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Cheap Flights from South America to Chicago

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from South America to Chicago

Tue, Oct 13 - Sun, Oct 25
LATAM Airlines Logo
1:29 pm - 12:46 pmUIO  Quito Mariscal Sucr-ORD Chicago O'Hare Intl
23h 17m2 stops Guayaquil Jose Joaquin de Olmedo New York John F Kennedy Intl
LATAM Airlines Logo
5:27 am - 9:25 pmORD  Chicago O'Hare Intl-UIO Quito Mariscal Sucr
15h 58m1 stop Atlanta Hartsfield-Jackson
$385LATAM Airlines
Mon, Oct 19 - Wed, Oct 28
LATAM Airlines Logo
9:20 am - 9:27 amUIO  Quito Mariscal Sucr-ORD Chicago O'Hare Intl
24h 07m2 stops Guayaquil Jose Joaquin de Olmedo New York John F Kennedy Intl
LATAM Airlines Logo
6:30 am - 11:00 pmORD  Chicago O'Hare Intl-UIO Quito Mariscal Sucr
16h 30m2 stops Atlanta Hartsfield-Jackson Bogotá El Dorado
$385LATAM Airlines
Sun, Oct 25 - Sun, Nov 15
United Airlines Logo
12:35 am - 11:26 pmUIO  Quito Mariscal Sucr-ORD Chicago O'Hare Intl
22h 51m1 stop Houston George Bush Intcntl
United Airlines Logo
7:29 am - 12:30 amORD  Chicago O'Hare Intl-UIO Quito Mariscal Sucr
16h 01m1 stop Houston George Bush Intcntl
$386United Airlines
Sun, Oct 11 - Sun, Oct 18
United Airlines Logo
7:00 am - 11:27 pmUIO  Quito Mariscal Sucr-ORD Chicago O'Hare Intl
16h 27m1 stop Houston George Bush Intcntl
United Airlines Logo
9:38 pm - 11:25 pmORD  Chicago O'Hare Intl-UIO Quito Mariscal Sucr
25h 47m1 stop Houston George Bush Intcntl
$386United Airlines
Thu, Nov 5 - Mon, Nov 16
Delta Logo
12:55 am - 8:38 pmUIO  Quito Mariscal Sucr-ORD Chicago O'Hare Intl
20h 43m1 stop Atlanta Hartsfield-Jackson
Delta Logo
6:49 am - 6:52 pmORD  Chicago O'Hare Intl-UIO Quito Mariscal Sucr
11h 03m2 stops Atlanta Hartsfield-Jackson Miami
$386Delta
Wed, Nov 4 - Wed, Nov 11
Delta Logo
12:55 am - 12:59 pmUIO  Quito Mariscal Sucr-ORD Chicago O'Hare Intl
13h 04m2 stops Atlanta Hartsfield-Jackson Detroit Metropolitan Wayne County
Delta Logo
5:30 am - 6:52 pmORD  Chicago O'Hare Intl-UIO Quito Mariscal Sucr
12h 22m2 stops Atlanta Hartsfield-Jackson Miami
$386Delta
Tue, Jan 26 - Sat, Jan 30
American Airlines Logo
12:49 am - 9:28 amUIO  Quito Mariscal Sucr-ORD Chicago O'Hare Intl
9h 39m1 stop Miami
American Airlines Logo
10:34 am - 11:47 pmORD  Chicago O'Hare Intl-UIO Quito Mariscal Sucr
12h 13m2 stops New York John F Kennedy Intl Miami
$388American Airlines
Thu, Feb 4 - Tue, Feb 9
American Airlines Logo
12:49 am - 9:28 amUIO  Quito Mariscal Sucr-ORD Chicago O'Hare Intl
9h 39m1 stop Miami
American Airlines Logo
6:00 am - 11:47 pmORD  Chicago O'Hare Intl-UIO Quito Mariscal Sucr
16h 47m1 stop Miami
$395American Airlines
Tue, Nov 3 - Mon, Nov 9
Avianca Logo
4:30 am - 8:30 pmUIO  Quito Mariscal Sucr-ORD Chicago O'Hare Intl
17h 00m1 stop Bogotá El Dorado
Avianca Logo
10:30 pm - 5:45 pmORD  Chicago O'Hare Intl-UIO Quito Mariscal Sucr
18h 15m1 stop Bogotá El Dorado
$410Avianca
Sun, Nov 15 - Wed, Nov 25
Avianca Logo
3:30 am - 8:30 pmUIO  Quito Mariscal Sucr-ORD Chicago O'Hare Intl
18h 00m1 stop Bogotá El Dorado
Avianca Logo
10:30 pm - 2:10 pmORD  Chicago O'Hare Intl-UIO Quito Mariscal Sucr
14h 40m1 stop Bogotá El Dorado
$410Avianca
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Good to know

Low season

February

Cheapest flight

$233
Best time to beat the crowds with an average 10% drop in price.
Most popular time to fly with an average 16% increase in price.
Flight from Quito to Chicago O'Hare Airport

FAQs for booking flights from South America to Chicago

  • How does KAYAK find such low prices on flights from South America to Chicago?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from South America to Chicago.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from South America to Chicago?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Chicago from South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from South America to Chicago?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Chicago with an airline and back to South America with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from South America to Chicago?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Chicago from South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 5 airlines serving from South America to Chicago

 
Need help choosing which airline to fly with from South America to Chicago? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.8
DeltaOverall score based on 8541 reviews
7.8Comfort
7.8Entertainment
7.2Food
8.5Crew
8.1Boarding
Airline reviews

Delta was fine though my flight was delayed 4 hours into LGA and my return into ORD involved a taxi of 1+ hour to the gate

4.0 OkayEdith, Aug 2026
Read more Delta reviews

Delta was fine though my flight was delayed 4 hours into LGA and my return into ORD involved a taxi of 1+ hour to the gate

It was as good as it could be. Flying is not a pleasant experience these days.

The plane was very warm the entire time, despite my vents being open. Additionally, we didn't have internet on our personal devices

There was an unruly family behind us that made the short flight miserable!!! The cabin crew did nothing to contain it.

Flight delay was frustrating, also you cannot checkin online without delta app, web browser check-in throw errors

Got on the plane and sat there for an hour before departure.

Cramped seating for me. Luckily it wasn’t a long flight

5 hour delay. They blamed the weather but it was the computer issues they had been dealing with for days.

I usually have a positive experience with Delta. Complimentary upgrades are always nice!

long flights are never truly comfortable but the airline did their best. crew was great and the flight was safe.

Flight Crew Review The crew was absolutely amazing from start to finish! They were friendly, professional, attentive, and genuinely made the flight feel comfortable and enjoyable. Every interaction was pleasant, and they went above and beyond to make sure passengers were taken care of. You could really tell that they cared about providing great service. I truly appreciate their kindness and professionalism and would be happy to fly with this crew again!

stood in line to check in luggage for nearly an hour. very poor service and not excusable

Same as the previous flight as far as comfort and food. Entertainment didn’t have a watchable screen so everything would need to be watched on your own device in which they didn’t have a charging port that accommodated my iPhone. Seats were very uncomfortable. Staff was very friendly.

Do not book it’s a scam! They stole $1200 from me

Flight got delayed; had to go through security three times.

A lot things happened in this trip.The fly should be less stress.

Some of the Air hostesses are not that friendly. Need improvement

We had a great flight just wished they had a tv so we can see a movie that would of made my trip excellent.

I would like a glass of wine or some kind of alcoholic drink.

Very long delay but we just made the connection. The requested wheel chairs were not there so I had to assist/carry BOTH of my parents to the gate while carrying their bags so we could make the connection. The plane had no entertainment system and NO WIFI, legroom zero. Restrooms on ALL of flights were dirty and one restroom did not even work properly. I was surprised to see COPA like this since my flight with them in 2013 was incredible, the seats were amazing and the food options were spectacular. Of course, I see this kind of service on many airlines now, with services and hospitality at an all time low. The worse part of the trip was seeing my 90 year old parents go through hell on these flights and having to try and rush to a gate to make the next flight. Never again

On boarding crew at the airport called in the boarding numbers too early meaning before the previous line was completed resulting in later numbers getting to board ahead. Also she asked those who boarded from number 3 to have the tags in their carry-on bags and leave it in the jet bridge. Most of the overhead bins were empty though. This is more work for the ground staff in addition to more inconvenience for passengers waiting to get their carry-ons from the jet bridge.

ok, butt flght was delyed for 2,5h from Frankfurt, and next Flight to Columbuse same

Flight was great. Almost miss my connecting flight due to late departure from Haneda. Had to run all through airport in Chicago to make the flight. Experience was great for 1st time flyers using ANA Airlines.

Like the fact that the boarding was expedited. But the delay and chaos around the onboarding was not appreciated.

Seats are complete BS for 10 hrs. The guy at counter canceled our return flight from europe. Lufthansa on the way back made United look like a trailer park gathering. If given the opportunity, I will never fly united again. Lufthansa seats werent much better to be fair but the service was a 10 out of 10. Incant express how difficult umited made my trip.

It was a great experience to fly with ANA, the sit is very comfortable.

The flight crew were very helpful. The seats were very close together. There was barely room to sit without touching the person next to you.

I’m an EP on AA every year for more than a decade but this was a very pleasant and surprising experience. Clean and sizable plane for HOU to CHI. 5 row first class. And excellent food in first class the steak option was really good. Your flight attendants even better. Seat 5A

Gluten free snack options and meals that offer both gluten free and dairy free.

Not a bad flight but a long delay boarding and taking off due to the pilot not arriving on time.

Mechanical issues and delays. I get it but bad experience. Turned my 3 hour airport experience into a 9 hours

The baggage process at the gate was terrible. Stay was not friendly at all

Flight was delayed because of mechanical. Could not get landing space which caused me to miss my connection. Messy and not organized.

We landed slightly early but then sat in holding area waiting for our gate to clear out for about an hour, so technically we arrived one hour late at the gate at ORD. The airport may be partially responsible here, but regardless of who is responsible, it was a bad experience to be so close yet unable to get off the plane.

Delays and cancellations. Mechanics weren’t on site. Replacement plane took hours to arrive although it should have arrived within 90 minutes. Flight back was cancelled. Ended up driving over 12 hours and wasting 3 days between everything.

Little bit of trouble getting my KTN and pre-check status onto the ticket, but otherwise the counter staff were friendly and truly concerned to get it right.

The flight could have actually taken place. Canceled flight and no option to rebook that day.

Missed connection from delays and times changing multiple times and then involuntarily booked on another airline next day

The flight was delayed in 30 minute increments for a total of 4 hours and 30 minute delay. All other flights to Chicago left on time except for this one flight. If there is an issue with the inbound flight, just let customers know so they can find another flight right away, Once we got on the plane there was another 30 minute delay taking off at 10:30 at night which is very unusual that a flight wouldn't be ready to take off

My seat had a worn out cushion, which made it a bit uncomfortable. Other than that, the flight was excellent.

Better seats, allow us to upgrade, terrible website, poor telephone service, better equipment

Horrible experience with Avianca, they delayed their flight and when we arrived to NYC, AVIANCA took 1 hr y 30 mins to park the airplane and all passenger get off the plane, it made me lost all my trains to get back home and I came back to my place at 3 am instead of 12 am. On the top of that their plane seat are so uncomfortable and is not enough space and killed my legs and knees, Avianca used to be good when it was a Colombian company, now after Brasilian company bought them, their service quality is bad and their flights are delayed and oversold.

I handed in my suitcase in perfect condition at SAL Airport. And in MIA Airport I received it with one corner broken and the wheels bent.

I like the crew members they're very friendly. Clean plane. The flight was on time. I dont like the comfort my car seat its better that the plane seats. They charge for everything. This airline was very good. Now it's a low cost airline

6 hour flight and have to pay for everything 100 dollars to add a carry-on bag is insane

The check in is the only positive thing in Avianca. The seat is the most uncomfortable I have traveled, the distance is minimal.

Not what it used to be. The sale of food makes them look greedy!

Avianca is not what it used to be. So disappointing

It was horrible. My experience with Avianca. I didn’t know it was Pakistan international Airlines but anyway, whatever it is it is bad horrible you guys need to upgrade everything in those planes. And you guys charge $130 for a carry-on did they wanna let me in with my carry-on that I travel everywhere with the luggage you guys are such a dog thank you

why did we have to go through security mid flight

Traveling to a place near Chicago?

Book flights to Chicago if you plan to visit one of these locations
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Valparaiso
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Everything you need to know for your flight to Chicago

Cabin class types available on flights to South America