding a 5 year old.

Delayed and horrible communication and sat on flight for an hour before taking off

Our flight was 1.5 hours delayed. There was no weather for the inbound flight, so I don't understand why. This meant a VERY late arrival and only a quick nap before my morning flight.

The flight encountered a delay exceeding 4 hours. The food voucher issued was valued at $12, insufficient to cover our meal expenses. Consequently, I was unable to take my medication, leading to a drop in blood sugar levels and exacerbating my anxiety.

Flights were on time. That's the main consideration since I had to change planes. The entertainment was whatever you bring with you and the food (in Economy) is non-existant. Neither of those was a surprise.

The gate crew did try to help, however they lacked the information as to whether the flight will operate or not. Being delayed 6 hours and in a limbo on whether the flight will operate or not is not fun. The airline having staffing issues is not encouraging at all.

Flight was delayed and missed connecting flight. Did not give warning about delay until we showed up at the airport. Not good.

I love to be able to connect my own devices to the entertainment system. It works great!

Everything you need to know for your flight from Santa Ana to Indiana

Information on your arrival and departure airports