Depew car rentals from $59/day

This price is the cheapest per day rate found by a KAYAK user in the last 48 hours by searching for a car rental in Depew with a pick-up date of 1/12 and drop-off date of 1/19. Fares are subject to change and may not be available at all agencies or on all dates of rental. Click the price to replicate the search for this deal.

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Car Rental Deals
Booking Insights
Car Rental Deals

Cheap car rentals in Depew

Discover the best prices for you by selecting your travel dates on KAYAK.
Mitsubishi Mirage car
Mitsubishi Mirage
or similar Small
2
2
4-5
$59/day
View Deal
Nissan Versa car
Nissan Versa
or similar Small
4
2
2/4
$59/day
View Deal
Toyota Corolla car
Toyota Corolla
or similar Medium
5
3
2/4
$60/day
View Deal
Volkswagen Jetta car
Volkswagen Jetta
or similar Medium
5
3
2/4
$61/day
View Deal
Chevrolet Malibu car
Chevrolet Malibu
or similar Large
5
2
4-5
$61/day
View Deal
Chrysler Pacifica car
Chrysler Pacifica
or similar Van
5
5
4-5
$61/day
View Deal
Class Full-size SUV car
Class Full-size SUV
or similar SUV
5
2
4-5
$85/day
View Deal
Class Premium SUV car
Class Premium SUV
or similar SUV
5
5
4-5
$102/day
View Deal
Nissan Rogue car
Nissan Rogue
or similar SUV
5
3
4-5
$63/day
View Deal
Chevrolet Equinox car
Chevrolet Equinox
or similar SUV
5
3
4-5
$68/day
View Deal
Best rates found by KAYAK users in the past 48 hours.
Booking Insights

Good to know

Most popular car type

Average price

Good deal

Luxury
$34/day
$25/day

KAYAK’s insights & trends for Depew car rentals

Check out the latest trends and booking tips to rent a car in Depew with confidence.

What is the best rental car company in Depew?

Based on ratings and reviews from real users on KAYAK, the best car rental companies in Depew are Hertz (0.0, 26 reviews), Enterprise Rent-A-Car (0.0, 2 reviews), and AutoEurope (0.0).

Hertz
Hertz
Rated 0.0/10
Enterprise Rent-A-Car
Enterprise Rent-A-Car
Rated 0.0/10
AutoEurope
AutoEurope
Rated 0.0/10
Avis
Avis
Rated 0.0/10

What is the most popular rental car in Depew?

Rentals in the SUV category (GMC Yukon or similar) are the most popular option in Depew, costing $96/day on average. Some users have found deals as low as $96/day.

What is the cheapest month to rent a car in Depew?

The cheapest month to rent a car in Depew is October at an average cost of $45/day. January is the most expensive month to rent a car in Depew when prices are $118/day on average, which tends to be 66% above the yearly average rental price for Depew.

What rental car company in Depew has the most locations?

Hertz operates 3 locations in Depew, more than any other rental company.

Find deals

KAYAK’s top tips for renting a car in Depew

  • Driving car rentals Depew is a wonderful way to see this village situated on the east central outskirts of Buffalo in the Buffalo-Niagara falls Metropolitan area. In Depew car rentals, you can get to where you need to be much faster than you could on public transportation, allowing you to take in the local sites such as the Buffalo and Erie County Botanical Gardens, the Theodore Roosevelt Inaugural National Historic Site, and the Buffalo Museum of Science according to your own schedule. In car rentals in Depew, you could drive beyond village limits northeast to Rochester, west into Canada, or southwest down to Pittsburgh.
  • About 5 miles northwest of central Depew, the Buffalo Niagara International Airport (BUF) is an ideal location for getting car rentals in Depew. At BUF, go to the arrivals area and exit, and there you will find rental car counters for a number of nationally recognized agencies. The cars themselves are parked in the nearby airport parking lot, which is also where you will return them.
  • In Depew, rush hour traffic tends to peak from 7 am to 9 am and then again from 3 pm to 5 pm. Because of harsh weather in upstate Western New York, the roads have seen some wear and tear. So, drive cautiously over roads that will have many cracks, patches, and potholes. Another aspect those driving car rentals in Depew should be aware of is the often frustrating timing of traffic lights. Do not be surprised if you find yourself in a lot of stop-and-go traffic, where you arrive at one red light only to pull ahead one block and stop at another red light, and so on.
  • The biggest challenge those driving car rentals in Depew will face is, without a doubt, harsh winter weather. Depew receives well over twice the national average of snowfall each year, so if you drive Depew car rentals anytime from late November through March, be prepared to drive in the snow. For visibility purposes, always clean snow and ice off your car, especially the windows, before you drive. Also, give your windshield and back window time to defrost. If you skid on ice, steer into the skid until you regain control of your car. And if you find yourself becoming mesmerized as you're driving in snow, pull over until visibility becomes clearer. And when you have to drive in the snow, check local Depew reports and stick to plowed roads.
  • 25% of our users found rental cars in Depew for $25 or less
  • Medium rental cars in Depew are around 66% cheaper than other car types, on average

FAQs about renting a car in Depew

  • How much does it cost to rent a car in Depew?

    On average a rental car in Depew costs $34 per day. But prices differ between operators and you can save money through a price comparison of car rental deals from different agencies. The cheapest price for a car rental in Depew found in the last 2 weeks is $34.

  • Which car rental companies are at Buffalo airport (BUF)?

    Car rental companies onsite at Buffalo airport include Hertz and Enterprise Rent-A-Car.

  • Which car rental companies will pick you up at Buffalo airport (BUF)?

    Car rental companies that offer shuttle or pick-up services from Buffalo airport to off-airport locations include Hertz, and Enterprise Rent-A-Car.

  • How can I find car rentals near me in Depew?

    Take a look at our extensive car rental location map to find the best rental cars near you.

  • How much does a Luxury car rental cost in Depew?

    A Luxury car rental in Depew costs $96 per day, on average.

  • How much does a Medium car rental cost in Depew?

    A Medium car rental in Depew costs $32 per day, on average.

  • Should I get insurance when renting a car in Depew?

    Most car rental providers in Depew offer insurance but the level of protection can differ substantially. If you're unsure whether to get extra protection for your car rental in Depew, check out KAYAK's car rental insurance guide.

  • How many car agencies are operating in Depew?

    KAYAK has deals for you to compare from 2 car rental agencies in Depew.

  • What do I need to know before booking a car rental in Depew?

    Finding the right price, understanding the add-ons and staying up to date with policy changes can be a challenge. That’s why KAYAK has produced the ultimate guide to renting a car to help you cut though the jargon and make the right choice for your rental car. Find tips and insights for how to book your rental, what car rental insurance you’ll need, how to deal with a car rental agency and what extra fees to expect (and avoid!).

  • Why should I use KAYAK to rent a car in Depew?

    KAYAK searches thousands of car rental agencies to provide you with offers from all car rental agencies operating in Depew so that you can compare car rental rates, reviews and pick-up and drop-off locations to find the best deal for you.

  • What type of car is recommended for driving in Depew?

    Regardless of the time of year, an SUV makes an ideal choice for car rentals in Depew. In harsh winter weather, an SUV gives you the power and traction that will help you drive in snow. Also, an SUV will give you a more comfortable ride on the rough, weather-damaged roads. In nicer weather, an SUV is ideal for enjoying the many opportunities for outdoor recreation that Depew offers.

  • What's the speed limit in Depew?

    The speed limit for interstates around Sepew, such as I-90, I-190, and I-290 is either 55 mph or 65 mph. The same is true for US-20 running north/south through Depew. Pay attention to posted speed limit signs so that you do not get a citation. Within the village of Depew itself, the maximum speed limit for most roads is 30 mph. However, sections of Broadway, Transit Road, and Walden Avenue have speed limits of 40 mph.

  • Where are the best places to park in Depew?

    In the village of Depew, parking is free on most residential and more urban streets. However, pay attention to posted signs for streets were parking is restricted or prohibited. And on all streets in Depew, you may not park overnight between 2 am and 7 am from November 30 through March 15. If you drive into downtown Buffalo, you'll find parking meters that are enforced Monday through Saturday from 8 am to 5 pm. An average price for a metered parking spot in Buffalo is about $1 per hour.

Depew car rental reviews and directory

 
All ratings and reviews are collected from KAYAK users with a verified car rental booking. Learn how KAYAK collects reviews.

Hertz

No score available yet

3 locations in Depew

Show locations

Locations in Depew

4195 Genesee St

+1 716 630 6556

Monday08:00 - 17:00
Tuesday08:00 - 17:00
Wednesday08:00 - 17:00
Thursday08:00 - 17:00
Friday08:00 - 17:00
Saturday09:00 - 12:00

4195 Genesee St

+1 716 630 6556

Monday08:00 - 17:00
Tuesday08:00 - 17:00
Wednesday08:00 - 17:00
Thursday08:00 - 17:00
Friday08:00 - 17:00
Saturday09:00 - 12:00

4800 Broadway

+1 716 681 5015

Monday07:30 - 17:00
Tuesday07:30 - 17:00
Wednesday07:30 - 17:00
Thursday07:30 - 17:00
Friday07:30 - 17:00

Filters

Reviews

8.0 Very good

Anonymous, Oct 2022

KAYAK
Mis-leading location. I had to walk across the busy street to rent a car from Hertz yet there was Hertz at the Buffalo Airport. Strange. I think that gotta be corrected. Tristan

2.0 Poor

Anonymous, Nov 2021

KAYAK
Office was closed when I got there. Plane was 1 hr late and office was already closed by that time (noon on Sat). Should not have been an option for me to rent at this facility given early closure on a Saturday.

6.0 Okay

Anonymous, Oct 2021

KAYAK
It smelled like someone had been smoking in the car. No good.

10.0 Wonderful

Anonymous, Feb 2021

KAYAK

Pros:

Staff was friendly. Service was quick and vehicle was great!!

1 out of 9

Enterprise Rent-A-Car

No score available yet

2 locations in Depew

Show locations

Locations in Depew

3461 Transit Rd

+1 716 668 9400

Monday08:00 - 17:00
Tuesday08:00 - 17:00
Wednesday08:00 - 17:00
Thursday08:00 - 17:00
Friday08:00 - 17:00
Saturday09:00 - 12:00
Sunday00:00 - 00:00

4200 Genesee St-buffalo Airprt

+1 833 813 5266

Monday06:00 - 23:59
Tuesday06:00 - 23:59
Wednesday06:00 - 23:59
Thursday06:00 - 23:59
Friday06:00 - 23:59
Saturday06:00 - 23:59
Sunday06:00 - 23:59

Filters

Reviews

2.0 Poor

Anonymous, Feb 2025

Premium SUV

KAYAK
This was a miserable experience where the reservation made has not honored by Enterprise Rent-a-car Buffalo airport desk agent or manager. Although booked correctly on your site they decided to tell me not vehicles were available while I had seen multiple vehicles in the parking lot waiting for pick-up.

10.0 Wonderful

Dennis, Jun 2024

Luxury

KAYAK
very professional

1 out of 1

AutoEurope

No score available yet

One location in Depew

Show locations

Locations in Depew

Buffalo Niagara International Airport

Opening times not available

Filters

No reviews available

Avis

No score available yet

One location in Depew

Show locations

Locations in Depew

4200 Genesee Street

+1 716 632 1808

Monday06:30 - 23:5900:00 - 00:00
Tuesday00:00 - 00:0006:30 - 23:59
Wednesday00:00 - 00:0006:30 - 23:59
Thursday00:00 - 00:0006:30 - 23:59
Friday06:30 - 23:5900:00 - 00:00
Saturday00:00 - 00:0006:30 - 23:59
Sunday06:30 - 23:5900:00 - 00:00

Filters

Reviews

6.0 Okay

Anonymous, Nov 2024

Supplier choice

KAYAK
Great.

2.0 Poor

Anonymous, Aug 2024

Intermediate SUV

KAYAK
I would like to talk to someone , I have been charged twice!

2.0 Poor

Ali, Feb 2024

Intermediate

KAYAK
👎🏻👎🏻

2.0 Poor

Anonymous, Oct 2023

Minivan

KAYAK
The line was too big, two people to manage over 100 people, wait was so long that after 2 hours in the line I cancel My reservation

10.0 Wonderful

Anonymous, Apr 2021

KAYAK

Pros:

Yes

8.0 Very good

Anonymous, Mar 2021

KAYAK

Pros:

Good costumers service

Cons:

Nice car

1 out of 7

Budget

No score available yet

One location in Depew

Show locations

Locations in Depew

4200 Genesee Street

+1 716 632 6400

Monday06:30 - 23:5900:00 - 00:00
Tuesday06:30 - 23:5900:00 - 00:00
Wednesday00:00 - 00:0006:30 - 23:59
Thursday00:00 - 00:0006:30 - 23:59
Friday06:30 - 23:5900:00 - 00:00
Saturday06:30 - 23:5900:00 - 00:00
Sunday06:30 - 23:5900:00 - 00:00

Filters

Reviews

2.0 Poor

Rozella, Nov 2025

Intermediate

KAYAK
I did not like it at all. Kayak is only a front runner for another corporation that takes your money and I never got a car when I got to my destination and I haven't gotten all my money back yet. I did not understand that you're not really going to kayak kayak is just looking for cars for somebody else who may or may not get your car for you. I didn't like the experience at all and I never got my money back from kayak. I only got partial funds back from a corporation called QEEQ there you go.

4.0 Mediocre

Anonymous, May 2025

Supplier choice

KAYAK
Add on were added with out me agreeing to them so it cost more than I was told

4.0 Mediocre

Mary, Dec 2024

Economy

KAYAK
Couldn’t reach anyone to confirm they would be at counter spent over an hour on hold. Car had pretty rotten smell.

2.0 Poor

Tom, Sep 2024

Intermediate SUV

KAYAK
Took just under 2 hours to get the car. No one knew where or when our car would be ready

10.0 Wonderful

Anonymous, Jun 2024

Minivan

KAYAK
Super quick and at an airport that is all you can ask for!!!!!!A+++

4.0 Mediocre

Anonymous, Jun 2024

Minivan

KAYAK
At the airport in Buffalo the computers crashed, huge line and slow service. They finally moved everyone downstairs and started processing. Slow and chaotic. Huge delay!

1 out of 16

Dollar

No score available yet

One location in Depew

Show locations

Locations in Depew

4200 Genesee Street

+1 866 434 2226

Monday06:00 - 23:59
Tuesday06:00 - 23:59
Wednesday06:00 - 23:59
Thursday06:00 - 23:59
Friday06:00 - 23:59
Saturday06:00 - 23:59
Sunday06:00 - 23:59

Filters

Reviews

10.0 Wonderful

Shameem, Sep 2025

Intermediate

KAYAK
Excellant

10.0 Wonderful

Anonymous, Jul 2025

Intermediate

KAYAK
I got a brand new car, clean and a hybrid car. That was a nice experience.

2.0 Poor

Anonymous, May 2025

Supplier choice

KAYAK
Bad customer service. They tried to get me to upgrade knowing they would give me a free upgrade if I declined because they did not have a vehicle in my level I selected. The clerk also lied about having to buy the toll pass to go into Canada. The toll pass does not operate in Canada.

2.0 Poor

Anonymous, Sep 2024

Compact

KAYAK
Terrible wait time. Car smelled like cigarette smoke.

2.0 Poor

Anonymous, Aug 2024

Supplier choice

KAYAK
Took two and a half hours past scheduled pick up time to be able to pick up rental. Also no one around to help and give instruction on where to park and drop of keys when I dropped the car off.

2.0 Poor

Anonymous, Aug 2024

Standard SUV

KAYAK
The Buffalo airport car rental was a 3 hour wait. This was terrible with my family of 5, including 5, 8, 10 yr olds. Will never do this again.

1 out of 14

National

No score available yet

One location in Depew

Locations in Depew

4200 Genesee St-buffalo Airprt

+1 833 813 5271

Monday06:00 - 23:59
Tuesday06:00 - 23:59
Wednesday06:00 - 23:59
Thursday06:00 - 23:59
Friday06:00 - 23:59
Saturday06:00 - 23:59
Sunday06:00 - 23:59

Filters

No reviews available

Car rental locations in or near Depew

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Traveling to a place near Depew?

Rent a car at Depew if you plan to visit one of these locations
Bowmansville
Grand Island
Eden
Angola

Everything you need to know for your car rental in Depew

Depew car rental information

Pick-up locationDepew
Car typesSmall, Medium, Large, Van, SUV
Rental locations2
Airport locations0
Popular agenciesEnterprise Rent-A-Car