SNA - SDF

$174 Find Cheap Flights from John Wayne (Santa Ana) to Louisville - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Santa Ana to Louisville departing on 8/18. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Louisville

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from John Wayne (Santa Ana) to Louisville, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from John Wayne (Santa Ana) to Louisville, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$355
Typical prices: $336-$453
American Airlines
Sat 9/19Tue 9/22
SNA - SDF • 1 stop
Cheapest one-way
$174
Southwest
Tue 8/18
SNA - SDF • 1 stop
Top airlines
Cheapest • from $355 (round-trip)
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Santa Ana and Louisville. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Cheapest • Avg $388 (round-trip)
Shortest trip • 6h 05m (one-way)
Insights
Insights
Insights
Insights
When to travel
Cheapest • 28% price drop
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Louisville!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Santa Ana to Louisville (SNA-SDF)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Santa Ana to Louisville that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Santa Ana to Louisville

Sat, Sep 19 - Tue, Sep 22
American Airlines Logo
9:12 am - 9:31 pm
SNA
-
SDF
9h 19m
1 stop
American Airlines Logo
6:00 am - 9:45 am
SDF
-
SNA
6h 45m
1 stop
$355American Airlines
Sat, Aug 29 - Sat, Sep 26
Southwest Logo
3:45 pm - 10:25 am
SNA
-
SDF
15h 40m
2 stops
Southwest Logo
4:50 pm - 7:50 pm
SDF
-
SNA
6h 00m
1 stop
$379Southwest
Mon, Oct 12 - Sat, Oct 17
Delta Logo
2:00 pm - 12:02 am
SNA
-
SDF
7h 02m
1 stop
Delta Logo
8:20 am - 12:56 pm
SDF
-
SNA
7h 36m
1 stop
$406Delta
Sat, Aug 29 - Sat, Sep 26
Southwest Logo
3:45 pm - 10:25 am
SNA
-
SDF
15h 40m
2 stops
Southwest Logo
12:05 pm - 6:35 pm
SDF
-
SNA
9h 30m
2 stops
$407Southwest
Tue, Jul 21 - Tue, Jul 28
Southwest Logo
11:05 am - 9:45 pm
SNA
-
SDF
7h 40m
2 stops
Southwest Logo
10:55 am - 4:45 pm
SDF
-
SNA
8h 50m
1 stop
$410Southwest
Tue, Jul 21 - Tue, Jul 28
Southwest Logo
11:10 am - 9:45 pm
SNA
-
SDF
7h 35m
2 stops
Southwest Logo
5:25 pm - 9:55 pm
SDF
-
SNA
7h 30m
2 stops
$416Southwest
Thu, Oct 1 - Sun, Oct 4
Southwest Logo
1:30 pm - 11:15 pm
SNA
-
SDF
6h 45m
1 stop
Southwest Logo
4:55 pm - 10:05 pm
SDF
-
SNA
8h 10m
1 stop
$419Southwest
Mon, Oct 12 - Sat, Oct 17
Delta Logo
2:00 pm - 12:02 am
SNA
-
SDF
7h 02m
1 stop
Delta Logo
8:20 am - 12:56 pm
SDF
-
SNA
7h 36m
1 stop
$432Delta
Thu, Oct 1 - Sun, Oct 4
Southwest Logo
8:15 am - 8:55 pm
SNA
-
SDF
9h 40m
2 stops
Southwest Logo
4:55 pm - 9:05 pm
SDF
-
SNA
7h 10m
1 stop
$433Southwest
Wed, Aug 5 - Sun, Aug 9
Southwest Logo
11:20 am - 10:30 pm
SNA
-
SDF
8h 10m
2 stops
Southwest Logo
6:10 am - 10:00 am
SDF
-
SNA
6h 50m
1 stop
$434Southwest
Booking Insights

KAYAK's insights & trends for Santa Ana to Louisville flights

Get data-powered insights and trends into flights from Santa Ana to Louisville to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from John Wayne (Santa Ana) to Louisville?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Santa Ana to Louisville, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from John Wayne (Santa Ana) to Louisville is January, where tickets cost $402 (return) on average. On the other hand, the most expensive months are November and April, where the average cost of round-trip tickets is $847 and $736 respectively.

Good to know

Low seasonNovember
Cheapest flight$174
Best time to beat the crowds but there is an average 52% increase in price.
Most popular time to fly and prices are also 28% lower on average.
Flight from John Wayne (Santa Ana) to Louisville

When to book flights from Santa Ana to Louisville

Are your dates flexible? Find out the best times to travel from Santa Ana to Louisville based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from John Wayne (Santa Ana) to Louisville

  • What is the cheapest flight from John Wayne (Santa Ana) to Louisville?

    In the last 5 days, the lowest price for a flight from John Wayne (Santa Ana) to Louisville was $174 for a one-way ticket and $355 for a round-trip.

  • Do I need a passport to fly between John Wayne (Santa Ana) and Louisville?

    No

  • Which airports will I be using when flying from John Wayne (Santa Ana) to Louisville?

    John Wayne (Santa Ana) and Louisville are both served by 1 main airport. You will leave John Wayne (Santa Ana) from Santa Ana J. Wayne/Orange Cnty and will be arriving at Louisville Intl.

  • Which airlines offer Wi-Fi service onboard planes from John Wayne (Santa Ana) to Louisville?

    Only American Airlines offers inflight Wi-Fi service on the John Wayne (Santa Ana) to Louisville flight route.

  • Which aircraft models fly most regularly from John Wayne (Santa Ana) to Louisville?

    The Airbus A321 (sharklets) is the aircraft model that flies most regularly on the John Wayne (Santa Ana) to Louisville flight route.

  • Which airline alliances offer flights from John Wayne (Santa Ana) to Louisville?

    oneworld is the only airline alliance operating flights between John Wayne (Santa Ana) and Louisville.

  • Which is the best airline for flights from John Wayne (Santa Ana) to Louisville, Southwest or American Airlines?

    The two airlines most popular with KAYAK users for flights from John Wayne (Santa Ana) to Louisville are Southwest and American Airlines. With an average price for the route of $576 and an overall rating of 7.9, Southwest is the most popular choice. American Airlines is also a great choice for the route, with an average price of $475 and an overall rating of 7.1.

  • How does KAYAK find such low prices on flights from John Wayne (Santa Ana) to Louisville?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from John Wayne (Santa Ana) to Louisville.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from John Wayne (Santa Ana) to Louisville?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Louisville from John Wayne (Santa Ana) is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from John Wayne (Santa Ana) to Louisville?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Louisville with an airline and back to John Wayne (Santa Ana) with another airline. Booking your flights between John Wayne (Santa Ana) and SDF can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from John Wayne (Santa Ana) to Louisville?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Louisville from John Wayne (Santa Ana) up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Santa Ana to Louisville

 
See real verified KAYAK customer reviews for airlines flying from John Wayne (Santa Ana) to Louisville. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Santa Ana to Louisville? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
SouthwestOverall score based on 4246 reviews
8.6Crew
7.5Entertainment
8.1Boarding
7.0Food
8.0Comfort
Airline reviews

Flight was delayed, full flight and I had to change gates. Southwest flights are always late later in the day.

4.0 OkaySteven, Jun 2026
ONT - LAS
Read more Southwest reviews

Flight was delayed, full flight and I had to change gates. Southwest flights are always late later in the day.

Was fine, delayed and feels like southwest is always late

The entire experience from boarding to landing was amazing! The crew were very friendly. Will definitely be back.

Delayed flight, lack of information, boarding process is a mess as is the carryon luggage causing issues when leaving the plane….just a poor experience.

Comfortable. Easy. No problems. Just wish they had gf options for snacks.

The crew was very kind and made going to Hawaii relaxing and fun to look forward to! Thank you Southwest for a pleasant flight!

The seats were a bit cramped and worn, but otherwise okay.

Great flight, 47 passengers on a 180 seat plane. Stewardess was pleasant and cheerful.

Since the flight wasn’t full, we had some extra room. Crew was great

The 700 model seating is too tight both seat size & leg room

The gate got changed several times and the flight was delayed over an hour. Awful experience

It was an older plane. First Class was not especially roomy or comfortable. It was a short flight so there were no meal but they did offer mixed nuts which used to be normal but now is rare. Crew member was very polite and professional.

No Snacks or Entertainment. The flight was short, snacks should still be given.

Our flight was 1.5 hours delayed. There was no weather for the inbound flight, so I don't understand why. This meant a VERY late arrival and only a quick nap before my morning flight.

Everything was fine. Flight boarded and departed on time. Seating was spacious enough for my carryon to fit under the seat in front of me. No complaints at all. Flight even arrived early.

The flight encountered a delay exceeding 4 hours. The food voucher issued was valued at $12, insufficient to cover our meal expenses. Consequently, I was unable to take my medication, leading to a drop in blood sugar levels and exacerbating my anxiety.

Boston ticket agent Cheryl Porter is WONDERFUL. Our Iberia flight to Barcelona was cancelled the morning we were scheduled to leave and Cheryl was our super hero - she found us seats on a flight to London and on to Barcelona. Truly a “can-do” attitude which we appreciated so much after the Iberia ticket agents told us there was “absolutely nothing they could do”. (As did the customer service agents at Iberia’s call center) Ms Porter is truly a wonderful person who genuinely cares about travelers!

Flights were on time. That's the main consideration since I had to change planes. The entertainment was whatever you bring with you and the food (in Economy) is non-existant. Neither of those was a surprise.

The gate crew did try to help, however they lacked the information as to whether the flight will operate or not. Being delayed 6 hours and in a limbo on whether the flight will operate or not is not fun. The airline having staffing issues is not encouraging at all.

Nothing wrong on this flight but nothing special. It was oversold and they had to bump people which is always bad.

Everything you need to know for your flight from Santa Ana to Louisville

Information on your arrival and departure airports