$113 Find Cheap Flights from North America to Panama City

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight to Panama City departing on 12/17. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$209
Overall average: $438
United Airlines
Thu 12/18Sun 12/21
ORD - ECP • Non-stop
Cheapest one-way
$113
Typical prices: $114-$241
United Airlines
Wed 12/17
IAH - ECP • Non-stop
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Flight Deals

Cheap Flights from North America to Panama City

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from North America to Panama City that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from North America to Panama City

Thu, Dec 18 - Sun, Dec 21
United Airlines Logo
10:45 am - 1:27 pmORD-ECP
2h 42mnonstop
United Airlines Logo
2:10 pm - 4:54 pmECP-ORD
2h 44mnonstop
$209United Airlines
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Wed, Jan 21 - Wed, Jan 28
United Airlines Logo
10:06 am - 12:02 pmIAH-ECP
1h 56mnonstop
United Airlines Logo
6:30 am - 8:46 amECP-IAH
2h 16mnonstop
$225United Airlines
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Mon, Dec 22 - Sat, Dec 27
United Airlines Logo
2:20 pm - 4:10 pmIAH-ECP
1h 50mnonstop
United Airlines Logo
6:15 am - 8:31 amECP-IAH
2h 16mnonstop
$227United Airlines
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Thu, Dec 18 - Sun, Dec 21
Delta Logo
6:04 pm - 11:06 pmORD-ECP
5h 02m1 stop
Delta Logo
6:00 am - 11:27 amECP-ORD
5h 27m1 stop
$229Delta
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Sat, Jan 17 - Wed, Jan 21
American Airlines Logo
7:00 am - 1:10 pmMSP-ECP
6h 10m1 stop
American Airlines Logo
1:34 pm - 10:08 pmECP-MSP
8h 34m1 stop
$237American Airlines
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Sat, Jan 17 - Wed, Jan 21
American Airlines Logo
7:00 am - 5:30 pmMSP-ECP
10h 30m2 stops
American Airlines Logo
7:02 am - 2:56 pmECP-MSP
7h 54m1 stop
$242American Airlines
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Tue, Jan 6 - Wed, Jan 7
Delta Logo
2:11 pm - 7:50 pmIAH-ECP
5h 39m1 stop
Delta Logo
10:01 am - 3:16 pmECP-IAH
5h 15m1 stop
$245Delta
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Sat, Mar 14 - Wed, Mar 18
United Airlines Logo
8:45 am - 11:19 amORD-ECP
2h 34mnonstop
United Airlines Logo
2:10 pm - 4:50 pmECP-ORD
2h 40mnonstop
$245United Airlines
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Fri, Feb 27 - Wed, Mar 4
Southwest Logo
5:15 pm - 10:30 pmORD-ECP
5h 15m1 stop
Southwest Logo
8:00 am - 12:15 pmECP-ORD
4h 15m1 stop
$249Southwest
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Tue, Jan 20 - Fri, Jan 23
Southwest Logo
10:00 am - 6:10 pmHOU-ECP
8h 10m2 stops
Southwest Logo
3:45 pm - 10:40 pmECP-HOU
6h 55m1 stop
$252Southwest
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Useful Info

Good to know

Low seasonJanuary
Cheapest flight$113
Best time to beat the crowds but there is an average 1% increase in price.
Most popular time to fly with an average 7% increase in price.
Flight from Houston George Bush Airport to Panama City

FAQs for booking flights from North America to Panama City

  • How does KAYAK find such low prices on flights from North America to Panama City?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from North America to Panama City.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from North America to Panama City?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Panama City from North America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from North America to Panama City?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Panama City with an airline and back to North America with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from North America to Panama City?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Panama City from North America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 5 airlines serving from North America to Panama City

 
Need help choosing which airline to fly with from North America to Panama City? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
SouthwestOverall score based on 4254 reviews
8.0Comfort
8.6Crew
8.1Boarding
7.5Entertainment
7.0Food
Airline reviews

No delays and arrived to destination 30 min early. Staff was super friendly.

10.0 ExcellentIlevba, Nov 2025DCA - DAL
Read more Southwest reviews

No delays and arrived to destination 30 min early. Staff was super friendly.

San Diego airport is brand new, spacious, airy and very smooth checkin at SW baggage drop.

It was rough. The staff was unprofessional, the choice of on board drinks terrible, it was cramped in space at every airport, they always ran out of overhead bin space so they pressured people to check bags for free or we couldn’t leave on the plane— so I did check my bag to help, and they nearly lost my bag. My bag did not arrive on the luggage belt, another man on my flight and I had to waste our time going to the baggage office to search for our bags. I would only fly southwest again if it was my last choice. Also, my flights were consistently delayed over and over again— at one point they straight up told us we were waiting for the pilot to arrive.

Crew could have been friendlier, maybe I'm spoiled by SW crews. In flight wifi was good. Would be nice to have more food offerings on a 4 plus hour flight

Had to get off plane from prior flight even though I had to reboard same plane to continue to my final destination.

Everything a cheap airline should be at normal airline rates.

Plane crashed into a bus or some other vehicle on the ground while pulling out of the gate. No injuries, but wing tip was damaged and returned to gate for “maintenance issues” and we departed 5 hours later because the plane went out of service and new plane was flown in from a nearby airport, Midway.

Ever since Southwest starting charging for bags, passengers don't want to pay to check their bags, so the gate agents have to beg people to check their roller bags now because there's "not enough space". This was a terrible business move by Southwest.

Full cans of soda would be nice. A choice between two snacks would be appreciated.

Tried watching free movie and it kept freezing so I couldn’t finish.

First, Delta needs more flights to/from Miami. Second, a 1000pm leaving at 1230pm is unacceptable from their biggest airport world hub. Another aircraft could have been used such as the aircraft scheduled to be used in the morning for that exact same route. Yes, I did get me there but the lack of sleep the next day didn't help me enjoy my entire trip since I was busy with activities during the weekend. This can be and is expected from Spirit (going bankrupt) and Frontier (despite they're nickel and dimers). But from Delta's World Hub? That's totally unacceptable!

This flight was straightforward and without difficulty. Service was OK, but I continue to be underwhelmed by level of attention given to Sky Priority passengers.

It would’ve been nice for all that money to have a more substantial snack for free. I remember once upon a time getting a very nice turkey sandwich with Swiss cheese on whole wheat bread for no charge along with a drink. I guess those days are gone. it’s a little insulting being given a cookie or a bag of baked chips Going forward I’ll just bring my own.

Our flight from SFO to MSP was right on time on 11/15/2025. No delays. As we approached MSP at about 8 pm, we circled in the air until 8:40 pm so I don't call that efficient for MSP. I think the captain should announce the delay and why. (as if we all don't know that we are just circling around the area, slowing down, speeding up, slowing down.) Thank you. Marilyn Fischer

Service in business class was not impressive. I ordered coffee with dinner and then watched other people get 2 refills before I got my 1 cup of coffee, and only after I pressed the attendant button overhead. Furthermore, the seats in the forward cabin need maintenance on this 737-800: the upholstery is detaching from the seat frame, at least on the backs of seats 1C, 1D.

I truly love flying with Delta. They have always treated me with the upmost respect

Our flight attendant in FIRST CLASS was one of the worst I’ve ever had. She was not at all pleasant, nor particularly good at her service.

The flight was an hour and a half late departing which was inconvenient

The flight was great. The gate location was way to far away!!!

The flight attendant in first class was beyond rude and didn't care at all about her job. AND the gate agent was even worse than the flight attendant for rudeness. She was awful.

Quick and seamless boarding. No entertainment but fast Starlink wifi for this short trip and the staff was really friendly.

We boarded late. The crew at the airport was dismissive. The seat cushion on the plane was uncomfortable.

Very thoughtful flight attendant offered me water immediately since I had run to make my connection.

Door to door, the crew and staff were amazing. It was a stressful travel day with delays, but they were focused on customers and doing what they could to get us to our destinations.

I dread trans-Pacific flights. They are very long. This was my first time on Universal, and it was my best crossing ever. The staff were professional, the hospitality was great, and the food was delicious. The entertainment system filled the long flight hours. I will seek out Universal flights from now onwards. 🙂

United has come a long way, it’s been a fantastic experience traveling with them.

Even though we were delayed, we were able to make our connection

Starlink wifi on the Embraer E175 is an excellent experience. I was able to connect and work from IAD all the way to approach into BTV.

Great crew, excellent landing, good food. Over all great experience. Thank you!

Older aircraft, no meal, only food was for purchase. Not impressed United.

Delays to take off and to leave the plane after landing added a lot of time to this flight.

It was a red eye flight, so no meals were provided, but it was fine with snacks. The seats felt cramped and almost too narrow.

We didn't take off until an hour after we boarded.

Wish they had the seat-back video screens for watching movies or playing games.

Very good but wish they had the seat-back video screens for movies & games

The delayed flight was awful and moving the departure gate twice was annoying

Flight was delayed not sure why no explanation given and no apologies either. Otherwise the flight was fine

Flight from Miami to Lima was very good, like the free WiFi to get movies and TV.

While waiting to claim my checked luggage, I discovered the airline had lost it. After a long wait and inquiries, I discovered it was on another flight. Fortunately, the airline finally sent my luggage home.

Flight delays numerous times. Everytime we would get close to boarding it would be delayed again. Strung along the entire time.

Excellent flight and even arrived 23 min early. No entertainment , or wi fi on board, but I downloaded a couple of movies beforehand which kept me entertained. Really like flying Allegiant airlines.

WE were delayed about an hour and never any communications from the employees working the gate. We also were moved to a total of three gates.

I love how they show love to their customers and care about them too.

I liked how when I got on board how fast we ended up taking off but what I truly disliked was how uncomfortable the seats were. There was truly never a time that I could ever get comfortable during both of my flights. The seats could get away during shorter flights but flights 3 hour plus makes it hard to enjoy.

The crew was great and the flight was very smooth. Can’t really judge food since I did not get any because it costs money. The seat was comfortable for what we bought. Thanks!

Crew was great. No entertainment and food and beverage was for purchase only, even water

It was canceled. The flight wasn’t rescheduled, everyone had to figure out their own new arrangements. They said we would get refunded our original fare and receive an additional $150. We received links for $100 only and they expired before we could activate them.

The plane had originated in Las Vegas at 6:30 in the morning and flew to Moline where we boarded. The flight left around 12:30 PM and there were no boxed snacks available and many of the alcoholic beverages were unavailable. I would find it hard to believe that that many of the passengers coming from Las Vegas at 6:30 in the morning, drank and ate that much of the items. I can only come to the conclusion that someone failed to stock the plane for the round-trip. This is a huge revenue failure for the airline and disappointment for the passengers. The flight crew did not seem happy to be there and did not engage with passengers. Allegiant you can do better.

They did not let my husband on the plane with our service animal at the last minute. Do NOT fly this airline with a service animal!

Tight! Seats are not designed for those of us who wear extra-large clothes.

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