VVI - MAD

$665 Find Cheap Flights from Santa Cruz de la Sierra to Madrid

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Santa Cruz de la Sierra to Madrid departing on 4/6. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Madrid

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santa Cruz de la Sierra to Madrid, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santa Cruz de la Sierra to Madrid, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$843
Overall average: $1,015
Iberia
Mon 5/4Sun 5/24
VVI - MAD • Non-stop
Cheapest one-way
$665
Typical prices: $721-$954
LATAM Airlines
Mon 4/6
VVI - MAD • 1 stop
Our travelers' advice
AI-powered summary based on content written by travel experts. AI can make mistakes.
Iberia provides Wi-Fi for messaging and email access.
Air Europa offers speedy Wi-Fi for staying connected.
Expert advice
Expert advice
Expert advice
Expert advice
Top airlines
Iberia
Cheapest • from $843 (round-trip)
Iberia
Best reviews • 7.0 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
When to book
6 weeks
in advance
Our data shows that travelers who book at least 6 weeks in advance save around 33% compared to booking last minute.
Insights
Insights
Insights
Insights
When to travel
April
Cheapest • 15% price drop
March
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Nonstop flights
4 days a week
There are direct flights from Santa Cruz de la Sierra to Madrid 4 days a week: Mon, Tue, Thu, Sat.
Direct flights
Direct flights
Direct flights
Direct flights
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Madrid!
Flight Deals
Booking Insights
Expert advice
Flight Deals

Cheap Flights from Santa Cruz de la Sierra to Madrid (VVI-MAD)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Santa Cruz de la Sierra to Madrid that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Santa Cruz de la Sierra to Madrid

Mon, May 4 - Sun, May 24
Iberia Logo
9:15 pm - 1:55 pm
VVI
-
MAD
10h 40mnonstop
Iberia Logo
9:00 pm - 2:30 am
MAD
-
VVI
11h 30mnonstop
$843Iberia
Thu, Mar 26 - Wed, Apr 15
Iberia Logo
10:05 pm - 1:55 pm
VVI
-
MAD
10h 50mnonstop
Iberia Logo
2:40 pm - 7:40 pm
MAD
-
VVI
11h 00mnonstop
$1,000Iberia
Thu, Mar 26 - Wed, Apr 15
Multiple Airlines Logo
10:05 pm - 1:55 pm
VVI
-
MAD
10h 50mnonstop
Multiple Airlines Logo
1:10 pm - 1:50 am
MAD
-
VVI
18h 40m
1 stop
$1,043Multiple Airlines
Mon, Mar 2 - Tue, Mar 17
Avianca Logo
3:40 am - 11:20 pm
VVI
-
MAD
14h 40m
1 stop
Avianca Logo
6:35 am - 2:35 am
MAD
-
VVI
25h 00m
1 stop
$1,072Avianca
Tue, Mar 3 - Tue, Mar 17
Multiple Airlines Logo
11:00 am - 4:35 am
VVI
-
MAD
36h 35m
3 stops
Multiple Airlines Logo
6:35 am - 2:35 am
MAD
-
VVI
25h 00m
1 stop
$1,080Multiple Airlines
Tue, Mar 3 - Tue, Mar 17
Multiple Airlines Logo
2:45 pm - 11:20 pm
VVI
-
MAD
27h 35m
2 stops
Multiple Airlines Logo
6:35 am - 2:35 am
MAD
-
VVI
25h 00m
1 stop
$1,083Multiple Airlines
Thu, May 28 - Fri, Jun 19
Iberia Logo
9:15 pm - 1:55 pm
VVI
-
MAD
10h 40mnonstop
Iberia Logo
9:00 pm - 2:30 am
MAD
-
VVI
11h 30mnonstop
$1,086Iberia
Wed, Feb 4 - Sun, Feb 22
Avianca Logo
3:40 am - 8:50 am
VVI
-
MAD
24h 10m
1 stop
Avianca Logo
6:35 am - 2:35 am
MAD
-
VVI
25h 00m
1 stop
$1,101Avianca
Tue, May 5 - Wed, Jun 10
Air Europa Logo
12:20 pm - 5:10 am
VVI
-
MAD
10h 50mnonstop
Air Europa Logo
11:35 pm - 4:50 am
MAD
-
VVI
11h 15mnonstop
$1,114Air Europa
Thu, Mar 26 - Tue, Apr 14
LATAM Airlines Logo
5:25 am - 4:25 pm
VVI
-
MAD
30h 00m
1 stop
LATAM Airlines Logo
1:45 am - 4:35 am
MAD
-
VVI
32h 50m
1 stop
$1,134LATAM Airlines
Booking Insights

KAYAK's insights & trends for Santa Cruz de la Sierra to Madrid flights

Get data-powered insights and trends into flights from Santa Cruz de la Sierra to Madrid to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Santa Cruz de la Sierra to Madrid?

The average price of all round-trip flights from Santa Cruz de la Sierra to Madrid clicked on KAYAK for each day over the last 12 months.

If you are looking for a flight deal from Santa Cruz de la Sierra to Madrid, look for departures on Thursdays and avoid leaving on a Saturday, as it's usually the priciest day. When flying back from Madrid, Thursday is the cheapest day to fly and Monday is the most expensive.

What is the cheapest month to fly from Santa Cruz de la Sierra to Madrid?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Santa Cruz de la Sierra to Madrid, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Santa Cruz de la Sierra to Madrid is April, where tickets cost $969 (return) on average. On the other hand, the most expensive months are January and September, where the average cost of round-trip tickets is $1,531 and $1,259 respectively.

Can I save money by flying with a layover from Santa Cruz de la Sierra to Madrid?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

Yes, flying with a layover may cost you more time, but you can also save money on the route, with a 1 stop layover the cheapest option at $952 on average.

How far in advance should I book a flight from Santa Cruz de la Sierra to Madrid?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Santa Cruz de la Sierra to Madrid, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Santa Cruz de la Sierra to Madrid, you should book around 6 weeks before departure, which saves you about 33% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 25 weeks before departure.

Expert advice

Expert advice for your flight from Santa Cruz de la Sierra to Madrid

 
AI-powered summary based on content written by travel experts. AI can make mistakes.
KAYAK teamed up with top travel experts to share the best tips for your journey.
Airlines
Air Europa

Air Europa offers speedy Wi-Fi onboard, ideal for staying connected during long flights.


Air Europa's Business Cabin includes Wi-Fi and VIP lounge access, enhancing comfort on long-haul flights.

Iberia

Iberia's Business Class offers roomy seating with all-aisle access and quality in-flight dining.


Iberia provides Wi-Fi with global coverage, useful for messaging and email during flights.

Our travel experts
Laura Ratliff

Laura Ratliff

Expert on Air Europa

Laura Ratliff

Laura Ratliff

Laura Ratliff is a New York-based writer and editor. She lives in downtown Brooklyn with her husband and their beloved dogs. Originally from Texas, she now considers New York City her home. She typically spends more than 200,000 miles on a plane each year and stays in plenty of hotels.

Read more
Marisa Garcia

Marisa Garcia

Expert on Iberia

Marisa Garcia

Marisa Garcia

Marisa knows planes inside and out, spending 16 years working on aircraft in hangars at airports around the world. She is an aviation industry expert, specialized in airline interiors and regulations. Ten years ago, she pivoted to journalism. She shares her insights in leading aviation, travel, and business publications and on her site FlightChic.

Read more

Good to know

Low seasonFebruary
Cheapest flight$665
Best time to beat the crowds with an average 4% drop in price.
Most popular time to fly and prices are also 5% lower on average.
Flight from Santa Cruz de la Sierra to Madrid

When to book flights from Santa Cruz de la Sierra to Madrid

Are your dates flexible? Find out the best times to travel from Santa Cruz de la Sierra to Madrid based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Santa Cruz de la Sierra to Madrid

  • What is the cheapest flight from Santa Cruz de la Sierra to Madrid?

    In the last 3 days, the lowest price for a flight from Santa Cruz de la Sierra to Madrid was $665 for a one-way ticket and $843 for a round-trip.

  • Do I need a passport to fly between Santa Cruz de la Sierra and Madrid?

    A passport is required to fly from Santa Cruz de la Sierra to Madrid.

  • Which aircraft models fly most regularly from Santa Cruz de la Sierra to Madrid?

    The Airbus A330-200 is the aircraft model that flies most regularly on the Santa Cruz de la Sierra to Madrid flight route.

  • Which airline alliances offer flights from Santa Cruz de la Sierra to Madrid?

    oneworld, Star Alliance, and SkyTeam are the airline alliances operating flights between Santa Cruz de la Sierra and Madrid, with oneworld being the most commonly used for this route.

  • On which days can I fly direct from Santa Cruz de la Sierra to Madrid?

    You can catch a nonstop flight from Santa Cruz de la Sierra to Madrid on on Monday, Tuesday, Thursday, and Saturday.

  • Which is the best airline for flights from Santa Cruz de la Sierra to Madrid, Iberia or Air Europa?

    The two airlines most popular with KAYAK users for flights from Santa Cruz de la Sierra to Madrid are Iberia and Air Europa. With an average price for the route of $832 and an overall rating of 7.0, Iberia is the most popular choice. Air Europa is also a great choice for the route, with an average price of $1,243 and an overall rating of 6.9.

  • How does KAYAK find such low prices on flights from Santa Cruz de la Sierra to Madrid?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Santa Cruz de la Sierra to Madrid.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Santa Cruz de la Sierra to Madrid?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Madrid from Santa Cruz de la Sierra is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Santa Cruz de la Sierra to Madrid?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Madrid with an airline and back to Santa Cruz de la Sierra with another airline. Booking your flights between Santa Cruz de la Sierra and MAD can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Santa Cruz de la Sierra to Madrid?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Madrid from Santa Cruz de la Sierra up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from Santa Cruz de la Sierra to Madrid

  • Looking for a cheap flight? 25% of our users found flights on this route for $957 or less one-way and $1,275 or less round-trip.

Prefer to fly direct from Santa Cruz de la Sierra to Madrid?

 
Direct data is based off flight results for the next 60 days. Find direct flights from all airlines flying direct from Santa Cruz de la Sierra Viru Viru Intl to Madrid Barajas.
Find which airlines fly direct from Santa Cruz de la Sierra Viru Viru Intl Airport to Madrid Barajas Airport, which days they fly and book direct flights.

Direct departures

Santa Cruz de la Sierra Viru Viru Intl to Madrid Barajas

Monday

BoA

BoA

Tuesday

Air Europa, BoA

Air Europa, BoA

Thursday

Air Europa, BoA

Air Europa, BoA

Saturday

Air Europa, BoA

Air Europa, BoA

See more direct flights

Direct returns

Madrid Barajas to Santa Cruz de la Sierra Viru Viru Intl

Monday

Air Europa

Air Europa

Wednesday

Air Europa, BoA

Air Europa, BoA

Friday

BoA

BoA

Saturday

Air Europa

Air Europa

Sunday

BoA

BoA

See more direct flights

Reviews of the top 4 airlines serving from Santa Cruz de la Sierra to Madrid

 
See real verified KAYAK customer reviews for airlines flying from Santa Cruz de la Sierra to Madrid. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Santa Cruz de la Sierra to Madrid? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.0
IberiaOverall score based on 3091 reviews
6.6Entertainment
7.1Boarding
6.7Comfort
7.7Crew
6.4Food
Airline reviews

It was fine, older plane with limited entertainment, otherwise fine.

8.0 ExcellentMike, Dec 2025
TFS - MAD
Read more Iberia reviews

It was fine, older plane with limited entertainment, otherwise fine.

the seats were so cramped you could barely move. it was difficult to eat when passengers would recline their seats. the seats were so flimsy and unstable that whenever someone got in and out of their seat, it bounced like a spring back in your face. the movies were nice. the food was terrible. even though the conditions were terrible, they tried to pressure passengers to relocate their seats to accommodate adults who were related and wanted to sit next to each other, even after the passengers expressed that they did not want to move for that purpose. on the connecting flight, the “service” consisted of items for purchase. even though the flight was only 45 minutes, once again passengers (including me) were pressured to relocate for people to sit next to each other. they couldn’t be apart for 45 minutes? this was much less compelling than being apart for an 8 hour flight.

Everything went smoothly, and we even arrived 40min earlier than scheduled, on an Orland-Madrid route.

The staff was very nice and helpful. Some of the best crew I have met.

Bad experience. The seat room are very tight. The food is not good and the breakfast has no hot drink.

Excellent. Thanks to United Star Alliance, since economy was overbooked, I’m grateful to have been upgraded to Business Class.

Good plane, excellent food, crew and entertainment. Seats in business could use an upgrade

Disaster. Downgraded. Zero apology. No effort or coordination between gate and crew. Awful seat blocked by door emergency slide box. Iberia is a mess. App never works. Avoid this airline.

We departed late but made up most of the time in flight. Our ticket was pure economy, so it wasn’t anything fancy; however, I heard that we arrived in Madrid at the exact same time that First Class passengers arrived! Overall, our experience was similar to what we had on other American Airlines transatlantic flights - good value at a reasonable price. We were even able to get our carry-on baggage onto the plane without needing to gate check it.

Flight was OK. Waiting for luggage in Madrid for 55 minutes, unacceptable

No WiFi on the plane. Crew was insensitive to my medical supplies and medicine in my carry on. If the crew was monitoring passengers putting 2 bags in overhead bins there would be room. We sat for 2 hours extra. Iberojet is horrible never again.

There was no water in one of the sinks in the executive area, which is unacceptable as we could not wash our hands after using the restroom

Like I said the experience was mediocre. Nothing special about this airline.

This flight was delayed by more than an hour. The seats are uncomfortable ans do not recline properly. I prepurchased a wifi pass, but wifi was not working on this flight at all. The food was bland.

Food situation was bad. Also movie choices when compared to other airlines was terrible. Seats very narrow. My tv didn’t work.

I was not allowed to cancel the flight, customer service is atrocious

Great staff, just very far from the main terminal, had to run to connect my flight. I had 90 minutes to spare. But my flight from Chicago was delayed also.

My luggage is lost and nowhere to be found, no response from airline

Boarding was a shitshow. Had to bus to the gate. No separate bus and boarding process for Business Class.

The plane was very old, no power outlets. We also had to wait a long time to board. They kept moving us to different lines before we actually could step foot on the plane. We ended up being delayed an hour but we were never told or informed for any reason. After the meal I asked for a coffee which the flight attendant forgot and I had to ask again. Overall not the worst but not the best experience.

Unfortunately had horrible experience Originally booked business class from La Paz to Miami Flight was delayed for 2 hours with no clear explanation

Our flight was canceled and we were put on a different flight, but we were never notified of the change until we checked in. BOA provides no beverage service during the flight and there is no in-flight entertainment. Airline staff tried to tell us that we were not allowed one personal item and one carry-on bag per person, but instead that we were only allowed one item aboard per person, which contradicts their written luggage policy. Airline staff also claimed that a car seat counted against our carry-on allowance, even though our child had his own ticket and is required to use a car seat on board per airline policy.

The crew was great, professional and polite. Good meal too. The flight was full and we departed on time out of Miami. I did feel cramped in my seat for the long overnight flight, which made it hard to sleep

This airline and their crew is so professional and kind, the trip was short and easy.

It was a very smooth process. Everything about the Airline like a well oiled machine.

Muy horrible experiencia, cambiaron dos veces la hora del vuelo resultando en una espera exagerada. No dan información oportuna. Abordadnos el avión retrasado el vuelo y esperamos dentro del avión por 35’ más mientras subían como 6 carros de cajas al avión. Muy mala logística y servicio.

6 horas de retraso en el vuelo sin ninguna explicación por parte de la aerolínea.

Always late, the service is a sandwich, no comfort at all…

They had a problem with their air conditioning system and we almost had heat strokes because they blasted HEATED AIR for almost 40 minutes and there was literally no air. This is the worst airline in Bolivia. Can't believe we have no other options sometimes.

BOA is truly the worst airline in Bolivia. It's a shame we sometimes need to use it cause we have no more options.

only a bag of chips and a bottle of water in business class was served

Provide free food and drinks on an international flight. Add updated head rests

We found the chairs to be really uncomfortable. It’s also really unacceptable that no form of food or drink is included in a 6+ hour flight

Here we have another airline flying to Guatemala but doesn't have a plus or a less, just in the middle. Why? Well, first we don't have even free water Movie selection is poor Seats don't recline in some places Food selection is carb based Forgot to mention, customer service on the web is the worst. Good things; Very reliable on schedule Kind crew

I like the crew they're very friendly. I don't like. on five hour flight they not offered snacks. Any drink. Not even coffee

I couldnt recline the seat. Other than that crew was very attentive and helpful. Thsnk you

This low cost airline looks and fells more like a local bus. In a 6 hour flight not being able to recline a seat is torture. The only thing available with no charge is a glass of water provided by, mostly, rude staff. Our luggage didn’t arrive

6 hour flight and have to pay for everything 100 dollars to add a carry-on bag is insane

No food, terms when selling are not clear. To pricy for the service in general

Boarding was excessively slow. They do it by groups in a way that it doesn’t make sense. After business class , ppl that need assistance and any other priority group they should have ppl board from the back to the front. First rows 20+. Then 15+. Then 10, etc. having ppl sitting in the back board last makes no sense. The libe backame long as soon as ppl on rows 10 or so where told to board. The line went all the way up the ramp and tunnel for 25 mins.

Everything you need to know for your flight from Santa Cruz de la Sierra to Madrid

Information on your arrival and departure airports