$55 Find Cheap Flights from South Carolina to Indiana

1 adult

KAYAK searches hundreds of travel sites at once for deals on flights to Indiana

Travelers love KAYAK
41,299,237 searches in the past 7 days on KAYAK

Save 22% or moreCompare multiple travel sites with one search.

Track pricesNot ready to book? Create a price alert for when prices drop.

Bundle and saveSave money when you bundle your flight + hotel.

Filter your dealsChoose cabin class, free Wi-Fi and more.

Useful Info
Useful Info

Good to know

Low seasonJanuary
High seasonMay
Cheapest flight$55
Best time to beat the crowds with an average 0% drop in price.
Most popular time to fly and prices are also 1% lower on average.
Flight from Charlotte to Chicago O'Hare Airport

FAQs for booking flights from South Carolina to Indiana

  • How does KAYAK find such low prices on flights from South Carolina to Indiana?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from South Carolina to Indiana.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from South Carolina to Indiana?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from South Carolina to Indiana is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from South Carolina to Indiana?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from South Carolina to Indiana with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from South Carolina to Indiana?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from South Carolina to Indiana up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest day to fly to Indiana?

    Based on KAYAK data, the cheapest day to fly to Indiana is Saturday where round-trip tickets can be as cheap as $67. On the other hand, the most expensive day to fly is Sunday, where round-trip prices are $430 on average.

  • What is the cheapest time of day to fly to Indiana?

    The cheapest time of day to fly to Indiana is generally in the evening, when round-trip flights cost $153 on average. Morning departures are around 100% cheaper than evening flights, on average. The most expensive time of day to fly to Indiana is generally at night, which is peak travel time and where the average cost of a ticket is $361.

  • What is the cheapest flight to Indiana?

    The cheapest ticket to Indiana from South Carolina found in the last 72 hours was to Indianapolis, at $58 round-trip. The most popular route is Charleston (CHS) to Indianapolis (IND) and the cheapest round-trip airline ticket found on this route in the last 72 hours was $58.

  • What is the cheapest month to fly from South Carolina to Indiana?

    The cheapest month for flights from South Carolina to Indiana is August, when tickets cost $245 (return) on average. On the other hand, the most expensive months are March and April, when the average cost of round-trip tickets is $756 and $477 respectively.

  • How far in advance should I book a flight from South Carolina to Indiana?

    To get a below average price on the flight from South Carolina to Indiana, you should book around 4 weeks before departure. For the absolute cheapest price, our data suggests you should book 18 weeks before departure.

  • How long is the flight to Indiana?

    An average nonstop flight from South Carolina to Indiana takes 3h 31m, covering a distance of 555 miles. The shortest route is Charlotte (CLT) to Cincinnati (CVG) with an average flight time of 1h 19m.

  • What are the most popular destinations in Indiana?

    Based on KAYAK flight searches, the most popular destination is Chicago (73% of total searches to Indiana). The next most popular destinations are Indianapolis (8%) and Louisville (6%). Searches for flights to Cincinnati (5%), to Dayton (3%) and to South Bend (2%) are also popular.

Top 5 airlines serving from South Carolina to Indiana

Need help choosing which airline to fly with from South Carolina to Indiana? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
DeltaOverall score based on 7934 reviews
7.9Comfort
7.3Food
8.5Crew
7.9Entertainment
8.2Boarding
Airline reviews

Delta is my preferred airline. I've traveled with them for years. On time in most cases, good communication, easy to use app. Most planes are pretty nice. I was on a CRJ 700/900 however, which was pretty badly aged inside and needed a refresh. No infotainment, unreliable wifi, best to download before boarding or bring a book. Food choices are really just snacks on this flight, nice variety but about what you'd expect. Great staff and prompt in departure and early arrival too. Overall quite satisfied.

8.0 ExcellentFredrick, Apr 2025GSO - DTW
Read more Delta reviews

Delta is my preferred airline. I've traveled with them for years. On time in most cases, good communication, easy to use app. Most planes are pretty nice. I was on a CRJ 700/900 however, which was pretty badly aged inside and needed a refresh. No infotainment, unreliable wifi, best to download before boarding or bring a book. Food choices are really just snacks on this flight, nice variety but about what you'd expect. Great staff and prompt in departure and early arrival too. Overall quite satisfied.

Crew was friendly Love the entertainment in the seat head rest.

Delta flight was on time, seats were comfortable, and crew was nice.

This had nothing to do with Delta… The flights were on time and flawless. The service was excellent. We purchased seats in (aisle/middle) comfort plus since this was a cross country flight. Unfortunately, the woman seated at the window was 300+ pounds and, as might be expected, covered up about a third of the middle seat also. there was absolutely nothing that Delta could have done about that… I just don’t know what the answer should be. If you purchase a seat, you should should be able to use the entire seat and not just the portion that someone else is not sitting/oozing in. Disappointing…there should be something that could be done….I'm just not sure what solution could be.

Delayed take-off. Very small plane so very scary with lots of bumps during the flight. Would never fly Delta on short flights in small 80 seaters plane again! Felt relieved when landed.

The worst part was I was NOT allowed in the lounge even though I was holding a first class ticket and have a premium American Express card. I have flown Business or First Class with many airlines. Delta is the ONLY one who does not extend this courtesy to anyone except people who hold the very expensive American Express card. As a result, I won’t fly Delta if I have any other choice.

A little bumpy ride . No food was being provided due the the turbulence. That was ok it was a short flight to my standards.

Simply outstanding. Their new lounge for Delta One customers is a cut above the rest.

The Dekta Rep that checked us in was great. She's very personable, pleasant, and can tell she enjoys her job.

The plane was old with small storage areas that had problems closing/latching and not enough storage for everyone, and worn, damaged seats. Service was great but feel a little unsafe on such well used planes.

A bit rush for transit. Food and entertainment are not available

Multiple delays and not straight answer from the United team

Stewardess spilled orange juice on my clothes/seat no help no apology just threw napkins at me to clean the mess up. Not Happy.

Smooth flight. Boarding was chaotic. Could not hear the gate agent over the intercom. People were lined up in the wrong lines. Groups one and two were told to board through line one and group 3 through line 2. All very confusing. Once in the air, the flight was smooth. There was no entertainment option on this aircraft, even though it was a larger aircraft.

The plane pushed back from the gate on time. However, it stopped on the ramp, and we waited for over 20 minutes before the aircraft pulled back to the gate. Apparently, something of importance had to be removed from the aircraft by the gate agent. I found this to be odd. The delay was not significant, but I felt that whatever was on the aircraft that had to be taken off, should’ve been done before we pushed back from the gate.

Electric plugs didn't work. Entertainment system wasn't working

The design of the light switch on the arm rest is ridiculous.

Smooth boarding process. Early departure, smooth flight, early arrival. The entertainment package has very good recent movie options. The flight crew were friendly and professional.

leg space better than expected. two washrooms for one plane isn't enough.

The gate attendant let me walk right by her with a bag too big for the overhead compartment

Easiest flights I’ve ever taken. Plane was comfortable without overly crowded seating.

Terrible. Still have not received the refund from them. They sent it to some account that I don't even know. Spoke with costumer service and they are unable to help.

I didn’t like it at all. I miss my second flight because of the delay on Allegiant Air now I m stuck in MCO.

Good, but a bit late on take off after loading. Don't like charging for carry ons!

First time flying with them and will definitely fly again in the future. Crew was so nice and friendly, fought was seamless. They are simple planes, no entertainment, but it’s fine for a short flight or if you have personal devices Rates are competitive, and they did so well with keeping the flight on time after a tropical storm, where other airlines had delays and cancellations.

They boarded passengers that sat in the back of the plane first, making boarding very efficient.

I didn't even take this flight. My plans changed and I couldn't get ahold of customer service and the website kept breaking down during the attempt to change the flight. I wound up taking another airline entirely and eating the cost.

The worst flying experience ever 3 delays. No accommodations. Had to deboard the plane after being delayed.

Posted a 20minute delay but didn’t delay at all. Caused boarding issues and confusion. Also, didn’t release baggage. Took over an hour and 20 minutes to get luggage.

Flight was good, boarding was a breeze, flight attendants were friendly and professional. There was a medical issue with another passenger and the crew handled it in a calm and professional way.

Several delays. Next flight was worse. Did not arrive home until 2am PT

Very helpful ground crew after an earlier flight delay and being rebooked on a different flight.

Everything about the flight was lovely…We left early, arrived early, cabin crew were efficient and helpful. Flight was easy and most pleasant.

First world problems, but still… We were seated in first class and asked for a cocktail on a very short, 50 minute flight. After our drink order was taken, a half hour went by, and we noticed that every other person in the small plane had been served except for us. We got up to ask about it, the drinks finally came, then were taken away three minutes later since the flight was so short. Really strange situation, on the other hand, we were in Utah.

We missed our flight. The boarding pass had the wrong gate and by the time we received the text from Kayak, our flight was already gone. I’ll never use Kayak again and will go direct to the airlines in the future.

Boarding took forever, the plane was cramped and cold, and the seatbelt song came on constantly throughout the red eye flight with a loud pre-recorded message playing each time

Cabin felt crammed Snacks are lame But crew was super efficient getting us out on time despite delay

Took off on time and successfully avoided weather that looked to be a problem along the way

There were five broken seats on the plane. The crew was very rude in telling people they had to get off the plane and get a flight the next day. No call for volunteers, but telling people they had to get off. One woman was flying with her elderly mother and daughter and was told she had to leave or all three had to leave. Fortunately, a volunteer offered to stay. The situation was handled poorly.

The flight to Tokyo AA61 took off about two hours late, but then had to turn back. By that time the crew had to be replaced. Then they kept promising to take off in an hour, then in 3, then switch to the next day.

Not having it be changed after we bought the flight tickets from a direct flight getting in at a reasonable time to a connecting flight red eye of 9 hours, so that we would lose our 35 dollars in nonrefundable insurance would've been great! Our country really does need low-cost carrier options, but this type of "service" ain't it. Fortunately, had a little better success with them flying to and from San Juan PR last month at least.

All was good expecting the seats need a bit of cushion. Besides that I can’t complain.

You get what you pay for, and the flights went smoothly. There’s no reclining chairs, no screens, And there isn’t always wifi, but the plane was clean and staff was friendly and the takeoff/landing were smooth.

The only positive is that the flight made it both ways. Getting charged for every little thing after the cost of the ticket itself is comical, considering how the plane and services are as bottom-tier as possible. The self check-in kiosks are useless. It’s nice to think that you can print your boarding pass, tag your checked bag, and then just drop it off. But no, they still make you go through the line once you finish- what’s the point of the self check-in then? Any questions for the staff seem like the biggest inconvenience and were met with condescending responses. This was my first and now last time ever flying with Spirit. After all the extra costs, subpar plane and staff, I see no value. I’d rather drive the 13 hours than give Spirit another dime.

The flight was fine however what started as a reasonable priced ticket could have become an overpriced ticket with additional charge for carry on as well as checked bag $79 per bag per person each way. Additional charge for choosing one’s seat, additional charge for beverage and snack, we were on what was described as a new plane yet there were no audio/visual on the jet. A bare bones service but not at a bare bones price. Will think twice before flying Spirit again. 😕

Flight was delayed a bit, but that was expected (and updated), so really not bad at all for the price. Could’ve used one less email asking me to upgrade my seat; otherwise no significant complaints

I love Spirit. New aircraft, great cabin service, the airfares are low cost which helps me visit my hospitalized daughter anytime I can without paying a fortune.

Flight was 2hours late they had no crew or the pilot.

I paid for streaming wifi and the connection was poor.

We had an 8 hr delay so it was not good

Book cheap flights from South Carolina to Indiana

Recent round-trip flight deals

6/5Thu
nonstopFrontier
2h 25mCLT-ORD
6/8Sun
nonstopFrontier
2h 07mORD-CLT
$100
6/26Thu
nonstopFrontier
2h 25mCLT-ORD
6/29Sun
nonstopFrontier
2h 07mORD-CLT
$110
8/16Sat
nonstopAmerican Airlines
1h 41mCLT-IND
8/20Wed
nonstopAmerican Airlines
1h 42mIND-CLT
$139
5/29Thu
1 stopSpirit Airlines
12h 48mCLT-ORD
6/2Mon
1 stopSpirit Airlines
7h 53mORD-CLT
$148
5/28Wed
1 stopSpirit Airlines
15h 22mCLT-ORD
6/2Mon
1 stopSpirit Airlines
6h 16mORD-CLT
$153
7/25Fri
nonstopAmerican Airlines
2h 38mSAV-ORD
8/1Fri
nonstopAmerican Airlines
2h 12mORD-SAV
$157
8/16Sat
1 stopDelta
5h 47mCLT-IND
8/20Wed
1 stopDelta
3h 32mIND-CLT
$177
5/24Sat
1 stopDelta
4h 42mCLT-ORD
5/25Sun
1 stopDelta
5h 58mORD-CLT
$197
7/25Fri
nonstopUnited Airlines
2h 20mGSP-ORD
7/26Sat
nonstopUnited Airlines
1h 59mORD-GSP
$202
6/3Tue
1 stopUnited Airlines
4h 44mGSP-ORD
6/10Tue
nonstopUnited Airlines
2h 07mORD-GSP
$205

Search by stops

Search by airline

Search by price

Recent one-way flight deals

6/8Sun
nonstopFrontier
2h 25mCLT-ORD
$55
5/22Thu
nonstopFrontier
2h 33mCLT-ORD
$56
5/30Fri
1 stopSpirit Airlines
6h 15mCLT-ORD
$69
5/29Thu
nonstopSpirit Airlines
1h 41mCLT-IND
$73
7/7Mon
nonstopAmerican Airlines
2h 38mSAV-ORD
$79
5/24Sat
nonstopAmerican Airlines
2h 13mCLT-ORD
$81
5/24Sat
1 stopDelta
5h 58mCLT-MDW
$99
5/24Sat
1 stopDelta
4h 46mCLT-ORD
$99
5/31Sat
nonstopUnited Airlines
2h 36mCLT-ORD
$105
6/2Mon
nonstopUnited Airlines
2h 34mSAV-ORD
$114

Search by stops

Search by airline

Search by price

Last minute flights from South Carolina to Indiana

Last minute flight, train and bus deals

5/5Mon
multi-stop
6h 06mCLT-ORD
6/1Sun
nonstop
2h 07mORD-CLT
$159
5/3Sat
multi-stopFrontier
5h 50mCLT-ORD
5/29Thu
nonstopFrontier
2h 16mORD-CLT
$184
5/5Mon
multi-stopSpirit Airlines
6h 06mCLT-ORD
6/2Mon
multi-stopSpirit Airlines
6h 16mORD-CLT
$185
5/5Mon
multi-stopSpirit Airlines
6h 06mCLT-ORD
5/29Thu
multi-stopSpirit Airlines
9h 02mORD-CLT
$191
5/3Sat
nonstopAmerican Airlines
2h 09mGSP-ORD
5/5Mon
multi-stopAmerican Airlines
5h 07mORD-GSP
$276
5/1Thu
nonstopAmerican Airlines
2h 11mGSP-ORD
5/3Sat
nonstopAmerican Airlines
1h 54mORD-GSP
$283
5/3Sat
multi-stopDelta
5h 09mGSP-ORD
5/5Mon
multi-stopDelta
5h 19mORD-GSP
$286
5/1Thu
multi-stopDelta
7h 11mGSP-ORD
5/3Sat
multi-stopDelta
4h 08mORD-GSP
$303
5/2Fri
multi-stopUnited Airlines
7h 18mCAE-ORD
5/18Sun
multi-stopUnited Airlines
4h 22mORD-CAE
$355
5/2Fri
multi-stopUnited Airlines
4h 40mCAE-ORD
5/18Sun
nonstopUnited Airlines
2h 09mORD-CAE
$399

Search by stops

Search by airline

Search by price

Everything you need to know for your flight to Indiana

Cabin class types available on flights to South Carolina

Cabin classes available on flights to South Carolina. Prices are the lowest found on KAYAK over the last 7 days. Price and availability is not guaranteed.

Not what you’re looking for? Find thousands of other hotels, flights, car rentals and package deals with KAYAK.