$95 Find Cheap Flights from Santa Ana to Iowa

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Santa Ana to Iowa departing on 4/16. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Iowa

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santa Ana to Iowa, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santa Ana to Iowa, as well as popular online travel agencies
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Flight Deals

Cheap Flights from Santa Ana to Iowa

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Des Moines
Des Moinesnonstop$185
Cedar Rapids
Cedar Rapids1 stop$200
Sioux City
Sioux City1 stop$350
Waterloo
Waterloo1 stop$584
Moline
Moline1 stop$309
Des Moines
Des Moinesnonstop$185
Cedar Rapids
Cedar Rapids1 stop$200
Sioux City
Sioux City1 stop$350
Waterloo
Waterloo1 stop$584
Moline
Moline1 stop$309

Book Cheap Santa Ana to Iowa Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Santa Ana to Iowa that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Santa Ana to Iowa

Jumaat, Mac 6 - Isnin, Mac 16
Multiple Airlines Logo
9:45 am - 3:01 pm
SNA
-
DSM
3h 16mnonstop
Multiple Airlines Logo
8:21 pm - 9:53 am
DSM
-
SNA
39h 32m
2 stops
$185Multiple Airlines
Khamis, Feb 26 - Ahad, Mac 1
Frontier Logo
7:25 pm - 6:34 pm
SNA
-
OMA
21h 09m
2 stops
Frontier Logo
1:43 pm - 10:46 am
OMA
-
SNA
23h 03m
1 stop
$197Frontier
Khamis, Feb 26 - Ahad, Mac 1
Multiple Airlines Logo
8:58 am - 11:43 am
SNA
-
OMA
24h 45m
1 stop
Multiple Airlines Logo
1:43 pm - 10:46 am
OMA
-
SNA
23h 03m
1 stop
$200Multiple Airlines
Jumaat, Mac 13 - Sabtu, Mac 21
Multiple Airlines Logo
7:45 am - 12:37 pm
SNA
-
CID
26h 52m
1 stop
Multiple Airlines Logo
10:12 pm - 2:39 pm
CID
-
SNA
18h 27m
1 stop
$200Multiple Airlines
Selasa, Apr 14 - Sabtu, Apr 18
United Airlines Logo
4:15 pm - 11:05 pm
SNA
-
OMA
4h 50m
1 stop
United Airlines Logo
9:05 am - 1:18 pm
OMA
-
SNA
6h 13m
1 stop
$257United Airlines
Selasa, Apr 14 - Sabtu, Apr 18
United Airlines Logo
11:10 am - 9:57 pm
SNA
-
OMA
8h 47m
2 stops
United Airlines Logo
5:22 pm - 8:48 pm
OMA
-
SNA
5h 26m
1 stop
$262United Airlines
Jumaat, Feb 20 - Sabtu, Feb 21
American Airlines Logo
2:53 pm - 10:53 pm
SNA
-
MLI
6h 00m
1 stop
American Airlines Logo
2:02 pm - 9:39 pm
MLI
-
SNA
9h 37m
1 stop
$309American Airlines
Jumaat, Feb 20 - Sabtu, Feb 21
American Airlines Logo
12:26 pm - 11:37 pm
SNA
-
MLI
9h 11m
2 stops
American Airlines Logo
2:02 pm - 9:39 pm
MLI
-
SNA
9h 37m
1 stop
$314American Airlines
Jumaat, Mac 6 - Jumaat, Mac 13
Allegiant Air Logo
9:45 am - 3:01 pm
SNA
-
DSM
3h 16mnonstop
Allegiant Air Logo
7:00 am - 8:55 am
DSM
-
SNA
3h 55mnonstop
$334Allegiant Air
Rabu, Apr 15 - Sabtu, Apr 18
Delta Logo
11:55 am - 10:35 pm
SNA
-
MLI
8h 40m
1 stop
Delta Logo
5:55 am - 11:59 am
MLI
-
SNA
8h 04m
1 stop
$359Delta
Booking Insights

KAYAK's insights & trends for Santa Ana to Iowa flights

Get data-powered insights and trends into flights from Santa Ana to Iowa to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest Santa Ana to Iowa flight route?

Data is based on round-trip flight searches on KAYAK over the past month.

The cheapest ticket to Iowa from Santa Ana found in the last 72 hours was to Des Moines, at $73 round-trip. The most popular route is from Santa Ana (SNA) to Des Moines (DSM), and the cheapest round-trip airline ticket found on this route in the last 72 hours was $73.

Can I save money by flying with a layover from Santa Ana to Iowa?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

No, with an average price for the route of $196, prices are generally cheapest when you fly direct.

What is the cheapest month to fly from Santa Ana to Iowa?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Santa Ana to Iowa, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Santa Ana to Iowa is January, when tickets cost $176 (return) on average. On the other hand, the most expensive months are July and June, when the average cost of round-trip tickets is $441 and $436 respectively.

What’s the cheapest day of the week to fly from John Wayne (Santa Ana) to Iowa?

The average price of all round-trip flights from Santa Ana to Iowa clicked on KAYAK for each day over the last 12 months.

If you are looking for a flight deal from John Wayne (Santa Ana) to Iowa, look for departures on Mondays and avoid leaving on a Tuesday, as it's usually the priciest day. When flying back from Iowa, Wednesday is the cheapest day to fly and Tuesday is the most expensive.

Good to know

Low seasonDecember
Cheapest flight$95
Best time to beat the crowds with an average 4% drop in price.
Most popular time to fly and prices are also 6% lower on average.
Flight from John Wayne (Santa Ana) to Omaha

FAQs - booking Iowa flights

  • How does KAYAK find such low prices on flights from John Wayne (Santa Ana) to Iowa?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from John Wayne (Santa Ana) to Iowa.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from John Wayne (Santa Ana) to Iowa?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from John Wayne (Santa Ana) to Iowa is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from John Wayne (Santa Ana) to Iowa?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from John Wayne (Santa Ana) to Iowa with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from John Wayne (Santa Ana) to Iowa?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from John Wayne (Santa Ana) to Iowa up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to Iowa?

    The cheapest time of day to fly to Iowa is generally in the morning, when round-trip flights cost $186 on average. The most expensive time of day to fly to Iowa is generally in the morning, which is peak travel time and where the average cost of a ticket is $186.

Reviews of the top 5 airlines serving from Santa Ana to Iowa

 
See real verified KAYAK customer reviews for airlines flying from Santa Ana to Iowa. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Santa Ana to Iowa? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
SouthwestOverall score based on 4267 reviews
8.6Crew
8.1Boarding
7.0Food
8.0Comfort
7.5Entertainment
Airline reviews

Great flight but super high price. Glad it was a business trip and not personal

10.0 ExcellentPieter, Jan 2026
LGB - DAL
Read more Southwest reviews

Great flight but super high price. Glad it was a business trip and not personal

3 hour delay. Had to change plans and was still delayed.

We got exit row seats both flights. Everything was running on time

The boarding and seat assignment system no longer works for me, but I know it is being replaced. Otherwise, I am good with the overall experience.

The lead steward kept singing about "San Francisco" and hotel California---more annoying than humorous....needs work. Flight was smooth and on time.

San Diego airport is brand new, spacious, airy and very smooth checkin at SW baggage drop.

Crew could have been friendlier, maybe I'm spoiled by SW crews. In flight wifi was good. Would be nice to have more food offerings on a 4 plus hour flight

Ever since Southwest starting charging for bags, passengers don't want to pay to check their bags, so the gate agents have to beg people to check their roller bags now because there's "not enough space". This was a terrible business move by Southwest.

Sacrament staff are always polite and helpful. Airport is easy to maneuver and boarding is straightforward.

As always, the entire Southwest experience was wonderful, from online booking to flight to baggage retrieval. Very grateful.

Delta One is extraordinary. I fly business when somebody hires me. I just wonder why there is such a chasm between business class and the insanely inhumane and nonsensical coach. The seats are not large enough to fit even my tiny wife. We fly 10% of what we did because we don’t want to pay 5-10 k but for $400 it’s unbearable. It seems like the accountants took over and made stupid decisions. Screw in 20 extra seats and make it so unbearable that people fly 90% less. Just put the damn price up and put some proper chairs in. But business, yay.

Delta’s staff is unmatched. From the gate agents, to the pilots, to the flight attendants… all top of the industry.

The flight was delayed for about 2 hrs. Other than it, it was good.

I am extremely disappointed that delta internal pilot manuals now refer to the Gulf of Mexico as the “gulf of America”. You can bow down to the Orange turd on your own. I will never fly delta again

No lunch on a x-country flight scheduled for 10:50 am departure, arrived 5+ hrs later. That requires a black box label before you pay for the tickets. Worst, when I checked in online, it's specifically said that lunch was served on his flight for economy Plus passengers.

Our flight from SFO to MSP was right on time on 11/15/2025. No delays. As we approached MSP at about 8 pm, we circled in the air until 8:40 pm so I don't call that efficient for MSP. I think the captain should announce the delay and why. (as if we all don't know that we are just circling around the area, slowing down, speeding up, slowing down.) Thank you. Marilyn Fischer

Staff were friendly and happy. Delta could make sure passengers that don't have the app know of changes. Without Kayak I would not have known about the change of gate or the delay. Kayak was faster to notify me.

The flight used a B767 with a very old interior from before 2014. The entertainment system did not work at all during the flight despite attempts to reset the system. It was like they flew this route just to be competitive.

Delayed flight (1hour) plus a long layover after an overnight flight with no backup plane available.

Flight delayed for two and half hours and then canceled altogether due to mechanical issues. No mechanic onsite to fix so had to send one from LAX.

It was a pretty standard flight... until the almost hour and a half spent on the taxi way. I get that the weather has been poor but the delay had nothing to do with the weather and more to do with a plane with several issues tying up the gate. I get that that happens from time to time but this has been EVERY flight I've been on for the past 5 years and I fly 3 to 5 times a year. This isn't just United... it's American, it's Delta. It's an issue with the entire industry. I work for UPS and packages on a cargo plane get better service than people do these days. Anymore I HATE flying.

The flight crew where really good. Better then the crew from BNE to SFO

left on time, reasonable boarding process arrived early luggage came out quickly

I’m so sorry, I can’t remember her name, I believe it was Dimpti. She was stellar, also a mature Asian flight attendant, lots of flowers in her hair, just as amazing! But literally the crew was AWESOME . Only downside is there weren’t any charging outlets. Maybe I needed to ask a flight attendant , but it would’ve been nice to have one easily accessible.

I boarded flight UA#1318 at Sacramento International Airport going back to Houston TX. The flight was scheduled at 5:10am. I was able to check in virtually using the United Airlines app. When I entered the airport, there was no one outside assisting with checked bags as it was for Delta Airlines. Immediately upon entering, there was a LONG, EXTREMELY LONG line to the kiosks to get boarding passes. I stand in line to get boarding passes then had to move to ANOTHER EXTREMELY LONG line to get my bags checked in. While standing in this line, we noticed an agent taking customers to 3 at a time to her station to check their bags in. Lucky for me, she called me back, checked my bags for me and I was on my way. I then encountered another long line at the TSA check and to avoid I ending up having to sign up for CLEAR to bypass it. So glad, I did.,...Both of my flights were great with no issues, butthe check in progress at Bush Airport was so much smoother. Check-in at SMF airport needs to be anaylzed and corrected. Do better United, I know you can....thanks

Pushed back only to get deplaned due to a tire damaged by ground crew. They did at least go pretty fast. The bathrooms should be banned under the Geneva convention. No room to even sit straight on the toilet. The under-seat entertainment units block what little leg room there is.

United airlines has the best customer experience from booking to arrival. I always fly United airlines. The mileage program is excellent

Older aircraft, no meal, only food was for purchase. Not impressed United.

Not pleasant trip cross country when the entertainment and WiFi system not working. No entertainment for entirety of route. Staff was rather nonchalant in that they dismissed the problem due to age of plane. It would have been nice to know this up front so I could have come prepared to read or download movies before boarding Coincidentally or not, there was a similar issue with the entertainment system on my previous flight I took on my fist leg of the trip. There are no seat TVs, so you must rely on the app when it works. United can do better. Also, what use it it to pay for boarding group 2 when half of the passengers are in the same line as you?

Premium Plus is a really good idea for longer flights

It would be nice to have some low carb options in the snacks.

The entertainment options were at best, fair. It was exactly the same as my outbound flight. It would have been more entertaining if there were some series from Apple TV, HBO, Showtime or other carriers for me to catch up with.

The flight was on time and arrived early. The crew were friendly and helpful.

Overall experience was great. Flights were almost on time in departing and we arrived at our destination as scheduled. No issues with amenities or flight crew. Everything went well as as expected. Will fly again with American Airlines in the future!

The boarding by groups is pointless. The first two groups worked fine, but almost Noone boarded in goups three thru five leaving the vast majority boarding when group six was called. It defeated the purpose of spreading out the crowd.

Horrible. Both legs of my flight were delayed more than 6 hours. No compensation, no screens on the plane, and the plane was not clean.

The flight was smooth, the pilot kept us informed about delays and we arrived more of less on time

The flight was flawless and we even arrived between 20 and 25 minutes early!

Always seated jammed in rear of aircraft Admirals Club food at DFW terminal D was absolute worst food experience and I pay $600/year to eat this dried out junk

Mostly good. Flight was crowded but Airline personnel were very friendly & accommodating. It would be good to have savory snacks rather than just sweet Biscoff cookies.

It was fine. Nobody was outstandingly friendly but no one was rude and everything was smooth . The captain thanked us for flying but no one greeted me as I walked on the plane or as I exited which is the least they could do lol

Clean, friendly, roomy. But check-in from the phone link was terrible. Repeated attempts wouldn’t save at the final step. Just kept spinning! It was very frustrating. Finally, I used the app (vs website link) to check-in which worked very smoothly on the first attempt.

Check in on the web portal was cumbersome! After several attempts I finally got the boarding pass.

Excellent flight and even arrived 23 min early. No entertainment , or wi fi on board, but I downloaded a couple of movies beforehand which kept me entertained. Really like flying Allegiant airlines.

WE were delayed about an hour and never any communications from the employees working the gate. We also were moved to a total of three gates.

I love how they show love to their customers and care about them too.

I liked how when I got on board how fast we ended up taking off but what I truly disliked was how uncomfortable the seats were. There was truly never a time that I could ever get comfortable during both of my flights. The seats could get away during shorter flights but flights 3 hour plus makes it hard to enjoy.

The crew was great and the flight was very smooth. Can’t really judge food since I did not get any because it costs money. The seat was comfortable for what we bought. Thanks!

Crew was great. No entertainment and food and beverage was for purchase only, even water

It was canceled. The flight wasn’t rescheduled, everyone had to figure out their own new arrangements. They said we would get refunded our original fare and receive an additional $150. We received links for $100 only and they expired before we could activate them.

Everything you need to know for your flight from Santa Ana to Iowa

Information on your arrival and departure airports