$379 Find Cheap Flights from Panama City to John Wayne (Santa Ana) - Compare and Save

In the last 5 days, the lowest price for a flight from Panama City to John Wayne (Santa Ana) was $379 for a one-way ticket and $799 for a round-trip.

Yes, you'll most likely have to show a valid passport before boarding the plane in Panama City and on arrival in John Wayne (Santa Ana).

Panama City and John Wayne (Santa Ana) are both served by 1 main airport. You will leave Panama City from Panama City Tocumen Intl and will be arriving at Santa Ana J. Wayne/Orange Cnty.

We unfortunately don’t have that data for this specific route.

KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Panama City to John Wayne (Santa Ana).

KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to John Wayne (Santa Ana) from Panama City is likely to change within 7 days, so travelers know whether to wait or book now.

Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to John Wayne (Santa Ana) with an airline and back to Panama City with another airline. Booking your flights between Panama City and SNA can sometimes prove cheaper using this method.

Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to John Wayne (Santa Ana) from Panama City up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.