$220 Find Cheap Flights from South America to Detroit

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight to Detroit departing on 12/10. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$320
Multiple Airlines
Wed 12/17Thu 1/1
MDE - DTW • 1 stop
Cheapest one-way
$152
Spirit Airlines
Wed 12/10
GYE - DTW • 1 stop
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Flight Deals
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Flight Deals

Cheap Flights from South America to Detroit

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from South America to Detroit that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from South America to Detroit

Wed, Dec 17 - Thu, Jan 1
Multiple Airlines Logo
2:25 am - 9:56 pmMDE-DTW
19h 31m1 stop
Multiple Airlines Logo
2:43 pm - 1:28 amDTW-MDE
10h 45m1 stop
$320Multiple Airlines
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Sat, Dec 20 - Thu, Jan 1
Multiple Airlines Logo
2:25 am - 9:12 pmMDE-DTW
18h 47m1 stop
Multiple Airlines Logo
2:43 pm - 1:28 amDTW-MDE
10h 45m1 stop
$336Multiple Airlines
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Wed, Jan 21 - Wed, Jan 28
Spirit Airlines Logo
1:45 pm - 11:41 pmBOG-DTW
9h 56m1 stop
Spirit Airlines Logo
5:30 am - 2:07 pmDTW-BOG
8h 37m1 stop
$342Spirit Airlines
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Fri, Dec 26 - Sun, Jan 4
LATAM Airlines Logo
11:10 pm - 10:32 amSCL-DTW
13h 22m1 stop
LATAM Airlines Logo
10:20 am - 6:55 amDTW-SCL
18h 35m1 stop
$667LATAM Airlines
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Wed, Jan 21 - Wed, Jan 28
Delta Logo
11:30 pm - 9:52 pmSCL-DTW
24h 22m1 stop
Delta Logo
8:25 am - 5:35 amDTW-SCL
19h 10m1 stop
$685Delta
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Thu, Dec 25 - Mon, Dec 29
Delta Logo
9:30 pm - 10:29 amSCL-DTW
14h 59m1 stop
Delta Logo
4:56 pm - 7:40 amDTW-SCL
12h 44m1 stop
$694Delta
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Tue, Jan 20 - Thu, Jan 29
LATAM Airlines Logo
9:30 pm - 11:01 amSCL-DTW
15h 31m1 stop
LATAM Airlines Logo
10:05 am - 6:55 amDTW-SCL
18h 50m1 stop
$695LATAM Airlines
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Thu, Dec 25 - Mon, Dec 29
United Airlines Logo
10:45 pm - 1:15 pmSCL-DTW
16h 30m2 stops
United Airlines Logo
9:12 am - 8:50 amDTW-SCL
21h 38m2 stops
$699United Airlines
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Fri, Feb 20 - Wed, May 20
American Airlines Logo
7:30 am - 11:59 pmUIO-DTW
16h 29m1 stop
American Airlines Logo
6:17 am - 8:45 pmDTW-UIO
15h 28m1 stop
$858American Airlines
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Mon, Apr 6 - Mon, Apr 13
American Airlines Logo
11:00 pm - 10:45 pmGIG-DTW
24h 45m1 stop
American Airlines Logo
5:56 pm - 8:20 amDTW-GIG
13h 24m1 stop
$940American Airlines
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Useful Info

Good to know

Low seasonOctober
Cheapest flight$152
Best time to beat the crowds with an average 24% drop in price.
Most popular time to fly with an average 8% increase in price.
Flight from Guayaquil to Detroit

FAQs for booking South America to Detroit flights

  • How does KAYAK find such low prices on flights from South America to Detroit?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from South America to Detroit.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from South America to Detroit?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Detroit from South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from South America to Detroit?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Detroit with an airline and back to South America with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from South America to Detroit?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Detroit from South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 5 airlines serving from South America to Detroit

 
Need help choosing which airline to fly with from South America to Detroit? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8011 reviews
8.1Boarding
7.9Comfort
7.9Entertainment
8.5Crew
7.3Food
Airline reviews

Good seats in Main cabin, excellent service and excellent landing

10.0 ExcellentAnonymous, Dec 2025SEA - MSP
Read more Delta reviews

Good seats in Main cabin, excellent service and excellent landing

My flight was cancelled with no explanation after I had already cleared security. I was given 4 options to rebook, only one being non-stop like I had paid for. I grabbed it. It was 4 plus hours later and then took off even later. Biggest complaint is that I booked early and had an aisle seat. They gave me a "window" seat in front of the exit row, so the seat did not decline. I weigh all of 103 #s and it was tight for me! For what I paid, I feel I was kind of ripped off. I think they should have given me the empty comfort seat for the inconvenience. There was no apology nor any explanation as to why the flight was cancelled. My guess is it benefitted Delta in some way.

Very smooth, on-time, and pleasantly uneventful flight. The team at the gate and on board were professional and genuinely courteous. The pilot kept us well updated throughout, and both takeoff and landing were steady and enjoyable without any drama. Just a good, solid flight. Thank you! 💗

Staff was exceptional! Everyone was kind, professional and friendly making the trip very pleasant. Thank you!

No lunch on a x-country flight scheduled for 10:50 am departure, arrived 5+ hrs later. That requires a black box label before you pay for the tickets. Worst, when I checked in online, it's specifically said that lunch was served on his flight for economy Plus passengers.

We had a lot of really rough weather but that was not Delta's fault. Pilot was amazing.

One of the best airlines that I flew on, the flight attendants were very attentive and professional.

First, Delta needs more flights to/from Miami. Second, a 1000pm leaving at 1230pm is unacceptable from their biggest airport world hub. Another aircraft could have been used such as the aircraft scheduled to be used in the morning for that exact same route. Yes, I did get me there but the lack of sleep the next day didn't help me enjoy my entire trip since I was busy with activities during the weekend. This can be and is expected from Spirit (going bankrupt) and Frontier (despite they're nickel and dimers). But from Delta's World Hub? That's totally unacceptable!

This flight was straightforward and without difficulty. Service was OK, but I continue to be underwhelmed by level of attention given to Sky Priority passengers.

My experience on any Delta flight is always overshadowed by the time Delta removed me from a flight for no apparent reason.

Good flight, boarding ok and crew very nice. Flight was not full so I was able to be very comfortable. Blanket and pillow provided with was good as it was very cold during the flight . Food was very good(small snack sandwich and an excellent piece of orange cake). Overall good flight, no complaints.

Wish the seats were a little more comfortable.. it was a 6 hrs nonstop trip. But the crew was courteous and w a smile

I like this airline a lot no problems at all, except being forced to check a carry-on bag ., Overall very good airline

Check in -- in business took over 30 mins as there was only one attendant. Boarding was also a mess. The seat was too narrow and was not working properly. Food was very bad and the entertainment very poor. Crew was very polite and helpful, in fairness.

The plane broke down at the Lima stopover and they offered to put me on a flight the be t day but I had to be back in LA that morning and so I had to buy another ticket from Avianca and United for $2k I asked LATAM for compensation and received none. Very bad experience

Poor handling of carry on luggage. We had a 8 hour stop in Santiago, are over 70 and, in spite of paying full fare they wanted to send carry on to luggage hold. No empathy. We had to show that several group 4/5 passengers were not sending their carry ons before they finally let Is keep them. Very poor .

Just to drop my already labeled bag it took 50 minutes inline. Completely disappointed with Latam operation at GRU

The flight was late. Please do not delay next time.

Bought a ticket that included a bag and they still charged me to check it in, latam is the worst airline.

I never got this flight. You sent me to Chile!!! And from Chile I got the other flight to São Paulo... I've arrived 7h latter than I was supposed to arrive because of Delta delays.

Flight was delayed 8 times. We were sitting at the airport for 14 hours. We got 2 hours of sleep (if that) on what was not meant to be a red-eye.

It was probably one of the worst flights I’ve been on. The restrooms were never cleaned or stocked. The food was very subpar, and i usually enjoy airline food, so I was disappointed. It was just all around a bad experience. The only saving grace was the flight attendants.

After a delay at the gate, C3, at Ohare on Sunday, I left my Blk ski coat on the bench at the gate, lost! Please review my lob claim, thx.

Very bad! They kept delaying my flight and wouldn’t do anything about it

They brought an empty plane to the gate. Then a flight delay was announced for maintenance and waiting on a part. I was then put on a flight to San Francisco instead with a connecting flight to my final destination. Arrived at my final destination 2 hours late.

The only downside was my cell phone charger wouldn’t work in the charging port but everyone else’s would work in them all. My cell phone cable works fine in my hotel room in Frankfurt.

Flight team stood out for perzonal attention, kindness at bright cheery attitudes at 8am. Very helpful.

Ot was overall fine. Left on time and had basic snacks. Weather was finicky but that’s not the airlines fault.

Quick and seamless boarding. No entertainment but fast Starlink wifi for this short trip and the staff was really friendly.

We boarded late. The crew at the airport was dismissive. The seat cushion on the plane was uncomfortable.

Liked that it was on time. Staff professional and friendly.

Things were delayed a little. But that didn’t affect my plans. It was fine. I was surprised it was so full thanksgiving day. The crew were friendly and professional.

I appreciated that it was on time, safe and professional. I didn’t like that I wasn’t in a place where I had a window at my window seat. It would have been nice to know that in advance. If it was mentioned in the ticketing, I didn’t notice it.

Overall, an average flight; food options were not the best, and there were bugs on the plane.

My flight was delayed about three hours. I got home at 3:30 in the morning very bad experience.

I like that the crew kept us informed but we moved back and forth from gate to gate before the aircraft arrived.

I like how the crew and pilot kept us updated Even though our flight was slightly delayed. We made up time for it in the air. I really did enjoy my seat and amenities and my trip and value overall.

The flight was delayed multiple times, again no fault of American but again the extra cost, for everything makes it feel like a cheap airline! Especially when flights are outrageously expensive already

The inflight staff is never the issue always the extra and charges american charges! Literally 30 bucks for WiFi! Is insane and then it’s choppy and slow. If you pay for it once you don’t need to pay again for switching aircraft especially when there is flight delays

Horrible. Both legs of my flight were delayed more than 6 hours. No compensation, no screens on the plane, and the plane was not clean.

The ride share experience in JFK is terrible. After traveling on a flight, then you need to take a subway to the last stop to get an uber or lyft. Unacceptable. Bad job JetBlue for permitting JFK and Port Authority to do this to your passengers.

The flight was two hours late due to a computer fault and resulting maintenance. Nothing was offered as compensation beyond bottles of water during the time we were deplaned and waiting in the terminal.

Very pleasant flight attendants. Gate crew rather loud chatting with each other.

Four plus hour flight delay in New York caused us to take off after 11:30pm. We didn’t arrive at our hotel until five hours after check in. Started the trip off feeling exhausted.

Friendly crew. Poor food service maybe due to full flight. All in all, you get what you pay for.

Plane was in bad shape. TV’s and WiFi didn’t work. Plane need a refresh. Not enough room for bags.

Everything was great. I liked the text updates so that I never miss a gate change & I have all the latest info.

I don’t usually fly budget airlines or airlines in the United States. It was as good as any other airline. The seats are comfortable and the airline attendants are not rude & surly. Very nice flight (s).

They have the most inexperienced / rude flight staff I’ve encountered

very difficult boarding process - aggressive passengers not the friendliest crew

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