$69 Find Cheap Flights from John Wayne (Santa Ana) to Iowa - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Santa Ana to Iowa departing on 8/27. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Iowa

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from John Wayne (Santa Ana) to Iowa, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from John Wayne (Santa Ana) to Iowa, as well as popular online travel agencies
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Flight Deals

Cheap Flights from Santa Ana to Iowa

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Des Moines
Des Moinesnonstop$156
Cedar Rapids
Cedar Rapids1 stop$340
Sioux City
Sioux City1 stop$401
Waterloo
Waterloo1 stop$641
Moline
Moline1 stop$349
Des Moines
Des Moinesnonstop$156
Cedar Rapids
Cedar Rapids1 stop$340
Sioux City
Sioux City1 stop$401
Waterloo
Waterloo1 stop$641
Moline
Moline1 stop$349

Book Cheap Santa Ana to Iowa Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Santa Ana to Iowa that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Santa Ana to Iowa

Sun, Aug 9 - Sun, Aug 16
Allegiant Air Logo
9:32 am - 2:51 pm
SNA
-
DSM
3h 19mnonstop
Allegiant Air Logo
7:00 am - 8:42 am
DSM
-
SNA
3h 42mnonstop
$156Allegiant Air
Sun, Aug 9 - Sun, Aug 16
Allegiant Air Logo
9:32 am - 2:51 pm
SNA
-
DSM
3h 19mnonstop
Allegiant Air Logo
7:00 am - 8:42 am
DSM
-
SNA
3h 42mnonstop
$172Allegiant Air
Thu, Oct 22 - Sun, Oct 25
Multiple Airlines Logo
3:07 pm - 12:37 pm
SNA
-
DSM
19h 30m
1 stop
Multiple Airlines Logo
2:18 pm - 3:56 pm
DSM
-
SNA
3h 38mnonstop
$217Multiple Airlines
Fri, Oct 23 - Mon, Oct 26
Multiple Airlines Logo
7:30 am - 9:31 pm
SNA
-
OMA
12h 01m
1 stop
Multiple Airlines Logo
9:56 pm - 3:03 pm
OMA
-
SNA
19h 07m
1 stop
$262Multiple Airlines
Wed, Oct 21 - Wed, Oct 28
Delta Logo
7:00 am - 5:11 pm
SNA
-
OMA
8h 11m
1 stop
Delta Logo
12:27 pm - 4:17 pm
OMA
-
SNA
5h 50m
1 stop
$263Delta
Thu, Aug 20 - Tue, Aug 25
Delta Logo
7:00 am - 4:49 pm
SNA
-
OMA
7h 49m
1 stop
Delta Logo
12:42 pm - 6:22 pm
OMA
-
SNA
7h 40m
1 stop
$291Delta
Thu, Aug 20 - Tue, Aug 25
United Airlines Logo
8:55 am - 4:28 pm
SNA
-
OMA
5h 33m
1 stop
United Airlines Logo
1:55 pm - 8:51 pm
OMA
-
SNA
8h 56m
2 stops
$296United Airlines
Thu, Sep 10 - Tue, Sep 15
American Airlines Logo
1:40 pm - 11:18 pm
SNA
-
CID
7h 38m
1 stop
American Airlines Logo
5:00 am - 9:45 am
CID
-
SNA
6h 45m
1 stop
$340American Airlines
Mon, Aug 17 - Sat, Aug 22
American Airlines Logo
3:21 pm - 12:08 am
SNA
-
MLI
6h 47m
1 stop
American Airlines Logo
6:00 am - 10:30 am
MLI
-
SNA
6h 30m
1 stop
$349American Airlines
Fri, Jul 10 - Thu, Jul 16
United Airlines Logo
10:20 am - 8:39 pm
SNA
-
CID
8h 19m
1 stop
United Airlines Logo
5:30 am - 9:07 am
CID
-
SNA
5h 37m
1 stop
$349United Airlines
Booking Insights

KAYAK's insights & trends for Santa Ana to Iowa flights

Get data-powered insights and trends into flights from Santa Ana to Iowa to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Santa Ana, California to Iowa?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Santa Ana, California to Iowa departing in August.

What is the cheapest John Wayne (Santa Ana) to Iowa flight route?

Data is based on round-trip flight searches on KAYAK over the past month.

The cheapest ticket to Iowa from John Wayne (Santa Ana) found in the last 5 days was to Des Moines, at $182 round-trip. The most popular route is from John Wayne (Santa Ana) (SNA) to Des Moines (DSM), and the cheapest round-trip airline ticket found on this route in the last 5 days was $182.

What is the cheapest time of day to fly to Iowa?

The average price for all round-trip flights from Santa Ana to Iowa depending on the time of departure, clicked by users on KAYAK in the last 2 weeks.

The cheapest time of day to fly to Iowa is generally in the morning, when round-trip flights cost $198 on average. The most expensive time of day to fly to Iowa is generally in the morning, which is peak travel time and where the average cost of a ticket is $198.

Can I save money by flying with a layover from John Wayne (Santa Ana) to Iowa?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

No, with an average price for the route of $222, prices are generally cheapest when you fly direct.

What is the cheapest month to fly from John Wayne (Santa Ana) to Iowa?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Santa Ana to Iowa, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from John Wayne (Santa Ana) to Iowa is August, when tickets cost $72 (return) on average. On the other hand, the most expensive months are March and June, when the average cost of round-trip tickets is $309 and $196 respectively.

What’s the cheapest day of the week to fly from John Wayne (Santa Ana) to Iowa?

The average price of all round-trip flights from Santa Ana to Iowa clicked on KAYAK for each day over the last 12 months.

If you are looking for a flight deal from John Wayne (Santa Ana) to Iowa, look for departures on Mondays and avoid leaving on a Tuesday, as it's usually the priciest day. When flying back from Iowa, Sunday is the cheapest day to fly and Tuesday is the most expensive.

Good to know

Low seasonMarch
Cheapest flight$69
Best time to beat the crowds with an average 14% drop in price.
Most popular time to fly with an average 20% increase in price.
Flight from John Wayne (Santa Ana) to Des Moines

FAQs - booking Iowa flights

  • How does KAYAK find such low prices on flights from John Wayne (Santa Ana) to Iowa?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from John Wayne (Santa Ana) to Iowa.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from John Wayne (Santa Ana) to Iowa?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from John Wayne (Santa Ana) to Iowa is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from John Wayne (Santa Ana) to Iowa?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from John Wayne (Santa Ana) to Iowa with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from John Wayne (Santa Ana) to Iowa?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from John Wayne (Santa Ana) to Iowa up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 3 airlines serving from Santa Ana to Iowa

 
See real verified KAYAK customer reviews for airlines flying from John Wayne (Santa Ana) to Iowa. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Santa Ana to Iowa? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
United AirlinesOverall score based on 9828 reviews
7.3Comfort
6.6Food
7.1Entertainment
8.1Crew
7.7Boarding
Airline reviews

Service was professional and quick. Premium economy seat was comfortable given the class

10.0 ExcellentDavid, Jun 2026
SAN - LAX
Read more United Airlines reviews

Service was professional and quick. Premium economy seat was comfortable given the class

The staff was extremely helpful and friendly at all times! They went above and beyond to get us into an earlier flight in San Diego to make our connection in SFO possible, because our original flight did actually not make it! I did so much appreciate the UA team and how they made this possible. We also didn’t have seats together on the long flight to Singapore, but they found us seats together last moment with no additional cost! Nobody sat next to us, so that we were able to sleep! Thanks to UA for improving their service and Underpricer for booking this trip! Please be careful: 1,5 hrs for transfer in San Francisco might not be enough time in the future

Over 2.5 hour maintenance delay on first morning flight with no acknowledgement, compensation or even gesture of good will. Aircraft had overnighted at airport so issue should have been addressed prior to boarding. Over 3.5 hours before first slow and deliberate beverage service.

Horrifying Almost 2 million miles. Bring your own food and drink. One coffee or drink every three hours. Have to order meals on app more than 24 hours ahead Tiny and dirty bathrooms

Flight was delayed but more than 90 minutes. This caused me to miss my available windows for pick-up by a friend. I had to pay $125 for an uber back home from the airport which was an added expense that I had not budgeted for my trip. Staff was friendly.

Seat pitch is horrible especially on the 15 hour flight. Gate crew at SFO was Outstanding. The flight crew was also great.

My service dog and I were asked to deplane just before they closed the door - clearly very last minute they couldn’t find the documentation that I have filled out many many times before that is for flying service animals. I purposely purchase 3seats (a whole row) since he is large and not all passengers want to sit next to a dog on a cross country flight. The plane departed with my husband on it!!! They made me fill out a hard copy of the same form and had to reschedule me on a later flight where they could find 3 seats together!! I’ve done this so many times before - clearly the error was on their part in a technology glitch - but really people - do better!! Very traumatic - and my husband had to wait for us when he landed ….so bad. Poor pup was confused and tired.

Late plane. Only one crew on the ground so we b had to wait for Denver flight to come in, board, and depart. At 78 yrs of age I was not pleased trying to get my connection. What really made me angry was the notification you sent me to hurry up or I would miss my connection. Why tell me to hurry up when you got me in late. It was not a good way of treating customers.

No screens or meal options. Freezing cold. Dirty seats. Left late.

Booked through Kayak Business, had a seat in middle and towards back due to booking rate, not comfortable.

Seats were very uncomfortable and being charged for snacks and water.........

Allegiant actually impressed me, original inbound flight from PBG was so late they gave us a bird inbound from Des Moines and only left 1h late and gained 40 minutes back in the air. Comfortable flight with no frills but no complaints.

Flight was delayed. Crew was good but hot coffee was not available.

Great. No choice for n/a. No food or entertainment options

No food is available without purchasing it and there is no in-flight entertainment. Both of these are OK because we got an inexpensive flight from Allegiant and, otherwise, our experience was excellent.

just had water and there was plenty of leg & seat room. But then i don't weight 220#s!!

Not totally their fault- screaming kids that had zero parent intervention.

It was cold on the flight. The crew was very pleasant. I didn't order any food. We were delayed due to Captain waiting on maintenance log. He kept us informed though. The flight itself was smooth. I would definitely fly with Allegiant again!

I had a fantastic experience with Allegiant. I had wheelchair assistance and they helped me find my luggage and brought me to my car. Even loaded my luggage. Wonderful service!! Thank you Allegiant!

Superb. Staff great. Great flight. As with other airlines, seating too tight and restrictive.

The gate experience at LAX was abysmal (same for the arrival experience two days prior). Despite the LAX -> SAT schedule of two flights daily, our departure gate was at a smaller hub that we had to be bussed to from Terminal 4. Fortunately, I arrived at LAX extra early and had time to spare, but if I had not known, I might have missed my flight. I looked at the LAX airport map in the AA app and there was no indication of the additional boarding process. Lastly the gate area we were bussed to was crowded with limited food and beverage options. On flight, the fight attendant was hospitable and attentive, the flight was smooth, and AA's free (and working) wifi for AA members were all on the positive side.

Our flight from JFK to Madrid was delayed. We had to go from one side of the Madrid airport (Terminal 4s to the far end of terminal 4 - Gate K98) to our gate in less than 30 minutes. Put passport control and security/baggage check and that’s very hard unless you’re Usain Bolt. I called Iberia Airlines and the telephone customer service told me that I was going to have to pay to re-book. Luckily the help desk in the airport (who was dealing with dozens of people from the same JFK-Madrid flight) did not charge us extra to reschedule to a flight 8 hours later. They also gave us a voucher for breakfast and lunch. Glad the actual person at the airport had some actual sense.

Take-off delayed an hour because of a missing flight officer, so,arrived in Charlotte lates causing many passengers to miss connections. Otherwise a very good flight, safe and comfortable, with an excellent professional crew.

The flight from LA to Chicago was smooth and service was very good overall.

Ontario airport boarding was very easy to park and access, is clean and TSA took 10 minutes total. Check-in was a breeze and cruise was very nice.

Left early arrived early..right amount of talking from pilots..of course had to love the biscuit and water!

Boarding gate at LAX was too crowded—two gates next to one another

On time departure and early arrival. Flight attendant very nice.

The SFO Lounge crew were amazing. The bartender Faris was great. Thanks!

Was not able to do a online check-in because the American Airlines system doesn't store our visa or other passport information, allowing us to have a trouble-free check-in. We were forced to have to check-in at the counter which Changes are upgrade status given that we were not able to check in much earlier.

Everything you need to know for your flight from Santa Ana to Iowa

Information on your arrival and departure airports