SNA - BUF

$212 Find Cheap Flights from John Wayne (Santa Ana) to Buffalo - Compare and Save

1 adult
1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$447
Typical prices: $480-$701
American Airlines
Wed 12/12Sun 12/16
SNA - BUF • 1 stop
Cheapest one-way
$212
Typical prices: $230-$354
Multiple Airlines
Sat 12/1
SNA - BUF • 2 stops
Nonstop flights
Not available
There are currently no direct flights between Santa Ana and Buffalo. You'll need to take a connecting flight to reach the destination.
Insights
Insights
When to travel
January
Cheapest • 26% price drop
August
Most popular
Good to know
+1
Good to know
+1
Top layover airports
Charlotte Douglas (CLT)
Cheapest • Avg $451 (round-trip)
Denver Intl (DEN)
Shortest trip • 7h 02m (one-way)
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Insights
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Flight Deals

Cheap Flights from Santa Ana to Buffalo (SNA-BUF)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Santa Ana to Buffalo

Sat, Dec 12 - Wed, Dec 16
American Airlines Logo
8:54 am - 9:49 pmSNA  Santa Ana J. Wayne/Orange Cnty-BUF Buffalo
9h 55m1 stop Chicago O'Hare Intl
American Airlines Logo
7:00 am - 12:30 pmBUF  Buffalo-SNA Santa Ana J. Wayne/Orange Cnty
8h 30m1 stop Dallas/Fort Worth
$447American Airlines
Sat, Dec 12 - Wed, Dec 16
United Airlines Logo
10:20 am - 8:56 pmSNA  Santa Ana J. Wayne/Orange Cnty-BUF Buffalo
7h 36m1 stop Chicago O'Hare Intl
United Airlines Logo
6:30 am - 11:37 amBUF  Buffalo-SNA Santa Ana J. Wayne/Orange Cnty
8h 07m1 stop Chicago O'Hare Intl
$447United Airlines
Fri, Jan 8 - Wed, Jan 13
Delta Logo
12:30 pm - 11:14 pmSNA  Santa Ana J. Wayne/Orange Cnty-BUF Buffalo
7h 44m1 stop Detroit Metropolitan Wayne County
Delta Logo
6:15 am - 10:34 amBUF  Buffalo-SNA Santa Ana J. Wayne/Orange Cnty
7h 19m1 stop Detroit Metropolitan Wayne County
$447Delta
Thu, Jan 7 - Mon, Jan 11
Delta Logo
7:15 am - 5:54 pmSNA  Santa Ana J. Wayne/Orange Cnty-BUF Buffalo
7h 39m1 stop Atlanta Hartsfield-Jackson
Delta Logo
6:05 am - 1:24 pmBUF  Buffalo-SNA Santa Ana J. Wayne/Orange Cnty
10h 19m1 stop Atlanta Hartsfield-Jackson
$447Delta
Wed, Jan 6 - Mon, Jan 11
United Airlines Logo
1:00 pm - 10:53 pmSNA  Santa Ana J. Wayne/Orange Cnty-BUF Buffalo
6h 53m1 stop Denver Intl
United Airlines Logo
5:43 pm - 10:30 pmBUF  Buffalo-SNA Santa Ana J. Wayne/Orange Cnty
7h 47m1 stop Chicago O'Hare Intl
$447United Airlines
Wed, Jan 6 - Mon, Jan 11
American Airlines Logo
8:48 am - 10:56 pmSNA  Santa Ana J. Wayne/Orange Cnty-BUF Buffalo
11h 08m2 stops Chicago O'Hare Intl New York LaGuardia
American Airlines Logo
6:00 am - 10:42 amBUF  Buffalo-SNA Santa Ana J. Wayne/Orange Cnty
7h 42m1 stop Chicago O'Hare Intl
$452American Airlines
Wed, Jan 6 - Mon, Jan 11
United Airlines Logo
10:29 am - 8:51 pmSNA  Santa Ana J. Wayne/Orange Cnty-BUF Buffalo
7h 22m1 stop Chicago O'Hare Intl
United Airlines Logo
10:15 am - 5:09 pmBUF  Buffalo-SNA Santa Ana J. Wayne/Orange Cnty
9h 54m2 stops Chicago O'Hare Intl Denver Intl
$452United Airlines
Sat, Dec 12 - Wed, Dec 16
Southwest Logo
11:10 am - 10:25 pmSNA  Santa Ana J. Wayne/Orange Cnty-BUF Buffalo
8h 15m2 stops Phoenix Sky Harbor Intl Denver Intl
Southwest Logo
2:00 pm - 8:30 pmBUF  Buffalo-SNA Santa Ana J. Wayne/Orange Cnty
9h 30m2 stops Chicago Midway Las Vegas Harry Reid Intl
$457Southwest
Wed, Jan 6 - Mon, Jan 11
Southwest Logo
7:30 pm - 8:25 amSNA  Santa Ana J. Wayne/Orange Cnty-BUF Buffalo
9h 55m2 stops Las Vegas Harry Reid Intl Baltimore/Washington
Southwest Logo
2:05 pm - 8:50 pmBUF  Buffalo-SNA Santa Ana J. Wayne/Orange Cnty
9h 45m2 stops Chicago Midway Las Vegas Harry Reid Intl
$457Southwest
Sat, Dec 26 - Thu, Dec 31
American Airlines Logo
9:51 am - 12:14 amSNA  Santa Ana J. Wayne/Orange Cnty-BUF Buffalo
11h 23m2 stops Phoenix Sky Harbor Intl Charlotte Douglas
American Airlines Logo
7:03 am - 2:04 pmBUF  Buffalo-SNA Santa Ana J. Wayne/Orange Cnty
10h 01m1 stop Dallas/Fort Worth
$572American Airlines
Booking Insights

Price, demand and travel trends for Santa Ana to Buffalo flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

How much is a round-trip flight from Santa Ana to Buffalo?

Round-trip flights from Santa Ana to Buffalo typically range from $480 to $701. The lowest price found in the past 5 days was $447, on American Airlines.

What's the cheapest day of the week to fly from Santa Ana to Buffalo?

Based on deals KAYAK users found in the last 12 months, Wednesday is the cheapest day of the week to fly from Santa Ana to Buffalo. It’s 27% cheaper than the average day, while Thursday is the most expensive, with prices 87% higher.

Find deals

Key details for Santa Ana to Buffalo flights

Low season

February

Cheapest flight

$212
Beat the crowds with an average 85% drop in travelers.
The most popular month to fly with an average 129% increase in travelers.
One-way flight from Santa Ana to Buffalo

When to book flights from Santa Ana to Buffalo

Are your dates flexible? Find out the best times to travel from Santa Ana to Buffalo based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Santa Ana to Buffalo flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines and booking tips.

  • What cabin classes can I book on flights from Santa Ana to Buffalo?

    Two cabin classes are available on flights from Santa Ana to Buffalo:

    • Economy Class
    • First Class

  • How long is a flight from Santa Ana to Buffalo?

    A nonstop flight from Santa Ana to Buffalo takes 00m, covering 2,193 miles.

  • Do I need a passport to fly from Santa Ana to Buffalo?

    No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID or another TSA-accepted form of identification.

  • How much should I expect to pay for a Santa Ana to Buffalo flight?

    Round-trip flights from Santa Ana to Buffalo range from $480 to $701, with an average of $617 over the past 12 months. Anything below $480 counts as a good deal.

  • Have flight prices from Santa Ana to Buffalo changed much recently?

    Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $447 to $2,915. That means the highest observed fare was about 7x higher than the lowest one.

  • How are flight prices from Santa Ana to Buffalo looking right now?

    One-way fares from Santa Ana to Buffalo are currently lower than usual. Average one-way flight prices are about $245, which is 17% below the typical average for this route.

  • What car rental options are available at Buffalo Airport (BUF)?

    Buffalo Airport (BUF) hosts 5 major car rental companies, with daily rates averaging $81 for economy cars. Top options include:

    • Dollar
    • Budget
    • Hertz
    • Thrifty
    • Alamo

  • Which airports can I use when flying from Santa Ana to Buffalo?

    Flights from Santa Ana to Buffalo usually depart from Santa Ana J. Wayne/Orange Cnty (SNA) and arrive at Buffalo (BUF).

  • Which airports do connecting flights from Santa Ana to Buffalo pass through?

    One-stop flights from Santa Ana to Buffalo most commonly connect through:

    • Charlotte Douglas (CLT) - 50% of one-stop connections
    • Chicago O'Hare Intl (ORD) - 29% of one-stop connections
    • Denver Intl (DEN) - 7% of one-stop connections
    • Las Vegas Harry Reid Intl (LAS) - 7% of one-stop connections

  • Can I save money by using flexible dates for flights from Santa Ana to Buffalo?

    Yes. Flexible dates can save you up to 61% on flights from Santa Ana to Buffalo. Wednesday is the cheapest departure day at $456 round-trip on average, while Thursday is the most expensive at $1,156, a difference of $700.

    KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • How much time can I save by choosing a different layover airport from Santa Ana to Buffalo?

    Flying via Denver Intl (DEN) gives the shortest average 1-stop total travel time at 7h 02m, compared with 7h 07m via Phoenix Sky Harbor Intl (PHX) and 7h 12m via Las Vegas Harry Reid Intl (LAS).

  • What is the time difference between Santa Ana and Buffalo?

    Buffalo is 3 hours ahead of Santa Ana (Eastern Time vs Pacific Time). Plan for the time shift when scheduling connections or first-day activities.

Your guide to booking Santa Ana to Buffalo flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates are flexible, aim for a Wednesday departure and avoid flying on Thursday. On this route, Wednesday flights average $456, about $700 less than Thursday fares (61% savings) based on the last 12 months.
  • If you can choose when to travel, plan your Santa Ana to Buffalo trip for January. Fares historically average $456 round-trip in that month - typically $653 less than the most expensive month, which is April (based on the last 12 months).
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to Buffalo Airport.

    • Aloft Buffalo Airport
    • Comfort Inn and Suites Buffalo Airport
    • TownePlace Suites by Marriott Buffalo Airport

More options for your flight from Santa Ana to Buffalo

Complete your trip to Buffalo with a hotel stay or car rental

Car rentals in Buffalo
Hotels in Buffalo
Vacations in Buffalo