$256 Find Cheap Flights from South America to Detroit

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight to Detroit departing on 6/10. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Flight Deals

Cheap Flights from South America to Detroit

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from South America to Detroit that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from South America to Detroit

Thu, Aug 6 - Sun, Aug 16
JetBlue Logo
2:25 pm - 3:10 pm
MDE
-
DTW
23h 45m
1 stop
JetBlue Logo
6:00 am - 2:45 pm
DTW
-
MDE
9h 45m
1 stop
$537JetBlue
Wed, Jul 8 - Wed, Aug 12
JetBlue Logo
12:20 pm - 3:10 pm
MDE
-
DTW
25h 50m
1 stop
JetBlue Logo
6:00 am - 2:45 pm
DTW
-
MDE
9h 45m
1 stop
$552JetBlue
Fri, Jul 17 - Sat, Aug 22
JetBlue Logo
1:30 pm - 3:10 pm
MDE
-
DTW
24h 40m
1 stop
JetBlue Logo
6:00 am - 2:45 pm
DTW
-
MDE
9h 45m
1 stop
$557JetBlue
Wed, Sep 9 - Wed, Sep 16
Multiple Airlines Logo
4:25 am - 10:20 pm
BOG
-
DTW
16h 55m
2 stops
Multiple Airlines Logo
6:55 pm - 1:55 pm
DTW
-
BOG
20h 00m
1 stop
$611Multiple Airlines
Thu, Jul 16 - Mon, Jul 27
American Airlines Logo
12:20 pm - 11:56 pm
BOG
-
DTW
10h 36m
1 stop
American Airlines Logo
6:00 am - 9:17 pm
DTW
-
BOG
16h 17m
1 stop
$672American Airlines
Thu, Jul 16 - Mon, Jul 27
American Airlines Logo
12:20 pm - 12:41 am
BOG
-
DTW
11h 21m
2 stops
American Airlines Logo
6:00 am - 9:17 pm
DTW
-
BOG
16h 17m
1 stop
$677American Airlines
Fri, Sep 4 - Sun, Sep 20
Delta Logo
12:15 am - 5:19 pm
LIM
-
DTW
16h 04m
2 stops
Delta Logo
10:15 am - 9:00 pm
DTW
-
LIM
11h 45m
1 stop
$728Delta
Wed, Jul 15 - Sat, Oct 3
Multiple Airlines Logo
2:15 pm - 11:59 pm
UIO
-
DTW
32h 44m
2 stops
Multiple Airlines Logo
6:00 am - 1:15 am
DTW
-
UIO
20h 15m
2 stops
$747Multiple Airlines
Mon, Sep 7 - Mon, Sep 14
Delta Logo
11:00 pm - 5:12 pm
SCL
-
DTW
19h 12m
2 stops
Delta Logo
4:00 pm - 6:55 am
DTW
-
SCL
13h 55m
2 stops
$1,066Delta
Tue, Oct 13 - Sun, Oct 25
United Airlines Logo
12:23 pm - 10:30 pm
SCL
-
DTW
35h 07m
2 stops
United Airlines Logo
7:30 pm - 7:50 am
DTW
-
SCL
35h 20m
2 stops
$1,067United Airlines
Useful Info

Good to know

Low seasonOctober
Cheapest flight$256
Best time to beat the crowds with an average 28% drop in price.
Most popular time to fly and prices are also 11% lower on average.
Flight from Medellín to Detroit

FAQs for booking South America to Detroit flights

  • How does KAYAK find such low prices on flights from South America to Detroit?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from South America to Detroit.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from South America to Detroit?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Detroit from South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from South America to Detroit?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Detroit with an airline and back to South America with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from South America to Detroit?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Detroit from South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 5 airlines serving from South America to Detroit

 
Need help choosing which airline to fly with from South America to Detroit? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8416 reviews
8.1Boarding
7.2Food
8.5Crew
7.8Comfort
7.8Entertainment
Airline reviews

Boarding in Amsterdam is always chaotic. More complicated than needs to be ( boarding pass checked twice, once for general security, then by the airline). The bathrooms on this flight are dirty, and smelly. The food was mediocre at best The crew was decent

6.0 GoodAnonymous, May 2026
AMS - DTW
Read more Delta reviews

Boarding in Amsterdam is always chaotic. More complicated than needs to be ( boarding pass checked twice, once for general security, then by the airline). The bathrooms on this flight are dirty, and smelly. The food was mediocre at best The crew was decent

Didn't like sitting on the waiting pad for 30 minutes right after departing the gate. If you're going to do that, just don't board so people can still get up and walk around in the terminal. My luggage was damaged by the baggage handlers.

The gentleman at the gate I think his name is RIE was exceptional

Loved the crew! Sucks that we went from 1 hour and 8 minute layover to a 3 hour layover. But weather sucks like that.

Everything could have benn better. Short fly, no food, no entertainment and no wifi.

On the return flight, flight attendant Britt went out of her way to inform passengers that several of us had tight connections.

Flight late, the waited for a long time for “personal” to arrive at gate to dock the plane in Rochester. So annoying. This flight was expected, why aren’t personel available for the jet bridge?

Kayak botched up the booking, i had to call delta and fix. In the process Delta failed to honor my comfort plus seat assignment that i had previously.

First class is comfortable. Enjoyed a movie and was able to relax compared to coach.

No pilots so we were two hours late taking off and then no gate agents when we arrived in Salt Lake.

Flight was delayed but more than 90 minutes. This caused me to miss my available windows for pick-up by a friend. I had to pay $125 for an uber back home from the airport which was an added expense that I had not budgeted for my trip. Staff was friendly.

Uncomfortable plastic seats even in premium economy. No free wifi. Even paid wifi was spotty to nonexistent. Bad food. Much worse than economy on foreign carriers like Qantas.

How can you rate a flight when it is canceled after you leave the gate & 3 hours into sitting there or in remote area of airport after mechanical problems

Seat pitch is horrible especially on the 15 hour flight. Gate crew at SFO was Outstanding. The flight crew was also great.

Had a one hour delay due to mechanical issue. I didn’t think I’d be able to make my connecting flight, but they waited for me and greeted me when I arrived to help things run smooth.

Broken tray table. Erratic service. Premium economy is more economy than premium- other airlines treat PE much better. No lounge access.

6 1/2 hours from Tampa to SFO on a Boeing 737. Cramped. No Service. No real food. One pass for coffee at the beginning and a second pass THREE hours later. And check-in in Tampa was nasty even by United standards. And I am at almost TWO million miles on United. It's a non-stop. But terrible service.

MY FAMILY'S LUGGAGE WAS LOST FROM ROME TO BARI. I WAS THE ONLY ONE THAT RECEIVED MY LUGGAGE FROM ROME TO BARI. AFTER DEPLANING IN BARI, WE WASTED A LOT OF TIME AT BAG CLAIMS LOST AND FOUND REPORTING THE CLAIM AND PLEADING FOR THE BAGS TO BE DELIVERED THE NEXT DAY. WE WERE TOLD THAT IT TAKES 3 DAYS MINIMUM TO DELIVER. MY DAUGHTER AND MY GIRLFRIEND NEEDED THEIR PERSONAL THINGS AND WE WERE STAYING 3 HOURS AWAY FROM THE BARI AIRPORT. WE HAD TO DRIVE 3 HOURS TO THE AIRPORT TO COLLECT OUR LOST LUGGAGE THE NEXT DAY. WE ARE NOT HAPPY WITH THE EXPERIENCE

We had a delay, but thankfully I made it to my connection. Overall it went smooth

The flight had a delay but I made it to my connection. Flight was smooth overall

It was fine for what it was. It’s not luxury travel but it was efficient, for the most part. Having my carry-on transferred into luggage however, was unwelcome.

Jet blue is always good - the one weird thing was that they started boarding about 20-30 minutes before the official boarding time on the app. Just something to be aware of!

We had better-than-average leg room and I loved the access to shows and movies. During boarding, we could not hear the agent even though we were close to the boarding door, which was kind of scary when we realized that half of the passengers had already boarded. Also, the entertainment was awesome, but I could not hear the movie as well as I would have liked, because my headphones were crappy. It would have been better if I could connect my own ear buds via Bluetooth or if JetBlue provided headphones.

On time, friendly attendants, quick wheelchair assistance and help checking in bags. Also appreciated change in seats, more forward to make it easier for my 97 year old mother to board and exit the plane. Thank you, JetBlue!

Flight did not have onboard charging and TV screen flickering.

I was seated next to an autistic child who was out of control and had a child behind me kicking my seat for most of the trip. I will never fly JetBlue again. Ever. I don't care how cheap it is. It's terrible.

Boarding process was terrible. No assigned seat until the gate, then a long line to get seat assignment.

This was the first flight I've taken since pre-pandemic. I was pleased with how orderly the boarding and disembarking went. The seats were comfortable. I loved that there was no "first class'. The attendants and passengers I met were all very friendly and welcoming.

Boarding was easy. Provided drinks and snacks. Good aircraft and staff

Not very happy because of the long delaying which causes our luggages were not on the connection flight and nearly missed our connection flight.

Movies on my phone are great. It would be nice to have a gluten free snack option.

It was what i expected. I like the movies you can access from your phone. It would be nice if there was a gluten free snack offered. But I did bring my own snack knowing there would not be a gluten free option

The flight was peaceful, just s slight turbulence, pilots and crews were all nice and made a great job! Arrived safely in the Philippines. Thank you ya’ll!

Ontario airport boarding was very easy to park and access, is clean and TSA took 10 minutes total. Check-in was a breeze and cruise was very nice.

American Airlines II: Delay Boogaloo. Multiple gate changes, delays, boarded and then MORE delays. I hate to say this won’t matter, but posting stuff about major corporations in 2026 is a post-modern “scream into the void.” Was multiple hours late coming home, so there you go.

Awful, tons of delays, I got into Chicago multiple hours late meaning I hit the very traffic I tried so desperately to avoid. Just empty apologies from American Airlines text alerts. Trash behavior from a trash airline.

The flight attendants were very friendly, efficient, and helpful. The plane was ahead of schedule, and it all went very smoothly. Thank you.

They lost my baggage and I am still struggling to the information and update

We got delayed getting out of DFW for broken overhead bins. Once the flight got underway the captain kept the seatbelt sign lit the entire flight despite little perceptible turbulence, preventing use of the rest rooms and any sort of refreshment service in the main cabin.

Flight delays for communication overall not a good experience uncomfortable on the plane. Person in front of me reclined his seat, putting them inches from my lap.

My flight today was cancelled because it was Spirit Airlines but have received no refund.

THEY WENT OUT OF BUSINESS AND CANCELED FLIGHT. REPLACEMENT FLIGHTS WERE 300% HIGHER SO MY FAMILY COULD NOT GET TOGETHER. WHY AM I GETTING THIS SURVEY?????

If there WAS a flight it would have been EXCELENT..Maybe?

It would have been better IF IT HAD NOT BEEN CANCELED!!!!

There was no flight. Spirit went bankrupt Right before my departure and kayak did not refund me any money. I would like my refund kayak. How can I get it? Please let me know. Thank you

Spirit is awful, and cost me an extra $400. On the flight to the destination they staff was rude and did not even offer water during the flight. On the return flight, while on the way to the terminal, Spirit cancelled the flight. This is the second time this has happened, and I believe they should compensate for the additional cost for incurred for the return flight. Spirit simply offered reimbursement for their cancelled flight, and did not take into consideration the cost for a last-minute flight home. The TSA agents expressed how Spirit often cancels evening/night flights, and shows no concern for the passengers.

They didn’t put my luggage on my transfer so I had to spend the night in Detroit. They said my luggage would be here in the morning and they’re still searching for it. It did not arrive apparently.

We were delayed and the bag charge fees are very expensive.

The flight was supposed to leave at 6:22pm we are just now leaving the gate after deplaning twice at 1:07am.

Food and entertainment see irrelevant to rate them as that’s not really an option anymore. The flight was fast and friendly. The plane was immaculately clean.

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