$120 Find Cheap Flights from John Wayne (Santa Ana) to Iowa

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Santa Ana to Iowa departing on 5/20. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Iowa

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from John Wayne (Santa Ana) to Iowa, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from John Wayne (Santa Ana) to Iowa, as well as popular online travel agencies
Travelers love KAYAK
41,299,237 searches in the past 7 days on KAYAK

Save 24% or moreCompare multiple travel sites with one search.

Track pricesNot ready to book? Create a price alert for when prices drop.

Bundle and saveSave money when you bundle your flight + hotel.

Filter your dealsChoose cabin class, free Wi-Fi and more.

Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Santa Ana to Iowa

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Des Moines
Des Moinesnonstop$163
Cedar Rapids
Cedar Rapids1 stop$309
Sioux City
Sioux City1 stop$404
Moline
Moline1 stop$302
Des Moines
Des Moinesnonstop$163
Cedar Rapids
Cedar Rapids1 stop$309
Sioux City
Sioux City1 stop$404
Moline
Moline1 stop$302

Book Cheap Santa Ana to Iowa Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Santa Ana to Iowa that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Santa Ana to Iowa

Thu, May 21 - Sun, May 24
Allegiant Air Logo
10:32 am - 3:51 pm
SNA
-
DSM
3h 19mnonstop
Allegiant Air Logo
8:00 am - 9:42 am
DSM
-
SNA
3h 42mnonstop
$163Allegiant Air
Thu, May 21 - Sun, May 24
Allegiant Air Logo
10:32 am - 3:51 pm
SNA
-
DSM
3h 19mnonstop
Allegiant Air Logo
8:00 am - 9:42 am
DSM
-
SNA
3h 42mnonstop
$180Allegiant Air
Tue, May 19 - Wed, May 27
Multiple Airlines Logo
7:30 am - 12:59 pm
SNA
-
DSM
27h 29m
1 stop
Multiple Airlines Logo
2:16 pm - 9:09 am
DSM
-
SNA
20h 53m
1 stop
$198Multiple Airlines
Thu, Aug 20 - Sun, Aug 23
Multiple Airlines Logo
8:10 pm - 6:48 pm
SNA
-
DSM
20h 38m
1 stop
Multiple Airlines Logo
10:00 am - 11:36 am
DSM
-
SNA
3h 36mnonstop
$213Multiple Airlines
Thu, May 28 - Sun, May 31
Frontier Logo
9:54 am - 7:34 pm
SNA
-
OMA
7h 40m
1 stop
Frontier Logo
8:19 pm - 9:09 am
OMA
-
SNA
14h 50m
1 stop
$261Frontier
Thu, May 28 - Sun, May 31
Frontier Logo
9:54 am - 7:34 pm
SNA
-
OMA
7h 40m
1 stop
Frontier Logo
8:19 pm - 9:09 am
OMA
-
SNA
14h 50m
1 stop
$281Frontier
Sat, May 23 - Sat, Aug 22
American Airlines Logo
3:08 pm - 11:30 pm
SNA
-
CID
6h 22m
1 stop
American Airlines Logo
5:00 am - 10:31 am
CID
-
SNA
7h 31m
1 stop
$331American Airlines
Sat, May 23 - Sat, Aug 22
American Airlines Logo
1:01 pm - 11:41 pm
SNA
-
CID
8h 40m
1 stop
American Airlines Logo
7:44 am - 12:30 pm
CID
-
SNA
6h 46m
1 stop
$341American Airlines
Sat, Aug 29 - Tue, Sep 1
United Airlines Logo
4:00 pm - 11:46 pm
SNA
-
SUX
5h 46m
1 stop
United Airlines Logo
11:32 am - 3:04 pm
SUX
-
SNA
5h 32m
1 stop
$404United Airlines
Sat, Aug 29 - Tue, Sep 1
United Airlines Logo
4:00 pm - 11:46 pm
SNA
-
SUX
5h 46m
1 stop
United Airlines Logo
11:32 am - 8:51 pm
SUX
-
SNA
11h 19m
2 stops
$414United Airlines
Booking Insights

KAYAK's insights & trends for Santa Ana to Iowa flights

Get data-powered insights and trends into flights from Santa Ana to Iowa to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Santa Ana, California to Iowa?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Santa Ana, California to Iowa departing in May.

What is the cheapest John Wayne (Santa Ana) to Iowa flight route?

Data is based on round-trip flight searches on KAYAK over the past month.

The cheapest ticket to Iowa from John Wayne (Santa Ana) found in the last 72 hours was to Des Moines, at $155 round-trip. The most popular route is from John Wayne (Santa Ana) (SNA) to Des Moines (DSM), and the cheapest round-trip airline ticket found on this route in the last 72 hours was $155.

What is the cheapest time of day to fly to Iowa?

The average price for all round-trip flights from Santa Ana to Iowa depending on the time of departure, clicked by users on KAYAK in the last 2 weeks.

The cheapest time of day to fly to Iowa is generally in the morning, when round-trip flights cost $195 on average. The most expensive time of day to fly to Iowa is generally in the morning, which is peak travel time and where the average cost of a ticket is $195.

Can I save money by flying with a layover from John Wayne (Santa Ana) to Iowa?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

No, with an average price for the route of $238, prices are generally cheapest when you fly direct.

What is the cheapest month to fly from John Wayne (Santa Ana) to Iowa?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Santa Ana to Iowa, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from John Wayne (Santa Ana) to Iowa is August, when tickets cost $72 (return) on average. On the other hand, the most expensive months are March and July, when the average cost of round-trip tickets is $309 and $201 respectively.

What’s the cheapest day of the week to fly from John Wayne (Santa Ana) to Iowa?

The average price of all round-trip flights from Santa Ana to Iowa clicked on KAYAK for each day over the last 12 months.

If you are looking for a flight deal from John Wayne (Santa Ana) to Iowa, look for departures on Mondays and avoid leaving on a Tuesday, as it's usually the priciest day. When flying back from Iowa, Sunday is the cheapest day to fly and Tuesday is the most expensive.

Good to know

Low seasonMarch
Cheapest flight$120
Best time to beat the crowds with an average 16% drop in price.
Most popular time to fly and prices are also 2% lower on average.
Flight from John Wayne (Santa Ana) to Des Moines

FAQs - booking Iowa flights

  • How does KAYAK find such low prices on flights from John Wayne (Santa Ana) to Iowa?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from John Wayne (Santa Ana) to Iowa.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from John Wayne (Santa Ana) to Iowa?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from John Wayne (Santa Ana) to Iowa is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from John Wayne (Santa Ana) to Iowa?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from John Wayne (Santa Ana) to Iowa with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from John Wayne (Santa Ana) to Iowa?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from John Wayne (Santa Ana) to Iowa up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 3 airlines serving from Santa Ana to Iowa

 
See real verified KAYAK customer reviews for airlines flying from John Wayne (Santa Ana) to Iowa. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Santa Ana to Iowa? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
United AirlinesOverall score based on 9677 reviews
7.1Entertainment
7.3Comfort
7.7Boarding
8.1Crew
6.6Food
Airline reviews

Booked through Kayak Business, had a seat in middle and towards back due to booking rate, not comfortable.

4.0 OkayMichael, Apr 2026
SNA - DEN
Read more United Airlines reviews

Booked through Kayak Business, had a seat in middle and towards back due to booking rate, not comfortable.

A long delay. Don't travel late in the day.

Outstanding service, efficient & friendly crew, flight was safe, comfortable & on time

The seat was comfortable. There was a lot of turbulence. If it weren't for that,it would have been okay.

It was a red-eye, but the flight felt surprisingly quick. The seats were very comfortable, and that made resting much easier. I also want to thank the gentleman seated next to me, who graciously moved so my mom could sit beside me. We slept almost the entire way. The cabin crew was respectful in not disturbing us, while also being courteous and professional throughout. Thank you, United.

Boarding was again a "free for all". We were boarding group 4, and almost the entire plane was able to board before us. It's a shame that someone who follows the rules, gets the short end of the stick. Not fair.

It was perfect! I've never flown with United before, but I definitely will in the future

I had a cancelled flight because of technical issues going to my destination, and a delayed flight coming home. All told it wasn’t a total bust.

They delayed the flight from 9:00 to 11:55 At 11:45 they canceled the flight. I paid a premium price for the tickets with poor service

My flight was canceled a few hours before boarding. I was rebooked on Copa airlines and missed an important meeting .

Great. No choice for n/a. No food or entertainment options

No food is available without purchasing it and there is no in-flight entertainment. Both of these are OK because we got an inexpensive flight from Allegiant and, otherwise, our experience was excellent.

just had water and there was plenty of leg & seat room. But then i don't weight 220#s!!

Not totally their fault- screaming kids that had zero parent intervention.

It was cold on the flight. The crew was very pleasant. I didn't order any food. We were delayed due to Captain waiting on maintenance log. He kept us informed though. The flight itself was smooth. I would definitely fly with Allegiant again!

I had a fantastic experience with Allegiant. I had wheelchair assistance and they helped me find my luggage and brought me to my car. Even loaded my luggage. Wonderful service!! Thank you Allegiant!

Superb. Staff great. Great flight. As with other airlines, seating too tight and restrictive.

There is not one likable thing about this airline. It’s starts with the deceptive pricing and continues through the whole flight. The worst staff I’ve ever experienced way over priced bags absolutely no food or drink (unacceptable and you should be embarrassed) the seats are cramped and uncomfortable there is no entertainment there is nothing about this trash airline that constitutes any amount of money. It’s worse than spirit and way more expensive it is disgraceful. Do not travel with Allegiant I repeat do not bother no matter what they say the price is it is never ever going to be the right choice I’m mind blown at how awful the entire experience was I’m embarrassed that I chose so poorly I cannot reiterate enough how beyond horrible this company and its staff are, not one person on this flight or at the airport is qualified to sweep up trash on a city sidewalk they should certainly never be given any job that requires a brain or manners or communication with human beings, what a disgrace to the human race. Your criminal chiselers and should be put out to pasture

Great flight. Friendly staff. Free snacks and drinks would be nice. I would love fewer taxes and fees added on.

My 90 year old father flew with me. He needed wheel chair assistance and is nearly deaf. The staff was amazing with him.

Left early arrived early..right amount of talking from pilots..of course had to love the biscuit and water!

Boarding gate at LAX was too crowded—two gates next to one another

On time departure and early arrival. Flight attendant very nice.

The SFO Lounge crew were amazing. The bartender Faris was great. Thanks!

Was not able to do a online check-in because the American Airlines system doesn't store our visa or other passport information, allowing us to have a trouble-free check-in. We were forced to have to check-in at the counter which Changes are upgrade status given that we were not able to check in much earlier.

Good flight, seated and had a water within 5 minutes. Crew was hospitable.

We left at 1030 am pacific from LA and supposed to land at 7 pm Eastern in NY. They made a detour, stopped in Philadelphia and didn’t land till 1130 PM Eastern!!! Worst flight experience with no pilot communication with no explanation as to what was going on. Everyone was very frustrated to say the least.

Flight boarded from Gate 159B, the farthest gate in the LAX Bradley Terminal. While the flight operated on time, the first class cabin attendant made no recognition of my being an Advantage Executive Platinum member.

The flight itself was excellent but the gate attendant made me check my carryon since she said it was an inch too big. I’ve had no problems with this carryon on recent flights on Qantas, Delta, Austrian, Southwest Airlines even though the overhead bins are the same size. there were other carryons in the bins that also looked larger than mine and there was room left in the bins for more. When I picked up my carryon from baggage claim one of the wheels had broken off.

I was in last row so that is never great bc the person in front of me leaned his seat all the way back into me.

Everything you need to know for your flight from Santa Ana to Iowa

Information on your arrival and departure airports