$454 Find cheap flights from Rome to John Wayne (Santa Ana)

In the last 3 days, the lowest price for a flight from Rome Fiumicino Airport to Santa Ana was $454 for a one-way ticket and $690 for a round-trip.

Yes, you’ll need a passport to travel to Santa Ana from Rome.

We unfortunately don’t have that data for this specific route.

oneworld, SkyTeam, and Star Alliance are the airline alliances operating flights between Rome and Santa Ana, with Star Alliance being the most commonly used for this route.

KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Rome to Santa Ana.

KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santa Ana from Rome is likely to change within 7 days, so travelers know whether to wait or book now.

Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Santa Ana with an airline and back to Rome with another airline. Booking your flights between Rome and SNA can sometimes prove cheaper using this method.

Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santa Ana from Rome up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.