Is American Airlines the cheapest airline to fly with from Santa Ana to San Francisco?

With an average price of $401 return, American Airlines is not the cheapest airline to fly from Santa Ana to San Francisco with. Instead, for the lowest price, our data suggests flying with Spirit Airlines, where a return flight costs $120 on average.

Does American Airlines fly direct to San Francisco from Santa Ana?

Yes, American Airlines does offer direct flights for the route, with around 40 flights per week.

What’s the cheapest day of the week to fly from Santa Ana to San Francisco with American Airlines?

On average, the cheapest day of the week to fly from Santa Ana to San Francisco with American Airlines is Monday, when prices are around $88. The most expensive day is generally Sunday, where the average price is around $116.

What’s the cheapest month to fly from Santa Ana to San Francisco with American Airlines?

The cheapest month for American Airlines flights to San Francisco from Santa Ana is generally May, where plane tickets cost $148 on average. If possible, try to avoid the most expensive months of September and November, where tickets cost $308 and $313 respectively.

$108 Cheap American Airlines Flights from Santa Ana to San Francisco

SNA - SFO

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Flight Deals

Cheap American Airlines Flight Deals from Santa Ana to San Francisco

Here are some of the best deals found on KAYAK recently from American Airlines for round-trip flights from Santa Ana to San Francisco that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.

Discover the best prices for you by selecting your travel dates on KAYAK.

Round-trip

One-way

Last minute

Direct

Recent round-trip American Airlines flight deals from Santa Ana to San Francisco

Thu, Jan 15 - Mon, Jan 19

9:45 am - 4:34 pm

SNA

SFO

6h 49m1 stop

6:00 am - 11:48 am

SFO

SNA

5h 48m1 stop

$216American Airlines

Sat, Jan 24 - Sat, Jan 24

6:45 am - 8:32 am

SNA

SFO

1h 47mnonstop

11:33 am - 1:14 pm

SFO

SNA

1h 41mnonstop

$252American Airlines

Fri, Jan 16 - Mon, Jan 19

5:51 pm - 7:29 pm

SNA

SFO

1h 38mnonstop

7:00 am - 8:36 am

SFO

SNA

1h 36mnonstop

$257American Airlines

Wed, Apr 8 - Wed, Apr 15

5:05 pm - 10:32 pm

SNA

SFO

5h 27m1 stop

4:19 pm - 5:58 pm

SFO

SNA

1h 39mnonstop

$267American Airlines

Wed, Apr 8 - Mon, Apr 13

5:05 pm - 10:32 pm

SNA

SFO

5h 27m1 stop

4:25 pm - 9:47 pm

SFO

SNA

5h 22m1 stop

$276American Airlines

Fri, Feb 13 - Mon, Feb 16

1:23 pm - 7:14 pm

SNA

SFO

5h 51m1 stop

7:50 am - 9:29 am

SFO

SNA

1h 39mnonstop

$327American Airlines

Thu, Feb 12 - Thu, Feb 12

10:06 am - 11:50 am

SNA

SFO

1h 44mnonstop

1:46 pm - 3:26 pm

SFO

SNA

1h 40mnonstop

$331American Airlines

Fri, Feb 13 - Mon, Feb 16

6:45 am - 12:34 pm

SNA

SFO

5h 49m1 stop

6:00 am - 12:33 pm

SFO

SNA

6h 33m1 stop

$336American Airlines

Mon, Jan 12 - Thu, Jan 15

9:45 am - 4:34 pm

SNA

SFO

6h 49m1 stop

7:00 am - 8:36 am

SFO

SNA

1h 36mnonstop

$345American Airlines

Thu, Jan 8 - Thu, Jan 15

12:38 pm - 7:19 pm

SNA

SFO

6h 41m1 stop

7:00 am - 8:36 am

SFO

SNA

1h 36mnonstop

$347American Airlines

Useful Info

Low season	January
High season	October
Cheapest flight	$108
Average price round-trip	$647

Best time to beat the crowds with an average 36% drop in price.

Most popular time to fly with an average 11% increase in price.

Flight from John Wayne (Santa Ana) to San Francisco

(price for this month)

When to Book Flights with American Airlines from Santa Ana to San Francisco

Average price per month

Flight prices as travel date approaches

Is American Airlines the cheapest airline to fly with from Santa Ana to San Francisco?
With an average price of $401 return, American Airlines is not the cheapest airline to fly from Santa Ana to San Francisco with. Instead, for the lowest price, our data suggests flying with Spirit Airlines, where a return flight costs $120 on average.
What is the cheapest American Airlines flight from Santa Ana to San Francisco?
In the last 3 days, the lowest price for a flight with American Airlines from Santa Ana to San Francisco was $103 for a return flight and $73 for a one-way flight.
Does American Airlines fly direct to San Francisco from Santa Ana?
Yes, American Airlines does offer direct flights for the route, with around 40 flights per week.
What’s the cheapest day of the week to fly from Santa Ana to San Francisco with American Airlines?
On average, the cheapest day of the week to fly from Santa Ana to San Francisco with American Airlines is Monday, when prices are around $88. The most expensive day is generally Sunday, where the average price is around $116.
What’s the cheapest month to fly from Santa Ana to San Francisco with American Airlines?
The cheapest month for American Airlines flights to San Francisco from Santa Ana is generally May, where plane tickets cost $148 on average. If possible, try to avoid the most expensive months of September and November, where tickets cost $308 and $313 respectively.

7.2

Good10,000 verified ratings

7.5Boarding

8.0Crew

6.9Entertainment

6.4Food

7.2Comfort

Cons -

Show reviews that mention

10.0 Wonderful

Tina, Dec 2025

CLT

SAN

It was perfect

10.0 Wonderful

Paul, Dec 2025

SEA

CLT

Great flight - friendly and attentive team! Seats in coach were comfy, but a little cramped - but that is the case with all airlines ;)

6.0 Okay

Dan, Dec 2025

ORD

ALO

The boarding by groups is pointless. The first two groups worked fine, but almost Noone boarded in goups three thru five leaving the vast majority boarding when group six was called. It defeated the purpose of spreading out the crowd.

4.0 Mediocre

Gabriel, Dec 2025

MIA

EZE

I don’t know who decides what food to serve on these flights but I would be so embarrassed if I served this to anyone and call it food…

10.0 Wonderful

Craig, Dec 2025

CHS

PHL

Left early, arrived early

4.0 Mediocre

Joseph, Dec 2025

FLL

DFW

For whatever reason, the flight was not catered -we were told it would be a 45 minute delay waiting for catering - so no food. There were opened candy and peanuts in the seatback pocket. Flight landed early in DFW but due to the assigned gate not being available, we sat on the ground for 30 minutes waiting for the gate to open - making the flight actually arrive at the gate late.

4.0 Mediocre

Verified traveler, Dec 2025

LAX

AKL

Not great. Booked Extra seats and got nothing extra at all. It’s basically a big budget airline.

6.0 Okay

Maria, Dec 2025

LHR

JFK

Delayed 1 hour

10.0 Wonderful

Christopher, Dec 2025

DFW

BNA

The pilot greased the landing and the crew was fantastic.

8.0 Very good

Connie, Dec 2025

MKE

PHX

I bought wifi and most of the flight could not even use it my apps would just spin. I couldn't even listen to music. super frustrating.

Everything you need to know for your flight from Santa Ana to San Francisco

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Frontier flights from Santa Ana to San Francisco

SNA - SFO

$108 Find Cheap American Airlines Flights from Santa Ana to San Francisco

Search hundreds of travel sites at once for deals on American Airlines flights from Santa Ana to San Francisco

Cheap American Airlines Flight Deals from Santa Ana to San Francisco

Recent round-trip American Airlines flight deals from Santa Ana to San Francisco

Recent one-way American Airlines flight deals from Santa Ana to San Francisco

Recent last minute American Airlines flight deals from Santa Ana to San Francisco

Recent direct American Airlines flight deals from Santa Ana to San Francisco

Good to know

When to Book Flights with American Airlines from Santa Ana to San Francisco

FAQs for flying to San Francisco with American Airlines

Is American Airlines the cheapest airline to fly with from Santa Ana to San Francisco?

With an average price of $401 return, American Airlines is not the cheapest airline to fly from Santa Ana to San Francisco with. Instead, for the lowest price, our data suggests flying with Spirit Airlines, where a return flight costs $120 on average.

What is the cheapest American Airlines flight from Santa Ana to San Francisco?

In the last 3 days, the lowest price for a flight with American Airlines from Santa Ana to San Francisco was $103 for a return flight and $73 for a one-way flight.

Does American Airlines fly direct to San Francisco from Santa Ana?

Yes, American Airlines does offer direct flights for the route, with around 40 flights per week.

What’s the cheapest day of the week to fly from Santa Ana to San Francisco with American Airlines?

On average, the cheapest day of the week to fly from Santa Ana to San Francisco with American Airlines is Monday, when prices are around $88. The most expensive day is generally Sunday, where the average price is around $116.

What’s the cheapest month to fly from Santa Ana to San Francisco with American Airlines?

The cheapest month for American Airlines flights to San Francisco from Santa Ana is generally May, where plane tickets cost $148 on average. If possible, try to avoid the most expensive months of September and November, where tickets cost $308 and $313 respectively.

American Airlines Customer Reviews

Cons -

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Everything you need to know for your flight from Santa Ana to San Francisco

Other airlines flying from Santa Ana to San Francisco

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Top American Airlines flights

The most popular destinations for flights with American Airlines according to clicks from KAYAK users. Prices are the lowest found on KAYAK over the last 7 days. Price and availability is not guaranteed.

Cabin class types available on flights to San Francisco

Cabin classes available on flights to Santa Ana. Prices are the lowest found on KAYAK over the last 7 days. Price and availability is not guaranteed.

Complete your trip to San Francisco with a hotel stay or car rental

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The most popular flights on KAYAK according to clicks in the last 2 weeks. Prices are the lowest found on KAYAK over the last 7 days. Price and availability is not guaranteed.

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