SNA - BUF

$226 Find Cheap Flights from Santa Ana to Buffalo

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Santa Ana to Buffalo departing on 4/7. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Buffalo

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santa Ana to Buffalo, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santa Ana to Buffalo, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$371
Delta
Tue 5/5Wed 5/13
SNA - BUF • 1 stop
Cheapest one-way
$226
Typical prices: $380-$545
American Airlines
Tue 4/7
SNA - BUF • 1 stop
Top airlines
Cheapest • from $351 (round-trip)
Best reviews • 8.0 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Santa Ana and Buffalo. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Cheapest • Avg $542 (round-trip)
Shortest trip • 7h 11m (one-way)
Insights
Insights
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Buffalo!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Santa Ana to Buffalo (SNA-BUF)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Santa Ana to Buffalo that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Santa Ana to Buffalo

Tue, May 5 - Wed, May 13
Delta Logo
1:12 pm - 10:39 pm
SNA
-
BUF
6h 27m
1 stop
Delta Logo
4:55 pm - 10:22 pm
BUF
-
SNA
8h 27m
1 stop
$371Delta
Thu, May 7 - Tue, May 12
Southwest Logo
7:50 pm - 7:50 am
SNA
-
BUF
9h 00m
2 stops
Southwest Logo
3:10 pm - 9:45 pm
BUF
-
SNA
9h 35m
2 stops
$372Southwest
Wed, Apr 15 - Tue, Apr 21
Southwest Logo
11:25 am - 10:50 pm
SNA
-
BUF
8h 25m
1 stop
Southwest Logo
3:10 pm - 9:45 pm
BUF
-
SNA
9h 35m
2 stops
$378Southwest
Wed, May 6 - Wed, May 13
Southwest Logo
7:40 pm - 7:50 am
SNA
-
BUF
9h 10m
2 stops
Southwest Logo
3:10 pm - 9:50 pm
BUF
-
SNA
9h 40m
2 stops
$380Southwest
Wed, May 6 - Wed, May 13
Southwest Logo
7:50 pm - 7:50 am
SNA
-
BUF
9h 00m
2 stops
Southwest Logo
3:10 pm - 9:45 pm
BUF
-
SNA
9h 35m
2 stops
$383Southwest
Sat, May 9 - Wed, May 13
Delta Logo
1:50 pm - 11:59 pm
SNA
-
BUF
7h 09m
1 stop
Delta Logo
4:55 pm - 10:22 pm
BUF
-
SNA
8h 27m
1 stop
$390Delta
Thu, Apr 16 - Tue, Apr 21
Southwest Logo
7:40 pm - 7:50 am
SNA
-
BUF
9h 10m
2 stops
Southwest Logo
3:10 pm - 9:45 pm
BUF
-
SNA
9h 35m
2 stops
$391Southwest
Tue, May 5 - Wed, May 13
Delta Logo
1:12 pm - 10:39 pm
SNA
-
BUF
6h 27m
1 stop
Delta Logo
4:55 pm - 10:29 pm
BUF
-
SNA
8h 34m
1 stop
$393Delta
Thu, May 7 - Tue, May 12
American Airlines Logo
7:20 pm - 10:51 am
SNA
-
BUF
12h 31m
2 stops
American Airlines Logo
1:34 pm - 9:14 pm
BUF
-
SNA
10h 40m
1 stop
$395American Airlines
Mon, May 4 - Tue, May 12
Delta Logo
9:20 pm - 2:52 pm
SNA
-
BUF
14h 32m
2 stops
Delta Logo
4:55 pm - 10:29 pm
BUF
-
SNA
8h 34m
1 stop
$398Delta
Booking Insights

KAYAK's insights & trends for Santa Ana to Buffalo flights

Get data-powered insights and trends into flights from Santa Ana to Buffalo to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from John Wayne (Santa Ana) to Buffalo?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from John Wayne (Santa Ana) to Buffalo were found on United Airlines ($351) and Delta ($371).

Good to know

Cheapest flight$226
Flight from John Wayne (Santa Ana) to Buffalo

When to book flights from Santa Ana to Buffalo

Are your dates flexible? Find out the best times to travel from Santa Ana to Buffalo based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from John Wayne (Santa Ana) to Buffalo

  • What is the cheapest flight from Santa Ana to Buffalo?

    In the last 3 days, the lowest price for a flight from Santa Ana to Buffalo was $229 for a one-way ticket and $351 for a round-trip.

  • Do I need a passport to fly between John Wayne (Santa Ana) and Buffalo?

    Even though you are not required to have a passport, keep in mind that an official ID is needed to board the airplane.

  • Which aircraft models fly most regularly from John Wayne (Santa Ana) to Buffalo?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from John Wayne (Santa Ana) to Buffalo?

    oneworld is the only airline alliance operating flights between John Wayne (Santa Ana) and Buffalo.

  • Which is the best airline for flights from Santa Ana to Buffalo, Southwest or American Airlines?

    The two airlines most popular with KAYAK users for flights from Santa Ana to Buffalo are Southwest and American Airlines. With an average price for the route of $542 and an overall rating of 8.0, Southwest is the most popular choice. American Airlines is also a great choice for the route, with an average price of $606 and an overall rating of 7.1.

  • How does KAYAK find such low prices on flights from John Wayne (Santa Ana) to Buffalo?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from John Wayne (Santa Ana) to Buffalo.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from John Wayne (Santa Ana) to Buffalo?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Buffalo from John Wayne (Santa Ana) is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from John Wayne (Santa Ana) to Buffalo?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Buffalo with an airline and back to John Wayne (Santa Ana) with another airline. Booking your flights between John Wayne (Santa Ana) and BUF can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from John Wayne (Santa Ana) to Buffalo?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Buffalo from John Wayne (Santa Ana) up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Santa Ana to Buffalo

 
See real verified KAYAK customer reviews for airlines flying from Santa Ana to Buffalo. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Santa Ana to Buffalo? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
SouthwestOverall score based on 4320 reviews
8.6Crew
7.5Entertainment
7.0Food
8.1Boarding
8.0Comfort
Airline reviews

The problem with the seat assignments is that there were a lot of rows in the front that were empty but my row at the back was full. Just not so pleasant.

8.0 ExcellentTobin, Mar 2026
SJC - BUR
Read more Southwest reviews

The problem with the seat assignments is that there were a lot of rows in the front that were empty but my row at the back was full. Just not so pleasant.

Good but I prefer choose your own seat. With the new assigned seats they should board from the back I see no advantage to this new boarding. Just like every other airline

Flight boarded late after announcing on time boarding. Flight arrived only a little late despite late departure. Had trouble connecting to WiFi

The Southwest experience has definitely taken a dive from its early days. You can no longer deferentiate from other airlines. Air travel is too expensive. Southwest is no longer budget friendly. They have lost me as a loyal customer.

The charges were ridiculous for an hour flight and the turbulence was very scary.

The seats are now more narrow. I paid for front row the seats in the front are even more narrow than before.

The wifi on the plane is great. The only issue that I have is that I prefer an aisle seat and on my trips this week, I was either in the middle or window. If we can work to secure aisle seating, I will be thrilled. Nice trip.

Great flight but super high price. Glad it was a business trip and not personal

3 hour delay. Had to change plans and was still delayed.

We got exit row seats both flights. Everything was running on time

Our flight was delayed 3 times and this is why I am giving such low reviews. Everything else was okay but being in the airport at 4:30pm for my initial flight at 7pm to not leave until after 9:30pm is insane,

The crew was excellent and overall the flight was good. No complaints.

Good crew and flight was on time. It’s a small plane with limited overhead luggage space. They said the overhead space was full and I had to check my bag. There was still space when I got on. Waiting for my checked luggage added 30 minutes to my trip. Not the end of the world but also not great.

My seat was assigned last row behind restrooms No legroom’s I’m very Pettit Still was not comfortable Food choice was excellent

There was free WiFi (definitely a plus), but the flight was delayed 45 minutes waiting on a catering truck that never arrived. The pilot said there would be food vouchers given out at the end of the gangway to make up for the inconvenience, but there was no one offering those. Delay made me late for work!

Overall it was a good flight. Because we traveled on a Saturday we were upgraded to FC since my wife and I are both Executive Platinum. The only areas for improvement we noted are better snack assortment and perhaps a little nicer plane as American is flying some older planes now. Everything else on this flight was excellent, which is frankly not the norm for American since we have had multiple issues on prior AA flights.

The smell from the bathroom kept wafting through the cabin. It made people sick.

The seats are too uncomfortable for anyone over 5ft 8in. I'm 5'10" with a back and hip issue and I was in pai for the full duration of the flight.

Delayed an hour due to operational issues. Minimal apologies or care for the significant inconvenience caused. Landed at nearly 1am and they still couldn’t find ground staff to get us off the plane promptly.

Long delays, lack of information about the status of the flight. The flight was delayed 4 times.

Everything you need to know for your flight from Santa Ana to Buffalo

Information on your arrival and departure airports