$276 Find Cheap Flights from South America to Detroit

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight to Detroit departing on 5/25. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from South America to Detroit

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from South America to Detroit that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from South America to Detroit

Wed, Jun 10 - Fri, Aug 7
Multiple Airlines Logo
6:25 am - 12:44 am
MDE
-
DTW
17h 19m
2 stops
Multiple Airlines Logo
6:00 am - 1:25 pm
DTW
-
MDE
8h 25m
1 stop
$567Multiple Airlines
Fri, Jun 5 - Tue, Jun 9
Multiple Airlines Logo
6:00 am - 11:53 pm
BOG
-
DTW
16h 53m
2 stops
Multiple Airlines Logo
12:30 pm - 6:45 pm
DTW
-
BOG
31h 15m
1 stop
$613Multiple Airlines
Wed, Jul 8 - Thu, Jul 16
Multiple Airlines Logo
6:35 am - 6:20 pm
MDE
-
DTW
10h 45m
1 stop
Multiple Airlines Logo
7:25 pm - 3:45 pm
DTW
-
MDE
21h 20m
1 stop
$636Multiple Airlines
Sun, Jun 14 - Sun, Jun 21
Spirit Airlines Logo
2:08 pm - 9:03 am
BOG
-
DTW
17h 55m
1 stop
Spirit Airlines Logo
2:34 pm - 1:05 pm
DTW
-
BOG
23h 31m
2 stops
$650Spirit Airlines
Tue, Sep 22 - Wed, Jan 20
United Airlines Logo
8:30 am - 11:59 pm
BOG
-
DTW
14h 29m
2 stops
United Airlines Logo
9:30 am - 11:05 pm
DTW
-
BOG
13h 35m
1 stop
$657United Airlines
Tue, Jul 7 - Tue, Aug 4
Delta Logo
8:40 am - 9:11 pm
BOG
-
DTW
11h 31m
2 stops
Delta Logo
9:25 am - 7:15 pm
DTW
-
BOG
10h 50m
1 stop
$662Delta
Thu, Aug 13 - Wed, Aug 19
Spirit Airlines Logo
2:26 pm - 11:50 pm
MDE
-
DTW
8h 24m
1 stop
Spirit Airlines Logo
6:00 am - 1:25 pm
DTW
-
MDE
8h 25m
1 stop
$668Spirit Airlines
Thu, Jul 23 - Tue, Aug 11
American Airlines Logo
1:51 pm - 11:56 pm
MDE
-
DTW
9h 05m
1 stop
American Airlines Logo
6:00 am - 12:48 pm
DTW
-
MDE
7h 48m
1 stop
$684American Airlines
Thu, Jun 4 - Tue, Jul 7
American Airlines Logo
8:35 pm - 6:27 pm
EZE
-
DTW
22h 52m
1 stop
American Airlines Logo
6:00 am - 7:00 am
DTW
-
EZE
24h 00m
1 stop
$927American Airlines
Wed, Jun 3 - Sat, Aug 29
Delta Logo
8:10 pm - 12:58 pm
EZE
-
DTW
17h 48m
1 stop
Delta Logo
1:45 pm - 9:45 am
DTW
-
EZE
19h 00m
1 stop
$971Delta
Useful Info

Good to know

Low seasonOctober
Cheapest flight$276
Best time to beat the crowds with an average 25% drop in price.
Most popular time to fly with an average 2% increase in price.
Flight from Medellín to Detroit

FAQs for booking South America to Detroit flights

  • How does KAYAK find such low prices on flights from South America to Detroit?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from South America to Detroit.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from South America to Detroit?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Detroit from South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from South America to Detroit?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Detroit with an airline and back to South America with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from South America to Detroit?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Detroit from South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 5 airlines serving from South America to Detroit

 
Need help choosing which airline to fly with from South America to Detroit? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8458 reviews
7.2Food
7.8Entertainment
7.9Comfort
8.1Boarding
8.5Crew
Airline reviews

Boarding in Amsterdam is always chaotic. More complicated than needs to be ( boarding pass checked twice, once for general security, then by the airline). The bathrooms on this flight are dirty, and smelly. The food was mediocre at best The crew was decent

6.0 GoodAnonymous, May 2026
AMS - DTW
Read more Delta reviews

Boarding in Amsterdam is always chaotic. More complicated than needs to be ( boarding pass checked twice, once for general security, then by the airline). The bathrooms on this flight are dirty, and smelly. The food was mediocre at best The crew was decent

Didn't like sitting on the waiting pad for 30 minutes right after departing the gate. If you're going to do that, just don't board so people can still get up and walk around in the terminal. My luggage was damaged by the baggage handlers.

The gentleman at the gate I think his name is RIE was exceptional

Loved the crew! Sucks that we went from 1 hour and 8 minute layover to a 3 hour layover. But weather sucks like that.

Everything could have benn better. Short fly, no food, no entertainment and no wifi.

On the return flight, flight attendant Britt went out of her way to inform passengers that several of us had tight connections.

Flight late, the waited for a long time for “personal” to arrive at gate to dock the plane in Rochester. So annoying. This flight was expected, why aren’t personel available for the jet bridge?

Kayak botched up the booking, i had to call delta and fix. In the process Delta failed to honor my comfort plus seat assignment that i had previously.

First class is comfortable. Enjoyed a movie and was able to relax compared to coach.

No pilots so we were two hours late taking off and then no gate agents when we arrived in Salt Lake.

Left an hour and a half after the listed time. Up side was it had TV screens on the seat.

No screens or meal options. Freezing cold. Dirty seats. Left late.

O’hsre taxi and deboarding took 40 minutes. Needed 20 minutes extra time between connecting flights to avoid running through terminal.

Seats very comfortable; service efficient and pleasant; flight was on-time; boarding organized.

Seats were not super comfortable and food was not good at all. If I had a chance I would definitely fly a different airline. Of course they are better than any budget airline, but not by much.

Overall a good experience, but no wifi available for free or for purchase and we got wet from condensation or other water source during descent.

Very friendly and helpful staff on board and United was excellent when I missed my onward flight due to the delay in London. Very well organised meant much less stress

Flew steerage class. Short on leg room unless you pay more. No window unless you pay more. Etc. United is trying to squeeze every cent from you. It doesn’t make for any loyalty.

Booked through Kayak Business, had a seat in middle and towards back due to booking rate, not comfortable.

Was great in general, try to respect time and excuses when slight changes have been made, appreciated!

not sure why you ask about food, I n3ver get food on flights except maybe cookies or pretzels. wifi was slow and in and out most of the flight not good.

Everything was fine except the end of the flight. We spent more than an hour circling around Miami due to weather conditions. That was not good.

They lost my bag. ... And I asked them 3 times to 3 different people if my checked bag will maKe it all the way - they all confirmed and at the end it was left at the connection... Bravo

Cancelled BOYH legs of our flight home 30 min before initial boarding

Cancelled the flight half hour before boarding. Then cancelled the connecting flight too.

Delayed due to weather in Dallas (arriving flight arrived late), then boarded the plane only to deboard immediately afterwards, tire needed to be replaced. Flight supposed to depart at 6:15pm but departed at 9:35pm.

Left early arrived early..right amount of talking from pilots..of course had to love the biscuit and water!

I would like a refund for the extra cost the seat I paid for. An oversized person sat next to me and I couldn’t fit on my seat and had to move to another seat.

Boarding gate at LAX was too crowded—two gates next to one another

The flight was delayed about an hour for a maintenance specialist to approve the maintenance repair

Given us a free miles or free flight for waiting for 9 hours I didn’t get home till 5am in the morning and I was supposed to be home at 9:30 touch down.

Easy experience even with the outbound flight being delayed. The seating and space was comfortable and the crew seemed very nice and helpful.

I have always loved JetBlue and had no complaints on my last trip… I will always recommend then. Thank you JetBlue

Excellent price. Everything on time. two bad parts. Kayak said I couldn't sign in for the flight online, but I got an email at the same time from Jet Blue and they let me sign in online. Second bad part was that, although I had provided my known traveler number, neither of my boarding passes, for this flight and the previous one, had TSA pre-check showing.

The comfortability was very good. Except, when entering the craft the the first steward never greeted us upon entering the airplane. He spoke too fast where his words were all jumbled and difficult to understand.

Jet blue was great But the Jayak system Wasa pure nightmare and wasted so much of my time and energy by not giving me a way to access jet blue to check in the flight back I didn’t even get the number confirmation code 24 hours before. Because I didn’t receive the email with the confirmation code I could NoT CHECk IN. I spoke to a kayak third party and they informed me I could not carry a carry on, on the flight which caused me so much extra stress it was just too much. You can be sure I will not be using it recommending your site. Again.

There was a screen but no earphones that could use the older input so I could listen to anything.

My experience with JetBlue was fine BUT I am very upset with Kayak! JetBlue had delayed our scheduled departure by an hour and you NEVER notified me of the change. I did not hear directly from JetBlue because the trip was booked through Kayak, a mistake I will not repeat. Your reminder of the our trip last week still had the WRONG departure time. Our return trip has also changed, and again no notice from you.

Jet blue just had great service overall! Only a little turbulence heading out of Austin, otherwise the jet stream helped the speed of the trip!

Right now I’m still in Jamaica waiting on a flight to New York which I should be in New York from the 30th and I’m here in Jamaica

My flight was canceled the morning of the flight. I had to rebook a flight with a different airline that cost me $900 out of my pocket

Had a flight change had to get a credit.will I get my money back.

Shut down without prior notice End up with spending lots of extra $$$

There was a crack in my window seal. And Spirit is now closed forever.

The company went out of business and now I'm stuck in Ft. Lauderdale. Would not recommend.

Spirit is awful, and cost me an extra $400. On the flight to the destination they staff was rude and did not even offer water during the flight. On the return flight, while on the way to the terminal, Spirit cancelled the flight. This is the second time this has happened, and I believe they should compensate for the additional cost for incurred for the return flight. Spirit simply offered reimbursement for their cancelled flight, and did not take into consideration the cost for a last-minute flight home. The TSA agents expressed how Spirit often cancels evening/night flights, and shows no concern for the passengers.

They didn’t put my luggage on my transfer so I had to spend the night in Detroit. They said my luggage would be here in the morning and they’re still searching for it. It did not arrive apparently.

We were delayed and the bag charge fees are very expensive.

The flight was supposed to leave at 6:22pm we are just now leaving the gate after deplaning twice at 1:07am.

Food and entertainment see irrelevant to rate them as that’s not really an option anymore. The flight was fast and friendly. The plane was immaculately clean.

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